KEGG T01008: 515338

Bos taurus (cow): 515338

Entry

515338 CDS T01008

Gene name

ACACB

Definition

acetyl-CoA carboxylase beta

Orthology

K11262

acetyl-CoA carboxylase / biotin carboxylase [EC:6.4.1.2 6.3.4.14]

Organism

bta Bos taurus (cow)

Pathway

bta00061	Fatty acid biosynthesis
bta00620	Pyruvate metabolism
bta00640	Propanoate metabolism
bta01100	Metabolic pathways
bta04910	Insulin signaling pathway

Class

Metabolism; Carbohydrate metabolism; Pyruvate metabolism [PATH:bta00620]
Metabolism; Carbohydrate metabolism; Propanoate metabolism [PATH:bta00640]
Metabolism; Lipid metabolism; Fatty acid biosynthesis [PATH:bta00061]
Organismal Systems; Endocrine system; Insulin signaling pathway [PATH:bta04910]

SSDB

Motif

Pfam:

ACC_central Carboxyl_trans CPSase_L_D2 CPSase_L_chain Biotin_carb_C Biotin_lipoyl ATP-grasp_4 ATPgrasp_Ter ATP-grasp Dala_Dala_lig_C UPF0150

Other DBs

NCBI-GI:

329112497

NCBI-GeneID:

515338

BGD-bta:

BT28796

UniProt:

Q50HZ7 Q50HZ8 Q50I01 Q50I02 Q50I03 Q50I04

Structure

PDB:

