KEGG   Bos taurus (cow): 540404Help
Entry
540404            CDS       T01008                                 

Gene name
PRKAA1
Definition
protein kinase, AMP-activated, alpha 1 catalytic subunit (EC:2.7.1.-)
Orthology
K07198  
5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
Organism
bta  Bos taurus (cow)
Pathway
FoxO signaling pathway
Regulation of autophagy
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Circadian rhythm
Insulin signaling pathway
Adipocytokine signaling pathway
Oxytocin signaling pathway
Non-alcoholic fatty liver disease (NAFLD)
Hypertrophic cardiomyopathy (HCM)
Brite
KEGG Orthology (KO) [BR:bta00001]
 Environmental Information Processing
  Signal transduction
   04068 FoxO signaling pathway
    540404 (PRKAA1)
   04151 PI3K-Akt signaling pathway
    540404 (PRKAA1)
   04152 AMPK signaling pathway
    540404 (PRKAA1)
   04150 mTOR signaling pathway
    540404 (PRKAA1)
 Cellular Processes
  Transport and catabolism
   04140 Regulation of autophagy
    540404 (PRKAA1)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    540404 (PRKAA1)
   04920 Adipocytokine signaling pathway
    540404 (PRKAA1)
   04921 Oxytocin signaling pathway
    540404 (PRKAA1)
  Environmental adaptation
   04710 Circadian rhythm
    540404 (PRKAA1)
 Human Diseases
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    540404 (PRKAA1)
  Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    540404 (PRKAA1)
Enzymes [BR:bta01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     540404 (PRKAA1)
Protein kinases [BR:bta01001]
 Serine/threonine protein kinases: CAMK group
  CAMKL family
   540404 (PRKAA1)
Mitochondrial biogenesis [BR:bta03029]
 Mitochondrial quality control factors
  Regulator of mitochondrial biogenesis
   Other regulator of mitochondrial biogenesis
    540404 (PRKAA1)
  Mitophagy factors
   Other mitophagy factors
    540404 (PRKAA1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
20
AA seq 458 aa AA seqDB search
MVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAH
MNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCG
TLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWFKQ
DLPKYLFPEDPSYSSTMIDDEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLIIDN
RRIMNEAKDFYLATSPPDSFLDDHHLTRPHPERVPFLVAETPRARHTLDELNPQKSKHQG
VRKAKWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQ
LYQVDSRTYLLDFRSIDDEITEAKSGTATPQRSGSVSNYRACQRNDSDAEAQGKSSEASL
TSSVTSLDSSPVELTPRPGSHTIEFFEMCANLIKILAQ
NT seq 1377 nt NT seq  +upstreamnt  +downstreamnt
atggtgatggaatatgtctcaggaggagagctatttgattatatctgtaaaaatggaagg
ctggatgaaaaagaaagtcgacgactgttccaacaaatcctttctggtgtggattactgt
cacaggcatatggtggtccacagagatttgaaacctgaaaacgtcctgcttgatgcacac
atgaatgcaaagatagctgattttggtctttcaaacatgatgtcagatggtgaattttta
agaacaagttgtggctcacccaactatgctgcaccagaagtaatttcaggaagattgtat
gctggtccagaggtagatatatggagcagtggggttattctgtatgctttattatgtgga
acccttccgtttgatgatgatcacgtgccaactctttttaagaagatatgtgatgggatc
ttttatacccctcaatatttaaatccttctgtgattagccttttgaaacatatgctgcag
gtggatcccatgaagagagccacaatcaaagatatcagggaacatgaatggtttaaacag
gaccttccaaaatatctctttcctgaggatccatcatatagctcaaccatgattgatgat
gaagccttaaaagaagtatgtgaaaaatttgaatgctcagaggaggaggttctcagctgc
ctttataacagaaatcaccaggaccctttggcagttgcctaccacctcataatagataac
aggaggataatgaacgaggccaaagatttttacttggcaacgagcccaccagattcgttt
ctcgacgatcaccacttgactcggccccatcctgaaagagtaccattcttggttgctgaa
actcccagggcgcgccatacccttgatgaattaaatccacagaaatccaaacaccaaggt
gtaaggaaagcaaaatggcatttgggaattagaagtcaaagtcggccaaatgatatcatg
gcagaagtttgtagagcaattaaacagctggattatgaatggaaggttgtaaacccgtat
tatttgcgtgttcggaggaagaatcctgtgacaagtacatactccaaaatgagtctgcag
ttataccaagtggatagtagaacgtatttactggatttccgaagtattgatgatgaaatt
actgaagccaaatcagggactgctacgccacagagatcgggctcagttagcaactatcga
gcttgccaaaggaatgattcagatgctgaggctcaaggaaaatcctcagaagcttctctt
acctcatctgtaacctcacttgactcttctcctgttgaattaactccaagacctggaagt
cacacaatagaattttttgagatgtgcgcgaatctaattaaaattcttgcacagtaa

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