KEGG   Bos taurus (cow): 282388
Entry
282388            CDS       T01008                                 
Symbol
TXNRD1
Name
(RefSeq) thioredoxin reductase 1, cytoplasmic
  KO
K22182  thioredoxin reductase (NADPH) [EC:1.8.1.9]
Organism
bta  Bos taurus (cow)
Pathway
bta00450  Selenocompound metabolism
bta05200  Pathways in cancer
bta05225  Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:bta00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    282388 (TXNRD1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    282388 (TXNRD1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    282388 (TXNRD1)
Enzymes [BR:bta01000]
 1. Oxidoreductases
  1.8  Acting on a sulfur group of donors
   1.8.1  With NAD+ or NADP+ as acceptor
    1.8.1.9  thioredoxin-disulfide reductase
     282388 (TXNRD1)
SSDB
Motif
Pfam: Pyr_redox_2 Pyr_redox_dim Pyr_redox Pyr_redox_3 FAD_binding_2 HI0933_like Thi4 AlaDh_PNT_C FAD_oxidored NAD_binding_8 GIDA DAO Lycopene_cycl
Other DBs
NCBI-GeneID: 282388
NCBI-ProteinID: NP_777050
Ensembl: ENSBTAG00000013912
VGNC: 36545
UniProt: O62768
Position
5:67898938..67961974
AA seq 499 aa
MNGSKDLPEPYDYDLIIIGGGSGGLAAAKEAAKYDKKVMVLDFVTPTPLGTRWGLGGTCV
NVGCIPKKLMHQAALLGQALRDSRNYGWNVEETVKHDWERMTEAVQNHIGSLNWGYRVAL
REKKVTYENAYGEFVGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISS
DDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHM
QEHGIKFIRQFVPIKVEQIEAGTPGRLRVIAKSTDSDQTIEGEYNTVLLAIGRDACTRKI
GLENVGVKINEKTGKIPVTEEEQTNVPYIYAIGDILEGKLELTPVAIQAGRLLAQRLYGG
STVKCDYENVPTTVFTPLEYGSCGLSEEKAVEKFGEENVEVYHSYFWPLEWTIPSRDNNK
CYAKVVCNIKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKDQLDSTIGIHPVCAEVFT
TLSVTKRSGGNILQTGCUG
NT seq 1500 nt   +upstreamnt  +downstreamnt
atgaatggctccaaggatctcccggagccctatgactacgacctcatcatcattggaggg
ggttctggaggactggcagccgccaaggaggcagccaaatatgacaagaaggtgatggtt
ctggattttgtcactccaacccctcttggaactagatggggtcttggaggaacgtgtgtg
aatgtgggttgcatacctaaaaaattgatgcaccaagcagcgttgttaggtcaagcccta
cgagactctcgaaactatgggtggaacgtcgaggagacagttaaacatgactgggagcga
atgacagaggcggtccagaaccacattggttctctcaactggggctaccgcgtggctctg
cgggagaaaaaggtcacctatgagaacgcatacggagagtttgtggggcctcataggatt
aaggcaacaaataacaaaggcaaagagaagatttactcagcagagagatttctcattgcc
actggtgaaaggccgcgttatttgggtatccccggtgacaaagaatactgtatcagcagt
gatgatcttttctctctaccttattgcccgggtaagaccctggtggttggagcatcctat
gttgctttggaatgtgctggatttcttgctggtattggtttagacgtcactgttatggta
cgatccattctcctaagaggatttgaccaggacatggccaacaaaattggtgaacatatg
caagaacatggtatcaagttcataagacagtttgtaccaataaaagttgaacaaattgaa
gcagggacaccaggccgactgagagtgatagctaagtccaccgatagtgaccaaaccatc
gaaggagagtataatacggtattgctggcaataggaagagatgcttgcacgagaaaaatt
ggcttagaaaacgtgggggtaaagataaatgaaaagactggaaaaatacctgtcacagag
gaagagcaaaccaacgtgccttacatctatgccatcggtgatatattggaagggaagctg
gagctcacccccgtggccatccaggcaggaaggctgctggctcagaggctgtatggtggc
tccactgttaagtgtgactatgaaaacgttccaacgactgttttcactcctttggaatat
gggtcttgtggtctttctgaggagaaagctgtggagaaatttggggaagaaaatgttgag
gtttaccatagttacttttggccattggaatggacgattccatcaagggataacaacaaa
tgttacgcaaaagtagtctgcaatatcaaagacaatgaacgtgttgtgggcttccacgta
ctgggtccaaatgctggagaagtgacccagggcttcgcagcggcgctcaaatgtgggctg
accaaagaccagctggacagcaccatcggaatccaccccgtttgcgcagaggtgttcacg
actctgtcggtgaccaagcgctccgggggaaacatcctccagaccggttgctgaggttaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (13)   
   RefSeq(nuc) (1)   
   GenBank (6)   
   EMBL (6)   
Protein domain (13)   
   Pfam (13)   
All databases (59)   

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