KEGG   Bos taurus (cow): 539941Help
Entry
539941            CDS       T01008                                 

Gene name
MAPK8, JNK1
Definition
mitogen-activated protein kinase 8 (EC:2.7.11.24)
Orthology
K04440  
c-Jun N-terminal kinase [EC:2.7.11.24]
Organism
bta  Bos taurus (cow)
Pathway
MAPK signaling pathway
ErbB signaling pathway
Ras signaling pathway
FoxO signaling pathway
Protein processing in endoplasmic reticulum
Wnt signaling pathway
Osteoclast differentiation
Focal adhesion
Toll-like receptor signaling pathway
NOD-like receptor signaling pathway
RIG-I-like receptor signaling pathway
Fc epsilon RI signaling pathway
TNF signaling pathway
Neurotrophin signaling pathway
Retrograde endocannabinoid signaling
Dopaminergic synapse
Inflammatory mediator regulation of TRP channels
Insulin signaling pathway
GnRH signaling pathway
Progesterone-mediated oocyte maturation
Prolactin signaling pathway
Adipocytokine signaling pathway
Type II diabetes mellitus
Non-alcoholic fatty liver disease (NAFLD)
Salmonella infection
Pertussis
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Tuberculosis
Hepatitis C
Hepatitis B
Influenza A
Herpes simplex infection
Epstein-Barr virus infection
Pathways in cancer
Colorectal cancer
Pancreatic cancer
Brite
KEGG Orthology (KO) [BR:bta00001]
 Genetic Information Processing
  Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    539941 (MAPK8)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    539941 (MAPK8)
   04010 MAPK signaling pathway
    539941 (MAPK8)
   04012 ErbB signaling pathway
    539941 (MAPK8)
   04310 Wnt signaling pathway
    539941 (MAPK8)
   04668 TNF signaling pathway
    539941 (MAPK8)
   04068 FoxO signaling pathway
    539941 (MAPK8)
 Cellular Processes
  Cell communication
   04510 Focal adhesion
    539941 (MAPK8)
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    539941 (MAPK8)
   04621 NOD-like receptor signaling pathway
    539941 (MAPK8)
   04622 RIG-I-like receptor signaling pathway
    539941 (MAPK8)
   04664 Fc epsilon RI signaling pathway
    539941 (MAPK8)
  Endocrine system
   04910 Insulin signaling pathway
    539941 (MAPK8)
   04920 Adipocytokine signaling pathway
    539941 (MAPK8)
   04912 GnRH signaling pathway
    539941 (MAPK8)
   04914 Progesterone-mediated oocyte maturation
    539941 (MAPK8)
   04917 Prolactin signaling pathway
    539941 (MAPK8)
  Nervous system
   04728 Dopaminergic synapse
    539941 (MAPK8)
   04723 Retrograde endocannabinoid signaling
    539941 (MAPK8)
   04722 Neurotrophin signaling pathway
    539941 (MAPK8)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    539941 (MAPK8)
  Development
   04380 Osteoclast differentiation
    539941 (MAPK8)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    539941 (MAPK8)
   05210 Colorectal cancer
    539941 (MAPK8)
   05212 Pancreatic cancer
    539941 (MAPK8)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    539941 (MAPK8)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    539941 (MAPK8)
  Infectious diseases
   05132 Salmonella infection
    539941 (MAPK8)
   05133 Pertussis
    539941 (MAPK8)
   05152 Tuberculosis
    539941 (MAPK8)
   05164 Influenza A
    539941 (MAPK8)
   05161 Hepatitis B
    539941 (MAPK8)
   05160 Hepatitis C
    539941 (MAPK8)
   05168 Herpes simplex infection
    539941 (MAPK8)
   05169 Epstein-Barr virus infection
    539941 (MAPK8)
   05145 Toxoplasmosis
    539941 (MAPK8)
   05142 Chagas disease (American trypanosomiasis)
    539941 (MAPK8)
Enzymes [BR:bta01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     539941 (MAPK8)
Protein kinases [BR:bta01001]
 Serine/threonine protein kinases: CMGC group
  MAPK family [Table]
   539941 (MAPK8)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
BGD-bta: 
Ensembl: 
UniProt: 
Position
28
AA seq 384 aa AA seqDB search
MSRSKRDSNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQ
LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSR
MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV
MDLEERTKNGVIRGQPSPLAQVQQ
NT seq 1155 nt NT seq  +upstreamnt  +downstreamnt
atgagcagaagcaagcgtgacagcaatttttatagtgtagagattggagattctacattc
acagtcctgaaacggtatcagaatttaaaacctataggttcaggagcccaaggaatagta
tgtgcagcttatgatgccattcttgaaagaaacgttgcaatcaagaagttaagtcggcca
tttcagaatcaaactcatgctaagcgtgcttacagagagctagttctcatgaaatgtgta
aatcacaaaaatataattggccttttgaatgtttttacaccacagaaatccctagaagaa
tttcaagatgtttacatagtcatggagctcatggatgcaaatctttgtcaagtgattcag
atggagctagatcatgaaagaatgtcctacctgctctatcagatgctgtgtgggatcaag
caccttcactctgctggaattattcaccgggacttaaagcccagtaatatagtagtaaaa
tcagactgcactttgaagattcttgactttggactggccaggactgcaggaactagtttt
atgatgacaccttacgtagtgactcgctactacagagcacctgaggtcatcctaggcatg
ggctacaaagaaaacgttgacatttggtcagttgggtgcatcatgggagaaatgatcaaa
ggtggtgttttgttcccaggtacagatcatattgatcagtggaataaagttattgaacag
cttggaacaccatgtcctgaattcatgaagaaactacaaccaacagtaaggacttatgtt
gaaaacagacctaaatatgccggatatagctttgagaaactcttccctgatgtacttttc
ccagctgactcggaacacaacaaacttaaagccagtcaggcaagggatttgttatccaga
atgctggtaatcgacgcatctaaaaggatttctgtagacgaagctctccagcacccgtat
atcaatgtctggtatgacccttctgaagcagaagctccaccaccaaagatacctgacaag
cagttagatgaaagggaacacacaatagaagagtggaaagaattgatatacaaagaagtt
atggacttggaggagagaaccaagaatggagttatacgggggcagccctctcctttagca
caggtgcagcagtga

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