KEGG   Canis familiaris (dog): 100688870Help
Entry
100688870         CDS       T01007                                 

Gene name
CACNA2D2
Definition
calcium channel, voltage-dependent, alpha 2/delta subunit 2
Orthology
K04859  
voltage-dependent calcium channel alpha-2/delta-2
Organism
cfa  Canis familiaris (dog)
Pathway
MAPK signaling pathway
Cardiac muscle contraction
Adrenergic signaling in cardiomyocytes
Oxytocin signaling pathway
Hypertrophic cardiomyopathy (HCM)
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:cfa00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    100688870 (CACNA2D2)
 Organismal Systems
  Endocrine system
   04921 Oxytocin signaling pathway
    100688870 (CACNA2D2)
  Circulatory system
   04260 Cardiac muscle contraction
    100688870 (CACNA2D2)
   04261 Adrenergic signaling in cardiomyocytes
    100688870 (CACNA2D2)
 Human Diseases
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    100688870 (CACNA2D2)
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    100688870 (CACNA2D2)
   05414 Dilated cardiomyopathy (DCM)
    100688870 (CACNA2D2)
Ion channels [BR:cfa04040]
 Voltage-gated cation channels
  Ca2+ channel, CACN alpha-2 delta
   100688870 (CACNA2D2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
20
AA seq 1109 aa AA seqDB search
MLPLLAAPGASAYSFPQQHTMQHWARRLEQEIDGVMRIFGGVQQLREIYKDNRNLFEVQE
NEPQKLVEKVAGDIESLLDRKVRALKRLADAAENFQKAHRWQDNIKEEDILYYDAKADAE
LDDPESEDVERGSKVSTLRLDFVEDSNFKNKVNYSYTAVQIPTDIYKGSTVILNELNWTE
ALENVFIENRRQDPTLLWQVFGSATGVTRYYPATPWRAPKKIDLYDVRRRPWYIQGASSP
KDMVIIVDVSGSVSGLTLKLMKTSVCEMLDTLSDDDYVNVASFNEKAQPVSCFTHLVQAN
VRNKKVSRKPCRAXXXXXXXXXXXXXMVARAPRLQAGFEYAFDQLQNSNITRANCNKMIM
MFTDGGEDRVQDVFEKYNWPNRTVRVFTFSVGQHNYDVTPLQWMACANKGYYFEIPSIGA
IRINTQEYLDVLGRPMVLAGKEAKQVQWTNVYEDALGLGLVVTGTLPVFNLTQDGPGEKK
NQLILGVMGIDVALNDIKRLTPNYTLGANGYVFAIDLNGYVLLHPNLKPQTTNFREPVTL
DFLDAELEDENKEEIRRSMIDGNKGHKQIRTLVKSLDERYVDEVVRNYTWVPIRSTNYRD
LGLVLPPYSTFYLQANLSDQILQVKYFEFLLPSSFESEGHVFIAPREYCKDLNASDNNTE
FLKNFIELMEKVTPDSKQCNNFLLHNLILDTGITQQLVERVWRDQDLNTYSLLAVFAATD
GGITRVFPNKAAEDWMENPEPFNASFYRRSLDNHGYIFKPPHQDALLRPLELENDTVGIL
VSTAVELSLGGRTLRPAVVGVKLDLEAWAEKFKVLASNRTHQDQPQKCGPSSHCEMDCEV
NNEDLLCVLIDDGGFLVLSNQNHQWDQVGRFFSEVDANLMLALYNNSFYTRKESYDYQAA
CAPQPPGNLGAAPRGVFVPTIADFLNLAWWTSAAAWSLFQQLLYGLIYHSWFQADSAEAE
GSPEARESSCVMKQTQYYFGSVNASYNAIIDCGNCSRLFHAQRLTNTNLLFVVAEKPLCS
QCEAGRLLQKETHCPADGSEQCELVQRPRYRRGPHICFDYYATEDTSDCGRGASFPPSLG
VLVSLQLLLLLGLPPRPQPQVPAHASRRL
NT seq 3330 nt NT seq  +upstreamnt  +downstreamnt
atgctgccactgctcgccgccccgggcgcgtctgcatacagcttcccccagcagcacacg
atgcagcactgggcccgacgcctggagcaagagattgatggcgtgatgcggatctttggg
ggtgtccagcagctccgtgagatctacaaggacaaccggaatctgtttgaggtgcaggag
aacgagcctcagaagttggtggaaaaggtggcaggagacattgagagcctgctggacagg
aaggtgcgggccctgaagagactggccgatgctgccgagaacttccagaaagcccaccgc
tggcaggacaacatcaaggaggaagatatcctgtactatgacgccaaggctgacgctgag
ctggacgaccctgagagtgaggatgtggagagggggtccaaggtcagcaccctaaggctg
gacttcgttgaggactcaaacttcaagaacaaagtcaactattcgtacacggccgtgcag
