KEGG   Bos taurus (cow): 281590Help
Entry
281590            CDS       T01008                                 

Gene name
ACACA, ACC1, ACCA
Definition
acetyl-CoA carboxylase alpha (EC:6.4.1.2 6.3.4.14)
Orthology
K11262  
acetyl-CoA carboxylase / biotin carboxylase [EC:6.4.1.2 6.3.4.14]
Organism
bta  Bos taurus (cow)
Pathway
Fatty acid biosynthesis
Pyruvate metabolism
Propanoate metabolism
Metabolic pathways
Fatty acid metabolism
AMPK signaling pathway
Insulin signaling pathway
Module
Fatty acid biosynthesis, initiation
Brite
KEGG Orthology (KO) [BR:bta00001]
 Metabolism
  Overview
   01212 Fatty acid metabolism
    281590 (ACACA)
  Carbohydrate metabolism
   00620 Pyruvate metabolism
    281590 (ACACA)
   00640 Propanoate metabolism
    281590 (ACACA)
  Lipid metabolism
   00061 Fatty acid biosynthesis
    281590 (ACACA)
  Biosynthesis of other secondary metabolites
   00254 Aflatoxin biosynthesis
    281590 (ACACA)
 Environmental Information Processing
  Signal transduction
   04152 AMPK signaling pathway
    281590 (ACACA)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    281590 (ACACA)
Enzymes [BR:bta01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.14  biotin carboxylase
     281590 (ACACA)
  6.4  Forming carbon-carbon bonds
   6.4.1  Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
    6.4.1.2  acetyl-CoA carboxylase
     281590 (ACACA)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
BGD-bta: 
Ensembl: 
UniProt: 
Position
19q13-q14
AA seq 2346 aa AA seqDB search
MDEPSSLAKPLELNQHSRFIIGSVSEDNSEDEISNLVKLDLLEEKEGSLSPASVSSDTLS
DLGISSLQDGLALHMRSSMSGLHLVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEK
VLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPG
GPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQAMWAL
GDKIASSIVAQTAGIPTLPWSGSGLCVDWHENDFSKRILNVPQELYEKGYVKDVDDGLKA
AEEVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEV
QILADQYGNAISLFGRDCSVQRRHQKIIEEAPAAIATPAVFEHMEQCAVKLARMVGYVSA
GTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLYRIKDIRMMY
GVSPWGDAPIDFENSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGY
FSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLET
ESFQLNRIGTGWLDRLIAEKVQAERPDTMLGVVCGALHVADVSLRNSISNFLHSLERGQV
LTAHTLLNTVDVELIYEGVKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDV
SSYTTYMKEEVDRYRITIGNKTCVFEKENDPSVLRSPSAGKLIQYIVEDGGHVFAGQCYA
EIEVMKMVMTLTAAESGCIHYVKRPGAALDPGCVIAKMQLDNPSKVQQAELHTGSLPRIQ
STALRGEKLHRVFHYVLDNLVNVMNGYCLPDPFFSSRVKDWVERLMKTLRDPSLPLLELQ
DIMTSVSGRIPPNVEKSIKKEMAQYASNITSVLCQFPSQQIANILDSHAATLNRKSEREV
FFMNTQSIVQLVQRYRSGIRGHMKAVVMDLLRQYLRVETQFQNGHYDKCVFALREENKSD
MNTVLNYIFSHAQVTRKNLLVTMLIDQLCGRGPTLTDELLNILTELTQLSKTTNAKVALR
ARQVLIASHLPSYELRLNQVESIFLSAIDMYGHQFCIENLQKLILSETSIFDVLPNFFYH
SNQVVRMAALEVYVRRAYIAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNRGNIPTLNRM
SFSSNLNHYGMTHVASVSDVLLDNAFTPPCQRMGGMVSFRTFEDFVRIFDEVMGCFCDSP
