KEGG   Bos taurus (cow): 508888Help
Entry
508888            CDS       T01008                                 

Gene name
PLCB2
Definition
phospholipase C, beta 2
Orthology
K05858  
phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
bta  Bos taurus (cow)
Pathway
Inositol phosphate metabolism
Metabolic pathways
Rap1 signaling pathway
Calcium signaling pathway
Chemokine signaling pathway
Phosphatidylinositol signaling system
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Wnt signaling pathway
Gap junction
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
Dopaminergic synapse
Long-term depression
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Endocrine and other factor-regulated calcium reabsorption
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Alzheimer's disease
Huntington's disease
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Amoebiasis
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Class
Metabolism; Carbohydrate metabolism; Inositol phosphate metabolism [PATH:bta00562]
Environmental Information Processing; Signal transduction; Rap1 signaling pathway [PATH:bta04015]
Environmental Information Processing; Signal transduction; Wnt signaling pathway [PATH:bta04310]
Environmental Information Processing; Signal transduction; Calcium signaling pathway [PATH:bta04020]
Environmental Information Processing; Signal transduction; Phosphatidylinositol signaling system [PATH:bta04070]
Cellular Processes; Cell communication; Gap junction [PATH:bta04540]
Organismal Systems; Immune system; Chemokine signaling pathway [PATH:bta04062]
Organismal Systems; Endocrine system; Insulin secretion [PATH:bta04911]
Organismal Systems; Endocrine system; GnRH signaling pathway [PATH:bta04912]
Organismal Systems; Endocrine system; Estrogen signaling pathway [PATH:bta04915]
Organismal Systems; Endocrine system; Oxytocin signaling pathway [PATH:bta04921]
Organismal Systems; Endocrine system; Thyroid hormone synthesis [PATH:bta04918]
Organismal Systems; Endocrine system; Thyroid hormone signaling pathway [PATH:bta04919]
Organismal Systems; Endocrine system; Melanogenesis [PATH:bta04916]
Organismal Systems; Circulatory system; Adrenergic signaling in cardiomyocytes [PATH:bta04261]
Organismal Systems; Circulatory system; Vascular smooth muscle contraction [PATH:bta04270]
Organismal Systems; Digestive system; Salivary secretion [PATH:bta04970]
Organismal Systems; Digestive system; Gastric acid secretion [PATH:bta04971]
Organismal Systems; Digestive system; Pancreatic secretion [PATH:bta04972]
Organismal Systems; Excretory system; Endocrine and other factor-regulated calcium reabsorption [PATH:bta04961]
Organismal Systems; Nervous system; Glutamatergic synapse [PATH:bta04724]
Organismal Systems; Nervous system; Cholinergic synapse [PATH:bta04725]
Organismal Systems; Nervous system; Dopaminergic synapse [PATH:bta04728]
Organismal Systems; Nervous system; Serotonergic synapse [PATH:bta04726]
