KEGG   Bos taurus (cow): 540404Help
Entry
540404            CDS       T01008                                 

Gene name
PRKAA1
Definition
(RefSeq) protein kinase AMP-activated catalytic subunit alpha 1
  KO
K07198  5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
Organism
bta  Bos taurus (cow)
Pathway
bta04068  FoxO signaling pathway
bta04140  Autophagy - animal
bta04150  mTOR signaling pathway
bta04151  PI3K-Akt signaling pathway
bta04152  AMPK signaling pathway
bta04211  Longevity regulating pathway
bta04213  Longevity regulating pathway - multiple species
bta04371  Apelin signaling pathway
bta04530  Tight junction
bta04710  Circadian rhythm
bta04714  Thermogenesis
bta04910  Insulin signaling pathway
bta04920  Adipocytokine signaling pathway
bta04921  Oxytocin signaling pathway
bta04922  Glucagon signaling pathway
bta04931  Insulin resistance
bta04932  Non-alcoholic fatty liver disease (NAFLD)
bta05410  Hypertrophic cardiomyopathy (HCM)
bta05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:bta00001]
 Environmental Information Processing
  Signal transduction
   04371 Apelin signaling pathway
    540404 (PRKAA1)
   04068 FoxO signaling pathway
    540404 (PRKAA1)
   04151 PI3K-Akt signaling pathway
    540404 (PRKAA1)
   04152 AMPK signaling pathway
    540404 (PRKAA1)
   04150 mTOR signaling pathway
    540404 (PRKAA1)
 Cellular Processes
  Transport and catabolism
   04140 Autophagy - animal
    540404 (PRKAA1)
  Cellular community - eukaryotes
   04530 Tight junction
    540404 (PRKAA1)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    540404 (PRKAA1)
   04922 Glucagon signaling pathway
    540404 (PRKAA1)
   04920 Adipocytokine signaling pathway
    540404 (PRKAA1)
   04921 Oxytocin signaling pathway
    540404 (PRKAA1)
  Aging
   04211 Longevity regulating pathway - mammal
    540404 (PRKAA1)
   04213 Longevity regulating pathway - multiple species
    540404 (PRKAA1)
  Environmental adaptation
   04710 Circadian rhythm
    540404 (PRKAA1)
   04714 Thermogenesis
    540404 (PRKAA1)
 Human Diseases
  Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    540404 (PRKAA1)
   05410 Hypertrophic cardiomyopathy (HCM)
    540404 (PRKAA1)
  Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    540404 (PRKAA1)
   04931 Insulin resistance
    540404 (PRKAA1)
Enzymes [BR:bta01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     540404 (PRKAA1)
Protein kinases [BR:bta01001]
 Serine/threonine kinases: CAMK group
  CAMKL family
   540404 (PRKAA1)
Membrane trafficking [BR:bta04131]
 Autophagy
  Other autophagy associated proteins
   Others
    540404 (PRKAA1)
Mitochondrial biogenesis [BR:bta03029]
 Mitochondrial quality control factors
  Regulator of mitochondrial biogenesis
   Other regulator of mitochondrial biogenesis
    540404 (PRKAA1)
  Mitophagy factors
   Other mitophagy factors
    540404 (PRKAA1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Pkinase Pkinase_Tyr AdenylateSensor Kinase-like Kdo APH RIO1 Haspin_kinase
Motif
Other DBs
NCBI-GeneID: 540404
NCBI-ProteinID: NP_001103272
Ensembl: ENSBTAG00000000013
UniProt: A8E649
Position
20
AA seq 458 aa AA seqDB search
MVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAH
MNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCG
TLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWFKQ
DLPKYLFPEDPSYSSTMIDDEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLIIDN
RRIMNEAKDFYLATSPPDSFLDDHHLTRPHPERVPFLVAETPRARHTLDELNPQKSKHQG
VRKAKWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQ
LYQVDSRTYLLDFRSIDDEITEAKSGTATPQRSGSVSNYRACQRNDSDAEAQGKSSEASL
TSSVTSLDSSPVELTPRPGSHTIEFFEMCANLIKILAQ
NT seq 1377 nt NT seq  +upstreamnt  +downstreamnt
atggtgatggaatatgtctcaggaggagagctatttgattatatctgtaaaaatggaagg
ctggatgaaaaagaaagtcgacgactgttccaacaaatcctttctggtgtggattactgt
cacaggcatatggtggtccacagagatttgaaacctgaaaacgtcctgcttgatgcacac
atgaatgcaaagatagctgattttggtctttcaaacatgatgtcagatggtgaattttta
agaacaagttgtggctcacccaactatgctgcaccagaagtaatttcaggaagattgtat
gctggtccagaggtagatatatggagcagtggggttattctgtatgctttattatgtgga
acccttccgtttgatgatgatcacgtgccaactctttttaagaagatatgtgatgggatc
ttttatacccctcaatatttaaatccttctgtgattagccttttgaaacatatgctgcag
gtggatcccatgaagagagccacaatcaaagatatcagggaacatgaatggtttaaacag
gaccttccaaaatatctctttcctgaggatccatcatatagctcaaccatgattgatgat
gaagccttaaaagaagtatgtgaaaaatttgaatgctcagaggaggaggttctcagctgc
ctttataacagaaatcaccaggaccctttggcagttgcctaccacctcataatagataac
aggaggataatgaacgaggccaaagatttttacttggcaacgagcccaccagattcgttt
ctcgacgatcaccacttgactcggccccatcctgaaagagtaccattcttggttgctgaa
actcccagggcgcgccatacccttgatgaattaaatccacagaaatccaaacaccaaggt
gtaaggaaagcaaaatggcatttgggaattagaagtcaaagtcggccaaatgatatcatg
gcagaagtttgtagagcaattaaacagctggattatgaatggaaggttgtaaacccgtat
tatttgcgtgttcggaggaagaatcctgtgacaagtacatactccaaaatgagtctgcag
ttataccaagtggatagtagaacgtatttactggatttccgaagtattgatgatgaaatt
actgaagccaaatcagggactgctacgccacagagatcgggctcagttagcaactatcga
gcttgccaaaggaatgattcagatgctgaggctcaaggaaaatcctcagaagcttctctt
acctcatctgtaacctcacttgactcttctcctgttgaattaactccaagacctggaagt
cacacaatagaattttttgagatgtgcgcgaatctaattaaaattcttgcacagtaa

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