KEGG T01008: 281530

Bos taurus (cow): 281530

Entry

281530 CDS T01008

Gene name

THBS1, THBS

Definition

thrombospondin 1

Orthology

K16857

thrombospondin 1

Organism

bta Bos taurus (cow)

Pathway

bta04115	p53 signaling pathway
bta04145	Phagosome
bta04151	PI3K-Akt signaling pathway
bta04350	TGF-beta signaling pathway
bta04510	Focal adhesion
bta04512	ECM-receptor interaction
bta05144	Malaria
bta05205	Proteoglycans in cancer
bta05219	Bladder cancer

Class

Environmental Information Processing; Signal transduction; TGF-beta signaling pathway [PATH:bta04350]
Environmental Information Processing; Signal transduction; PI3K-Akt signaling pathway [PATH:bta04151]
Environmental Information Processing; Signaling molecules and interaction; ECM-receptor interaction [PATH:bta04512]
Cellular Processes; Transport and catabolism; Phagosome [PATH:bta04145]
Cellular Processes; Cell growth and death; p53 signaling pathway [PATH:bta04115]
Cellular Processes; Cell communication; Focal adhesion [PATH:bta04510]
Human Diseases; Cancers; Proteoglycans in cancer [PATH:bta05205]
Human Diseases; Cancers; Bladder cancer [PATH:bta05219]
Human Diseases; Infectious diseases; Malaria [PATH:bta05144]

SSDB

Motif

Pfam:

TSP_C TSP_3 TSP_1 VWC EGF_3 EGF_CA cEGF EGF Laminin_G_2 Laminin_G_1

Other DBs

NCBI-GI:

NCBI-GeneID:

BGD-bta:

Ensembl:

UniProt:

Position

AA seq 1170 aa
MGLAWGLGVLLLLHACGSNRIPESGGDNSVFDIFELTGAARKRSGRRLVKGPDPSSPAFR
IEDANLIPPVPDKKFQDLVDAVRAEKGFLLLASLRQMKKTRGTLLAVERKDHSGQVFSVI
SNGKAGTLDLSLTVQGKQHVVSVEEALLATGQWKSITLFVQEDRAQLYIDCEKMENAELD
VPIQSIFTRDLASIARLRIAKGGVNDNFQGVLQNVRFVFGTTPEDILRNKGCSSSTSVFV
TLDNNVVNGSSPAIRTDYIGHKTKDLQAICGISCDELSSMVLELRGLRTIVTTLQDSIRK
VTEENKELANELRRPPLCYHNGVQYRTGDEWTVDSCTECRCQNSVTICKKVSCPIMPCSN
ATVPDGECCPRCWPSDSADDGWSPWSEWTSCSVTCGNGIQQRGRSCDSLNNRCEGSSVQT
RTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGKARE
TKACQKDSCPINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPKPQFGGKDCVGDVTENQI
CNKQDCPIDGCLSNPCFAGVQCTSYPDGSWKCGACPPGYSGDGVECKDVDECKEVPDACF
NHNGEHRCENTDPGYNCLPCPPRFTGSQPFGRGVEHATANKQVCKPRNPCTDGTHDCNKN
AKCNYLGHYSDPMYRCECKPGYAGNGIICGEDTDLDGWPNEDLLCVANATYHCRKDNCPN
LPNSGQEDYDKDGIGDACDDDDDNDKIPDDRDNCPFHYNPAQYDYDRDDVGDRCDNCPYN
HNPDQADTDNNGEGDACAADIDGDSILNERDNCQYVYNVDQKDTDMDGVGDQCDNCPLEH
NPDQLDSDSDRIGDTCDNNQDIDEDGHQNNLDNCPYVPNANQADHDKDGKGDACDHDDDN
DGIPDDRDNCRLVPNPDQKDSDGDGRGDACKDDFDQDKVPDIDDICPENVDISETDFRRF
QMIPLDPKGTSQNDPNWVVRHQGKELVQTVNCDPGLAVGYDEFNAVDFSGTFFINTERDD
DYAGFVFGYQSSSRFYVVMWKQVTQSYWDTNPTRAQGYSGLSVKVVNSTTGPGEHLRNAL
WHTGNTSGQVRTLWHDPRHIGWKDFTAYRWHLSHRPKTGFIRVVMYEGKKIMADSGPIYD
KTYAGGRLGLFVFSQEMVFFSDLKYECRDS

