KEGG   Caenorhabditis elegans (nematode): CELE_C54D1.3Help
Entry
CELE_C54D1.3      CDS       T00019                                 

Gene name
ist-1
Definition
(RefSeq) Insulin receptor SubsTrate homolog
  KO
K16172  
insulin receptor substrate 1
Organism
cel  Caenorhabditis elegans (nematode)
Pathway
FoxO signaling pathway
Autophagy - animal
mTOR signaling pathway
Longevity regulating pathway - worm
Longevity regulating pathway - multiple species
Module
PI3K-Akt signaling
Brite
KEGG Orthology (KO) [BR:cel00001]
 Environmental Information Processing
  Signal transduction
   04068 FoxO signaling pathway
    CELE_C54D1.3 (ist-1)
   04150 mTOR signaling pathway
    CELE_C54D1.3 (ist-1)
 Cellular Processes
  Transport and catabolism
   04140 Autophagy - animal
    CELE_C54D1.3 (ist-1)
 Organismal Systems
  Aging
   04212 Longevity regulating pathway - worm
    CELE_C54D1.3 (ist-1)
   04213 Longevity regulating pathway - multiple species
    CELE_C54D1.3 (ist-1)
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
WormBase: 
UniProt: 
Position
X:join(7126651..7126865,7132152..7132336,7132891..7133123,7133536..7133673,7133732..7133906,7133949..7134072,7134127..7134244,7134302..7134489,7134541..7134552,7135779..7136000,7136051..7136189,7136240..7136440,7136880..7137124,7137174..7137335,7137385..7137866,7138777..7138921,7138973..7139270)
Genome map
AA seq 1093 aa AA seqDB search
MSEEEESTDNSGKPPIEHPHDREVKSEKQSSNVLPGILRRAESTDDAHQVRRSSMRPYES
FDGLKNDGILKRKRSFFVKTVSFSATVSELMLPAEPTSGEPKNDGEYVETMFDATEEKKQ
ETIAPKQEETVKKLSMAAREERIRESRQQGQLKEKRLKNPDSKGDTSHDKPTRETWKPLA
VEDLPKDEDPDEFGIPEVYKCGNCLVGFAPVKKKKLMFVTLTERCLELHESEKSYRAGKA
AKHMVDLSMSFNVHSEHYDAKLKKCLCLMGPDETICMRPEGGILTIEGWRRAIVKLIHES
RRRKMDRVPRPEDIFDAAYDVRVCLFPKNLEKYVESLKTDGFTNICTVAKELLGKKRLCL
YPNTLAIVDLCIEPTAYGLPPAGFPPFRASSMFILERNTVAYYGFRENYFYVRIGKGSPY
RGFELLFQVDTNEVCKEIYSRLRALADRDLENRKQESIRRPERPRVSTLQSVKPGKEETG
LREALLESYGHLRKKNSTQSERGEIVVPEQERKMSDNRPRLRTQDIKTVTKPELKSEEPI
RPRLPPLKFNANKPSGEFLLSLQREKELMEEARKNGYDGRTHNPDGTPREIKKDFLDTVC
PQAAAPEVVIKEKIINNDTYTLMGPADWGKLEDIVKDDYSDSGDSCYSSRRGTGSQPTRP
AASHLACQMQNRTQSFGAKQQTFQNRLPPTVNLPDSERKISAANQGTSNQLDLPQEDPRK
RAFSLGSKNFFNLIGLNDFRRLVSKRHRTSSPNHTSTSGISLNSSNASPSASSNFLASSE
YLEHARTDSFGSARSSPKSLHTQRTSSPKRRSDEDLISIDFSRLGKNSASDTKRFPFGGG
GPGGSFDYDREKREKEDNNRRDREKAAMDLKRKEEWEARELAEKKRELERKIQAKKDRKL
EKGRGKDREKDKDHDHDKEFRPKADSGIADCTPSSSFSGKKDHKNDGSSDSAYMDKEGLK
YLADIKKRKKEQGAIDTTNSSSSSLSTIVSIEDNKVTRRITETVETKVVTADLAKALGAI
DPNRRSSACIEINRKPSICTAIMEEREGEASETDSRGEPSDRKTTAAPVTRKPASTGSSM
SPFRRLKFLSFRK
NT seq 3282 nt NT seq  +upstreamnt  +downstreamnt
atgtctgaagaagaagaatctacagataattctgggaaaccccctatagaacatccgcat
gatagagaggttaaatcagaaaaacaatcatcaaatgtgcttcctggaatattgcgacga
gctgaatccacggatgatgctcatcaagtcagacgatcatcaatgcgaccatatgaatct
ttcgatggtttaaaaaatgatggaatactgaaaagaaagagaagcttttttgtgaaaaca
gtgagcttcagcgcaacggtgtctgagctgatgttgcccgccgagcctacatctggtgaa
ccgaaaaatgacggagagtacgttgagacaatgtttgacgccacggaagagaagaaacaa
gaaacgattgcgccaaaacaggaagaaactgtaaagaaattatcaatggcagcaagagag