atccccacggacatctacaaaggctctactgtcatccttaacgaactcaactggacagaa
gccctggagaatgtgttcattgagaatcgccggcaggaccccacgctgctgtggcaggtc
ttcggaagtgccacgggagtcactcgctactacccagccaccccatggcgagcccccaag
aaaatcgacctgtatgatgtccgaaggagaccctggtatatccagggggcctcatcaccc
aaggacatggtcatcatcgtggacgtgagtggcagtgtgagcggcctgaccctgaagctg
atgaagacgtccgtctgtgagatgctggacacgctctcagatgatgactatgtgaacgtg
gcctcgttcaatgaaaaggcacagcctgtgtcatgcttcacacatctggtgcaggccaat
gtgcgtaacaagaaggtttcaaggaagccgtgcagggcatgnnnnnnnnnnnnnnnnnnn
nnnnnnnnnnnnnnnnnnatggtggccagggcaccaaggctacaggccggttttgagtat
gccttcgaccagctgcagaactccaacatcactcgtgccaactgcaataagatgatcatg
atgttcacggacggtggtgaggaccgtgtgcaggatgtctttgagaagtacaattggccc
aaccggacggtgcgcgtgttcactttttccgtggggcagcacaactacgacgtcacaccc
ctgcagtggatggcctgcgccaacaaaggttactattttgagatcccttccattggagcc
atccgcattaacacgcaggaatatctggacgtactgggcaggcccatggtgctagctggc
aaggaggccaagcaggtgcaatggaccaacgtgtatgaggatgctctggggctgggattg
gtggtgacagggaccctccctgttttcaacctgacacaggatggccctggggagaaaaag
aaccagctgatcctgggtgtgatgggcatcgatgtggctctgaatgacatcaagaggctg
accccaaactacacacttggagccaacgggtacgtgtttgccattgacctgaatggctac
gtgttgctgcaccccaacctcaagccccagaccaccaacttccgagagcctgtgactctg
gacttcctggacgccgagctggaggatgagaacaaggaggagatccgtcggagcatgatt
gatggcaacaagggccacaagcagatcagaacactggtcaagtccctggacgagaggtac
gtagacgaggtggtgcggaactacacctgggtgcctataaggagcaccaactacagagac
ctcgggcttgtgctcccaccctacagcaccttctacctccaagccaacctcagcgaccag
atcctgcaggtcaagtattttgagttcctgctccccagcagctttgagtctgaaggacat
gttttcattgctcccagagagtattgcaaggacctgaatgcctcagacaacaacaccgag
ttcctgaaaaacttcattgagctcatggagaaagtgactccagactccaagcagtgcaac
aactttcttctgcacaacctaatcttggacacgggcatcacacagcagctggtagagcga
gtgtggcgggaccaagatctcaacacgtacagccttctggccgtgtttgctgccaccgac
ggcggcatcactcgcgttttccccaacaaagcagctgaggactggatggagaacccggag
cccttcaatgccagcttctatcgccgtagcctggacaaccacggctatatcttcaaaccc
ccacatcaggatgccctgttaaggccactggagctggagaatgacacggtgggcatcctc
gtcagcacagctgtggagctaagcctgggcgggcgcacactgaggccagcagtggtaggt
gttaagctggacctagaggcctgggctgagaagttcaaggtgctagccagcaaccgtacc
caccaggaccagcctcagaagtgtggccctagcagccactgtgagatggactgcgaggtt
aacaatgaggacctgctctgtgtcctcattgatgatgggggattcctggtgctgtcaaac
cagaatcatcagtgggaccaggtgggcaggttcttcagtgaggtggacgccaacctgatg
ctggcactctacaataactccttctacacccgcaaagagtcctacgattatcaggcagcc
tgcgccccccagccccctggcaacctgggtgctgcaccgcggggcgtctttgtgcccacc
attgcagacttccttaacctggcctggtggacctccgctgcagcctggtccttgttccag
cagctcctctatggcctcatctatcacagctggttccaggcagactccgcggaggccgag
gggagccccgaggcgcgcgagagcagctgcgtcatgaaacagactcagtactacttcggg
tcggtgaacgcctcctacaacgccatcatcgactgcggaaactgctccaggctgttccac
gcgcagagactgaccaacaccaaccttctcttcgtggtggccgagaagccgctgtgcagc
cagtgtgaggctggccggctgctgcagaaggagacacactgcccagcggacggctcggag
cagtgtgaactggtgcagagaccgcgataccggagaggcccgcacatctgctttgactac
tacgcgaccgaagatacctcagactgcggccgcggagcttccttcccgccgtcgctgggc
gtcctggtctccctgcagctgctgctcctcctgggcctgcctccccggcctcagccccaa
gtccccgcccacgcctcgcgccgcctctga

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