KEGG   Bos taurus (cow): 530001Help
Entry
530001            CDS       T01008                                 

Gene name
PIK3CG
Definition
phosphoinositide-3-kinase, catalytic, gamma polypeptide (EC:2.7.1.137)
Orthology
K00922  
phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
Organism
bta  Bos taurus (cow)
Pathway
Inositol phosphate metabolism
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phosphatidylinositol signaling system
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Apoptosis
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Osteoclast differentiation
Focal adhesion
Signaling pathways regulating pluripotency of stem cells
Platelet activation
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Cholinergic synapse
Inflammatory mediator regulation of TRP channels
Regulation of actin cytoskeleton
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Prolactin signaling pathway
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Type II diabetes mellitus
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Carbohydrate digestion and absorption
Bacterial invasion of epithelial cells
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Amoebiasis
Hepatitis C
Hepatitis B
Measles
Influenza A
HTLV-I infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Colorectal cancer
Renal cell carcinoma
Pancreatic cancer
Endometrial cancer
Glioma
Prostate cancer
Melanoma
Chronic myeloid leukemia
Acute myeloid leukemia
Small cell lung cancer
Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:bta00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    530001 (PIK3CG)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    530001 (PIK3CG)
   04015 Rap1 signaling pathway
    530001 (PIK3CG)
   04012 ErbB signaling pathway
    530001 (PIK3CG)
   04370 VEGF signaling pathway
    530001 (PIK3CG)
   04630 Jak-STAT signaling pathway
    530001 (PIK3CG)
   04668 TNF signaling pathway
    530001 (PIK3CG)
   04066 HIF-1 signaling pathway
    530001 (PIK3CG)
   04068 FoxO signaling pathway
    530001 (PIK3CG)
   04070 Phosphatidylinositol signaling system
    530001 (PIK3CG)
   04024 cAMP signaling pathway
    530001 (PIK3CG)
   04022 cGMP - PKG signaling pathway
    530001 (PIK3CG)
   04151 PI3K-Akt signaling pathway
    530001 (PIK3CG)
   04152 AMPK signaling pathway
    530001 (PIK3CG)
   04150 mTOR signaling pathway
    530001 (PIK3CG)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    530001 (PIK3CG)
  Cell growth and death
   04210 Apoptosis
    530001 (PIK3CG)
  Cellular commiunity
   04510 Focal adhesion
    530001 (PIK3CG)
   04550 Signaling pathways regulating pluripotency of stem cells
    530001 (PIK3CG)
 Organismal Systems
  Immune system
   04611 Platelet activation
    530001 (PIK3CG)
   04620 Toll-like receptor signaling pathway
    530001 (PIK3CG)
   04650 Natural killer cell mediated cytotoxicity
    530001 (PIK3CG)
   04660 T cell receptor signaling pathway
    530001 (PIK3CG)
   04662 B cell receptor signaling pathway
    530001 (PIK3CG)
   04664 Fc epsilon RI signaling pathway
    530001 (PIK3CG)
   04666 Fc gamma R-mediated phagocytosis
    530001 (PIK3CG)
   04670 Leukocyte transendothelial migration
    530001 (PIK3CG)
   04062 Chemokine signaling pathway
    530001 (PIK3CG)
  Endocrine system
   04910 Insulin signaling pathway
    530001 (PIK3CG)
   04915 Estrogen signaling pathway
    530001 (PIK3CG)
   04914 Progesterone-mediated oocyte maturation
    530001 (PIK3CG)
   04917 Prolactin signaling pathway
    530001 (PIK3CG)
   04921 Oxytocin signaling pathway
    530001 (PIK3CG)
   04919 Thyroid hormone signaling pathway
    530001 (PIK3CG)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    530001 (PIK3CG)
  Digestive system
   04973 Carbohydrate digestion and absorption
    530001 (PIK3CG)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    530001 (PIK3CG)
  Nervous system
   04725 Cholinergic synapse
    530001 (PIK3CG)
   04722 Neurotrophin signaling pathway
    530001 (PIK3CG)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    530001 (PIK3CG)
  Development
   04380 Osteoclast differentiation
    530001 (PIK3CG)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    530001 (PIK3CG)
   05205 Proteoglycans in cancer
    530001 (PIK3CG)
   05203 Viral carcinogenesis
    530001 (PIK3CG)
   05210 Colorectal cancer
    530001 (PIK3CG)
   05212 Pancreatic cancer
    530001 (PIK3CG)
   05214 Glioma
    530001 (PIK3CG)
   05221 Acute myeloid leukemia
    530001 (PIK3CG)
