KEGG   Bos taurus (cow): 516175Help
Entry
516175            CDS       T01008                                 

Gene name
PPP1CA
Definition
protein phosphatase 1, catalytic subunit, alpha isozyme (EC:3.1.3.16)
Orthology
K06269  
serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
Organism
bta  Bos taurus (cow)
Pathway
mRNA surveillance pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Oocyte meiosis
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Hippo signaling pathway
Focal adhesion
Platelet activation
Long-term potentiation
Dopaminergic synapse
Inflammatory mediator regulation of TRP channels
Regulation of actin cytoskeleton
Insulin signaling pathway
Oxytocin signaling pathway
Amphetamine addiction
Alcoholism
Herpes simplex infection
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:bta00001]
 Genetic Information Processing
  Translation
   03015 mRNA surveillance pathway
    516175 (PPP1CA)
 Environmental Information Processing
  Signal transduction
   04390 Hippo signaling pathway
    516175 (PPP1CA)
   04024 cAMP signaling pathway
    516175 (PPP1CA)
   04022 cGMP - PKG signaling pathway
    516175 (PPP1CA)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    516175 (PPP1CA)
  Cell growth and death
   04114 Oocyte meiosis
    516175 (PPP1CA)
  Cellular commiunity
   04510 Focal adhesion
    516175 (PPP1CA)
 Organismal Systems
  Immune system
   04611 Platelet activation
    516175 (PPP1CA)
  Endocrine system
   04910 Insulin signaling pathway
    516175 (PPP1CA)
   04921 Oxytocin signaling pathway
    516175 (PPP1CA)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    516175 (PPP1CA)
   04270 Vascular smooth muscle contraction
    516175 (PPP1CA)
  Nervous system
   04728 Dopaminergic synapse
    516175 (PPP1CA)
   04720 Long-term potentiation
    516175 (PPP1CA)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    516175 (PPP1CA)
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    516175 (PPP1CA)
  Substance dependence
   05031 Amphetamine addiction
    516175 (PPP1CA)
   05034 Alcoholism
    516175 (PPP1CA)
  Infectious diseases
   05168 Herpes simplex infection
    516175 (PPP1CA)
Enzymes [BR:bta01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     516175 (PPP1CA)
Protein phosphatases and associated proteins [BR:bta01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    Catalytic subunits
     516175 (PPP1CA)
Transcription machinery [BR:bta03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     516175 (PPP1CA)
Spliceosome [BR:bta03041]
 Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   Other SAPs
    516175 (PPP1CA)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
BGD-bta: 
Ensembl: 
UniProt: 
Position
29
AA seq 330 aa AA seqDB search
MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLK
ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL
LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL
QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHD
LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAD
KNKGKYGQFSGLNPGGRPITPPRNSAKAKK
NT seq 993 nt NT seq  +upstreamnt  +downstreamnt
atgtccgacagcgagaagctcaacctggactctataatcggacgcctgctggaagtgcag
ggctccaggcctggaaagaatgtacagctgacggagaacgagatccgtggtctgtgcctc
aaatcccgggagattttcctgagccagcccattcttctggagctggaggcacccctcaag
atctgcggtgacattcatggccagtactatgatcttctgcggctgttcgagtacggtggc
ttccctccagagagtaactacttgttcctgggggactacgtggacaggggcaagcagtct
ttggagaccatctgcctgctgctggcctataagatcaagtacccagagaacttcttcctg
ctccgtgggaaccacgagtgtgccagcatcaaccgcatctacggcttctatgatgagtgc
aagagacgctacaacatcaaactgtggaagaccttcactgattgcttcaactgcctgccc
atcgctgccatcgtggacgagaagatcttctgttgccatggagggctgtccccagaccta
cagtccatggagcagatccggcgtatcatgcggcccacagatgtgcctgaccagggcctg
ctctgtgacctgctgtggtctgaccctgacaaggacgtgcagggctggggtgagaatgac
cgcggcgtctcctttacatttggagctgaggtggtggccaagttcctgcacaagcatgac
ctggacctcatctgccgggcacaccaggtagtagaagacggctatgagttctttgccaag
cggcagctggtgacactcttttcagcccccaactactgcggcgagtttgacaatgcaggt
gccatgatgagtgtggacgagacgctcatgtgctccttccagatcctcaagcccgctgac
aagaacaaggggaaatacgggcagttcagtggcctgaaccctggaggccggcccatcacc
ccaccccgcaactccgccaaagccaagaaatag

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