KEGG   PATHWAY: ccr02030Help
Entry
ccr02030                    Pathway                                

Name
Bacterial chemotaxis - Caulobacter crescentus CB15
Description
Chemotaxis is the process by which cells sense chemical gradients in their environment and then move towards more favorable conditions. In chemotaxis, events at the receptors control autophosphorylation of the CheA histidine kinase, and the phosphohistidine is the substrate for the response regulator CheY, which catalyzes the transfer of the phosphoryl group to a conserved aspartate. The resulting CheY-P can interact with the switch mechanism in the motor. This interaction causes a change in behavior, such as in direction or speed of rotation of flagella.
Class
Cellular Processes; Cell motility
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Pathway map
Bacterial chemotaxis
ccr02030

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BSID: 
GO: 
Organism
Caulobacter crescentus CB15 [GN:ccr]
Gene
methyl-accepting chemotaxis protein McpA; K03406 methyl-accepting chemotaxis protein [KO:K03406]
methyl-accepting chemotaxis protein McpK; K03406 methyl-accepting chemotaxis protein [KO:K03406]
methyl-accepting chemotaxis protein McpQ; K03406 methyl-accepting chemotaxis protein [KO:K03406]
methyl-accepting chemotaxis protein McpC; K03406 methyl-accepting chemotaxis protein [KO:K03406]
methyl-accepting chemotaxis protein McpB; K03406 methyl-accepting chemotaxis protein [KO:K03406]
methyl-accepting chemotaxis protein McpN; K03406 methyl-accepting chemotaxis protein [KO:K03406]
methyl-accepting chemotaxis protein McpP; K03406 methyl-accepting chemotaxis protein [KO:K03406]
methyl-accepting chemotaxis protein McpD; K03406 methyl-accepting chemotaxis protein [KO:K03406]
methyl-accepting chemotaxis protein McpM; K03406 methyl-accepting chemotaxis protein [KO:K03406]
methyl-accepting chemotaxis protein McpO; K03406 methyl-accepting chemotaxis protein [KO:K03406]
methyl-accepting chemotaxis protein McpI; K03406 methyl-accepting chemotaxis protein [KO:K03406]
methyl-accepting chemotaxis protein McpH; K03406 methyl-accepting chemotaxis protein [KO:K03406]
methyl-accepting chemotaxis protein McpE; K03406 methyl-accepting chemotaxis protein [KO:K03406]
methyl-accepting chemotaxis protein McpJ; K03406 methyl-accepting chemotaxis protein [KO:K03406]
chemotaxis protein CheA; K03407 two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] [KO:K03407] [EC:2.7.13.3]
chemotaxis protein CheA; K03407 two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] [KO:K03407] [EC:2.7.13.3]
chemotaxis protein CheW; K03408 purine-binding chemotaxis protein CheW [KO:K03408]
chemotaxis protein CheW; K03408 purine-binding chemotaxis protein CheW [KO:K03408]
chemotaxis protein CheW; K03408 purine-binding chemotaxis protein CheW [KO:K03408]
chemotaxis protein CheW; K03408 purine-binding chemotaxis protein CheW [KO:K03408]
chemotaxis protein CheY; K03413 two-component system, chemotaxis family, response regulator CheY [KO:K03413]
chemotaxis protein CheY; K03413 two-component system, chemotaxis family, response regulator CheY [KO:K03413]
chemotaxis protein CheY; K03413 two-component system, chemotaxis family, response regulator CheY [KO:K03413]
chemotaxis protein CheY; K03413 two-component system, chemotaxis family, response regulator CheY [KO:K03413]
chemotaxis protein CheY; K03413 two-component system, chemotaxis family, response regulator CheY [KO:K03413]
chemotaxis protein CheY; K03413 two-component system, chemotaxis family, response regulator CheY [KO:K03413]
