KEGG   Castor canadensis (American beaver): 109694006Help
Entry
109694006         CDS       T04791                                 

Gene name
Insr
Definition
(RefSeq) LOW QUALITY PROTEIN: insulin receptor
  KO
K04527  
insulin receptor [EC:2.7.10.1]
Organism
ccan  Castor canadensis (American beaver)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phospholipase D signaling pathway
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Longevity regulating pathway
Longevity regulating pathway - multiple species
Adherens junction
Insulin signaling pathway
Ovarian steroidogenesis
Regulation of lipolysis in adipocytes
Type II diabetes mellitus
Insulin resistance
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Module
PI3K-Akt signaling
Brite
KEGG Orthology (KO) [BR:ccan00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    109694006 (Insr)
   04015 Rap1 signaling pathway
    109694006 (Insr)
   04010 MAPK signaling pathway
    109694006 (Insr)
   04066 HIF-1 signaling pathway
    109694006 (Insr)
   04068 FoxO signaling pathway
    109694006 (Insr)
   04072 Phospholipase D signaling pathway
    109694006 (Insr)
   04022 cGMP - PKG signaling pathway
    109694006 (Insr)
   04151 PI3K-Akt signaling pathway
    109694006 (Insr)
   04152 AMPK signaling pathway
    109694006 (Insr)
   04150 mTOR signaling pathway
    109694006 (Insr)
 Cellular Processes
  Cellular community - eukaryotes
   04520 Adherens junction
    109694006 (Insr)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    109694006 (Insr)
   04923 Regulation of lipolysis in adipocyte
    109694006 (Insr)
   04913 Ovarian Steroidogenesis
    109694006 (Insr)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    109694006 (Insr)
  Aging
   04211 Longevity regulating pathway - mammal
    109694006 (Insr)
   04213 Longevity regulating pathway - multiple species
    109694006 (Insr)
 Human Diseases
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    109694006 (Insr)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    109694006 (Insr)
   04931 Insulin resistance
    109694006 (Insr)
Enzymes [BR:ccan01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     109694006 (Insr)
Protein kinases [BR:ccan01001]
 Tyrosine protein kinases
  InsR family [OT]
   109694006 (Insr)
Enzyme-linked receptors [BR:ccan01020]
 Receptor tyrosine kinases
  RTK class II (Insulin receptor family)
   109694006 (Insr)
Cytokine receptors [BR:ccan04050]
 Receptor tyrosine kinase
  RTK class II (Insulin receptor family)
   109694006 (Insr)
CD molecules [BR:ccan04090]
 Proteins
  109694006 (Insr)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
Position
Unknown
AA seq 1368 aa AA seqDB search
MGAGGRRGAAAAALLVAVASLLVGAAGHLYPGEVCPGMDIRNNLTRLHELENCSVIEGHL
QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLRDLFPNLTVIRGSRLFFNYAL
