KEGG   Bos taurus (cow): 519037Help
Entry
519037            CDS       T01008                                 

Gene name
PLCE1
Definition
phospholipase C, epsilon 1 (EC:3.1.4.11)
Orthology
K05860  
phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
Organism
bta  Bos taurus (cow)
Pathway
Inositol phosphate metabolism
Metabolic pathways
Ras signaling pathway
Rap1 signaling pathway
Calcium signaling pathway
cAMP signaling pathway
Phosphatidylinositol signaling system
Thyroid hormone signaling pathway
Proteoglycans in cancer
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:bta00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    519037 (PLCE1)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    519037 (PLCE1)
   04015 Rap1 signaling pathway
    519037 (PLCE1)
   04020 Calcium signaling pathway
    519037 (PLCE1)
   04070 Phosphatidylinositol signaling system
    519037 (PLCE1)
   04024 cAMP signaling pathway
    519037 (PLCE1)
 Organismal Systems
  Endocrine system
   04919 Thyroid hormone signaling pathway
    519037 (PLCE1)
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    519037 (PLCE1)
Enzymes [BR:bta01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     519037 (PLCE1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
BGD-bta: 
Ensembl: 
Position
26
AA seq 2297 aa AA seqDB search
MTSEEMAGSVLRPVSQRKVISAQSTVDESNDKVSGISVPKSHPVRQSGETSHTISQPTKL
TEESSGSNAPQIFSVAREKITSDENSNEKCWEKSMPDSVKNLNINCNSILKNHQHGPPQS
QFYETCNSITEEGLCLETGIPSSLEGKVFPGIQLEIDTSPMGMSPLGTQSAIIETSRAHP
ESNMAVFHLRYEVDRRMSDSFCPLSDNLILDDCGNCVLPAVGEEQEKNYMAYTCKLMELT
NNCDNKNRQLQCDHCDPLNDKYLCFEGSCPKADVVCSSDSFCREDFTDSPPAKTFLSHFE
DFPDNCEEVEEDLFKNKKERSAWLVRRFCKNDKEVKKSVFTGTRAIVRTLPSGHIGLEAL
SYIDQKKNGLLLPPGRVMERLSTMVVRQDGSQGLSEAQWYPIYSAVRRGEATEQTIRSLL
HFFAKLPASETAHERISVGPYLKQCVRDTVCEYRATLQRTSISQYITGSLLEATTSLGAR
SSLLNSFGGSTGRMMLKERQPGTSMANSSALPSSSAGISKELIDLKPLIQFPEEVASILM
EQEQNIYRRVLPVDYLFFLTRGLGTTERQRSLPCLKASISASILTSQKGEHNALEDLVMR
FNEVSSWVTWLILAAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKMW
QFMDQSDLETMRSLKDAMAQHESSCEYRKVVTRALHIPGCKVVPFCGVFLKELCEVLDGA
SGLMKLCPRYNSQEETLEFVADYSGQDNFLQRVGQNGLKNSEKESTVNSIFQIIRSCSRS
LETEEEDSSSEGSSSRKNSLKDKARWQFIIGDLLDSENDIFEQPKEWDSHGSEEPQKAFD
HGTELIPWYVLSIQADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWIKPTTAS
PASAKAKLGVLSNTSEPGKFPLLGNAGLSGLVEGILDLFSAKAVYMGHPNIDIHTVCVQN
KLSNMSLSETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTRAVRKMRKFPDQRQ
HWLRKQYVSLYQEDGRYEGPTLAQAVELFGGRRWSTRNPSPGTSAKSAEKPNTLSISNTK
KKKKILMRGESGEVTDDEMATRKARTHKESRSRSGSDPQDVNEQEESEANAIMNPPNPLP
SRRAHSLTTTGPPTLAAGTASPIRPVSSPVLPASNRSPTSAWNSSSGWPGKIKGGMQGFQ
SFMVSDSSMSFVEFVELFKSFSVRSRKDLKDLFDIYAVPCDRAGSEAAPLYTNLTIDENI
SGLQPDLDLLTRNVSDLGLFIKTKQQLSDNQRQISDAIAAASIVTNGTGVESTSLGVFGV