CheX protein; K03409 chemotaxis protein CheX [KO:K03409]
chemotaxis-specific methylesterase; K03412 two-component system, chemotaxis family, response regulator CheB [EC:3.1.1.61] [KO:K03412] [EC:3.1.1.61]
chemotaxis-specific methylesterase; K03412 two-component system, chemotaxis family, response regulator CheB [EC:3.1.1.61] [KO:K03412] [EC:3.1.1.61]
chemotaxis protein CheD; K03411 chemotaxis protein CheD [EC:3.5.1.44] [KO:K03411] [EC:3.5.1.44]
chemotaxis protein CheR; K00575 chemotaxis protein methyltransferase CheR [EC:2.1.1.80] [KO:K00575] [EC:2.1.1.80]
chemotaxis protein CheR; K00575 chemotaxis protein methyltransferase CheR [EC:2.1.1.80] [KO:K00575] [EC:2.1.1.80]
chemotaxis protein CheR; K00575 chemotaxis protein methyltransferase CheR [EC:2.1.1.80] [KO:K00575] [EC:2.1.1.80]
fliG; flagellar motor switch protein G [KO:K02410]
flagellar motor switch protein; K02417 flagellar motor switch protein FliN/FliY [KO:K02417]
hypothetical protein; K02417 flagellar motor switch protein FliN/FliY [KO:K02417]
flagellar motor protein MotA; K02556 chemotaxis protein MotA [KO:K02556]
chemotaxis protein MotB; K02557 chemotaxis protein MotB [KO:K02557]
Compound
C00049  
L-Aspartate
C00107  
Dipeptide
C00121  
D-Ribose
C00124  
D-Galactose
C00208  
Maltose
C00716  
DL-Serine
Reference
  Authors
Kristich CJ, Ordal GW.
  Title
Bacillus subtilis CheD is a chemoreceptor modification enzyme required for chemotaxis.
  Journal
J Biol Chem 277:25356-62 (2002)
Reference
  Authors
Kirby JR, Kristich CJ, Saulmon MM, Zimmer MA, Garrity LF, Zhulin IB, Ordal GW.
  Title
CheC is related to the family of flagellar switch proteins and acts independently from CheD to control chemotaxis in Bacillus subtilis.
  Journal
Mol Microbiol 42:573-85 (2001)
Reference
  Authors
Szurmant H, Bunn MW, Cannistraro VJ, Ordal GW.
  Title
Bacillus subtilis hydrolyzes CheY-P at the location of its action, the flagellar switch.
  Journal
J Biol Chem 278:48611-6 (2003)
Reference
  Authors
Szurmant H, Muff TJ, Ordal GW.
  Title
Bacillus subtilis CheC and FliY are members of a novel class of CheY-P-hydrolyzing proteins in the chemotactic signal transduction cascade.
  Journal
J Biol Chem 279:21787-92 (2004)
Reference
  Authors
Yoshihara S, Geng X, Okamoto S, Yura K, Murata T, Go M, Ohmori M, Ikeuchi M.
  Title
Mutational analysis of genes involved in pilus structure, motility and transformation competency in the unicellular motile cyanobacterium Synechocystis sp. PCC 6803.
  Journal
Plant Cell Physiol 42:63-73 (2001)
Reference
PMID:8104179
  Authors
Darzins A.
  Title
The pilG gene product, required for Pseudomonas aeruginosa pilus production and twitching motility, is homologous to the enteric, single-domain response regulator CheY.
  Journal
J Bacteriol 175:5934-44 (1993)
Reference
  Authors
Szurmant H, Ordal GW
  Title
Diversity in chemotaxis mechanisms among the bacteria and archaea.
  Journal
Microbiol Mol Biol Rev 68:301-19 (2004)
Reference
  Authors
Rao CV, Glekas GD, Ordal GW
  Title
The three adaptation systems of Bacillus subtilis chemotaxis.
  Journal
Trends Microbiol 16:480-7 (2008)
Reference
  Authors
Muff TJ, Ordal GW
  Title
The diverse CheC-type phosphatases: chemotaxis and beyond.
  Journal
Mol Microbiol 70:1054-61 (2008)
Reference
  Authors
Miller LD, Russell MH, Alexandre G
  Title
Diversity in bacterial chemotactic responses and niche adaptation.
  Journal
Adv Appl Microbiol 66:53-75 (2009)
KO pathway
 

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