Organismal Systems; Nervous system; Long-term potentiation [PATH:bta04720]
Organismal Systems; Nervous system; Long-term depression [PATH:bta04730]
Organismal Systems; Nervous system; Retrograde endocannabinoid signaling [PATH:bta04723]
Organismal Systems; Sensory system; Inflammatory mediator regulation of TRP channels [PATH:bta04750]
Organismal Systems; Environmental adaptation; Circadian entrainment [PATH:bta04713]
Human Diseases; Neurodegenerative diseases; Alzheimer's disease [PATH:bta05010]
Human Diseases; Neurodegenerative diseases; Huntington's disease [PATH:bta05016]
Human Diseases; Infectious diseases; Amoebiasis [PATH:bta05146]
Human Diseases; Infectious diseases; Chagas disease (American trypanosomiasis) [PATH:bta05142]
Human Diseases; Infectious diseases; African trypanosomiasis [PATH:bta05143]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
10
AA seq 1185 aa AA seqDB search
MSLLNPVLLPPTVKAYLSQGERFIKWDDETTIASPVILRVDPKGYYLYWTYQSKEMELLD
ITSIRDTRFGKFAKMPKSQKLREVFNMNIRDNFLLKTLTVVSGPDMVDLTFHNFVSYKDN
VGKDWAEDVLALAKHPLTANASRSTFLDKILVKLKMQLNPEGKIPVKNFFQMFPADRKRV
EAALSACHLPKGKNDAINPEDFPESVYKSFLMSLCPRPEIDEIFTSYHSKAKPYMTKEHL
AKFINQKQRDSRLNSLLFPPARPDQVQGLIDKYEPSGINVQRGQLSPEGMVWFLCGPENS
VLAQDKLLLHHDMTQPLNHYFINSSHNTYLTAGQFSGLSSAEMYRQVLLAGCRCVELDCW
KGKPPDEEPIITHGFTMTTDIYFKEAIEAIAESAFKTSPYPVILSFENHVDSPRQQAKMA
EYCRTMFGDMLLTEPLEKFPLKPGIPLPSPEDLRGKILIKNKKNQFSGSASPSKELDGEA
EGSSPPNAPVGEDTVWAGEEGAELEEEEVEEEEEESGNLDEEEIKKMQSDEGTAGLEVTA
YKEMSSLVNYIQPTKFISFEFSAQKNRSYVISSFTELKAYDLLSKSSVQFVDYNKRQMSR
IYPKGTRMDSSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMALFEFNGQSGHLLKHEFMR
RSDKQFNPFSVDRIDVVVATTLSITXISGQFLSERSVRTYVEVELFGLPGDPKRRYRTKL
SPSTNSINPVWKEEPFVFEKILMPELASLRVAVMEEGNKFLGHRIIPISALNSGYHHLCL
HNESNMPLTMPALFVFLEMKDYVPDTWADLTVALANPIKFFSAHDKKAVKLKEAMGGQSE
SPFPLGNHPASQINGASAPTSNGSAAAGAKREEATKETAEPQTASLEELRELKGVVKLQR
RQEKELRELGRRGVRRWEELLQRGAAQLAGLGPPGAGGSGGCRGRKLGPGKGSRKKRTLP
GEDTAGAASAEGPEGEDVRLRELRDRLELELLQLGEEQCECVMKLKEQHAAQQMTKMMEL
AREKQAAERKTLKETLEIDTKEMKKKLEAKRLERIQAMMKVTTDKMAQERLKREINNSHI
QEVVQVIKQMTENLERHQEKLEEKQAACLEQIQEMEKQFQQEAMAEYEAKMKGLEMEVKE
SVRTCLRACFPSEEEDKPERPCVVSRELCEQDTLTEQAETQESHL
NT seq 3558 nt NT seq  +upstreamnt  +downstreamnt
atgtctcttctcaaccctgtcctgctgccccccacggtgaaggcctatctgagccaaggg
gagcgcttcatcaaatgggatgatgaaacgacgatagcctctccggttatcctccgtgtg
gatcccaagggctactacttgtactggacatatcagagtaaggagatggagctcctggat
atcaccagcatccgggacacccgctttgggaagtttgccaagatgcccaagagccagaag
ctccgggaagtcttcaacatgaacatccgcgacaacttcctgctgaagacgctcacagtg
gtatccggccctgacatggtggacctcaccttccataacttcgtctcctataaggacaac
gtgggcaaggactgggctgaagacgtactggctctggccaagcacccgctgacggccaac
gcctcccgcagcaccttcctggacaagatccttgtgaagctcaagatgcagcttaaccct
gaggggaagattcccgtgaagaattttttccagatgttccctgctgaccgcaagcgggta
gaagctgccctcagtgcctgccacctccccaaaggcaagaacgatgccatcaatcctgag
gacttcccagagtccgtgtacaagagcttcctcatgagcctctgtcctcggccagaaata
gatgagatcttcacttcctaccactccaaggccaaaccctatatgactaaggagcacctg
