KEGG   Bos taurus (cow): 526469Help
Entry
526469            CDS       T01008                                 

Gene name
MAP2K4
Definition
(RefSeq) mitogen-activated protein kinase kinase 4
  KO
K04430  
mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
Organism
bta  Bos taurus (cow)
Pathway
MAPK signaling pathway
ErbB signaling pathway
Toll-like receptor signaling pathway
Fc epsilon RI signaling pathway
TNF signaling pathway
GnRH signaling pathway
Relaxin signaling pathway
Chagas disease (American trypanosomiasis)
Hepatitis B
Influenza A
HTLV-I infection
Kaposi's sarcoma-associated herpesvirus infection
Epstein-Barr virus infection
Fluid shear stress and atherosclerosis
Module
MAPK (JNK) signaling
Brite
KEGG Orthology (KO) [BR:bta00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    526469 (MAP2K4)
   04012 ErbB signaling pathway
    526469 (MAP2K4)
   04668 TNF signaling pathway
    526469 (MAP2K4)
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    526469 (MAP2K4)
   04664 Fc epsilon RI signaling pathway
    526469 (MAP2K4)
  Endocrine system
   04912 GnRH signaling pathway
    526469 (MAP2K4)
   04926 Relaxin signaling pathway
    526469 (MAP2K4)
 Human Diseases
  Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    526469 (MAP2K4)
  Infectious diseases
   05166 HTLV-I infection
    526469 (MAP2K4)
   05164 Influenza A
    526469 (MAP2K4)
   05161 Hepatitis B
    526469 (MAP2K4)
   05167 Kaposi's sarcoma-associated herpesvirus infection
    526469 (MAP2K4)
   05169 Epstein-Barr virus infection
    526469 (MAP2K4)
   05142 Chagas disease (American trypanosomiasis)
    526469 (MAP2K4)
Enzymes [BR:bta01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     526469 (MAP2K4)
Protein kinases [BR:bta01001]
 Serine/threonine protein kinases: STE group
  STE7 family
   526469 (MAP2K4)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
BGD-bta: 
Ensembl: 
UniProt: 
Position
19
AA seq 412 aa AA seqDB search
MAAPSPSGGGGGGGGSGGGSGTPGPAGSPAPGHPAVSSMQGFQINFCEKAQSKRKALKLN
FANPPFKSTARFTLNPNPAGVQNPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGE
IGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGA
LFREGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIH
RDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVR
SDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLC
LTKDESKRPKYKELLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYVD
NT seq 1239 nt NT seq  +upstreamnt  +downstreamnt
atggcggctccgagccccagcggcggcggcggcggcggcggcggctccgggggcggcagc
ggcaccccgggccccgcggggtccccggcgcccggccacccggccgtcagcagcatgcag
ggctttcagataaacttctgtgaaaaggcacaaagtaaacgcaaagcactgaagttgaat
tttgcaaatccacctttcaaatctacagcaaggtttactctgaatcccaatcctgcagga
gttcaaaacccacacatagagagactgagaacacacagcattgagtcgtcaggaaaactg
aagatctcccctgagcagcactgggatttcactgcagaggatttgaaagaccttggagag
attggacgaggagcttacggttctgtcaacaaaatggtccacaaacccagtgggcaaata
atggcagttaaaagaatccggtcgacagtggatgaaaaagagcagaagcagctcctcatg
gatttggatgtagtgatgcggagcagtgactgcccatacattgttcagttctatggcgcg
ctcttccgagagggtgactgttggatctgcatggaactcatgtctacctcgtttgataag
ttttacaaatatgtatatagtgtattagatgatgttattccagaagaaattttaggcaaa
atcactttagcaactgtgaaagcactaaaccacttaaaagaaaacttgaaaatcattcac
agagatatcaaaccttccaatattcttctggatagaagtggaaatattaaactctgtgac
tttggcatcagtggacagctcgtggactcgatcgctaagacaagagatgctggctgcagg
ccctacatggcacctgaaagaatagacccaagtgcgtcacgccaaggctacgacgtccgc
tctgatgtctggagtctggggatcacattgtacgaattggccactggccgctttccttat
ccaaagtggaatagtgtatttgatcaactaacacaagtcgtgaaaggggatccgccacag
ctgagtaactctgaggaaagggagttctccccaagtttcatcaactttgtcaacttgtgc
cttacgaaggatgaatccaaaaggccaaagtataaagaactcctgaaacacccctttatt
ttgatgtacgaggagcgcgccgtcgaggtcgcatgctacgtgtgtaaaatcctggatcaa
atgccagccaccccgagctcccccatgtatgtcgattga

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