2X24

Position

AA seq 2431 aa
MSDSKQVTKSKRKVSFTPSQEPIPASEGSQEPPQEDCNSSPLPKTPSQAELASHKGPQDT
CQQRPSQSPLPQNPQGNPLSSDDASPARQANGSETEGPEIPNTNDLSAPARPQGQRARTL
SREDRKQAHIKRQLMTNFILGSFDDNSSDEDAGAALFRQSSRKGSRASLGTLSLETAHAA
GETETCAPVIRPSMSGLHLARRGREQKKVDLHRDFTVASPAEFVTRFAGHLVIEKVLIAN
NGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADQYVPVPGGPNNN
NYANVELIVDIAKRIPVQAVWAGWGHASENPKLPELLRKHEIAFLGPPSEAMWALGDKIA
STIVAQTLQIPTLPWNGSGLTVEWAEHSLQEGQRISIPESVYNNGCVKDVDEGLEAAEKI
GFPLMIKASEGGGGKGIRKAETAEDFPILFRQVQSETPGSPVFLMKLAQRARHLEVQILA
DQYGNAVSLFGRDCSIQRRHQKIIEEAPATIATPAVFEFMEQCAVRLAKTVGYVSAGTVE
YLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLHRLKDIRLLYGESP
WGVTPISFETPSNPPIPRGHVIAARITSENPDEGFKPSSGTVQELNFRSSKNVWGYFSVA
ATGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLTNLLETENFQ
NNDIDTSWLDNLIAEKVQAEKPDIMLGVVCGALNVADSMFRTCMTDFLHSLERGQVLPAD
SLLNIVDVELIYGGVKYILKVARQSPTMFVLIMNGSHIEIDAHRLNDGGLLLSCSGNSYT
TYLKEEVDSYRITIGNKTCVFEKENDPTVLRSPSAGKLVKYTVADGEHVEAGGSYAEIEV
MKMTTTLNVQESGRVKYVRRPGAVLEAGCVVARLELDDPSKVRPAEPFTGELPSQPTLPI
LGEKLHQVFHSVLENLTNIMNGYCLPEPIFSIKLKDWVQKLLRALRHPSLPLLELQEIMT
SVSGRVPAPVEKAVRRVMAQYASNITSVLCQFPSQQIATILDCHAATLQRKADREVFFMN
TQSIVQLVQKYRSGARGYMKAVVLDLLRRYLLVEHHFQQAHYDKCVINLREQLKPDMAQV
LDCIFSHSQVAKKNQLVIMLIDELCGPDPSLSDELTSILDELTQLSKSEHCKVALRARQV
LIASHLPSYELRHNQVESIFLSAIDMYGHQFCPENLKKLILSETTIFDVLPTFFYHANKV
VCMASLEVYVRRGYIAYELTSLQHRQFPDGTCVVEFQFMLPSSHPHRMTVPISVTNPELL
RHSTELFMDSGFSPKSQRMGAMVAFQRFEDFVRNFDEVISCFANMPKDTPLFSEARNSLY
SEDDSKSLREEPIHILNVALQHADHQEDEQLVPIFRTFVQSKKNILVECGLRRITFLIAQ
EKEFPKFFTFRARDEFAEDRIYRHLEPALAFQLELSRLRNFDVTAMPCANHKMHLYLGAA
RVKEGAEVTDHRFFIRVIIRHSDLITKEASFEYLQNEGERLLLEAMDELEVAFNNTSVRT
DCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAEVKINIRQTTADSAIPI
RLFITNESGYYLDISLYKEVTDPRSGNILFHSFGNKQGPQHGMLINTPYVTKDLLQAKRF
QAQSLGTTYVYDFPEMFRQALFKMWPSPDKYPKDILTYTELVLDPQGQLVEMNRLPGGNE
VGMVAFKMTLKTLEYPEGRDIILISNDITFRIGSFGPGEDLLYLRASELARAEGIPRVYL
AANSGARIGLAEEIKHMFQVAWVDPEDPHKGIKYLYLTPQDYTRISSLNSVHCKHVEEDG
ESRYVITDIIGKEEGLGVENLRGSGMIAGETSQDYDEIVTISMVSCRALGIGAYLVRLGQ
RVIQVENSHIILTGATALNKVLGRDVYTSNNQLGGVQIMHHNGVSHVTVPDDFEGVCTIL
EWLSYMPKDNRSPVPVVTPKDPIDREIEFQPSRGPYDPRWLLAGRPHPTLKGSWQSGFFD
QGSFKEIMVPWAQTVVTGRARLGGIPVGVIAAETRTVELVVPADPANLDSEAKIIQQAGQ
VWFPDSAYKTAQAIKDFNREKLPLMIFANWRGFSGGMKDMYDQVLKFGAYIVDGLRKYRQ
PVLIYIPPYAEVRGGSWAVMDTSINPLCIEMYADRESRASVLEPEGTVEIKYQKKDLVKT
IRRLDPISKKLVEQLGVSELSDTDRKELEGQLKAREDLLLPMYHQVALHFADLHDTAGRM
LEKGVIYDILEWKTARSFLYWRLRRLLLESQVKQEVLRACPELSHMHVQSMLRRWFVETE
GAVKAYLWDNNQTVVQWLEAHGQASEGLHSTIRENITCLRRDSALKTIQGLVQENPELAM
DSLVYVSQHISPAERAQVIHLLSTTDGPAST

