KEGG   Bos taurus (cow): 515669Help
Entry
515669            CDS       T01008                                 

Gene name
PLCB3
Definition
phospholipase C, beta 3 (phosphatidylinositol-specific) (EC:3.1.4.11)
Orthology
K05858  
phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
bta  Bos taurus (cow)
Pathway
Inositol phosphate metabolism
Metabolic pathways
Rap1 signaling pathway
Calcium signaling pathway
Chemokine signaling pathway
Phosphatidylinositol signaling system
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Wnt signaling pathway
Gap junction
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
Dopaminergic synapse
Long-term depression
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Endocrine and other factor-regulated calcium reabsorption
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Alzheimer's disease
Huntington's disease
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Amoebiasis
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Class
Metabolism; Carbohydrate metabolism; Inositol phosphate metabolism [PATH:bta00562]
Environmental Information Processing; Signal transduction; Rap1 signaling pathway [PATH:bta04015]
Environmental Information Processing; Signal transduction; Wnt signaling pathway [PATH:bta04310]
Environmental Information Processing; Signal transduction; Calcium signaling pathway [PATH:bta04020]
Environmental Information Processing; Signal transduction; Phosphatidylinositol signaling system [PATH:bta04070]
Cellular Processes; Cell communication; Gap junction [PATH:bta04540]
Organismal Systems; Immune system; Chemokine signaling pathway [PATH:bta04062]
Organismal Systems; Endocrine system; Insulin secretion [PATH:bta04911]
Organismal Systems; Endocrine system; GnRH signaling pathway [PATH:bta04912]
Organismal Systems; Endocrine system; Estrogen signaling pathway [PATH:bta04915]
Organismal Systems; Endocrine system; Oxytocin signaling pathway [PATH:bta04921]
Organismal Systems; Endocrine system; Thyroid hormone synthesis [PATH:bta04918]
Organismal Systems; Endocrine system; Thyroid hormone signaling pathway [PATH:bta04919]
Organismal Systems; Endocrine system; Melanogenesis [PATH:bta04916]
Organismal Systems; Circulatory system; Adrenergic signaling in cardiomyocytes [PATH:bta04261]
Organismal Systems; Circulatory system; Vascular smooth muscle contraction [PATH:bta04270]
Organismal Systems; Digestive system; Salivary secretion [PATH:bta04970]
Organismal Systems; Digestive system; Gastric acid secretion [PATH:bta04971]
Organismal Systems; Digestive system; Pancreatic secretion [PATH:bta04972]
Organismal Systems; Excretory system; Endocrine and other factor-regulated calcium reabsorption [PATH:bta04961]
Organismal Systems; Nervous system; Glutamatergic synapse [PATH:bta04724]
Organismal Systems; Nervous system; Cholinergic synapse [PATH:bta04725]
Organismal Systems; Nervous system; Dopaminergic synapse [PATH:bta04728]
Organismal Systems; Nervous system; Serotonergic synapse [PATH:bta04726]
