KEGG   Canis familiaris (dog): 100856190Help
Entry
100856190         CDS       T01007                                 

Gene name
PLCB2
Definition
phospholipase C, beta 2
Orthology
K05858  
phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
cfa  Canis familiaris (dog)
Pathway
Inositol phosphate metabolism
Metabolic pathways
Rap1 signaling pathway
Calcium signaling pathway
Chemokine signaling pathway
Phosphatidylinositol signaling system
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Wnt signaling pathway
Gap junction
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
Dopaminergic synapse
Long-term depression
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Endocrine and other factor-regulated calcium reabsorption
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Alzheimer's disease
Huntington's disease
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Amoebiasis
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Class
Metabolism; Carbohydrate metabolism; Inositol phosphate metabolism [PATH:cfa00562]
Environmental Information Processing; Signal transduction; Rap1 signaling pathway [PATH:cfa04015]
Environmental Information Processing; Signal transduction; Wnt signaling pathway [PATH:cfa04310]
Environmental Information Processing; Signal transduction; Calcium signaling pathway [PATH:cfa04020]
Environmental Information Processing; Signal transduction; Phosphatidylinositol signaling system [PATH:cfa04070]
Cellular Processes; Cell communication; Gap junction [PATH:cfa04540]
Organismal Systems; Immune system; Chemokine signaling pathway [PATH:cfa04062]
Organismal Systems; Endocrine system; Insulin secretion [PATH:cfa04911]
Organismal Systems; Endocrine system; GnRH signaling pathway [PATH:cfa04912]
Organismal Systems; Endocrine system; Estrogen signaling pathway [PATH:cfa04915]
Organismal Systems; Endocrine system; Oxytocin signaling pathway [PATH:cfa04921]
Organismal Systems; Endocrine system; Thyroid hormone synthesis [PATH:cfa04918]
Organismal Systems; Endocrine system; Thyroid hormone signaling pathway [PATH:cfa04919]
Organismal Systems; Endocrine system; Melanogenesis [PATH:cfa04916]
Organismal Systems; Circulatory system; Adrenergic signaling in cardiomyocytes [PATH:cfa04261]
Organismal Systems; Circulatory system; Vascular smooth muscle contraction [PATH:cfa04270]
Organismal Systems; Digestive system; Salivary secretion [PATH:cfa04970]
Organismal Systems; Digestive system; Gastric acid secretion [PATH:cfa04971]
Organismal Systems; Digestive system; Pancreatic secretion [PATH:cfa04972]
Organismal Systems; Excretory system; Endocrine and other factor-regulated calcium reabsorption [PATH:cfa04961]
Organismal Systems; Nervous system; Glutamatergic synapse [PATH:cfa04724]
Organismal Systems; Nervous system; Cholinergic synapse [PATH:cfa04725]
Organismal Systems; Nervous system; Dopaminergic synapse [PATH:cfa04728]
Organismal Systems; Nervous system; Serotonergic synapse [PATH:cfa04726]