PQSPTFPEAGHTSLYDEDKVPRDEPIHILNVAIKTDCDIEDDSLAAMFREFTQQNKATLV
EHGIRRLTFLVAQKDFRKQVNYEVDQRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQ
LELNRMRNFDLTAIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFE
YLQNEGERLLLEAMDELEVAFNNTNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYG
SRLWKLRVLQAELKINIRLTPTGKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQA
YGDKQGPLHGMLINTPYVTKDQLQSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSSQA
FLPPPPLPSDILTYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMTLKSPEYPDGRDIIVI
GNDITYRIGSFGPQEDLLFLRASELARAEGIPRIYVAANSGARIGLAEEIRHMFHVAWVD
PEDPYKGYKYLYLTPQDYKRVSALNSVHCEHVEDEGESRYKITDIIGKEEGLGAENLRGS
GMIAGESSLAYDEIITISLVTCRAIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGR
EVYTSNNQLGGIQIMHNNGVTHSTVCDDFEGVFTVLHWLSYMPKSVYSSVPLLNSKDPID
RVIEFVPTKAPYDPRWMLAGRPHPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGG
IPVGVVAVETRTVELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNREGLPL
MVFANWRGFSGGMKDMYDQVLKFGAYIVDGLRECSQPVMVYIPPQAELRGGSWVVIDPTI
NPRHMEMYADRESRGSVLEPEGTVEIKFRRKDLVKTMRRVDPVYIHLAERLGTPELSVAE
RKELESKLKEREEFLLPIYHQVAVQFADLHDTPGRMQEKGVINDILDWKTSRTFFYWRLR
RLLLEDLVKKKIHNANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDLVEWLEKQLTE
EDGVRSVIEENIKYISRDYVLKQIRSLVQANPEVAMDSIVHMTQHISPTQRAEVVRILST
MDSPST
NT seq 7041 nt NT seq  +upstreamnt  +downstreamnt
atggatgaaccttcttccttggccaaacctctggagctgaaccagcactcccgattcatt
attggctccgtgtctgaagataactcggaggatgagattagcaacctggtgaagctcgac
ctgctggaggagaaggagggctctctgtcgccagcctcggtcagctcagacacgctctct
gacttgggcatctcgagcctccaggatggtctggccttacacatgagatccagcatgtct
ggcttgcacctagtcaagcaaggtcgagaccgaaagaaaatagactcacagcgagatttc
actgtagcctctccagcagaatttgttactcgttttggtgggaataaagtgattgagaag
gttctcattgccaacaatggcattgcagctgtgaaatgcatgagatccatccgccggtgg
tcttatgagatgtttcgaaatgaacgtgcaatccgatttgttgtcatggtcacacctgaa
gacctgaaagccaatgcagaatacattaagatggcggatcactacgtgcccgtgccagga
ggccccaacaacaacaactatgcaaatgtggagttaattcttgacattgctaaaaggatc
cccgtgcaagcagtttgggctggctggggtcatgcttctgagaatcccaagctcccagaa
cttctcttgaaaaatggcatcgccttcatgggtcctccaagccaagccatgtgggctctg
ggggataagatcgcatcttccatagtggctcaaactgctggtatcccaactcttccatgg
agtggcagtggtctttgtgtggactggcacgaaaatgatttttcaaaacgaattttaaat
gttcctcaggaactatatgaaaaaggttatgtgaaggatgtggatgatgggctgaaggca
gcggaggaagttggatatccagtaatgatcaaggcctcagaaggaggaggagggaaggga
atcagaaaagtcaacaatgcagatgacttccctaacctcttccgacaggttcaagctgaa
gttcctgggtctcctatctttgtcatgagactagccaaacagtctcgtcatctggaggtg
cagatcttagcagatcagtatggcaatgctatctctttgtttggtcgtgattgctctgtg
caacgcaggcatcagaagattattgaagaagctcctgctgctattgctactccagcagta
tttgaacatatggaacagtgtgcggtgaaacttgccaggatggttggttatgtgagtgcg
gggactgtggaatacctctacagccaggatggcagcttctactttctggaactgaaccct
cggctacaggtggagcacccctgtacagagatggtggccgatgtcaacctccctgctgcg
cagctccagattgccatggggatccctctgtacagaatcaaggatatccgaatgatgtac
ggggtctctccctggggcgatgctcccattgattttgaaaattcggctcacgttccttgc