NT seq 7296 nt +upstreamnt +downstreamnt
atgtcagactccaagcaagtcaccaagagtaaacggaaagtgagcttcaccccgagtcag
gagccgattccagcctcagagggatcccaggagccaccgcaggaagactgcaacagcagc
cctctgccaaagacccctagccaggctgagctggcctcccacaaaggaccccaagacacc
tgccagcagaggccctcccaatcacctctgccacagaatccccaaggaaaccccctctcg
tctgatgacgcctccccagcacgccaagccaacgggtcagagactgaaggcccggagatc
ccaaataccaatgacctgtccgcgccagccaggccccagggccagcgagccagaaccctc
tccagagaagacaggaagcaggcacacatcaagagacagctgatgaccaacttcatcctg
ggctcttttgatgacaactcctccgatgaagatgctggtgctgccctgttccgacagtct
tcccggaagggcagccgggccagcctggggaccctgtccctggagactgctcatgccgca
ggcgagactgagacctgtgcccccgttataaggcccagcatgtcggggctccacctggca
agaaggggccgagaacagaagaaagtggacctgcacagagacttcaccgtggcttcccct
gctgagttcgtcacacgctttgcggggcatctggtcatcgagaaggtgctcatcgcgaac
aacggtattgccgccgtgaaatgcatgcgctccatccgcaggtgggcctatgagatgttc
cgaaatgagcgggccatccggttcgtagtcatggtaacgccagaggacctcaaggccaac
gcagagtatatcaagatggcagatcagtatgtccctgtcccaggagggcccaacaacaac
aattacgccaacgtggagctgattgtagacatcgccaagaggatccccgtgcaggcggtg
tgggctggttggggccatgcttctgaaaaccccaaacttccggagctcctgcgcaagcac
gagattgctttcctaggccctcccagcgaggccatgtgggcactaggagacaagattgcc
tccaccatcgtggcccagactctgcagatcccaacgctgccctggaacggaagtggtctg
acggtggagtgggcggaacacagtctacaggaggggcaaaggatcagcatcccagagtcc
gtctacaacaatggttgcgtgaaagatgtagatgaaggcttggaggcagcagaaaaaatt
ggttttcccttgatgatcaaagcttctgaaggcggtggagggaaaggaatccggaaggcg
gagactgctgaggacttccccatcctgttcagacaagtgcagagcgagacccctggctcc
ccagtcttcctcatgaagctggcccagcgtgcccggcacctggaggtccagatcctcgcc
gaccagtacgggaacgcagtgtccctgttcgggcgtgactgttccatccagcggaggcac
cagaagatcatagaggaggcgccggccaccattgccacgccagccgtgttcgagttcatg
gagcagtgtgccgtgcgcctggccaagacggtgggctacgtgagcgcggggactgtcgag
tacctttacagccaggatggcagcttccacttcttggagctgaatccccgcctgcaggtg
gaacatccctgcacggaaatgatcgcggatgtcaacctgcctgctgcccagctgcagatt
gccatgggtgtgccgctgcaccggctgaaggatatccggcttctgtacggagagtccccg
tggggggtgacgcccatttcttttgagacccctagcaaccctcccattccccgaggccac
gtcattgcagccagaatcaccagcgaaaacccagatgaggggtttaagccgagctccgga
acggtccaagaattgaatttccgcagcagcaagaatgtatggggttatttcagcgtggct
gcgactggtggcttacacgaatttgcggattcccagtttgggcactgcttttcctggggg
gagaaccgggaagaggccatttcgaacatggtggtggctttgaaggaactatccatcagg
ggcgacttcaggaccaccgtggaatatctcaccaaccttctggagactgagaactttcag
aacaacgacattgacaccagctggttggataacctcattgctgagaaagtgcaggctgag
aagccagatatcatgctcggggttgtgtgcggagccttgaacgtggccgactccatgttt
agaacatgcatgacggacttcctacactcgctggaaaggggccaggtcctccccgcagac
tctctgctgaacatcgtggacgtggaattaatctatggaggtgtcaagtacattctcaag
gtggcccggcagtctccgaccatgttcgtgctcatcatgaacggctctcacatcgagatc
gacgcccaccggctgaacgacggggggctactgctgtcctgcagcggcaacagctacacc
acctacctgaaggaggaggtggacagttaccgaatcaccattggcaacaagacgtgcgtg
