KEGG   Bos taurus (cow): 504531Help
Entry
504531            CDS       T01008                                 

Gene name
PIK3CD
Definition
phosphoinositide-3-kinase, catalytic, delta polypeptide (EC:2.7.1.153)
Orthology
K00922  
phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
Organism
bta  Bos taurus (cow)
Pathway
Inositol phosphate metabolism
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phosphatidylinositol signaling system
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Apoptosis
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Osteoclast differentiation
Focal adhesion
Platelet activation
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Cholinergic synapse
Inflammatory mediator regulation of TRP channels
Regulation of actin cytoskeleton
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Prolactin signaling pathway
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Type II diabetes mellitus
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Carbohydrate digestion and absorption
Bacterial invasion of epithelial cells
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Amoebiasis
Hepatitis C
Hepatitis B
Measles
Influenza A
HTLV-I infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Colorectal cancer
Renal cell carcinoma
Pancreatic cancer
Endometrial cancer
Glioma
Prostate cancer
Melanoma
Chronic myeloid leukemia
Acute myeloid leukemia
Small cell lung cancer
Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:bta00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    504531 (PIK3CD)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    504531 (PIK3CD)
   04015 Rap1 signaling pathway
    504531 (PIK3CD)
   04012 ErbB signaling pathway
    504531 (PIK3CD)
   04370 VEGF signaling pathway
    504531 (PIK3CD)
   04630 Jak-STAT signaling pathway
    504531 (PIK3CD)
   04668 TNF signaling pathway
    504531 (PIK3CD)
   04066 HIF-1 signaling pathway
    504531 (PIK3CD)
   04068 FoxO signaling pathway
    504531 (PIK3CD)
   04070 Phosphatidylinositol signaling system
    504531 (PIK3CD)
   04024 cAMP signaling pathway
    504531 (PIK3CD)
   04022 cGMP - PKG signaling pathway
    504531 (PIK3CD)
   04151 PI3K-Akt signaling pathway
    504531 (PIK3CD)
   04152 AMPK signaling pathway
    504531 (PIK3CD)
   04150 mTOR signaling pathway
    504531 (PIK3CD)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    504531 (PIK3CD)
  Cell growth and death
   04210 Apoptosis
    504531 (PIK3CD)
  Cellular commiunity
   04510 Focal adhesion
    504531 (PIK3CD)
 Organismal Systems
  Immune system
   04611 Platelet activation
    504531 (PIK3CD)
   04620 Toll-like receptor signaling pathway
    504531 (PIK3CD)
   04650 Natural killer cell mediated cytotoxicity
    504531 (PIK3CD)
   04660 T cell receptor signaling pathway
    504531 (PIK3CD)
   04662 B cell receptor signaling pathway
    504531 (PIK3CD)
   04664 Fc epsilon RI signaling pathway
    504531 (PIK3CD)
   04666 Fc gamma R-mediated phagocytosis
    504531 (PIK3CD)
   04670 Leukocyte transendothelial migration
    504531 (PIK3CD)
   04062 Chemokine signaling pathway
    504531 (PIK3CD)
  Endocrine system
   04910 Insulin signaling pathway
    504531 (PIK3CD)
   04915 Estrogen signaling pathway
    504531 (PIK3CD)
   04914 Progesterone-mediated oocyte maturation
    504531 (PIK3CD)
   04917 Prolactin signaling pathway
    504531 (PIK3CD)
   04921 Oxytocin signaling pathway
    504531 (PIK3CD)
   04919 Thyroid hormone signaling pathway
    504531 (PIK3CD)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    504531 (PIK3CD)
  Digestive system
   04973 Carbohydrate digestion and absorption
    504531 (PIK3CD)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    504531 (PIK3CD)
  Nervous system
   04725 Cholinergic synapse
    504531 (PIK3CD)
   04722 Neurotrophin signaling pathway
    504531 (PIK3CD)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    504531 (PIK3CD)
  Development
   04380 Osteoclast differentiation
    504531 (PIK3CD)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    504531 (PIK3CD)
   05205 Proteoglycans in cancer
    504531 (PIK3CD)
   05203 Viral carcinogenesis
    504531 (PIK3CD)
   05210 Colorectal cancer
    504531 (PIK3CD)
   05212 Pancreatic cancer
    504531 (PIK3CD)
   05214 Glioma
    504531 (PIK3CD)
   05221 Acute myeloid leukemia
    504531 (PIK3CD)
   05220 Chronic myeloid leukemia
    504531 (PIK3CD)
   05218 Melanoma
    504531 (PIK3CD)
   05211 Renal cell carcinoma
    504531 (PIK3CD)
   05215 Prostate cancer
    504531 (PIK3CD)
   05213 Endometrial cancer
    504531 (PIK3CD)
   05222 Small cell lung cancer
    504531 (PIK3CD)
   05223 Non-small cell lung cancer