ccaaggggccatgttattgctgctcgtatcactagtgaaaatccagatgagggttttaag
cccagctcaggaacagttcaagagctgaattttcgcagcaataagaacgtttggggttat
ttcagtgttgctgctgcaggagggcttcatgaatttgctgattctcagtttggtcactgc
ttttcctggggagaaaaccgagaggaagcaatttcaaacatggttgtggctttgaaggag
ctgtctatccggggcgacttccggaccacagtcgagtacctgatcaaactgctggagact
gaaagctttcagttgaacagaattggcacgggctggctggacagactgatagcagaaaaa
gtacaggcggagcgacctgacaccatgctgggagttgtctgtggggctctccatgtggca
gacgtgagcctgcggaatagcatctccaacttccttcactccttagagaggggtcaagtc
ctcactgctcatacccttctgaatacagtagatgttgaacttatctacgagggagtgaag
tatgtactgaaggtgactcgacagtccccgaactcctacgtggtgatcatgaacggctcg
tgtgtggaagtagacgtgcatcgactgagcgacggtggactgctcttgtcctatgacgtc
agcagttacaccacgtacatgaaggaggaggtggatagatatcgcatcacaattggcaat
aaaacttgtgtgtttgagaaggaaaatgacccttcggtgctgcgctcaccctctgctggg
aagttgatccagtacattgtggaggatggaggccacgtgtttgctggccagtgctatgcc
gagatcgaggtgatgaagatggtaatgaccttaacagccgcagagtctggctgtatccat
tatgtcaagcggcctggagcagctcttgacccgggctgtgtaatagccaaaatgcaactg
gacaaccccagcaaggtccagcaggctgagcttcacacaggcagtctgccacggatccag
agcacagcgctcagaggcgagaagctccaccgagtgttccactatgtcctggataatctg
gtcaatgtgatgaatggatactgccttccagatcctttctttagcagcagggtgaaagac
tgggttgaacggttgatgaagaccctcagagacccctccttgcctctcctagaattgcag
gatatcatgactagcgtctctggtcgtatcccgcccaacgtggaaaagtctatcaagaag
gaaatggctcagtatgccagcaacatcacatccgtgctctgtcagtttcccagccagcag
attgccaacatcctagacagccacgcagccacactgaaccggaaatctgaacgggaagtc
ttcttcatgaacactcagagcatcgtccagctggtgcagaggtaccgcagtggcatccga
ggacacatgaaggctgtggtgatggacctgctgcggcagtacctgcgagtagagacacaa
ttccagaacggtcactatgacaaatgcgtgttcgccctccgggaggagaacaagagtgat
atgaacactgtgctgaactacatcttctctcatgctcaggtcaccaggaagaatcttctg
gtcaccatgcttatcgatcagctgtgtggccggggccccaccctcactgatgagctgctg
aatatcctcacggagctaactcaactcagcaagaccaccaacgcgaaggtggcgctccga
gcacgccaggttcttattgcttcccatttgccatcctatgagcttcgcctcaaccaagtc
gagtctatcttcctatccgccattgacatgtatggacaccagttctgcatcgagaacctg
cagaaactcatcttgtccgaaacgtcgatttttgatgtcctaccaaacttcttctatcac
agcaaccaggtcgtgaggatggcagctctggaggtgtatgttcgaagggcttatatcgcc
tatgaacttaatagcgtacaacaccggcagctgaaggacaacacctgcgtggtggaattc
cagttcatgctgcccacatcgcatccaaatagagggaacatccccacgctaaacagaatg
tccttctcctccaacctcaaccactacggcatgactcacgtagccagtgtcagcgacgtg
ctgctggacaacgcgttcactccgccgtgtcagcggatgggcgggatggtctcttttcgg
acctttgaagattttgtcaggatctttgatgaagtgatgggctgcttctgtgattcccca
ccccaaagcccgacattccctgaggcaggtcacacgtctctgtatgacgaagacaaggtc
cccagggatgaaccaattcacattttgaatgtggctatcaaaacagactgtgacatcgag
gatgacagtctagcagctatgttccgagagtttacccagcaaaacaaagctaccctggtt
gaacatgggatccgacgccttactttcctggttgcacaaaaggatttcaggaaacaagtc
aactatgaagtggatcagagatttcatagagaatttcctaaatttttcacgttccgagca
agggataagtttgaggaagatcgtatctatcgtcacctggagcctgccctagctttccag
ttagagctgaaccggatgagaaattttgaccttactgccatcccgtgtgccaatcacaag
atgcacttgtatcttggggcagccaaggtagaagtgggcacagaagtgacagactacagg
