KEGG   Bos taurus (cow): 281987Help
Entry
281987            CDS       T01008                                 

Gene name
PLCG1
Definition
phospholipase C, gamma 1 (EC:3.1.4.11)
Orthology
K01116  
phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
Organism
bta  Bos taurus (cow)
Pathway
Inositol phosphate metabolism
Metabolic pathways
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Calcium signaling pathway
NF-kappa B signaling pathway
HIF-1 signaling pathway
Phosphatidylinositol signaling system
VEGF signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Inflammatory mediator regulation of TRP channels
Thyroid hormone signaling pathway
Epstein-Barr virus infection
Pathways in cancer
Proteoglycans in cancer
MicroRNAs in cancer
Glioma
Non-small cell lung cancer
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Class
Metabolism; Carbohydrate metabolism; Inositol phosphate metabolism [PATH:bta00562]
Environmental Information Processing; Signal transduction; Ras signaling pathway [PATH:bta04014]
Environmental Information Processing; Signal transduction; Rap1 signaling pathway [PATH:bta04015]
Environmental Information Processing; Signal transduction; ErbB signaling pathway [PATH:bta04012]
Environmental Information Processing; Signal transduction; VEGF signaling pathway [PATH:bta04370]
Environmental Information Processing; Signal transduction; NF-kappa B signaling pathway [PATH:bta04064]
Environmental Information Processing; Signal transduction; HIF-1 signaling pathway [PATH:bta04066]
Environmental Information Processing; Signal transduction; Calcium signaling pathway [PATH:bta04020]
Environmental Information Processing; Signal transduction; Phosphatidylinositol signaling system [PATH:bta04070]
Organismal Systems; Immune system; Natural killer cell mediated cytotoxicity [PATH:bta04650]
Organismal Systems; Immune system; T cell receptor signaling pathway [PATH:bta04660]
Organismal Systems; Immune system; Fc epsilon RI signaling pathway [PATH:bta04664]
Organismal Systems; Immune system; Fc gamma R-mediated phagocytosis [PATH:bta04666]
Organismal Systems; Immune system; Leukocyte transendothelial migration [PATH:bta04670]
Organismal Systems; Endocrine system; Thyroid hormone signaling pathway [PATH:bta04919]
Organismal Systems; Nervous system; Neurotrophin signaling pathway [PATH:bta04722]
Organismal Systems; Sensory system; Inflammatory mediator regulation of TRP channels [PATH:bta04750]
Human Diseases; Cancers; Pathways in cancer [PATH:bta05200]
Human Diseases; Cancers; MicroRNAs in cancer [PATH:bta05206]
Human Diseases; Cancers; Proteoglycans in cancer [PATH:bta05205]
Human Diseases; Cancers; Glioma [PATH:bta05214]
Human Diseases; Cancers; Non-small cell lung cancer [PATH:bta05223]
Human Diseases; Infectious diseases; Epstein-Barr virus infection [PATH:bta05169]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
BGD-bta: 
Ensembl: 
UniProt: 
Structure
PDB: 