Organismal Systems; Nervous system; Long-term potentiation [PATH:cfa04720]
Organismal Systems; Nervous system; Long-term depression [PATH:cfa04730]
Organismal Systems; Nervous system; Retrograde endocannabinoid signaling [PATH:cfa04723]
Organismal Systems; Sensory system; Inflammatory mediator regulation of TRP channels [PATH:cfa04750]
Organismal Systems; Environmental adaptation; Circadian entrainment [PATH:cfa04713]
Human Diseases; Neurodegenerative diseases; Alzheimer's disease [PATH:cfa05010]
Human Diseases; Neurodegenerative diseases; Huntington's disease [PATH:cfa05016]
Human Diseases; Infectious diseases; Amoebiasis [PATH:cfa05146]
Human Diseases; Infectious diseases; Chagas disease (American trypanosomiasis) [PATH:cfa05142]
Human Diseases; Infectious diseases; African trypanosomiasis [PATH:cfa05143]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
UniProt: 
Position
30
AA seq 1188 aa AA seqDB search
MSLLSPVLLPPKVEAYLSQGERFIKWDDETTIASPVILRVDPKGYYLYWTYQSKETEFLD
ITSIRDTRFGKFAKIPKSQKLREVFNMDFPDNNFLLKTLTVVSGPDMVDLTFHNFVSYKE
NVGKNWAEDVLALAKHPLTANASRSTFLDKILVKLKMQLNPEGKIPVKNFFQMFPADRKR
VEAALSACHLPKGKNDAINPEDFPESVYKSFLMNLCPRPEIDEIFTSYHAKAKPYMTKEH
LTKFINQKQRDPRLNSLLFPPARPDQVRGLIDKYEPSGINVQRGQLSPEGMVWFLCGPEN
SVLSQDKLLLHHDMTQPLNHYFINSSHNTYLTAGQFSGLSSAEMYRQVLLAGCRCVELDC
WKGKPPDEEPIITHGFTMTTDIYFKEAIEAIAESAFKTSPYPVILSFENHVDSPRQQAKM
AEYCRMMFGDMLLTEPLEKFPLKPGIPLPSPEDLRGKILIKNKKNQFSGPAAPSKESGGD
AEGNCPPNASVGEGTVWPGEEGEELEEEEVEEEEEEESGNLDEEEIKKMQSDEGTAGLEV
TAYEEMSSLVNYIQPTKFISFELSAQKNRSYVISSFTELKAYDLLSKASVKFVDYNKRQM
SRIYPKGTRMDSSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMALFEFNGQSGYLLKHEF
MRRPDKQFNPFSVDRIDVVVATTLSITVISGQFLSERSVRTYVEVELFGLPGDPKRRYRT
RLSPSANSINPVWKEEPFVFEKILMPELASLRVAVMEEGNKFLGHRIIPINALNSGYHHL
CLHSESNMPLTMPALFVFLEMKDYVPDTWADLTVALANPIKFFSAHDKKSVKLKEAMGAL
PEKPFPTGSPVAGQVNGPLAPVSNGSAAARARAGEEAAKEAAEPQTASPEELQELKGVVK
LQRRHEKELRDLERRGARRREELLQRGAAQLAGLGPPGAGGCGGRRLGPGKGSRKKRTSP
CDEAAGAAPQEDREGPEGADARARELKDRLELELLQQGEEQYECILKRKEQHVAEQIAKM
MELAREKQAAELKTLKETLETDTKEMKKKLEAKRLERIQAMVKVTSDKMAQERLKREINN
SHIQEVVQVIKQMTESLEKHQEKLEEKQAACLEQIREMEKQFQQEALAEYEARMKGLEAE
VKESVRACLRGCFPSEAKDMPERPCEAFRELCEQDPLAAKAGAQESRL
NT seq 3567 nt NT seq  +upstreamnt  +downstreamnt
atgtctctgctcagccctgtcctgctgccccccaaggtggaggcttatctgagccaaggg
gagcgcttcatcaaatgggacgatgaaaccacgatagcttctccggttatccttcgtgtg
gatcccaagggctactacttatattggacatatcagagtaaggagacggagtttctagat
atcaccagcatcagggatacccgctttgggaagtttgccaagatacccaagagccagaag
ctccgagaggtcttcaacatggactttcctgacaacaacttcctgctaaagacactcacc
gtggtatctggccctgacatggtggacctcaccttccacaactttgtctcctacaaggag
aatgtgggcaagaactgggctgaagacgtgctggctctggccaagcacccactgacggcc
aatgcttcccgcagcaccttcttggacaaaatcctggtgaaactcaagatgcagctcaac
cccgaagggaagattcctgtgaaaaattttttccagatgtttcctgctgaccgcaagcgg
gtagaagctgccctcagtgcctgccacctcccaaaaggcaagaatgatgccatcaatcct
gaggacttcccagaatctgtctacaagagtttcctcatgaacctctgtcctcggccagaa
atagacgagatcttcacttcttaccatgccaaggccaaaccctacatgaccaaggagcat
