KEGG T01008: 281872

Bos taurus (cow): 281872

Entry

281872 CDS T01008

Gene name

ITGA2

Definition

integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)

Orthology

K06481

integrin alpha 2

Organism

bta Bos taurus (cow)

Pathway

bta04145	Phagosome
bta04151	PI3K-Akt signaling pathway
bta04510	Focal adhesion
bta04512	ECM-receptor interaction
bta04640	Hematopoietic cell lineage
bta04810	Regulation of actin cytoskeleton
bta05200	Pathways in cancer
bta05205	Proteoglycans in cancer
bta05222	Small cell lung cancer
bta05410	Hypertrophic cardiomyopathy (HCM)
bta05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)
bta05414	Dilated cardiomyopathy

Class

Environmental Information Processing; Signal transduction; PI3K-Akt signaling pathway [PATH:bta04151]
Environmental Information Processing; Signaling molecules and interaction; ECM-receptor interaction [PATH:bta04512]
Cellular Processes; Transport and catabolism; Phagosome [PATH:bta04145]
Cellular Processes; Cell motility; Regulation of actin cytoskeleton [PATH:bta04810]
Cellular Processes; Cell communication; Focal adhesion [PATH:bta04510]
Organismal Systems; Immune system; Hematopoietic cell lineage [PATH:bta04640]
Human Diseases; Cancers; Pathways in cancer [PATH:bta05200]
Human Diseases; Cancers; Proteoglycans in cancer [PATH:bta05205]
Human Diseases; Cancers; Small cell lung cancer [PATH:bta05222]
Human Diseases; Cardiovascular diseases; Hypertrophic cardiomyopathy (HCM) [PATH:bta05410]
Human Diseases; Cardiovascular diseases; Arrhythmogenic right ventricular cardiomyopathy (ARVC) [PATH:bta05412]
Human Diseases; Cardiovascular diseases; Dilated cardiomyopathy (DCM) [PATH:bta05414]

SSDB

Motif

Pfam:

Integrin_alpha2 VWA FG-GAP VWA_2 FG-GAP_2 VCBS Integrin_alpha Fn3_assoc

Other DBs

NCBI-GI:

NCBI-GeneID:

BGD-bta:

Ensembl:

UniProt:

Position

AA seq 1179 aa
MRPGRTGGTPLQLVLVFSQGILNCCVAYNVGLPKAKIFSGPSSEQFGYAVQQFINPKGNW
LLVGSPWSGFPKNRMGDVYKCPVDLSTTTCEKLNLQTSTSMSNVTEMKTNMSLGLTLTRN
VGTGGFLTCGPLWAQQCGSQYYTTGVCSDVSPDFQLRTSFAPAVQTCPSFIDVVVVCDES
NSIYPWDAVKNFLEKFVQGLDIGPTKTQMGLIQYANNPRVVFNLNTFKSKDEMIKATSQT
FQYGGDLTNTFKAIQYARDTAYSTAAGGRPGATKVMVVVTDGESHDGSKLKAVIDQCNKD
NILRFGIAVLGYLNRNALDTKNLIKEIKAIASIPTERHFFNVSDEADLLEKAGTIGEQIF
SIEGTVQGGDNFQMEMSQVGFSAEYSPQNNILMLGAVGAYDWSGTVVQKTPHGHLIFSKQ
AFEQILQDRNHSSYLGYSVASISTGNSVHFVAGAPRANYTGQIVLYSVNENGNVTVIQSH
RGDQIGSYFGSVLCAVDVNKDTITDVLLVGAPMYMNDLKKEEGRVYLFTITKGILNWHQF
LEGPKGLENARFGSAIAALSDINMDGFNDVIVGSPLENQNSGAVYIYNGHEGMIRLRYSQ
KILGSDRAFSSHLQYFGRSLDGYGDLNGDSITDVSVGAFGQVVQLWSQSIADVSVDASFT
PKKITLLNKNAEIKLKLCFSAKFRPTNQNNQVAIVYNITIDEDQFSSRVISRGLFKENNE
RCLQKTMIVSQAQRCSEYIIHIQEPSDIISPLNLCMNISLENPGTNPALEAYSETVKVFS
IPFHKDCGDDGVCISDLVLNVQQLPATQQQPFIVSNQNKRLTFSVQLKNKKESAYNTEIV
VDFSENLFFASWSMPVDGTEVTCQIASSQKSVTCNVGYPALKSKQQVTFTINFDFNLQNL
QNQASISFRALSESQEENMADNSVNLKLSLLYDAEIHITRSTNINFYEVSLDGNVSSVVH
SFEDIGPKFIFSIKVTTGSVPVSMASVIIHIPQYTKDKNPLMYLTGVHTDQAGDISCEAE
INPLKIGQTSSSVSFKSENFRHIKELNCRTASCSNIMCWLRDLQVKGEYFLNVSTRIWNG
TFAASTFQTVQLTAAAEIDTYNPQIYVIEENTVTIPLTIMKPHEKVEVPTGVIVGSVIAG
ILLLLALVAILWKLGFFKRKYEKMAKNPDETDETTELNS