Jmol
Position
13
AA seq 1291 aa AA seqDB search
MAGAASPCANGCGPSAPSDAEVVHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQI
TWSRGADKIEGAIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTL
SLQATSEDEVNMWIRGLTWLMEDTLQAATPLQIERWLRKQFYSVDRNREDRISAKDLKNM
LSQVNYRVPNMRFLRERLTDLEQRTSDITYGQFAQLYRSLMYSAQKTMDLPFLEASALRA
GERPELCRVSLPEFQQFLLEYQGELWAVDRLQVQEFMLSFLRDPLREIEEPYFFLDEFVT
FLFSKENSIWNSQLDEVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMG
CRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIA
QQRNMAQYFKKVLGDTLLTKPVDIAADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTSVM
YSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEASG
STELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFW
RNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLSEPVPQT
NAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQE
GQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRNP
GFYVEANPMPTFKCAVKALFDYKAQREDELTFTKSAIIQNVEKQEGGWWRGDYGGKKQLW
FPSNYVEEMVSPAALEPEREHLDENSPLGDLLRGVLDVPACQIAVRPEGKNNRLFVFSIS
MASVAHWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKMMERRKKIALELSELVVYC
RPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDS
SNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFLAGGHCGYVLQPSVMRDEAFDPFDKS
SLRGLEPCAICIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSIKQKTEFVVDNGLNPVW
PAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEGL
ELASLLVKIDVFPAKQENGDLSPFGGASLRERSCDASGPLFHGRAREGSFEARYQQPFED
FRISQEHLADHFDGRDRRTPRRTRVNGDNRL
NT seq 3876 nt NT seq  +upstreamnt  +downstreamnt
atggcgggcgccgcgtccccctgcgccaacggctgcgggcccagtgcgccctcggacgcc
gaggtggtgcacctctgccgcagcctcgaggtgggcaccgtcatgactttgttctactcc
aagaagtcgcagcggcccgagcggaagaccttccaggtcaagctggagacgcggcagatc
acgtggagccgaggcgccgacaagatagagggggccattgacattcgtgaaatcaaggag
atccgcccagggaagacctcacgggacttcgatcgctaccaagaggatcctgcttttcga
ccggaccagtcccactgcttcgtcatcctgtatggaatggaattccgcctgaagaccctg
agcctccaagccacgtctgaggacgaagtgaacatgtggatcaggggcctgacttggctg
atggaggacacgttgcaggcagccacacccctgcagattgagaggtggctgcggaagcag
ttctactcagtggaccggaaccgtgaggaccggatatcggccaaggacctgaagaacatg
ctgtcccaggtcaactaccgggtccccaacatgcgcttcctccgggagcggctgacggac
ctggagcagcgcaccagtgacatcacctacgggcagtttgcacagctgtaccgcagcctc
atgtacagcgcccagaagacgatggaccttcctttcctggaagccagcgccctgagggcg
ggggagcggccggagctgtgccgggtgtcccttcctgagttccagcagttcctcctcgag
taccaaggggagctgtgggcggtggaccggctccaggtgcaggagttcatgctcagcttc
ctccgagaccccttgcgagagattgaggagccttacttcttcctggacgagttcgtcacc
ttcctgttctccaaggagaacagcatatggaactcgcagctagacgaggtgtgccccgac
accatgaacaaccccctgtcccactactggatctcctcctcgcacaacacgtacctgacc
ggggaccagttctccagcgagtcctccctggaagcctacgctcgctgcctgcggatgggc
tgccgttgcattgagttggactgctgggacggcccggatgggatgccggtcatttaccat
ggacacactctgaccaccaagatcaagttctcagacgtcctgcacaccatcaaggagcac
gcctttgtggcctcagagtacccggtcatcctgtccatcgaggaccactgcagcattgcc
cagcagaggaacatggcccagtatttcaaaaaggtgcttggggacacactcctcaccaag
cccgtggatattgcagccgacgggctcccctcccccaaccagctcaagaggaagatcctt
atcaagcacaagaagttggctgagggcagtgcctacgaggaggtgccaacatcggtgatg
tactctgagaacgacatcagcaactccatcaagaatggcatcctctacctggaagaccct
gtgaaccatgagtggtacccccactacttcgtcctgaccagcagcaagatctactactcg
gaggagaccagcagcgaccagggcaacgaggatgaggaggagcccaaggaggccagtggc
agcacagagctgcactccaacgagaagtggttccacgggaagcttggggcgggccgggat
gggcggcacatcgccgagcgcctgctcacggagtactgcattgagaccggggcccccgac
ggctccttccttgtgcgcgagagcgagacctttgtgggcgactacactctgtccttctgg
cggaatggcaaagtgcagcactgccggatccactcccggcaggacgcaggcacccccaag
ttcttcctgacggacaacctcgtcttcgactccctctatgacctcatcacgcactaccag
caggtgcccctgcgctgcaacgaatttgagatgcgcctctcagagccggtcccgcagacc
aacgcgcacgagagcaaagagtggtaccacgccagcctgaccagagcgcaggccgagcac
atgctgatgcgtgtacccagggacggggccttcctggtgcggaaacggaacgagcccaac
tcctacgccatctccttccgggctgagggcaagatcaagcactgccgcgtccagcaggag
ggccagaccgtgatgctgggcaactcagagtttgacagccttgtcgacctcatcagctac
tacgagaagcacccactgtaccgcaagatgaagctgcgctaccccatcaacgaggaggct
ctggagaagatcggcacagctgagcctgactacggcgcgctgtacgagggccgcaaccct
ggcttctatgtggaggcgaaccccatgcccacgttcaagtgcgccgtcaaagctctcttc
gactacaaagcgcagcgggaggacgagctgacattcaccaagagtgccatcatccagaac
gtggagaagcaggagggaggctggtggcggggtgactacggcgggaagaagcagctgtgg
ttcccttcaaactatgtggaggaaatggtcagcccggcggccctggagcccgagagggag
cacttggacgagaacagcccactcggggacttgctccggggggtcctggatgtgccagct
tgtcagatagccgtccgtcccgagggcaagaacaaccggctgttcgtcttctccatcagc
atggcctcggtggcacactggtccctggatgtggctgccgactcgcaggaagagctgcag
gactgggtgaagaagatccgggaggtggcgcagacagcggatgccaggctcaccgagggc
aagatgatggagcggaggaagaagatcgccctagagctctcagagctcgtcgtctactgc
cggcctgtccctttcgacgaagagaagattggcaccgaacgggcctgctaccgcgacatg
tcgtccttcccggagaccaaggccgagaagtacgtgaacaaggccaaaggcaagaagttc
ctccagtacaaccgcctgcagctctcccgcatctaccctaagggccagcggctggactcc
tccaattacgaccccctgcccatgtggatctgcggcagccagcttgtggccctcaacttc
cagaccccagacaaacccatgcagatgaaccaggccctgttcctggccggcgggcactgt
ggctatgtgctgcagcccagcgtcatgcgcgatgaggccttcgatccctttgacaagagc
agcctccgcgggctggagccgtgcgccatctgcatcgaggtgctgggggcccggcacctg
ccgaagaacggccgaggcatcgtgtgtccttttgtggagatcgaggtggccggagccgag
tatgacagcatcaagcagaagacagagtttgtggtggacaatggactgaaccccgtgtgg
ccagccaagcccttccacttccagattagtaaccccgagttcgccttcctgcgcttcgtg
gtctatgaggaggacatgtttagtgaccagaacttcctagctcaggctaccttcccagtg
aagggtctgaagacaggctacagagcggtgcctctgaagaacaactacagtgagggcctg
gagctggcctccctgctcgtcaagattgacgtgttccctgccaagcaggagaacggcgac
ctcagccccttcgggggtgcgtccctgcgggagcggagctgtgacgcctcgggcccgctg
ttccacggccgggcccgggagggctcctttgaagctcgctaccagcagccctttgaggac
ttccgcatctcccaggagcatctcgcagaccattttgacggtcgggatcgcaggacccca
cgcaggactcgggtcaacggagacaaccgcctgtag

DBGET integrated database retrieval system