GILQLNDFLVNCQGEHYTYDEILSIIQKFEPSVSMCHQGLMSFEGFARFLMDKDNFASKN
DESQENVKEMQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDGD
DGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEIFKTV
FGEKLVAKFLFESDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLASMQA
QAYNGSNANSPPANNEEEEDEEDEYDYDYESLSDDNILEDRPENKSCNDKLQFEYNEEIP
KRIKKADNSACNKGKVYDMELGEEFYLPQNKKESRQIAPELSDLVIYCQAVKFPGLSTLN
ASGSSRGKERKSRKSIFGNNPGRMSPGETAPFNKTSGKSSCEGMRQAWEDSAFSVNPTTS
LSAIIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTACQLLRTYPAATRIDSSNPNPLLF
WLHGIQLVALNYQTDDLSLHLNAAMFEANGGCGYVLKPPVLWDKNCSMYQKFSPLERDLD
SMEPAIYSLTIVSGQNVCPSNSTGSPCIEVDVLGMALDSCHFRTKPIHRNTLNPMWNEQF
LFRVHFEDLVFLRFAVVENNSSVVTAQRIISLKALKRGYRHLQLRNLHNEVLEISSLFIN
SRRMEENSSGNTVLASLMFNTEERKCLQTHRVTVHGVPGPEPFTVFSINGGTKAKQLLQQ
ILVMDQDTKPIATDYFLMEEKYFISKEKNECRKQPFQRAIGPEEEIVQILSSWFPEEGYV
GRIVLKTQQENLEEKSIAQDDKEMLLSSEEDSFFVQVHDVSPEQPRTVIKAPRVSTAQDV
IQQTLCKAKYSYSILSNPNPSDYVLLEEVVKDTANRKSSTPKASQRVLLDQECVFQAQSK
WKGAGKFILKLKEQVQASREDKKKGISFASELKKLTKTKQPRGPTSPSQVLASENVQNKE
EKPVGGLPSSDTIDYRQ
NT seq 6894 nt NT seq  +upstreamnt  +downstreamnt
atgacttctgaagaaatggcaggttctgttctcagacctgtgagtcagagaaaagtgatc
tctgctcagtcaactgtagatgaaagtaatgataaggtctcgggcatcagtgttccgaag
tctcatcctgtcaggcagagtggggagacttctcataccatctcgcaaccgaccaaactt
acagaagaatcttctggaagcaacgcgccccagattttctcagtagcaagggagaaaata
accagtgacgagaacagtaatgaaaagtgctgggagaaaagcatgccagattctgtgaaa
aaccttaacattaactgcaacagcatattgaaaaaccatcagcacggccctcctcagagc
cagttttatgaaacgtgcaattctatcacagaggaaggtctgtgtttggaaactggaatc
ccttcttcactggaaggaaaggtgttccctggaattcaactggaaatagacacatctccc
atgggcatgagtccattaggaactcagtcggccatcatagagacaagcagggcacaccct
gaaagcaacatggcagtgtttcacttgcgttacgaagttgacagaagaatgtcagacagt
ttctgtcccctgtcagataacttgattttggatgattgtggaaactgtgtactacctgcc
gttggtgaggaacaagagaaaaattacatggcatatacttgcaaactgatggaattgaca
aataactgtgacaataagaataggcagctgcagtgtgatcattgtgaccccttgaatgac
aaatacttgtgctttgaaggctcttgcccaaaggccgatgtggtatgttcaagtgacagc
ttttgcagggaggattttactgacagtccacctgccaagacctttctgagccattttgag
gacttccccgataattgtgaagaggtagaagaagatttgttcaaaaataaaaaggagcgg
tctgcttggttagtgaggagattttgcaaaaatgacaaggaagttaagaaatctgtgttt
actgggacaagggcaattgtgagaactttgccttctggtcacattggactggaggctttg
agttacattgatcagaagaaaaatggtctcttattgcctcctgggagagtcatggaacgg
ctgtcaacaatggtggttaggcaagatggttcccaaggtctgtcagaagcccagtggtat
ccgatctacagtgcagtgagaaggggagaagccacagaacagacaattagatctcttctc
catttcttcgccaagctcccagcctccgagacagcccatgagaggatcagtgtcggtccg
tacttaaagcaatgtgtccgagacacagtgtgtgagtatcgtgccaccttgcaaaggact
tccatatctcagtatatcaccggctctctcctggaagccaccacatctttaggagcaaga
agcagcctcctcaattcttttggaggatccacgggacgaatgatgctgaaagaacgccaa
ccaggcacctctatggccaactccagtgcccttccttcaagttcagctgggatcagcaag
gaactgattgatctgaagcccctcatccagttcccagaggaagtcgccagcatcctgatg