NT seq 3513 nt +upstreamnt +downstreamnt
atggggctggcctggggactcggtgtcctgctcctgttgcatgcctgcggctccaaccgc
attccagagtctgggggagacaacagtgtgtttgacatctttgaactcaccggagctgcc
cgcaagcggtctgggcgccgactggtgaagggccctgacccttctagcccagctttccgc
atcgaggatgccaacctgatcccccctgtgcctgacaagaagttccaagacctagtggat
gctgtgcgggcggagaaaggtttcctcctcctggcctccctgaggcaaatgaagaagacc
cggggtaccctgctggctgtggagcggaaagaccactctggccaggtcttcagcgtgatc
tccaatggcaaggcgggcaccctggacctgagcctgaccgtgcaggggaagcagcatgtg
gtgtcggtggaagaagcactcctggcgactggccagtggaagagcatcaccctgtttgtg
caggaggacagggcccagctgtacatcgactgtgagaagatggagaatgcggagctggat
gtccccatccagagcatcttcaccagggacctggccagcatcgccaggctccgcattgcc
aaaggaggtgtcaacgacaatttccagggggtgctgcagaatgtaaggtttgtctttgga
accacaccagaagacatcctcaggaacaaaggctgctccagctctaccagtgtctttgtc
acccttgacaacaacgtggtgaatgggtccagccctgccatccgcaccgactacattggc
cacaagacaaaggacctgcaagccatctgtggcatctcatgtgacgagctgtccagcatg
gtcctggagctcaggggtctacgcaccatcgtgaccacgctgcaggacagtatccgcaaa
gtgaccgaagagaacaaagagctggccaacgagctgaggaggcccccactctgctaccac
aacggagtgcagtacaggactggcgacgagtggacggtggacagctgcactgagtgtcgc
tgccagaactcagttaccatctgcaaaaaagtgtcctgtcccatcatgccctgctccaat
gccacagttccggatggagaatgctgcccacggtgctggcccagcgactctgcagacgat
ggctggtccccgtggtctgagtggacctcttgctctgtgacctgtggcaatggaatccag
cagcgtggccgctcctgcgacagcctcaacaacagatgcgagggctcctctgtgcagacg
cggacctgccacatccaggagtgtgacaagagatttaaacaggatggcggctggagccac
tggtccccatggtcatcttgctccgtaacatgtggagacggtgtgatcacaaggatccgg
ctctgcaactcccccagcccccagatgaatgggaagccatgtgagggcaaagcccgggag
accaaagcctgccagaaagactcctgccccatcaatggaggctggggaccttggtcacca
tgggacatctgttctgtcacctgtggaggaggggtacagaaacgtagccggctctgcaac
aaccccaaaccccagtttggaggcaaggactgcgttggtgatgtgacagaaaaccagatc
tgcaacaagcaggactgtcccattgacggatgcctgtccaatccctgctttgctggtgtc
cagtgtaccagctaccctgatggcagctggaagtgtggtgcctgtcccccaggctatagt
ggagatggagtcgagtgcaaagacgttgatgagtgcaaagaagtccctgatgcctgcttc
aaccacaatggagagcacaggtgtgagaacacagaccccggctacaactgcctgccctgc
ccaccgcgcttcactggctcgcagccctttggccggggcgtggaacatgccaccgccaac
aagcaggtatgcaagccccgaaacccctgcacagacgggacacacgactgcaacaagaac
gccaagtgcaactacctgggccactacagcgaccccatgtaccgctgcgagtgcaagcct
ggctacgccggcaacggcatcatctgcggggaggacacagacctggacggctggcccaat
gaggacctgctgtgcgtggccaacgcaacttaccactgcagaaaggataattgccccaac
cttcccaactcagggcaggaagactatgacaaggatggaatcggcgatgcctgcgatgat
gacgatgacaatgataagattccagatgacagggacaactgtccattccattacaaccca
gcccagtacgactatgacagagatgacgtgggagaccgctgtgacaactgcccctacaac
cacaacccagaccaggctgacacagataacaatggggaaggagacgcctgtgcagctgac
attgatggggacagtatcctcaatgaacgggacaactgccagtatgtctacaatgtggac
cagaaagacactgacatggacggggttggtgatcagtgtgacaactgccccctggaacac
aatccagaccagctcgactctgactcggaccgcattggagacacctgtgacaacaatcag
gatattgatgaagacggccaccagaacaatctggacaactgtccctacgtgcccaacgcc
aaccaggctgaccatgacaaggatggcaaaggcgatgcctgtgaccatgatgacgacaat
gatggcattcctgatgaccgggacaactgcaggctggtgcccaatcctgaccagaaggac
tctgatggtgatggtcgaggtgatgcttgcaaagatgattttgaccaggacaaggtgcca
gacattgatgacatctgtcccgaaaatgttgatatcagtgagactgatttccgccgattc
cagatgattcctctagatcccaaagggacatcccagaatgaccctaactgggttgtacgc
catcagggtaaagaactcgtccagactgtcaactgtgaccctggacttgctgtaggttat
gacgaatttaacgccgtggacttcagtggcaccttcttcatcaacaccgagagggatgac
gactatgccggctttgtgtttggctaccagtccagcagccgcttctatgttgtgatgtgg
aagcaagtcactcagtcctactgggacaccaaccccacgagggctcaggggtactctgga
ctttccgtgaaggttgtaaactccaccacggggcctggcgagcacctgcggaatgccctg
tggcacacaggaaacacctctggccaggtgcgcacactgtggcatgaccctcgtcacatt
ggctggaaagatttcactgcctacagatggcatctgagccacaggccaaagacaggtttc
atcagagtggtaatgtatgaagggaagaaaatcatggctgactcaggacccatctatgac
aaaacctatgctggtgggaggctaggcttgttcgtcttctctcaagaaatggtgttcttc
tccgacctgaaatatgaatgcagagactcctaa

All links

Pathway (9)   
   KEGG PATHWAY (9)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (5)   
   UniGene (1)   
   BGD-BTA (1)   
   ENSEMBL-BTA (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (9)   
   RefSeq(nuc) (1)   
   GenBank (4)   
   EMBL (4)   
Protein domain (10)   
   Pfam (10)   
All databases (42)   

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