Organismal Systems; Nervous system; Long-term potentiation [PATH:bta04720]
Organismal Systems; Nervous system; Long-term depression [PATH:bta04730]
Organismal Systems; Nervous system; Retrograde endocannabinoid signaling [PATH:bta04723]
Organismal Systems; Sensory system; Inflammatory mediator regulation of TRP channels [PATH:bta04750]
Organismal Systems; Environmental adaptation; Circadian entrainment [PATH:bta04713]
Human Diseases; Neurodegenerative diseases; Alzheimer's disease [PATH:bta05010]
Human Diseases; Neurodegenerative diseases; Huntington's disease [PATH:bta05016]
Human Diseases; Infectious diseases; Amoebiasis [PATH:bta05146]
Human Diseases; Infectious diseases; Chagas disease (American trypanosomiasis) [PATH:bta05142]
Human Diseases; Infectious diseases; African trypanosomiasis [PATH:bta05143]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
29
AA seq 1234 aa AA seqDB search
MAGARPGVHALQLEPPTVVETLRRGSKFIKWDEEASSRNLVTLRVDSNGFFLYWTGPNME
VDTLDISSIRDTRTGRYARLPKDPKIREVLGFGGPDARLEEKLMTVVAGPDPVNTTFLNF
MAVQDDTAKVWSEELFKLAMNILAQNASRNTFLRKAYTKLKLQVNQDGRIPVKNILKMFS
ADKKRVETALESCGLNFNRSESIRPDEFSLEIFERFLNKLCLRPDIDKILLEIGAKGKPY
LTLEQLMDFINQKQRDPRLNEVLYPPLRPSQARLLIEKYEPNKQFLERDQMSMEGFSRYL
GGEENGILPLEALDLSTDMTQPLSAYFINSSHNTYLTAGQLAGTSSVEMYRQALLWGCRC
VELDVWKGRPPEEEPFITHGFTMTTEVPLRDVLEAIAETAFKTSPYPVILSFENHVDSAK
QQAKMAEYCRSIFGDALLIDPLDKYPLAPGVPLPSPQDLMGRILVKNKKRHRLGSGVPDS
SVRKRPLEQSNSALSESSATTEPSSPQLGSPSSDSCPGLSNGEEVGLEKPSLEPRKSLGE
EGLQRGPDVLGPAYREDEEEDEEEEEQTDPKKPTTDEGTASSEVNATEEMSTLVNYIEPV
KFKSFEAARKRNKCFEMSSFVETKAMEQLTKSPMEFVEYNKQQLSRIYPKGTRVDSSNYM
PQLFWNVGCQLVALNFQTLDVPMQLNAGVFEYNGRSGYLLKPEFMRRPDKSFDPFTEVIV
DGIVANAVRVKVISGQFLSDRKVGIYVEVDMFGLPVDTRRKYRTRTSQGNSFNPVWDEEP
FDFPKVVLPTLASLRIAAFEEGGKFVGHRILPVSAIRSGYHYICLRNEANQPLCLPALLI
YTEASDYIPDDHQDYAEALINPIKHVSLMDQRAKQLAALIGESEAQSGPETSQETQTQQL
GCQLNPHPTPSPLDASPRRPPGPATSPTSSSISSSISSPGQRDDLIASILSEVAPAPLDE
LRGHKALVKLRSRQERDFRELYKKHQRKAVALTRRLLDNLAQARAGSRCRQRPGVLSGED
ERAEEEEVSRYQEFQKKQVQCLLELREAQVDTEADRRLEHLQQAQLKLREVVLDAHMTQL
KKLKEINEREKKELQKILDRKRHNSISEAKTREKHKKEAELTEINRRHITESVNSIRRLE
EAQKQRQERLVAGQQQILQQLAEEEPKLLAQLVQDCQEQRERLPQEIRWSLLGETQEGLG
DGHLVACASNGHAPGSSGHLPGADSESQEETTKL
NT seq 3705 nt NT seq  +upstreamnt  +downstreamnt
atggcgggcgccaggcccggcgtccacgcgctgcagctagagccgcccaccgtcgtggag
accctgcggcgcgggagtaagttcatcaaatgggacgaggaggcctccagtcggaacctg
gtaaccctgcgagtggactccaatggcttcttcctgtactggacgggacccaacatggag
gtggacacactcgacatcagttccatcagggacaccaggacgggccgttatgcccgcctg
cccaaggaccccaagatccgggaggtgttgggctttgggggccctgatgcccggttggag
gagaagctgatgacagtggtggccgggccagacccggtgaatacaacattcttgaacttc
atggccgtgcaggatgatacagccaaggtctggtccgaggagctcttcaagttggctatg
aacatcctggctcagaacgcctcccggaacaccttcttgcgcaaagcatacacgaagctg
aagctgcaggtaaaccaggatggacggattccagtcaagaacatcctgaagatgttctca
gcagacaagaagcgggtagaaactgcactggaatcctgtggcctcaatttcaaccgaagc
gagtccatccggcctgacgagttttccttggaaatctttgagcggttcctgaacaagctg
tgtctgcggccagacattgataagatcctgctggagataggtgccaagggcaaaccttac
ctgacgctggagcagctcatggatttcattaaccagaagcagcgggacccgcggctcaac