NT seq 3540 nt +upstreamnt +downstreamnt
atgcggccaggacggacaggcggcacgccgctgcagctggtgttagtgttcagtcaaggc
attttaaactgttgtgtggcatacaacgttggtctcccaaaagcaaagatattttctggt
ccttcaagtgaacagtttggctatgcagtgcagcagtttataaatccaaaaggcaactgg
ttactggttggttcaccatggagtggctttcctaagaaccgaatgggagatgtatataaa
tgtcctgttgatctatccaccactacatgtgaaaaattgaatttgcaaacttccacgagc
atgtccaatgttactgagatgaaaaccaacatgagccttggcttgacactgacaaggaac
gtgggaacaggaggatttcttacctgtggtcccctgtgggcacagcagtgtggaagtcag
tattacacaactggcgtttgctctgatgtcagtcctgattttcagttgcggaccagcttt
gcgcctgcagttcagacctgcccttccttcatagatgttgtggttgtatgtgatgaatca
aacagtatttatccctgggatgcagtaaagaactttttggaaaaatttgtacaaggccta
gatataggccccacaaagacacagatggggttaattcaatatgccaataatccaagagtt
gtgtttaacctgaatacttttaaatccaaagatgaaatgattaaagcaacatcgcagaca
ttccaatatggtggagaccttacaaataccttcaaagcaattcagtatgcaagagatacc
gcttattcaacggctgctggtggacgaccaggtgctaccaaagttatggtggttgtaact
gatggtgaatcccatgatggttcaaagttgaaagctgtgattgatcaatgtaacaaagac
aatatactgaggtttggcatagcagttcttgggtacttaaacagaaacgccctggatact
aaaaatttaataaaggaaattaaagctattgccagtattccaacagaaagacactttttc
aatgtctctgatgaagcagatctactagaaaaggctgggacaataggagaacaaattttc
agcattgaaggtacagttcaaggaggagacaacttccaaatggaaatgtcgcaagtggga
ttcagcgcggaatactctcctcaaaataatattctgatgctgggtgcagtaggagcttac
gactggagtgggactgtggtgcagaagacacctcatggacatttgatcttttctaaacaa
gcgtttgaacaaattctgcaagacagaaatcacagttcatatttaggttactctgtggct
tcaatttctactgggaacagtgtccactttgttgctggtgctcctcgagcaaattatact
ggccagatagtgctctacagtgttaatgagaatggcaatgtcacagttattcagtctcac
agaggtgaccagattggctcctattttggtagtgtgctgtgtgcagtcgatgtgaataag
gacaccattacagatgtgctcttggtaggtgcaccaatgtacatgaatgacctaaagaaa
gaggaaggaagagtctacctgtttactattacaaagggcattttgaattggcaccaattt
ctggaaggccccaagggtcttgaaaatgctcgatttggttcagcaattgcagctctttca
gacatcaacatggatggctttaatgacgtgattgttggttcgcctttggaaaatcagaac
tctggagctgtgtacatctacaatggtcatgagggcatgattcgcttgaggtattctcag
aaaatcctggggtccgacagagcctttagtagccacctccagtactttgggagatccctg
gatggctatggagatttaaatggggattccatcaccgacgtgtccgtgggggcctttgga
caggtcgttcagctctggtcacagagcattgctgatgtatctgtagatgcttcattcaca
ccaaaaaaaatcactttgctcaacaaaaatgctgagataaaacttaaactctgcttcagt
gctaagtttagacctactaatcaaaacaatcaagtggccattgtgtataacatcacaatt
gatgaagaccagttttcatccagagtgatatccagggggttatttaaggaaaataatgaa
aggtgcttgcagaagaccatgatagtaagtcaagcacagcgctgttctgagtacatcatc
cacatacaggagccctctgacattatcagccctctgaatctgtgtatgaacattagtctg
gaaaaccctggcactaaccctgcccttgaagcctactctgagacggtcaaggtcttcagt
atccctttccataaagactgtggtgatgatggagtttgcatttctgatctagttctaaat
gttcagcagctgccagccactcaacaacagcccttcattgtcagcaaccaaaacaaaagg
ttaacattttcagtacaactgaaaaacaagaaggaaagtgcctacaacactgagattgtt
gttgatttttcagaaaacctgttttttgcttcctggtccatgccggttgatgggacagaa
gtgacctgccagattgcttcatctcagaagtctgttacctgcaatgtgggctaccctgct
ttaaagagcaaacaacaggtgactttcactattaacttcgacttcaatcttcaaaacctt
cagaatcaggcatctatcagtttccgagccttaagcgaaagccaggaagaaaacatggca
gataattcagtcaacttaaaactctctctgctgtatgatgccgaaattcacataacaaga
tctaccaacataaatttttatgaagtctccttggatgggaatgtttcttctgtcgtgcac
agttttgaagatattggtccaaaattcatcttctccattaaggtaacaacaggaagtgtt
ccagtaagcatggcatctgtgatcatccacatccctcaatacaccaaagacaagaaccca
ctgatgtacctgaccggggtgcacacagatcaggctggtgacatcagttgcgaagccgaa
ataaatccactgaaaataggacagacgtcttcttctgtatctttcaagagtgaaaatttc
cggcacataaaagaattgaactgtagaaccgcttcatgcagtaacatcatgtgctggctg
agagaccttcaggtgaaaggagaatacttccttaatgtgtccaccaggatttggaatggg
actttcgcagcatcgactttccagacagtacagttgacagcagctgcagaaattgacaca
tataaccctcagatatacgtgatcgaagaaaacacggtgacgattccccttacgataatg
aaaccccatgagaaagttgaagtaccgactggagtgatagtaggaagtgtaatcgctgga
atccttttgctattagctctagttgcaattttatggaagcttggattcttcaaaagaaaa
tatgaaaaaatggccaaaaatccagatgaaaccgatgagaccacagaactcaacagctga

All links

Pathway (12)   
   KEGG PATHWAY (12)   
Genome (1)   
   KEGG GENOME (1)   
Gene (8)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (2)   
   UniGene (1)   
   BGD-BTA (1)   
   ENSEMBL-BTA (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (3)   
   RefSeq(nuc) (1)   
   GenBank (1)   
   EMBL (1)   
Protein domain (8)   
   Pfam (8)   
All databases (34)   

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