VVFEMVHLKELGLYNLMNITRGAVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDKE
ECGDVCPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECL
GNCSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHNKCKNSRRQG
CHQYVIHNNKCIPECPSGYTMNSSNLVCTPCQGPCPKVCHLLEGEKTIDSVTSAQELRGC
TVVNGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETL
EVGNYSFYALDNQNLRQLWDWSKHNLTIIQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE
RNDIALKTNGDQASCENELLKFSFIRTTFDKIMLKWEPYWPPDFRDLLGFMLFYKEAPYQ
NVTEFDGQDACGSNSWTVVDVDPPQRSNDPKSQKHPGWLMRGLKPWTQYAIFVKTLVTFS
DERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQILLKWKPPSDPNGNITHYLVYWE
RQAEDSELFELDYCLKGLKLPSRTWFPPFESKDSQKHNQSDYEDSTGDAGNCQASESXQE
MEXSLFKKTFEDYLHNVVFVPRPSRKRRSLGDVVNVTMAVPTIPVFPNVSSTVVPTTPEE
HRPFEKVVNKESLVISGLRHFTGYRIELQACNQDSPEERCSVAAYVSARTMPEAKADDII
GPVTHEIFENNVVHLMWQEPQEPNGLIVLYEVSYRRYGDEELHLCVSRKHFALERGCRLR
GLPPGNYSVRVRATSLAGNGSWTEPTYFYVTDYLDVPSNIAKIIIGPLIFVFLFSVVIGS
IYIFLRKRQPDGPMGPLYASSNPEYLSASDVFPCSVYVPDEWEVPREKITLLRELGQGSF
GMVYEGNAKDIVKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHVVRLLGVVS
KGQPTLVVMELMAQGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMAAEIADGMAYLNAKK
FVHRDLAARNCMVAHDFTVKIGDFGMTRDIYEMDYYRKGGKGLLPVRWMAPESLKDGVFT
ASSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDNCPERVTDLMHMCWQ
FNPKMRPTFLEIVNLLKDDLHPSFPEVSFFHSEENKAPESDELEMEFEDMENVPLDRSSH
CQREEAGGREGGSSLGIKRNYEEHIPYTHMNGGKKNGRILTLPRSNPS
NT seq 4107 nt NT seq  +upstreamnt  +downstreamnt
atgggcgccgggggtcggcggggggcggctgccgcggcgctgctggtggcggtggcctcg
ctcctggtgggcgccgcgggccacctgtaccctggagaggtgtgtcctggcatggacatt
cggaacaacctcaccaggctgcatgaactggagaactgctcggtgatcgagggacacctg
cagatcctgctgatgttcaagacgagacccgaggacttccgagacctcagcttccccaag
ctcatcatgatcactgactacctgctgctcttccgagtgtacgggctggagagcctgcgg
gacctgttccccaacctcacggttatccgcggctcccgcctcttcttcaactacgccctg
gtggtcttcgagatggttcacctgaaggagctggggctctacaacctgatgaacatcacc
cggggtgctgtccgcatcgagaagaacaatgagctgtgctacttggccaccatcgactgg
tctcgcatcctggactctgtggaggacaactatattgtcctgaacaaggacgacaaggag
gagtgtggagatgtctgtcctggcaccgccaagggcaagaccaactgccctgccactgtc
atcaatgggcagtttgtggagcgatgctggacccacagccattgccagaaagtttgcccc
accatctgcaagtcacacggctgcaccgctgaaggtctgtgctgccacagcgaatgccta
ggcaactgttctgagcctgatgaccccaccaagtgcgtggcctgccgaaacttctacctg
gacggcaggtgtgtggagacctgcccacccccctactaccacttccaggactggcgctgt
gtgaacttcagcttctgccaggacctgcacaacaagtgcaagaactccaggcgacagggc
tgccaccagtacgttattcacaacaacaagtgcatccctgagtgtccctctgggtacacg
atgaattccagcaatttggtctgcactccgtgtcaggggccctgccccaaggtctgtcac
ctcctagaaggcgagaagaccatcgactcggtgacgtctgcccaggaactccgaggctgc
actgtggtcaatggcagccttatcatcaacatccgaggaggcaacaacctggctgctgag
ctagaagctaacctcggcctcattgaagaaatttcaggttatctaaaaatccgccgatcc
tatgcccttgtgtctctttcctttttccggaagctacgtctgattcgaggagagactttg
gaagtcgggaactactctttctatgccttggacaaccagaacctgaggcagctgtgggac
tggagcaagcacaacctcaccatcattcaggggaagctcttcttccactacaaccccaag