gaagtgctgtacccacctctgcggccctcccaggcccgactgctcatcgagaagtacgaa
cccaacaagcagttcctggagcgagaccagatgtccatggagggcttcagccgctacctg
ggaggtgaggagaatggcattctgccgcttgaggccttggatctgagcacagacatgacc
cagccgctcagcgcctacttcatcaattcctcgcacaacacctatctcacggcggggcag
ctggccggaacctcgtcggtggagatgtaccggcaggcgctgttgtggggctgccgctgt
gtggagctggacgtgtggaaggggcggccgcccgaggaggagccgttcatcacgcacggc
ttcaccatgaccacggaggtgccgctgagagacgtgcttgaggccatcgcggagacggcc
ttcaagacttcgccctaccccgtcatcctctcctttgagaaccacgtggactcggcgaaa
cagcaggccaagatggctgagtactgccgctccatctttggggatgctctgctcatcgac
cccctggacaagtacccgctggccccaggcgtccccctgcccagcccccaggacctgatg
ggccgcatcctggtgaagaacaagaagcggcaccgactcggcagcggcgtccccgacagc
tccgtgcgcaagcggccactggagcagagcaactcggccctgagcgagagctccgccacc
accgagccctcctcgccccagctcgggtcccccagctctgacagctgcccaggcctgagc
aatggggaggaggtgggcctcgagaagcccagcctggagcctcggaagtctctgggggag
gagggtttgcagcggggccctgatgttcttggacctgcctaccgggaggatgaggaagag
gacgaggaagaggaggaacaaacggaccccaaaaagccgaccacggatgagggcactgcc
agcagtgaggtcaacgccactgaggaaatgtccacactcgtcaactatatcgagcctgtc
aagttcaagtccttcgaggctgctcgaaagaggaacaagtgcttcgagatgtcgtccttc
gtggagaccaaggccatggagcaactgaccaagagccccatggagtttgtggaatacaac
aagcagcagctcagccgcatctaccccaagggcacccgcgtggactcgtccaactacatg
ccccagctcttctggaacgtgggctgccagctcgttgcactcaactttcagaccctggat
gtgccaatgcagctcaacgccggcgtgtttgagtacaacgggcgcagcggctacctactc
aagcctgagttcatgcggcggccggacaagtcctttgaccccttcaccgaagtcatagtg
gacggcatcgtggccaatgccgtgcgggtcaaggtgatctcggggcagttcctgtccgac
aggaaggtgggaatctacgtggaggtagacatgttcgggcttcctgttgacacgcggcgc
aagtaccgcacacggacctcacaggggaactcgttcaaccctgtgtgggatgaggagcca
ttcgacttccccaaggtggtgctgcccacactggcttcgctgcgcatcgcggcctttgag
gaggggggcaagttcgtggggcaccggatcctgcctgtctctgctatccgctcagggtac
cattacatctgcctgcggaatgaggccaaccagccgctgtgcctgccagccctgctcatc
tacaccgaggcctccgactacatccccgacgaccaccaggactatgcagaggccctgatc
aaccccatcaagcatgtcagcctgatggaccagagggccaagcagctggctgccctcatt
ggggagagcgaggctcagtctggcccggagacgagccaggagacccagactcagcagctg
gggtgccagctgaacccacacccgacgcccagcccgctggacgcctccccgcgccggccc
ccaggccccgccacctccccgaccagctcctccatcagctcctccatcagcagcccaggt
cagcgcgatgatcttatcgccagcatcctctcagaggtggccccggccccgctggacgag
ctccgaggccacaaggccctagtgaagctccggagccggcaagagcgagacttccgggag
ctgtacaagaaacatcagcggaaggccgttgccctcacgcgccggttgctcgacaacctg
gcccaggcccgtgcggggagcaggtgccgacagcggcctggtgtcctaagcggggaggac
gagagggcagaagaggaagaggttagcaggtatcaagagttccagaagaaacaggtgcag
tgtctgctggagctgagggaggcccaggtggacacagaggcggatcggaggctggagcac
ctgcagcaggctcagctgaagctcagggaggttgtcctggacgctcacatgactcagttg
aagaaactgaaggagataaacgagagggagaagaaggagctgcagaagatcctggacagg
aaacgccacaacagcatctcagaggccaagaccagggagaaacataagaaagaggcggaa
ctgacagagattaaccgtcggcacatcactgagtcagtcaactccatccgtcggctggag
gaggcccagaagcagcggcaggaacgccttgtggccggacagcagcagatcctccaacag
ctggcggaagaggagcccaagctgctggcccagctggtccaggactgtcaggagcagcgg
gagaggctgccccaggagatccgctggagcctgctgggcgagacacaggagggactgggg
gacgggcatctggtcgcctgtgccagcaacggtcacgcgcctgggagcagcgggcacctg
cccggcgctgactcagagagccaggaggagactacaaagctctga

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