KEGG   Bos taurus (cow): 512312
Entry
512312            CDS       T01008                                 
Symbol
PTPN6
Name
(RefSeq) tyrosine-protein phosphatase non-receptor type 6
  KO
K05697  tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
Organism
bta  Bos taurus (cow)
Pathway
bta04148  Efferocytosis
bta04520  Adherens junction
bta04630  JAK-STAT signaling pathway
bta04650  Natural killer cell mediated cytotoxicity
bta04660  T cell receptor signaling pathway
bta04662  B cell receptor signaling pathway
bta05140  Leishmaniasis
bta05205  Proteoglycans in cancer
bta05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:bta00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    512312 (PTPN6)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    512312 (PTPN6)
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    512312 (PTPN6)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    512312 (PTPN6)
   04660 T cell receptor signaling pathway
    512312 (PTPN6)
   04662 B cell receptor signaling pathway
    512312 (PTPN6)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    512312 (PTPN6)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    512312 (PTPN6)
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    512312 (PTPN6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:bta01009]
    512312 (PTPN6)
Enzymes [BR:bta01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     512312 (PTPN6)
Protein phosphatases and associated proteins [BR:bta01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Classical)
   Non-receptor PTPs
    512312 (PTPN6)
SSDB
Motif
Pfam: Y_phosphatase SH2 DSPc PTPlike_phytase Y_phosphatase3 HGAL
Other DBs
NCBI-GeneID: 512312
NCBI-ProteinID: NP_001091486
BGD-bta: BT17336
Ensembl: ENSBTAG00000020294
VGNC: 33541
UniProt: A5D980
Position
5:complement(103502500..103518190)
AA seq 593 aa
MVRWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGDF
YDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGGQA
ETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTHIKVMCEGGRYTVGG
SETFDSLTDLVEHFKRTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESEETA
KAGFWEEFESLQKQEVKNLHQRLEGQRPENKSKNRYKNILPFDHSRVVLQGRDSNIPGSD
YINANYVKNQLLGPDENAKTYIASQGCLEATVNDFWQMVWQENTCVIVMTTREVEKGRNK
CVPYWPEVGSQRVYGPYTVTNCGEHDTTEYKLRNLQVSPLENENLIREIWHYQYLSWPDH
GVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMESISTKGLDC
DIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVMQSQKGRESEYGNIT
YPPAMKNAHAKASRTSSKEDVYENVHSKNKKEEKVKKQRSADKEKNKGSLKRK
NT seq 1782 nt   +upstreamnt  +downstreamnt
atggtgaggtggtttcaccgagacctcagtgggctggatgcggagaccctgctcaagggc
cgaggggtccacggaagcttcctggcacggcccagccgcaagaaccagggtgacttctcc
ctctccgtcagggttggggaccaggtgactcatattcggatccagaactctggggacttc
tacgatctgtatggaggggagaagttcgcaacgttgacggagctggtggagtactacacg
cagcagcagggtgttctacaggaccgagacggcactatcatccacctcaagtacccgctg
aactgctcagaccccaccagtgagaggtggtaccatggccacatgtctggagggcaggca
gagactttgctgcaggccaagggggagccttggactttccttgtgcgtgagagcctcagc
cagcctggagattttgtgctgtccgtgctcagcgaccagcccaaggctggccccggctcc
ccgctcagagtcacccatatcaaagtcatgtgtgagggcggacgctacacagtggggggt
tcggagaccttcgacagcctcactgacctggtggagcatttcaagaggacggggatcgag
gaggcctccggcgctttcgtctacctacggcagccatactatgccacgagggtgaacgcg
gctgacattgagaaccgggtcttggaactgaacaagaagcaggagtcagaggagacagcc
aaggccggcttctgggaggagtttgagagtctgcagaagcaggaggtgaaaaacttgcac
cagcggctggaagggcagcggccagaaaacaagagcaagaaccgttacaagaacatcctt
ccgtttgaccacagtcgagtggtcctgcagggacgcgacagtaacatccctgggtctgac
tacattaacgccaactatgtgaagaaccagctgctaggccctgatgagaacgctaagacc
tacatcgccagccagggctgcctggaggccacggtcaacgacttttggcagatggtgtgg
caggagaacacctgcgtcattgtcatgaccacccgggaggtggagaagggccggaacaaa
tgtgttccatactggccagaagtgggcagtcagcgtgtttacggaccctacaccgtaacc
aattgcggggaacacgacacaactgagtacaaactccgaaacttacaggtctccccgctg
gaaaatgagaacctgattcgggagatttggcactaccagtacctgagctggcctgatcac
ggggtccccagtgagcctgggggtgttctcagcttcctggaccagatcaaccagcggcag
gagagtctgcctcacgcagggcccatcatcgtgcattgcagcgccggcatcggccgcacg
ggcaccatcattgtcatcgacatgctcatggagagcatctccaccaagggcctggactgt
gacatcgacatccagaagaccatccagatggtgcgggcccagcgctcgggcatggtgcag
acggaggctcagtacaagttcatctacgtggccatcgcccagttcatcgagaccaccaag
aagaagttggaggtcatgcagtcccagaagggccgggaatcggaatacgggaacatcacc
tacccgccagcgatgaagaacgcccacgccaaggcctcccgcacctcctctaaggaggac
gtgtatgagaatgtgcacagtaagaacaagaaggaggagaaggtgaagaaacagcggtca
gcagacaaggagaagaacaagggctccttgaagaggaagtga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (9)   
   KEGG PATHWAY (9)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   BGD-BTA (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (4)   
   UniProt (1)   
   RefSeq(pep) (3)   
DNA sequence (9)   
   RefSeq(nuc) (3)   
   GenBank (3)   
   EMBL (3)   
Protein domain (6)   
   Pfam (6)   
All databases (45)   

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