KEGG   Bos taurus (cow): 616576Help
Entry
616576            CDS       T01008                                 

Gene name
GCK
Definition
glucokinase (hexokinase 4) (EC:2.7.1.2)
Orthology
K12407  
glucokinase [EC:2.7.1.2]
Organism
bta  Bos taurus (cow)
Pathway
Glycolysis / Gluconeogenesis
Galactose metabolism
Starch and sucrose metabolism
Amino sugar and nucleotide sugar metabolism
Butirosin and neomycin biosynthesis
Metabolic pathways
Carbon metabolism
Insulin signaling pathway
Insulin secretion
Prolactin signaling pathway
Type II diabetes mellitus
Maturity onset diabetes of the young
Module
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
Nucleotide sugar biosynthesis, glucose => UDP-glucose
Brite
KEGG Orthology (KO) [BR:bta00001]
 Metabolism
  Overview
   01200 Carbon metabolism
    616576 (GCK)
  Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    616576 (GCK)
   00052 Galactose metabolism
    616576 (GCK)
   00500 Starch and sucrose metabolism
    616576 (GCK)
   00520 Amino sugar and nucleotide sugar metabolism
    616576 (GCK)
  Biosynthesis of other secondary metabolites
   00524 Butirosin and neomycin biosynthesis
    616576 (GCK)
 Organismal Systems
  Endocrine system
   04911 Insulin secretion
    616576 (GCK)
   04910 Insulin signaling pathway
    616576 (GCK)
   04917 Prolactin signaling pathway
    616576 (GCK)
 Human Diseases
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    616576 (GCK)
   04950 Maturity onset diabetes of the young
    616576 (GCK)
Enzymes [BR:bta01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.2  glucokinase
     616576 (GCK)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
BGD-bta: 
Ensembl: 
UniProt: 
Position
4
AA seq 465 aa AA seqDB search
MLDDRARMEISKKEKAEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHKEASVKMLPT
YVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEAGQWSVKTTHQMYSIPEDAMTGTAE
MLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNN
IVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDRRCEVGMIVGTGCNACYMEEMQN
VELVEGDEGRMCVNTEWGAFGDSGELDEFLLEYDRVVDENSLNPGQQLYEKLIGGKYMGE
LVRLVLLKLVDENLLFHGEASEQLRTRGAFETRFVSQVESDSGDRKQIYNILSTLGLRPS
ATDCDIVRRACESVSTRAAHMCAAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFK
ERFHAIVRRLTPSCEITFIESEEGSGRGAALISAVACKKACMLGQ
NT seq 1398 nt NT seq  +upstreamnt  +downstreamnt
atgctggatgacagagccaggatggagatctccaagaaggaaaaggcggaacagatcctg
gcagagttccagctgcaggaggaggacttgaagaaggtgatgaggcggatgcagaaggag
atggaccgaggcctgaggctggagacccacaaggaggccagtgtgaagatgctgcccacc
tatgtgcgctccaccccagagggctcagaagttggggacttcctctccctggacctgggt
ggcaccaacttccgggtgatgctggtgaaggtgggagaaggcgaggcgggacagtggagt
gtgaagaccacgcaccagatgtactccatccccgaggatgccatgacgggtactgctgag
atgctctttgactacatctctgagtgcatctctgacttcctggataagcatcagatgaag
cataagaagctgcccttgggcttcaccttctcctttcccgtgaggcatgaagacattgac
aagggcatccttctcaactggaccaagggcttcaaggcctcgggagcagaaggcaacaac
attgtggggctcctgcgagatgccatcaagcggagaggtgactttgagatggacgtggtg
gccatggtgaatgacactgtggccacgatgatctcctgctactatgaagaccgccggtgt
gaggttggcatgattgtgggcacgggctgcaacgcttgctacatggaggagatgcagaac
gtggagctggtggaaggggacgagggccgcatgtgtgtcaacaccgagtggggcgccttc
ggggactcaggcgagctggacgagttcctgctggagtacgaccgcgtggtggatgagaac
tccctgaaccctggccagcagctgtacgagaaactcatcggtggcaagtacatgggcgag
ctggtgcggcttgtgctgctgaagcttgtggacgagaatctgctcttccacggagaggcc
tcggagcagctgcgcacgcgcggcgccttcgagacacgcttcgtgtctcaggtggagagc
gattccggtgaccgcaagcagatctacaatatcctgagcactctagggctgcgaccctcg
gccactgactgtgacatcgtgcgccgagcctgcgagagcgtgtccacgcgcgccgcgcac
atgtgcgccgcgggactggcgggcgtcatcaaccggatgcgcgaaagccgcagcgaggac
gtgatgcgcatcaccgtgggcgtggacggctccgtgtacaagctgcaccctagcttcaag
gagcggttccacgccatcgtgcgcaggctgacgcccagctgtgaaatcaccttcattgag
tcggaggagggcagcggccggggcgcggccttgatctccgcggtggcctgtaagaaggcc
tgcatgctgggccagtaa

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