   05220 Chronic myeloid leukemia
    530001 (PIK3CG)
   05218 Melanoma
    530001 (PIK3CG)
   05211 Renal cell carcinoma
    530001 (PIK3CG)
   05215 Prostate cancer
    530001 (PIK3CG)
   05213 Endometrial cancer
    530001 (PIK3CG)
   05222 Small cell lung cancer
    530001 (PIK3CG)
   05223 Non-small cell lung cancer
    530001 (PIK3CG)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    530001 (PIK3CG)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    530001 (PIK3CG)
  Infectious diseases
   05100 Bacterial invasion of epithelial cells
    530001 (PIK3CG)
   05166 HTLV-I infection
    530001 (PIK3CG)
   05162 Measles
    530001 (PIK3CG)
   05164 Influenza A
    530001 (PIK3CG)
   05161 Hepatitis B
    530001 (PIK3CG)
   05160 Hepatitis C
    530001 (PIK3CG)
   05169 Epstein-Barr virus infection
    530001 (PIK3CG)
   05146 Amoebiasis
    530001 (PIK3CG)
   05145 Toxoplasmosis
    530001 (PIK3CG)
   05142 Chagas disease (American trypanosomiasis)
    530001 (PIK3CG)
Enzymes [BR:bta01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     530001 (PIK3CG)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
BGD-bta: 
Ensembl: 
UniProt: 
Position
4
AA seq 885 aa AA seqDB search
MELENHEQPVVLREDNCRRRRRMKPRSTAASMSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRVLETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLHYWKVLHRSPGQIHLVQRHSPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIIIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKASAETPSPESRGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLRDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVIFQLKQKLEILQNLNLP
QSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGNHQHEPGK
NT seq 2658 nt NT seq  +upstreamnt  +downstreamnt
atggagctggagaaccatgaacagcctgtggtgctgagagaggacaactgccgcaggcgc
cggaggatgaagccacgcagcacggcggccagcatgtcctccatggagctcatccccatt
gagttcgtgctgcccaccagccaacgcaacaccaagacccccgaaacggcgctgctgcac
gtggccggccacggcaacgtggagcagatgaaggcccaagtgtggctgcgcgtgctggag
accagcgtggccgccgacttctaccacaggctgggcccggaccacttcctcctgctctac
cagaagaaggggcagtggtatgagatctatgacaagtaccaggtggtgcagaccctggac
tgcctgcactactggaaggtgctgcaccggagccccgggcagatccacctggtacagcgg
cactcgccctcagaggagacgctggccttccagcgccagctcactgccctcatcggctac
gatgtcacagatgtcagcaatgtgcacgacgacgagttggagttcacacgccgccgcctg
gtcaccccgcgtatggccgaggtggctggccgcgaccccaagctctacgccatgcacccc
tgggtgacgtctaagcccctccctgagtacctgctgaagaagatcaccaacaactgtatc
ttcatcattattcaccgcagcaccaccagccagaccatcaaggtctcggctgatgatacc
cctggcaccatcctccagagcttctttaccaaaatggccaagaagaagtccctgatggat
atccccgagagccagaacgaacaggactttgtgctgcgtgtctgtggccgcgatgagtac
ctggtgggcgagacgcccatcaaaaactttcagtgggtgcggcagtgccttaagaatggt
gaagagattcacctggtgcttgacactccgccggacccagccctggatgaggtgaggaag
gaagagtggccgctggtggatgactgcactggagtcactggctaccatgagcagctaacc
atccatgggaaggaccatgagagcgtgttcactgtgtccctgtgggactgtgaccgcaag
ttcagagtcaagatcaggggcatcgatatccccgtcctgccccggaatgcagatctcacg
gtttttgtggaggcaaacatccagtatgggcagcaagtcctttgccaaagaagaaccagc
ccaaaacccttcacggaggaggtgctctggaatgtgtggcttgagttcagtatcaagatc
aaagacttacccaaaggggctctgctcaacctccagatctactgtggcaaagcaccagct
ctgtctggtaaggcctctgcagagactcccagtcccgagtccagaggcaaagctcagctt
ctctactacgtgaacttgctgctcatcgaccaccgattcctcctgcgccacggcgagtac
gtgctccacatgtggcagttatctgggaagggggaagaccaagggagcttcaatgcagac
aagctcacatctgccaccaatcccgacaaggaaaactcaatgtccatctccattctcctg
gacaactactgtcaccccatagccttgcctaagcatcagcccacccctgacccggaaggg
gaccgcgtacgagcagaaatgcccaaccaacttcggaagcaactggaggcaatcatagct
actgatccacttaaccctcttactgcggaagacaaagaattgctttggcatttcagatat
gaaagccttaaggatcccaaagcataccctaagctctttagctcagtgaaatggggacag
caagaaattgtggccaaaacatatcaattgttagccagaagggaggtctgggatcaaagt
gctttggatgttggattaacgatgcaactcctagactgcaacttttcggatgaaaacgta
agagccattgcagttcagaaactggagagcttggaagacgatgacgttctgcattacctg
ctccaattggtccaggctgtgaaatttgaaccataccatgacagtgcccttgccagattt
ctgctgaagcgtggtttaagaaacaaaagaattggtcacttcttgttttggttcttgaga
agtgagattgcccagtcgagacactatcagcagaggtttgcagtgatcctggaggcctac
ctgaggggctgtggtacggccatgctacgggacttcactcaacaagtccaagtaattgac
atgttacaaaaagtcaccattgatattaaatcactctctgccgaaaagtatgacgtcagc
tcccaagttattttccaactaaagcaaaagcttgaaatcctgcagaatttgaatctcccc
caaagctttagagttccatatgaccctggactgaaggcaggcgcactggtgattgaaaaa
tgtaaagtgatggcctctaagaaaaaacctctgtggcttgagtttaaatgtgctgaccct
acagctctatcaaatgaaacaattggaattatctttaaacacggtgatgatctgcgccaa
gacatgcttattctacagattctacgaatcatggagtccatttgggagactgaatctttg
gatctgtgcctcctgccatatggttgcatttcaactggtgacaaaataggaaaccaccag
cacgaacctggaaaataa

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