ctgaccaaattcatcaaccagaaacagagggacccccgtctcaactccttgctgtttcca
cctgcgcggcctgaccaggtgcggggcctcatcgacaagtatgaacccagtggcatcaac
gtgcagaggggccagctatcacctgagggcatggtgtggtttctgtgtggcccagagaac
agcgtcctgtcccaggacaagctgctactccaccacgacatgacgcagccactcaaccat
tacttcatcaactcctcacacaacacctacctgacagccggccagttctctggcctctcc
tcggcagagatgtaccgccaggtgctgctggctggctgccgctgtgtggagctggactgc
tggaagggcaagccccctgacgaggagcccatcatcacccatggcttcaccatgaccaca
gacatctatttcaaggaagccattgaagccattgcagaaagtgcctttaagacctccccc
tatcctgtcatcctgtcatttgaaaaccatgtggactcaccccgccaacaggccaagatg
gctgagtactgccggatgatgtttggggatatgctgctcacagagcccttggaaaagttc
ccactgaaaccaggcatccctctgcctagccctgaggatctccgaggcaagatcctcatc
aagaacaaaaagaaccagttttctggcccagcagcccccagcaaggaatccggtggggac
gctgagggcaactgcccacctaatgcctctgtgggtgagggcacagtgtggcctggtgag
gaaggggaagagctggaggaggaagaggtggaggaagaggaggaggaggagtcgggaaac
ctggatgaggaagagatcaagaagatgcagtcggatgagggcacggcgggcctggaggtg
acagcctacgaggagatgtccagcctcgtgaattacatccaacccaccaaattcatctcc
ttcgagctctctgcccagaagaaccgaagttatgtcatctcgtccttcacagagctcaag
gcttatgacctgctctccaaggcctcagtgaagtttgtggactacaacaagcgccagatg
agccgcatttaccctaagggcacccgcatggactcctccaactacatgccccagatgttc
tggaatgctggttgccagatggttgccctcaacttccagactatggacctgcccatgcag
cagaacatggcgctgttcgagttcaatgggcagagtggttacctcctcaagcatgagttc
atgcgccgcccagacaagcagttcaaccccttctcggtggatcgcattgacgtggtggta
gccaccaccctgtccattacggtgatctctgggcagttcctgtctgaacgcagtgtgcgc
acctatgtggaagtagaactctttggccttcctggggaccccaagaggcgctatcgcacc
aggctgtcacccagtgccaactccatcaatcctgtctggaaggaagagccttttgtcttt
gagaagatcttgatgcctgagctggcctctctcagggtggctgtaatggaggaaggcaac
aaatttcttggacaccgcatcatccccattaatgccctgaattctggctaccaccatctg
tgcctgcacagcgagagcaacatgccccttaccatgcctgcgctttttgtcttcttggag
atgaaggactatgtacctgacacctgggcagatctcaccgtggctcttgccaatcccatc
aagttcttcagtgcccacgataagaagtctgtgaagctcaaggaagccatgggagctctg
cctgagaaacccttccccactgggagtccagttgccggccaggtcaatgggccattggcc
ccagtgagcaacggatctgcagcagcccgggccagggccggggaggaggccgccaaagaa
gctgcggagccgcagaccgccagcccggaggagctgcaggagctgaagggcgtcgtgaag
ctgcagcggcggcacgagaaggagctccgggacctggagcggcgcggcgcgcggcgccgg
gaggagctgctgcagaggggcgcggcgcagctggccgggctggggccgccgggcgcgggg
ggctgcgggggccgcaggctcggccccgggaagggctcccgcaagaagaggacttcgccc
tgcgacgaggccgccggggccgcgccccaggaggaccgcgagggccccgagggcgcggac
gcgcgtgcgcgcgagctgaaggaccggctggagctggagttgctgcagcagggcgaggag
cagtacgagtgcatcctgaagcgcaaggagcagcacgtggctgagcaaatcgccaagatg
atggagctggccagagagaagcaggctgcagagctgaagaccctcaaggagaccttggag
actgacactaaagagatgaagaaaaagctggaagccaagaggctggagcggattcaggcc
atggtcaaagtcacctcagacaagatggctcaggaaaggctgaagagagagattaacaac
tcccacatccaggaggtggtgcaagtcattaagcagatgacagagagcctggagaagcac
caggagaagctggaggagaagcaggcagcctgcttggaacagatccgggagatggaaaag
cagttccagcaggaggctctggcagagtacgaggccaggatgaagggcttggaggccgag
gtgaaggagtccgtgagggcctgccttaggggctgcttcccctctgaggccaaggacatg
cctgagaggccctgtgaggccttccgggagctgtgtgagcaggacccactcgcagcaaag
gcaggtgcccaggagagccgcctctga

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