KEGG   Bos taurus (cow): 282213Help
Entry
282213            CDS       T01008                                 

Gene name
CYP2E1
Definition
cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7)
Orthology
K07415  
cytochrome P450, family 2, subfamily E, polypeptide 1 [EC:1.14.13.-]
Organism
bta  Bos taurus (cow)
Pathway
Steroid hormone biosynthesis
Arachidonic acid metabolism
Linoleic acid metabolism
Metabolism of xenobiotics by cytochrome P450
Drug metabolism - cytochrome P450
Metabolic pathways
Non-alcoholic fatty liver disease (NAFLD)
Chemical carcinogenesis
Brite
KEGG Orthology (KO) [BR:bta00001]
 Metabolism
  Lipid metabolism
   00140 Steroid hormone biosynthesis
    282213 (CYP2E1)
   00590 Arachidonic acid metabolism
    282213 (CYP2E1)
   00591 Linoleic acid metabolism
    282213 (CYP2E1)
  Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    282213 (CYP2E1)
   00982 Drug metabolism - cytochrome P450
    282213 (CYP2E1)
 Human Diseases
  Cancers
   05204 Chemical carcinogenesis
    282213 (CYP2E1)
  Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    282213 (CYP2E1)
Enzymes [BR:bta01000]
 1. Oxidoreductases
  1.14  Acting on paired donors with incorporation of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.-  
     282213 (CYP2E1)
Cytochrome P450 [BR:bta00199]
 Cytochrome P450, animal type
  CYP2 family
   282213 (CYP2E1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
BGD-bta: 
Ensembl: 
UniProt: 
Position
26
AA seq 495 aa AA seqDB search
MAALGITVALLVWMATLLFISIWKHIYSSWKLPPGPFPLPIIGNLLQLDIKNIPKSFTRL
AERYGPVFTLYLGSQRAVVVHGYKPVKEVLLDYKNEFSGRGENPGFQMHKNNGIIFNNGS
TWRDTRRFSLTTLRDLGMGKQGNEQRIQREAHFLLEVLRKTQGQPFDPTFVVGFAPYNVI
SDILFHKRFDYKDQTSLRLMSLFNENFYLLSSPWIQLYNNFSDYLQYLPGSHRKLLKNVS
EVKSYALERVKDHQKSLEPSCPRGFLDTMLIEMAKERHSVDPMYTLENIAVTVADLLFAG
TETTSTTLRYGLLILMKYPEVEEKLHEEIDRVIGPSRIPAVKDRLDMPYLDAVVHEIQRF
IDLLPSNLLHEATQDTVFRGYVIPKGTVVIPTLDSVLHDRQEFPEPEKFKPEHFLNENGK
FKYSDHFKAFSAGKRVCVGEGLARMELFLLLAAILQHFNLKSLVDPKDIDLSPIAIGFGK
IPPRYKLCLIPRSKV
NT seq 1488 nt NT seq  +upstreamnt  +downstreamnt
atggccgccctgggcatcacggtcgccctgctggtgtggatggccaccctgctgttcatc
tccatctggaagcacatctacagcagctggaaactgccccctggccctttcccactgccc
atcatcgggaatcttttacagctggatattaagaacattcccaaatccttcaccaggctg
gcggagaggtacgggccggtgttcaccctgtacctgggctctcagcgtgccgtggtcgtg
catggctacaagcccgtgaaggaggtcctccttgactacaagaacgagttttctggcaga
ggagaaaaccctgggttccagatgcacaagaacaatgggatcattttcaacaatggatca
acctggcgggacacccgacggttctcgttgaccaccctccgtgacttagggatgggaaaa
cagggcaatgagcagcggatccagagggaggcccacttcctgctggaggtgctcaggaag
acccagggccagccctttgaccccacgtttgtcgtcggctttgcaccttacaatgtcatc
tctgacatcctcttccacaaacgctttgactataaagatcagacgagcctgaggctgatg
agtctgttcaacgagaacttctacctgctcagcagcccctggatccagctttataataat
ttctcagactacctacagtacctgcctggaagccatagaaagctactgaaaaatgtgtct
gaagtaaaaagttatgctttagaaagagtgaaggatcaccagaagtccctggaacccagc
tgcccccgaggcttcttggacaccatgctgatagaaatggccaaggaaagacacagtgtg
gaccctatgtacaccttggaaaacatcgctgtgactgtggccgacctgctctttgcgggg
acagagaccaccagcaccaccctgcgatacgggctcctgattctcatgaaatacccggag
gttgaagagaaacttcatgaagaaattgacagggtgattgggccaagccgaatccctgcc
gtcaaggacaggctggacatgccctacctggatgctgtggtacatgagattcagcgattc
atcgacctccttccctccaatctgctccacgaagcaacccaggacacagtgttcagagga
tatgtcatccccaagggcacagtcgtaattccgacgctggactctgtcttacacgatagg
caagagtttcctgaaccagagaagtttaaaccagagcactttctgaatgaaaatggaaag
ttcaagtacagtgaccattttaaggcgttttctgcaggaaagcgggtgtgtgttggagaa
ggcctggctcgcatggaactgttcctgctcttggccgccatcctgcagcactttaacttg
aagtcacttgttgaccccaaggatatcgacctcagccccattgcaattgggtttggcaag
atcccgccccgttacaaactctgtctcattccccgctcaaaagtgtga

DBGET integrated database retrieval system