gccaaattcatcaaccagaaacagcgcgactccaggctcaattccctgctgttcccgcca
gcgcgtcctgaccaggtgcagggcctcatcgacaagtacgagcccagcggcatcaatgtg
cagcggggccagctgtcccccgagggcatggtgtggtttctctgcgggccggagaacagt
gtgctggcccaggacaagctgctgctgcaccacgacatgacccagccgctcaaccattac
ttcatcaactcctcccacaacacctacctgacagccggccagttctcaggcctctcctct
gctgagatgtaccgccaagtgctgctggcaggctgccgctgcgtggagctggactgctgg
aaggggaagccccccgacgaagagcccatcatcacccacggtttcaccatgaccacagac
atctatttcaaggaagcaatcgaagccattgcagaaagtgcctttaagacctccccttat
ccggtcatcctgtcatttgaaaaccacgtggactcaccccgccaacaggctaagatggcc
gagtactgccggacgatgtttggggatatgctgctcacagaacccctggagaagttcccg
ctgaaacctggcatccccctgcccagccctgaggatctccgaggcaagatcctaatcaag
aacaagaagaaccagttttctggctctgcatcccccagcaaggagctggatggggaggct
gagggtagcagcccacccaatgcccctgtgggtgaagatacagtgtgggctggtgaggaa
ggggctgagttggaggaggaggaggtagaagaggaagaggaggagtcgggaaacctggat
gaagaagagataaagaagatgcagtcagatgagggcacagcgggcctggaggtgacggcc
tacaaggagatgtccagcctggtcaattacatccagcccaccaagttcatctccttcgag
ttctctgcccaaaagaatcgaagttatgttatctcctccttcacggagctcaaggcttac
gacctgctctccaagtcctcagtgcagtttgtggactacaacaagcgccagatgagccgc
atctaccccaagggtacccgcatggactcctccaactacatgcctcagatgttctggaat
gctggttgtcagatggttgccctcaacttccagacgatggacctgcccatgcagcagaac
atggcgcttttcgagttcaacgggcagagtggccacctcctcaagcatgagttcatgcgt
cggtcggacaagcagttcaatcccttctcagtggaccgcatcgacgtggtggtagccacc
accctttccattacggngatttctgggcagttcctgtcagaacgcagcgtgcgcacctat
gtggaagtggagctgtttggccttccgggagatcccaagaggcgctatcgcaccaagcta
tcacccagtaccaactccatcaatcccgtctggaaggaggagccctttgtctttgagaag
atcttgatgcctgagctggcttccctgagagtcgctgtgatggaggaaggcaacaagttt
cttggacaccgcatcattcccatcagtgccctgaattctggataccaccatctctgtctg
cacaacgagagcaacatgccactcaccatgcctgcgctcttcgtcttcctggagatgaag
gactatgtgcctgacacctgggcagatctcactgtggccctcgccaatcctatcaagttc
ttcagtgcccatgataagaaggctgtgaagctcaaggaagccatgggaggccagtccgag
agtcccttccctcttgggaatcaccctgccagccagatcaacggggcatcggctccaaca
agcaacgggtcagcagcagccggggccaagagggaggaggccacgaaagaaactgcggaa
ccgcagaccgccagcctggaggagctgcgggagctgaagggcgtcgtgaagctgcagcgg
cgccaggagaaggagcttcgggaactggggcggcgcggcgtgcggcgctgggaggagctg
ctgcagaggggcgcggcgcagctggccgggctcgggccgccaggcgccgggggcagcggc
gggtgccggggccgcaagctcggcccgggcaagggatctcgaaaaaagaggaccctgccg
ggcgaggacaccgccggggcggcgtcggccgaaggccccgagggcgaggacgtgcgcctg
cgagagctgagggacaggctggagctggagctgctgcagctgggcgaggagcaatgcgag
tgtgtcatgaagctcaaggagcagcacgcggcccagcaaatgaccaagatgatggagctg
gctagggagaaacaggctgcagaacggaagaccctcaaggagaccttggagattgacacc
aaagagatgaagaagaagctggaggccaagaggctggagcggatccaggccatgatgaag
gtcaccacagacaagatggctcaggagaggttgaagagagagattaacaactcccacatc
caggaggtggtgcaggtgatcaagcagatgacggagaacctggagaggcaccaggagaag
ttggaggaaaagcaggcagcctgcctggaacagatccaggagatggaaaaacagttccag
caggaggcgatggcagagtacgaggccaagatgaagggcctggagatggaagtgaaggag
tcagtgaggacctgcctccgggcctgcttcccctctgaggaggaggacaagcctgagaga
ccctgcgtggtctccagggagctgtgtgagcaggacacactcacagagcaggcagagacc
caggagagccacctctga

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