tttgagaaggagaatgaccccacagtcctgagatccccttcggctgggaagctggtgaag
tacactgtggcagacggggaacacgttgaggctgggggcagctacgccgagatagaggtc
atgaagatgaccacgaccctgaacgtgcaggaaagtggccgggtgaagtatgtcaggcgc
ccgggggctgtgttggaagctggctgcgtggtggccaggctggagctcgatgacccttct
aaagtgcgcccggctgagccgttcacgggggagctcccctcacagcccacgctgcccatc
ctcggagagaagctgcaccaggtttttcacagcgtcctggaaaatctcaccaacatcatg
aatggctactgtctgccggagcctatttttagcatcaagctgaaggactgggtgcagaag
ctcctgagggccctccggcacccgtcgctgccgctgctggagcttcaggagatcatgacc
agtgtgtcgggccgcgttcccgcccccgtggagaaggccgtccgcagggtgatggcccag
tacgccagcaacatcacctcggtgctctgccagttccccagccagcagatagccaccatc
ctggactgccacgcagccaccctgcagcggaaggccgaccgggaggtcttcttcatgaac
acccagagcattgtacagctggtccagaagtaccgcagtggggcccgcggctacatgaag
gcggtggtcttggacctcctgcggagatatttactggttgagcaccatttccagcaagcc
cactacgacaagtgtgtgataaacctccgggagcagctgaagccagacatggcccaggtg
ttggactgcatcttctcccactcgcaggtggccaagaagaaccagctggtgatcatgttg
attgatgagctctgtggcccagacccatccctgtccgatgagctgacctccatcctcgac
gagctgactcagctgagcaaaagcgagcactgcaaggtggccctcagagccaggcaggtc
ctgattgcctcccatctcccctcctacgagctgaggcacaaccaagtggagtccattttc
ctgtctgccattgacatgtacggccaccagttctgcccagaaaacctcaagaaattaata
ctctcagaaacaaccatctttgatgtgctgcccactttcttctaccacgctaacaaagtg
gtttgcatggcatccttggaggtctatgtgcggaggggctacatcgcctatgagctaacc
agcctgcagcaccgccagttcccggatggcacctgcgtggtggaattccagttcatgctg
ccctcctcccacccgcaccggatgaccgtgcccatcagtgtcaccaacccggaactgctg
agacacagcacggagctcttcatggacagtggcttctcccccaagtcccagcgaatgggg
gccatggtcgccttccagagattcgaggatttcgtcaggaactttgatgaggtcatctcc
tgctttgccaacatgcccaaggacacccccctcttcagcgaggcccggaattccctgtac
tctgaggacgacagcaagagcctccgagaggagccaatccacatcctaaatgtggccctc
cagcacgcggaccaccaggaggatgagcagctggtgcccattttccgaacattcgtgcag
tccaagaaaaacatccttgtggagtgtggactccgaagaatcacattcctgattgcccaa
gagaaagaatttcccaagtttttcacattcagagcaagagatgagtttgcagaagatcgc
atctaccgtcacttggagccggccctggccttccagctggagctcagccggttgcgaaac
ttcgacgtgaccgccatgccctgcgccaaccacaagatgcacctgtacctgggtgccgcc
agagtgaaggagggcgccgaggtcacggaccacaggttcttcatccgggtcatcatcagg
cactcagacctgatcaccaaggaagcctccttcgagtacctccagaacgagggcgagcgg
ctgctcctggaggccatggacgagctggaggtggcattcaacaacaccagcgtgcgcaca
gactgcaaccacatcttcctcaacttcgtgcccaccgtcatcatggacccctccaagatt
gaggagtcggtgcggtccatggtgatgcgctacggcagccgcctctggaagctccgcgtg
ctccaggctgaggtcaagatcaacatccgccagaccaccgccgacagcgccatccccatc
cgcctcttcatcaccaacgagtcaggctactacctggacatcagcctctacaaggaagtg
accgaccccagatctggaaacatcttgtttcactcctttggcaacaagcaaggcccccag
catgggatgctgatcaacactccctatgtcaccaaggatctgcttcaggccaagcgattc
caggcccagtccctgggtaccacctatgtgtatgacttcccagaaatgttcaggcaggct
ctttttaaaatgtggccctctccggacaagtaccccaaagacatcctgacgtacaccgaa
ctcgtgctggatccgcagggccagctggtggagatgaaccgacttcctggaggaaatgag