gagcaggagcaaaatatttaccgaagggtcttgccagttgactatcttttcttcttgacc
cggggcttgggcacaacagaacgccagaggtccctgccctgcctcaaagcatccatctca
gcatccattcttacctcccagaagggagagcacaatgccctcgaagatcttgtgatgaga
tttaatgaggtgagctcctgggtgacgtggctgatcctcgcggcgggctccatggaagag
aagcgggaagtcttctcatacttggttcatgtggccaaatgctgctggaacatgggcaac
tacaatgccgtcatggagttcttggccggcctcaggtcaagaaaagttttaaaaatgtgg
cagtttatggaccagtctgatctggagaccatgaggagcctgaaggacgccatggcccag
cacgagtcttcctgcgagtacaggaaggtggtgacccgagcgctgcacatccccggctgc
aaggtggttcccttctgcggggtgtttctgaaagagctctgtgaggtgctggacggagcc
tctggcctcatgaagctttgcccgaggtacaattcgcaggaagaaactctggagtttgta
gccgattatagtggacaagataatttcttacaacgagtgggacagaatggcttaaagaat
tcagagaaggagtccactgtcaacagcatctttcagatcatcaggagctgcagtcgaagt
ctggagacagaggaggaggacagctccagtgaagggagcagctcaaggaaaaattccctg
aaggataaagcccgatggcagtttataatcggagatttgttggattctgaaaatgacatc
tttgagcagcccaaagagtgggactctcatggatcggaggagccacagaaagcctttgac
catgggacagagctcatcccatggtatgtgctgtccatccaagccgatgtgcaccagttc
ctgttgcagggggccacggtcatccactatgatcaggacacgcacctctctgcccgctgc
ttcctccagcttcagcctgacaatagcaccttgacctggataaaacccaccactgcttcc
ccagccagtgctaaagcaaaacttggtgtgctcagtaacacgtctgagcctggcaaattc
ccgttactgggcaatgctggattaagtggcctggtggaggggatcttggatctgttttca
gcaaaggctgtgtacatgggacaccctaacattgatatacacactgtgtgtgttcagaac
aaactgagtaacatgtctctctcagagactggcgtgacactgctctacgggctgcagacc
acggacaatagattactgcactttgtggcgccaaagcacacagctaaaatgctcttcagt
ggattgttggagctcacgagagctgtgaggaagatgaggaagttccctgaccaaagacag
cattggctgcggaaacagtacgtcagcctctaccaggaggatggacgatatgaaggccca
actttggctcaagctgtagagctgtttggtggcagacgatggagtactcgaaaccccagc
cctgggacatcagcaaagagcgctgagaagcccaacaccttgagtataagcaacaccaag
aaaaagaagaaaatccttatgaggggtgagagtggagaggtgacggatgatgagatggcc
acccgcaaggccagaacacacaaagagagccggagccggagtggctctgatcctcaagat
gtcaacgaacaagaagaatcagaggcaaatgccatcatgaaccctcccaaccctctccct
tccagaagagcccactccttgaccacgactgggccccctaccttggctgccgggacagca
tctcccatcaggccagtgtcctctcctgtgctgcctgcttccaacaggagcccaaccagt
gcttggaacagcagcagcggctggccagggaagatcaaaggagggatgcagggctttcag
agcttcatggtttcagacagcagcatgagtttcgtggaatttgttgagctgttcaagtca
ttcagtgtgaggagccgcaaggacctgaaggacctctttgacatctacgccgtaccctgt
gaccgagctggctctgaggcagcccccctctataccaacctgaccattgacgaaaatatc
agcggtcttcagcctgacctagatttgttgaccagaaatgtctcagatttgggattattc
atcaagactaaacagcagctgtctgacaaccagaggcagatatctgatgccattgctgct
gccagtattgtgacaaatggcaccggggtggagagcacatctctgggtgtgtttggagtt
ggtatcctccagctcaatgacttcctagtgaattgccaaggagaacactatacttatgat
gaaatcctcagcattatccagaagttcgagcctagcgttagtatgtgtcatcaaggccta
atgtcatttgaaggatttgcaaggtttctaatggataaagataattttgcctcgaaaaat
gatgagtcacaggagaacgttaaagaaatgcagctgcccctctcctactattacattgaa
tcttcacacaatacctacctcacgggccatcagctcaaaggagaatcctcagtagaactc