gagagaatacgcgaaagtagacaacaagggcaactgaaagaaaaaaggctgaaaaatcca
gattcaaaaggtgatacaagtcacgataagccgaccagagaaacatggaagccgttagcc
gttgaagacttaccaaaggatgaagatccggatgaatttggaattccagaagtctacaaa
tgtggaaattgtttagtagggtttgctccagtgaaaaagaaaaagctaatgtttgtgaca
ctcacggaacgatgtttagaacttcacgagtcggagaaatcctatcgtgcgggaaaagca
gcaaagcatatggtagatctctcaatgtcttttaatgtgcacagtgagcattacgatgca
aaactaaagaaatgcctatgcttgatgggtccagacgaaacaatatgcatgagaccggaa
ggaggaattctaaccattgaaggttggcgacgagcaattgtaaaactaattcatgaatca
agaagaagaaaaatggaccgcgttccgagacctgaagatatttttgatgctgcatatgat
gtacgtgtttgtctatttccaaaaaacttggaaaaatacgtggaaagcttgaaaacagac
gggttcacaaacatatgtactgttgccaaagagcttttaggaaagaaaagattatgcctt
tatccaaatacacttgccattgttgatctctgcattgaaccaactgcctatggtctccca
cctgccgggtttcccccattccgtgcatcaagcatgttcattttggagcgaaatacggtt
gcttactacggttttcgtgaaaactatttctatgtacgaattggaaagggaagcccctat
cgagggtttgagttattgttccaagtggacactaacgaagtttgtaaggaaatttactca
cgtcttagagcactcgctgatcgtgatcttgaaaaccggaaacaagaatctatacggaga
ccagaaagaccccgtgtttctactcttcaaagtgtgaaaccgggcaaagaagaaaccgga
ctacgtgaagcacttcttgaatcatatggccatttaagaaaaaagaattcaacacaatca
gagcgaggagagatagttgttccggagcaagaacggaaaatgtcagacaacaggcctcgg
ctcagaactcaggatataaaaactgttacaaagcctgaactgaaatcagaagaacctata
cgcccgagacttccaccgctaaaattcaatgctaacaaaccgtctggagaatttttatta
tcgctccaacgggagaaagagttaatggaagaggcaagaaaaaatggttatgatggaaga
acacacaatcctgatgggactcctcgagaaatcaaaaaagatttcctcgacactgtttgt
ccacaagctgcagcgccagaagttgtgatcaaagagaaaatcataaacaacgatacttat
acgctgatgggtccagccgactggggaaaactggaagatattgtcaaagatgattactcg
gacagtggggacagttgttattcatcaagaagaggaaccggtagtcaaccgacccgaccg
gccgcttctcacctcgcatgtcaaatgcaaaaccgaacacagtcatttggagctaaacaa
caaacatttcaaaaccgacttccgcctactgtaaatctgcctgattctgaaagaaaaatt
tcggctgccaaccaaggaacgtcaaaccaactcgaccttccacaagaagatccaagaaaa
agagcattctcattgggaagtaaaaactttttcaacctgataggattgaatgactttcgt
cgccttgtaagcaagcgtcatcgaacatcatctccaaaccacacctctacttctggtatc
tcgttaaactcatctaacgcatccccgtcagcaagtagtaattttttggcttcttctgaa
tatttagaacatgcaagaactgatagttttgggtccgcaagaagtagtccaaaaagtcta
cacacccagcgaaccagttcaccgaaaagaagatcggacgaggatctgatctcaattgac
ttttcaagattaggtaaaaattctgcatcagatacaaaacgatttccttttggtggagga
ggaccaggagggtcctttgattatgatagagaaaaacgggaaaaggaagataataataga
cgagaccgagaaaaagcagcaatggatttgaaaagaaaagaagaatgggaagcgagagaa
ttagcggaaaagaagagggagttggaacggaaaattcaagcaaagaaagatagaaaattg
gagaagggaagagggaaagatagagaaaaggataaagaccacgatcatgataaggagttt
cgtccaaaagcggacagtggaattgctgattgtacgcccagttcaagtttttctgggaag
aaagatcacaaaaatgatggttcttctgattctgcatacatggacaaagaagggttgaag
tacttggcagatatcaaaaaacggaaaaaagagcaaggtgccatagacacaacaaattcc
tcctcctcctcgttaagcacaatagtttcgattgaagataacaaagtgaccagaagaatc
acggaaaccgttgaaacaaaagttgtgactgcggatctagcgaaagcacttggtgcaatt
gacccgaatagaagatcttcagcatgcattgagataaatcgaaaaccatcgatttgtaca
gcaataatggaagaaagagaaggagaagcatctgagaccgattctaggggagaaccatcc
gacaggaagacgaccgcggcccctgtaactcggaaacctgcatcgactggcagcagcatg
agcccgttcagaagacttaaatttctcagcttcagaaaataa

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