gtgggcatggtggccttcaaaatgacgttgaagaccctcgagtaccccgaagggcgtgac
attatcctcatcagcaatgacatcaccttccgtatcggatcctttggccccggagaagac
cttctgtacctgcgggcgtctgagctggcccgggccgagggcatccccagagtctacctc
gcggccaacagtggggcccgtatcggcctggcagaggagatcaagcacatgttccaggtg
gcttgggtggacccggaagacccccacaagggaattaaatacctgtacctgaccccccaa
gactacaccagaatcagctccctgaactccgtccattgtaaacacgtggaggaagatgga
gaatccaggtatgtcatcacggacatcattgggaaggaggagggcctgggcgtagagaac
ctgaggggctcaggcatgattgctggggagacctcccaggactacgacgagatcgtcacc
atcagcatggtgagctgccgggccctcgggatcggggcctacctggtgaggctgggccag
cgagtgatccaggtggagaattcccacatcatcctcacgggggcgacggcgctcaataag
gtcctgggcagagacgtttacacgtccaacaaccagctgggcggtgtgcagatcatgcat
cacaatggcgtctcgcatgtcaccgtgccagatgactttgagggtgtttgtaccatcctg
gaatggctgtcctatatgccaaaggataatcgcagcccagtcccagtcgtcacacccaag
gaccccattgacagagaaattgaattccaaccatctcgcgggccctacgacccccggtgg
ctgcttgcaggaagacctcacccaactctgaagggatcctggcagagtggattctttgac
cagggcagtttcaaggagatcatggtgccctgggcccagactgtggtgacgggacgagca
aggctggggggtatccccgtcggagtgatagctgcagagacgcggacggtggagttggtt
gtgcccgccgaccctgccaacctggattccgaggccaagataatccagcaggctggccag
gtgtggttcccagattcggcctataagacggcccaggccatcaaggatttcaaccgggag
aagttgcccctgatgatctttgccaactggagggggttctccgggggcatgaaagacatg
tatgaccaggtgctaaagttcggagcctacatcgtggatggcctccggaagtacagacag
cccgtcctgatctacatcccgccctatgcggaggtccggggcggctcctgggcagtcatg
gacacctccatcaacccgctgtgcatagagatgtacgcggacagagagagcagagcaagt
gttctggagccagagggaacagtggagattaagtaccagaagaaagatctggtgaagacc
atcagaagactcgaccccatttccaagaagctcgtggaacagctcggagtgtctgagctc
tcagacacggaccgcaaggagctggagggccagctgaaggcccgggaggacctgctgctg
cccatgtaccaccaggtggcgctgcactttgccgacctccacgacacggcgggcaggatg
ctggagaagggcgtcatttacgacatcctggagtggaagacggcccgcagcttcctgtac
tggcgcctgcgccgcctgctgctggagagccaggtgaagcaggaggtcctgagggcctgc
cccgagctcagccacatgcatgtgcagtccatgctgcgccgctggtttgtggagacggag
ggcgctgtcaaggcctacctgtgggacaacaaccagacggtggtgcagtggctggaggcg
cacgggcaggcgagcgaggggctgcactccaccatccgggagaacatcacgtgcctgagg
cgggactccgccctcaagaccatccagggcctggttcaagaaaaccccgagctggccatg
gactcactggtgtacgtcagccagcacatcagcccggccgagcgggcccaggtcattcac
ctcctgtccaccacggacggcccggcctctacctga

All links

Pathway (5)   
   KEGG PATHWAY (5)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (5)   
   KEGG ENZYME (2)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (11)   
   UniGene (2)   
   BGD-BTA (1)   
   OC (1)   
Protein sequence (7)   
   UniProt (6)   
   RefSeq(pep) (1)   
DNA sequence (21)   
   RefSeq(nuc) (1)   
   GenBank (10)   
   EMBL (10)   
3D Structure (1)   
   PDB (1)   
Protein domain (11)   
   Pfam (11)   
All databases (76)   

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