KEGG   Bos taurus (cow): 282089
Entry
282089            CDS       T01008                                 
Symbol
TGFB1
Name
(RefSeq) transforming growth factor beta-1 proprotein precursor
  KO
K13375  transforming growth factor beta-1
Organism
bta  Bos taurus (cow)
Pathway
bta04010  MAPK signaling pathway
bta04060  Cytokine-cytokine receptor interaction
bta04068  FoxO signaling pathway
bta04110  Cell cycle
bta04148  Efferocytosis
bta04218  Cellular senescence
bta04350  TGF-beta signaling pathway
bta04380  Osteoclast differentiation
bta04390  Hippo signaling pathway
bta04659  Th17 cell differentiation
bta04672  Intestinal immune network for IgA production
bta04926  Relaxin signaling pathway
bta04932  Non-alcoholic fatty liver disease
bta04933  AGE-RAGE signaling pathway in diabetic complications
bta05140  Leishmaniasis
bta05142  Chagas disease
bta05144  Malaria
bta05145  Toxoplasmosis
bta05146  Amoebiasis
bta05152  Tuberculosis
bta05161  Hepatitis B
bta05166  Human T-cell leukemia virus 1 infection
bta05200  Pathways in cancer
bta05205  Proteoglycans in cancer
bta05210  Colorectal cancer
bta05211  Renal cell carcinoma
bta05212  Pancreatic cancer
bta05220  Chronic myeloid leukemia
bta05225  Hepatocellular carcinoma
bta05226  Gastric cancer
bta05321  Inflammatory bowel disease
bta05323  Rheumatoid arthritis
bta05410  Hypertrophic cardiomyopathy
bta05414  Dilated cardiomyopathy
bta05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:bta00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    282089 (TGFB1)
   04350 TGF-beta signaling pathway
    282089 (TGFB1)
   04390 Hippo signaling pathway
    282089 (TGFB1)
   04068 FoxO signaling pathway
    282089 (TGFB1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    282089 (TGFB1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    282089 (TGFB1)
  09143 Cell growth and death
   04110 Cell cycle
    282089 (TGFB1)
   04218 Cellular senescence
    282089 (TGFB1)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    282089 (TGFB1)
   04672 Intestinal immune network for IgA production
    282089 (TGFB1)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    282089 (TGFB1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    282089 (TGFB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    282089 (TGFB1)
   05205 Proteoglycans in cancer
    282089 (TGFB1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    282089 (TGFB1)
   05212 Pancreatic cancer
    282089 (TGFB1)
   05225 Hepatocellular carcinoma
    282089 (TGFB1)
   05226 Gastric cancer
    282089 (TGFB1)
   05220 Chronic myeloid leukemia
    282089 (TGFB1)
   05211 Renal cell carcinoma
    282089 (TGFB1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    282089 (TGFB1)
   05161 Hepatitis B
    282089 (TGFB1)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    282089 (TGFB1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    282089 (TGFB1)
   05144 Malaria
    282089 (TGFB1)
   05145 Toxoplasmosis
    282089 (TGFB1)
   05140 Leishmaniasis
    282089 (TGFB1)
   05142 Chagas disease
    282089 (TGFB1)
  09163 Immune disease
   05323 Rheumatoid arthritis
    282089 (TGFB1)
   05321 Inflammatory bowel disease
    282089 (TGFB1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    282089 (TGFB1)
   05414 Dilated cardiomyopathy
    282089 (TGFB1)
   05415 Diabetic cardiomyopathy
    282089 (TGFB1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    282089 (TGFB1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    282089 (TGFB1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:bta03110]
    282089 (TGFB1)
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:bta04052]
    282089 (TGFB1)
   00536 Glycosaminoglycan binding proteins [BR:bta00536]
    282089 (TGFB1)
Chaperones and folding catalysts [BR:bta03110]
 Intramolecular chaperones
  Others
   282089 (TGFB1)
Cytokines and neuropeptides [BR:bta04052]
 Cytokines
  Transforming growth factors (RSTK binding)
   282089 (TGFB1)
Glycosaminoglycan binding proteins [BR:bta00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   282089 (TGFB1)
SSDB
Motif
Pfam: TGFb_propeptide TGF_beta
Other DBs
NCBI-GeneID: 282089
NCBI-ProteinID: NP_001159540
Ensembl: ENSBTAG00000020457
VGNC: 35800
UniProt: P18341
Position
18:complement(50473691..50508349)
AA seq 390 aa
MPPSGLRLLPLLLPLLWLLMLTPGRPVAGLSTCKTIDMELVKRKRIEAIRGQILSKLRLA
SPPSQGDVPPGPLPEAILALYNSTRDRVAGESAETEPEPEADYYAKEVTRVLMVEYGNKI
YDKMKSSSHSIYMFFNTSELREAVPEPVLLSRADVRLLRLKLKVEQHVELYQKYSNNSWR
YLSNRLLAPSDSPEWLSFDVTGVVRQWLTRREEIEGFRLSAHCSCDSKDNTLQVDINGFS
SGRRGDLATIHGMNRPFLLLMATPLERAQHLHSSRHRRALDTNYCFSSTEKNCCVRQLYI
DFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQA
LEPLPIVYYVGRKPKVEQLSNMIVRSCKCS
NT seq 1173 nt   +upstreamnt  +downstreamnt
atgccgccctcggggctgcggctgctgccgctgctgctgccgctgctgtggctgctaatg
ctgacgcctggccggccggtcgccggactgtccacctgcaagaccatcgacatggagctg
gtgaagcggaagcgcatcgaggccatccgcggccagattttgtccaagcttcggctcgcc
agccccccgagccagggggatgtgccacccggcccgctgcccgaggccatactggccctt
tacaacagtacccgcgaccgggtggccggggaaagtgccgaaacggagcctgagccagag
gcggactactacgccaaggaggtcacccgcgtgctaatggtggaatacggcaacaaaatc
tatgacaaaatgaagtctagctcgcacagcatatatatgttcttcaacacgtccgagctc
cgggaagcggtgcccgaacctgtgttgctctctcgggcagacgtgcgcctgctgaggctc
aagttaaaagtggagcagcacgtggagctgtaccagaaatatagcaacaattcctggcgc
tacctcagcaaccggctgctcgcccccagcgactcaccggagtggctgtcctttgacgtc
actggagttgtgcggcagtggctgacccgcagagaggaaatagagggctttcgcctcagt
gcccactgttcctgtgacagtaaagataacacgcttcaagtggacattaacgggttcagt
tccggccgccggggtgacctcgccaccattcacggcatgaaccggcccttcctgctcctc
atggccacccctctggagagggcccagcacctgcacagctcccgccaccgccgagccctg
gacaccaactactgcttcagctccacagaaaagaactgctgtgttcgtcagctctacatt
gacttccggaaggacctgggctggaagtggattcatgaacccaaggggtaccacgccaat
ttctgcctggggccctgcccttacatctggagcctggatacacagtacagcaaggtcctg
gccctgtacaaccagcacaacccgggcgcttcggcggcgccgtgctgcgtgcctcaggcg
ctggagcccctgcccatcgtgtactacgtgggccgcaagcccaaggtggagcagttgtcc
aacatgatcgtgcgctcctgcaagtgcagctga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (35)   
   KEGG PATHWAY (35)   
Genome (1)   
   KEGG GENOME (1)   
Gene (8)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (11)   
   RefSeq(nuc) (5)   
   GenBank (3)   
   EMBL (3)   
Protein domain (2)   
   Pfam (2)   
All databases (68)   

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