KEGG   Bos taurus (cow): 538954Help
Entry
538954            CDS       T01008                                 

Gene name
PRKAA2
Definition
protein kinase, AMP-activated, alpha 2 catalytic subunit
Orthology
K07198  
5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
Organism
bta  Bos taurus (cow)
Pathway
FoxO signaling pathway
Regulation of autophagy
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Circadian rhythm
Insulin signaling pathway
Adipocytokine signaling pathway
Oxytocin signaling pathway
Non-alcoholic fatty liver disease (NAFLD)
Hypertrophic cardiomyopathy (HCM)
Brite
KEGG Orthology (KO) [BR:bta00001]
 Environmental Information Processing
  Signal transduction
   04068 FoxO signaling pathway
    538954 (PRKAA2)
   04151 PI3K-Akt signaling pathway
    538954 (PRKAA2)
   04152 AMPK signaling pathway
    538954 (PRKAA2)
   04150 mTOR signaling pathway
    538954 (PRKAA2)
 Cellular Processes
  Transport and catabolism
   04140 Regulation of autophagy
    538954 (PRKAA2)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    538954 (PRKAA2)
   04920 Adipocytokine signaling pathway
    538954 (PRKAA2)
   04921 Oxytocin signaling pathway
    538954 (PRKAA2)
  Environmental adaptation
   04710 Circadian rhythm
    538954 (PRKAA2)
 Human Diseases
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    538954 (PRKAA2)
  Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    538954 (PRKAA2)
Enzymes [BR:bta01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     538954 (PRKAA2)
Protein kinases [BR:bta01001]
 Serine/threonine protein kinases: CAMK group
  CAMKL family
   538954 (PRKAA2)
Mitochondrial biogenesis [BR:bta03029]
 Mitochondrial quality control factors
  Regulator of mitochondrial biogenesis
   Other regulator of mitochondrial biogenesis
    538954 (PRKAA2)
  Mitophagy factors
   Other mitophagy factors
    538954 (PRKAA2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
BGD-bta: 
Ensembl: 
Position
3
AA seq 552 aa AA seqDB search
MAEKQKHDGRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGK
IKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLF
QQILSAVDYCHRHMVVHRDLKPENVLLDAQMNAKIADFGLSNMMSDGEFLRTSCGSPNYA
APEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRS
VATLLMHMLQVDPLKRATIKDIREHEWFKQDLPSYLFPEDPSYDANVIDDEAVKEVCEKF
ECTESEVMNSLYSGDPQDQLAVAYHLIIDNRRIMNQASEFYLASSPPTGSFMDDSTMHIP
PGLKPHPERMPPLIADSPKARCPLDALNTTKPKSLAVKKAKWHLGIRSQSKPYDIMAEVY
RAMKQLDFEWKVVNAYHLRVRRRNPVTGNYVKMSLQLYLVDNRSYLLDFKSIDDEVVEQR
SGSSTPQRSCSAAGLHRPRSSLDSVTAEGHSLSGSLTGSLTGSMSSSVSPRLGSHTMDFF
EMCASLITTLAR
NT seq 1659 nt NT seq  +upstreamnt  +downstreamnt
atggctgagaagcagaagcacgacgggcgggtgaagatcggccactacgtgctgggcgac
acgctgggcgtcggcaccttcggcaaagtgaagattggagagcatcaattgacaggccat
aaagttgcagttaaaattttaaatagacagaagattcgcagtttagatgttgttggaaaa
ataaaacgagaaattcaaaatctaaaactctttcgtcatcctcatattatcaaactatac
caggtgatcagcactccaacagatttttttatggtaatggaatatgtgtctggtggtgaa
ttgtttgactacatctgtaaacatggacgggttgaagagatggaagctcggcggctgttt
cagcagattctgtctgccgtggattactgtcacaggcacatggttgttcatcgagacctg
aaaccagagaatgtgctattggacgcacagatgaatgccaagatagctgattttggatta
tctaacatgatgtcagatggtgaatttctgcgaactagctgcggatccccaaattatgca
gcacctgaagtcatctcaggcaggctgtatgcaggtcctgaagtggatatctggagctgc
ggtgttattttgtatgctcttctttgtggcaccctcccatttgatgatgagcatgtgcct
acgctgtttaagaagatccgagggggtgttttttacatcccagaatatctcaatcgttct
gttgctactctcctgatgcatatgctgcaggttgatcccctgaaacgagcaactatcaaa
gacataagagagcatgaatggtttaaacaagatttgcccagttacttatttcctgaagac
ccctcctatgatgctaacgtcattgatgatgaggctgtgaaagaagtgtgtgaaaaattt
gagtgtacagaatcagaagtaatgaacagtttatatagtggtgaccctcaagaccagctt
gcagtggcttatcatcttatcattgacaatcggagaataatgaaccaagccagtgagttc
tacctcgcctctagtcccccaactggttcttttatggatgatagtaccatgcatattccc
ccaggcctgaaacctcatccggaaaggatgccacctcttatagcagacagccctaaagca
cgatgtccactggatgcactgaatacaacgaagcccaaatctttagctgtgaaaaaagcc
aagtggcatcttggaatccgaagtcaaagcaaaccatatgacattatggctgaagtttac
cgagctatgaagcagctggattttgaatggaaggtagtgaatgcataccatctacgtgta
agaagaagaaatccagtgactggcaattatgtgaaaatgagcttacagctgtacctggtt
gacaacagaagctatcttttggactttaaaagcattgatgatgaggtggtggagcagagg
tctggttcctcaacacctcagcggtcctgttctgctgctggcttacacagaccacggtcc
agtttggattctgtaactgcggagggccattcactctctggctctctcacgggctctttg
accggaagcatgtcgtcctctgtctcacctcgcctgggcagtcacaccatggattttttt
gaaatgtgtgccagtctgatcactactttagcacgctga

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