tacagccaggtcctcctgcaaggctgtaggagtgtagagttggactgctgggacggagat
gatggaatgcccatcatttatcatggacacaccctgacaaccaagatccccttcaaggaa
gtggttgaagccatcgatcgcagtgccttcatcaactctgacctacccatcatcatatcg
attgagaaccactgctcattgcctcagcaacgaaaaatggcagaaattttcaagactgtg
tttggagaaaaactggtggctaaattcttatttgagagtgatttctcagatgatcctatg
ctcccctcacctgaccaactcagaaggaaagtgcttctcaaaaataagaaattaaaagcc
catcagacaccggtggatatcttaaagcaaaaggctcatcagctagcatccatgcaagct
caggcttataatggtagcaatgccaactccccacctgctaataatgaggaagaggaagat
gaagaggatgaatatgattatgattatgaatccctctctgatgacaacattctagaagac
agacctgaaaataaatcatgtaatgacaaacttcagtttgagtataatgaagaaatcccc
aagaggataaagaaagcagataactctgcttgcaacaaagggaaggtttatgacatggaa
ctgggagaagaattttatcttcctcagaataaaaaggaaagcagacagattgcaccagag
ctttctgaccttgtcatctattgccaagcagtaaaattcccaggcctgtcaactctaaat
gcatctggctctagcagaggaaaagaaaggaaaagcaggaagtccatttttggcaacaat
ccgggcagaatgagccccggggagacagcaccatttaacaaaacatctggaaaaagttcc
tgtgaaggaatgcgacaggcctgggaggactctgctttctccgtcaacccaaccacgtcc
ctcagcgctatcattagaactcccaaatgctaccatatctcctcactgaatgaaaatgcc
gccaaacgtctgtgtcgcaggtattctcagaaactcatccagcacaccgcctgccagctg
ctgcggacgtacccggctgccacccgcatcgactcctccaaccccaaccccctcctgttc
tggctccatgggatacagctcgtggcgctcaactaccagacagatgatctctctttacat
ttaaatgccgccatgtttgaggccaatggtggctgcggttatgttctgaaacccccagtt
ctgtgggacaagaactgttccatgtatcagaagttctcccccttggaaagagacctggac
agcatggagcctgccatctattctttaactattgtctctgggcagaacgtgtgcccgagt
aacagcacggggagcccatgtatcgaagtcgatgtcctgggcatggccctggacagctgc
cacttccgcacgaagcccatccaccgcaatactctgaaccccatgtggaacgaacagttt
cttttccgggttcacttcgaagatctcgtatttcttcgttttgctgtcgtggagaacaac
agctcggtggtcactgctcagagaatcatctccctcaaggctctaaagcgaggatatcga
catcttcagctgagaaatctccacaatgaagtcttggaaatctctagtttattcataaac
agcaggaggatggaagaaaattcttccggcaatactgtgctggcctctctgatgtttaat
acggaagaaagaaaatgtttgcagactcacagagtcacagtgcatggcgtcccaggccca
gagccctttactgttttctctataaacggaggcactaaggcaaagcagcttctccaacaa
attctcgttatggatcaagataccaaacctattgccacagattattttttaatggaggaa
aaatatttcatatctaaagagaagaatgaatgtaggaaacagccgttccagagagccatt
ggtccagaagaagagatcgtgcagattttaagcagctggtttccagaagagggctatgtt
ggcaggattgtcttaaaaacccagcaggaaaacctggaagagaagagcattgcacaagat
gacaaggagatgctcctgagctcagaggaggacagcttctttgtccaggtgcatgacgtt
tccccagagcaaccacgcacggtcatcaaggcgccgcgtgtcagcaccgcgcaggatgtc
attcagcagaccttatgcaaagccaaatattcctatagcatcctgagcaaccccaacccg
agtgactatgtgcttttggaagaggtggtgaaagacaccgccaacaggaaatcttccacc
ccaaaggcctcccagcgcgtccttttggatcaggagtgtgtgtttcaagctcaaagcaag
tggaaaggtgcaggaaaattcatccttaagctaaaggaacaggtgcaggcatctcgagaa
gataaaaaaaaaggcatctcttttgcaagcgaactcaagaagctcaccaagactaaacag
ccccgaggacccacatcaccttctcaggtcttggcctcagaaaacgtccaaaacaaggaa
gagaaacctgtgggtggcttgccttccagtgacaccatagactaccgacagtga

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