ctctgcctgtctgaaatccacaagatggaagaggtctcgggaaccaagggtcgccaggag
aggaatgacattgccctcaagaccaatggggaccaggcttcctgtgaaaatgaattactt
aaattttctttcatccggacaacttttgacaagatcatgctgaaatgggagccttactgg
ccccctgacttccgagacctcttggggttcatgcttttctataaggaggccccttatcag
aacgtgacagagtttgacgggcaggacgcatgtggctccaacagctggacagtagtggac
gttgacccgccccagagatccaatgacccaaagtcacagaaacaccccggctggctgatg
cgggggctcaagccttggacccagtacgccatctttgtgaagaccttggttaccttttct
gatgaacggcggacctatggggccaagagtgacatcatctatgtgcagactgatgccacg
aatccctccgtccccctggatcccatctcggtttctaattcctcatcccagattcttttg
aagtggaagcctccctctgaccccaatggcaatatcacgcactacctggtttactgggag
aggcaggcggaagacagtgagctcttcgagctggattattgcctcaaagggttgaagctg
ccctcccggacatggttcccaccatttgagtccaaagattcccagaaacacaatcagagt
gactacgaggactccactggggatgctggtaactgccaggcgtccgagtcctgacaggag
atggaanggagtctcttcaagaagacctttgaggactacctgcacaacgtggtttttgtc
cccaggccctccaggaaacgcaggtctcttggtgacgtggtaaatgtgacaatggctgtg
cccacgatcccggttttccccaatgtctcctccactgtggtgcccacaacccccgaggag
cacaggcccttcgagaaagtagtgaacaaggagtccctggtcatctcaggcctgcgccac
ttcactggctaccgcatcgagctgcaggcctgcaaccaagactctcctgaagagaggtgc
agcgtggctgcctatgtcagtgccaggaccatgcctgaagccaaggcagatgatatcatt
ggccctgtgacccatgaaatctttgagaacaatgttgttcacttgatgtggcaagagcct
caggagcccaacggtctcattgtgctatatgaagtgagttatcggcgatacggcgatgag
gaactccatctctgtgtctccaggaagcattttgccctggagcggggctgcaggctgcgc
gggctgccaccggggaactacagtgtccgagtccgggccacctccctggctggcaatggc
tcctggacggaacccacctatttctatgtgacagattacttggacgtcccatcaaatatt
gcaaaaattatcatcgggccccttatcttcgtctttctcttcagtgtcgtgattggaagt
atttacatattcctgagaaagaggcaaccagatgggccaatgggaccactgtatgcttcc
tcaaaccccgagtacctcagtgccagtgatgtgtttccgtgctctgtgtacgtgccggat
gagtgggaggtccctcgagagaagatcaccctcctgcgggagctgggccaaggttccttt
ggcatggtgtatgagggcaacgccaaggacatcgtcaagggcgaggcagagacccgtgtg
gcggtgaaaacagtcaatgagtcagccagtctccgggagcggatcgagttcctcaatgag
gcatcggtcatgaaaggcttcacctgccatcatgtggttcgtctcctgggggtggtgtcg
aagggccagccaacgctggtggtgatggagctgatggctcaaggggacctgaagagctac
cttcgttccttgaggcctgaggctgagaataatccgggtcgccctcccccaaccctgcaa
gagatgattcaaatggcagcagagatagccgatggcatggcctacctgaacgctaagaag
tttgtgcaccgggacctggcagctcgaaactgcatggtcgcccatgattttaccgtcaaa
attggagactttggaatgaccagagacatctatgaaatggattactaccggaaagggggc
aagggcctgctgcctgtacggtggatggcacccgagtccctgaaggatggggtctttacc
gcatcttctgatatgtggtccttcggtgttgtcctttgggaaatcaccagcttagcagaa
cagccttaccaaggcctgtctaatgaacaggtgctgaaatttgtcatggatggagggtat
ctggatcagcccgacaattgtccagagagagtcaccgacttgatgcacatgtgttggcag
ttcaaccccaagatgcggccgaccttcctggagattgtcaacctgctcaaagatgaccta
catcccagctttccagaagtttccttcttccacagcgaggagaacaaggctcccgagagc
gatgagctggagatggagtttgaggacatggagaacgtcccattggatcgatcctcacac
tgtcagagggaggaggctgggggtcgggagggagggtcctctctgggcatcaagaggaac
tatgaagagcacatcccctacactcacatgaatgggggcaagaaaaacgggcggattctg
accctgcctcgctccaatccttcctaa

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