    504531 (PIK3CD)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    504531 (PIK3CD)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    504531 (PIK3CD)
  Infectious diseases
   05100 Bacterial invasion of epithelial cells
    504531 (PIK3CD)
   05166 HTLV-I infection
    504531 (PIK3CD)
   05162 Measles
    504531 (PIK3CD)
   05164 Influenza A
    504531 (PIK3CD)
   05161 Hepatitis B
    504531 (PIK3CD)
   05160 Hepatitis C
    504531 (PIK3CD)
   05169 Epstein-Barr virus infection
    504531 (PIK3CD)
   05146 Amoebiasis
    504531 (PIK3CD)
   05145 Toxoplasmosis
    504531 (PIK3CD)
   05142 Chagas disease (American trypanosomiasis)
    504531 (PIK3CD)
Enzymes [BR:bta01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     504531 (PIK3CD)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
BGD-bta: 
Ensembl: 
Position
16
AA seq 1044 aa AA seqDB search
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKPLILTLTWLP
RLSGLHEFDSLQDPEVNDFRGKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRVLLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFYIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGEHCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAP
HPVYYPFLDKILELGRLGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEIQE
HFPEALARLLLVTKWNKHEDVAQMLYLLSSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRRIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDVVKVSSQKTTKPQTKELMHLCMR
QETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGTVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
NT seq 3135 nt NT seq  +upstreamnt  +downstreamnt
atgccccccggggttgactgccccatggaattctggaccaaggaggagaatcagaacgtg
gcagttgatttcttgctccccacgggggtctatctgaacttccctgtgtcccgaaatgcc
aacctcagcactatcaagaaggtgttatggcaccgagcccagtacgagccgctcttccac
atgctcagtgaccctgaggcctacgtgttcacctgcgtcaaccagacggcggagcagcag
gagctggaggacgagcagcggcggctctgcgacatccagcccttcctgcccgtcctgcgg
ctggtggcccgcgagggtgaccgcgtgaagcccctgatcctgacgctgacctggctccct
cgcctctcaggcctccacgagtttgactccttgcaagacccggaggtgaatgacttccga
ggcaagatgcgccagttctgcgaggaggcggctgcccgcaggcagcagctgggctgggag
gcctggctgcagtacagcttccctctgcagttggagccctcggcgcggagctgggggcca
ggcaccctgcgcgtccccaatcgggtcctcctggtcaatgtcaagtttgagggcagcgag
gagagcttcaccttccaggtatccaccaaggatgtgcccctggcactgatggcctgtgcc
ctccgaaagaaggccacggtgttccggcagccgctggtggagcagcctgaggactacacg
ctgcaggtgaacggcaagcacgagtacctgtacggcagctaccccctctgccagttccag
tacatctgcagctgcctgcacagtgggctgaccccgcacctgaccatggtgcactcctcc
tccattctcgccatgcgggacgagcagagcaaccctgccccccaagtccagaagccacgc
accaaaccaccccccatccccatgaagaagccctcctctgtgtccctctggtccctggag
cagcctttctacatcgagctgatccagggcagcaaagtgaatgccgacgagcggatgaag
ctggtggtgcaggccgggctcttccatggcaatgagacgctatgcaagacggtgtccagc
tcggaggtgagcgtgtgctcggagcccgtgtggaagcagcggctggagtttgacatcaac
atctgtgacctgccccgcatggcccggctctgcttcgcgctttacgctgtgatcgagaag
gccaagaaggcccgctccaccaagaagaagtccaagaaggcggactgccccattgcctgg
gccaacctcatgctgtttgactacaaggaccagctcaagacgggcgagcactgtctctat
atgtggccctctgtcccagacgagaaaggggaactactgaacccctgtgggaccgtgcgg
agtaaccccaacactgagagtgcagccgccctggtcatctttctccctgaggtggcccct
caccctgtatactaccctttcctggacaagatcctggagctggggcggcttggagagcat
ggacgcttcacggaggaggagcagctgcagctgcgggagatcctggagcggcggggttcc
ggggaactgtacgagcacgagaaggacctagtgtggaagatgcggcacgagatccaggag
cactttcccgaggctctagcccggctgctgctggtcactaagtggaacaaacatgaggac
gtggcccagatgctctacctgctcagctcctggcctgaactgcccgttctgagcgccctg
gagttgctagacttcagcttccccgaccgccacgtgggatccttcgccatcaagtccctg
cggaaactaacggacgacgagcttttccagtacctgctgcagctggtgcaggtgctcaag
tacgagtcctacctcgactgcgagctgaccaaattcctgctggaccgggccctggccaat
cgcaggatcggccacttcctcttctggcacctccgctccgagatgcacgtgccgtcggtg
gccctgcgcttcggccttatcatggaagcctattgccggggcagcacccaccacatgaaa
gtgctgatgaagcagggggaagcactgagcaaactgaaggccctgaacgacgtcgtcaaa
gtgagctcccagaagaccaccaagccccagaccaaggagctgatgcacctgtgcatgcgc
caggagacctacctggaggccctctcccacttgcagtccccactcgaccccagcaccctg
ctggctgaagtctgcgtggagcagtgcaccttcatggactccaagatgaaacccctgtgg
gtcatgtacagcaacgaggaggcaggcagcgacggcaccgtgggcatcatctttaagaat
ggggacgacctccgccaggacatgctgaccctgcagatgatccagctcatggacattctg
tggaagcaggagggcttggacctgaggatgaccccctacggctgcctctccactggggac
cgcacaggccttatcgaggtggtgcttcactcggacaccattgccaacatccagctgaac
aagagcaacatggcggccacggctgccttcaataaggatgctctgctcaactggctcaag
tccaagaaccctggggaggccctggatcgagccattgaggagttcaccctctcctgtgct
ggctactgtgtggctacctatgtgctgggcattggcgatcgtcacagcgacaacatcatg
atccgagagaacgggcagctgttccacattgatttcggccactttctggggaatttcaag
accaagtttggaatcaaccgtgagcgggtcccgttcatcctcacctatgactttgtccac
gtgatccagcaagggaagacgaataatagtgagaagtttgaaaggttccggggctactgt
gagagggcctacaccatcctgcggcgccatgggctccttttcctccacctctttgccctg
atgcgggcggcaggcctgcctgagctcagctgctccaaagacatccagtatctcaaggat
tctctggcattggggaaaacggaggaggaggctctgaagcacttccgagtgaagtttaat
gaagccctccgggaaagctggaaaaccaaagtgaactggctggcccacaacgtgtccaaa
gataacaggcaataa

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