ttctttgttcgtgcaatcatcaggcattctgatctggtcaccaaggaagcttcctttgaa
tatctacaaaatgaaggggagcggctcctcctggaagccatggatgagttggaagtcgcc
tttaacaatacaaatgtccggactgactgcaaccacatcttcctcaactttgttcctaca
gtcatcatggacccatcgaagattgaggaatccgtgcggagcatggtgatgcgctatgga
agtcggctgtggaagctgcgtgtcctccaggcagaactgaaaatcaacattcgcctgaca
ccaactggaaaagcaattcccatccgcctcttcctgacgaacgagtctggctattacttg
gacatcagcctgtacaaggaagtgactgattccaggacagcacagatcatgtttcaggca
tatggagacaaacagggaccattacatggaatgttaatcaacactccgtacgtgaccaaa
gaccagcttcaatccaagaggttccaggcacagtccttagggacaacatacatatatgac
atcccagaaatgtttcggcagtccctgatcaaactctgggaatctatgtcctcccaagca
ttccttccaccgccccctctgccttcagacatactgacgtacactgagctcgtgttggat
gatcaaggtcaactggttcacatgaacaggcttccaggaggaaatgagattggcatggta
gcttggaaaatgacccttaaaagtccagaatatccagacggccgagatatcattgttatt
ggcaatgacatcacttaccgaattgggtcctttggaccccaagaggatttgctgtttctc
agagcttctgagcttgccagggcagagggcatcccacgcatctatgtagcagccaacagt
ggagcaagaattggactggcagaggaaattcgtcatatgtttcacgtggcctgggtagat
cctgaggatccttacaagggatacaaatatttatatctgacccctcaagattacaagaga
gtcagtgctctcaactctgtccattgtgaacatgtggaagatgaaggagaatccaggtac
aagatcactgacattattgggaaggaagaaggacttggagcagagaaccttcgagggtct
ggaatgattgctggggaatcctcgttggcctacgacgagatcatcaccatcagcctggtt
acatgcagggccattgggattggggcttacctcgtccgactgggacagagaaccatccag
gtcgaaaattctcacttaatcctgacaggagctggggccctcaacaaagtcctcggtagg
gaagtatacacctccaacaaccagctggggggcatccagatcatgcacaacaatggggtg
acgcacagcaccgtctgtgacgacttcgagggggtgttcaccgtcctgcactggctgtct
tacatgccgaagagtgtatacagttcagttcctctcctgaactccaaggatccaatagac
agagtcatcgagtttgtgcccacgaaggcgccgtatgaccctcggtggatgctggcaggc
cggcctcacccaacccagaaaggtcagtggttgagtggattttttgactatggctctttc
tcagagatcatgcaaccgtgggcacagactgtggtggttggcagagccaggctaggagga
atacccgtgggagtagttgccgtagaaacccgaacagtggagctgagcatcccggctgat
cctgcaaacctggattctgaagccaagattatccagcaggctggccaggtttggttccca
gactccgcgtttaagacgtatcaggccattaaggacttcaaccgtgaagggctgcctctg
atggtctttgccaactggagaggcttctccggtgggatgaaagatatgtacgaccaggtg
ctgaagttcggcgcttacatcgtggacggcttacgggagtgctcgcagcccgtgatggtc
tacatcccgcctcaggccgagctccgaggcggctcctgggtggtgattgaccccaccatc
aacccgcggcacatggagatgtatgcggaccgcgagagcaggggatccgttctggagccg
gaagggacagtcgaaatcaaattccgcagaaaggatctggtgaaaaccatgcgtcgggtg
gacccagtctacatccacttggctgagcgattgggtacccccgagctcagcgtggccgag
cggaaggagctggagagcaagctgaaggagcgagaggagttcctccttcccatctaccac
caggtggccgtgcagtttgcagacctgcacgacaccccgggccgcatgcaggagaagggg
gtcattaacgacatcctggattggaagacttcacgcaccttcttctactggcggctgagg
cggctgttgctggaggacctggtcaagaagaaaatccacaatgccaatcccgagctgaca
gacggccagatccaggccatgctaaggcgctggtttgtggaggtggagggaaccgtgaag
gcctatgtctgggacaacaacaaggatctggtggagtggctggagaaacagctcacagag
gaagacggcgtccgctcggtgattgaagagaacatcaagtacatcagcagagactacgtc
ctcaagcagatccgcagcttggtccaggccaacccagaggttgccatggattccatcgtc
cacatgacgcagcacatctcgcccacccagcgagcagaagtcgttcggatcctctcgacg
atggactcgccctcaacgtag

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