KEGG   Canis lupus familiaris (dog): 100856393
Entry
100856393         CDS       T01007                                 
Symbol
TLN1
Name
(RefSeq) talin-1 isoform X4
  KO
K06271  talin
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa04015  Rap1 signaling pathway
cfa04510  Focal adhesion
cfa04611  Platelet activation
cfa04820  Cytoskeleton in muscle cells
cfa05166  Human T-cell leukemia virus 1 infection
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    100856393 (TLN1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100856393 (TLN1)
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    100856393 (TLN1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100856393 (TLN1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100856393 (TLN1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:cfa04147]
    100856393 (TLN1)
Exosome [BR:cfa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   100856393 (TLN1)
  Exosomal proteins of other cancer cells
   100856393 (TLN1)
SSDB
Motif
Pfam: VBS Talin_middle Talin_R4 I_LWEQ FERM_f0 FERM_M FERM_N ACBP IRS TrcR RA SNX17-31_F2_FERM GIT1_C
Other DBs
NCBI-GeneID: 100856393
NCBI-ProteinID: XP_003639438
Ensembl: ENSCAFG00000002154
VGNC: 47401
Position
11:complement(50794867..50827807)
AA seq 2541 aa
MVALSLKISIGNVVKTMQFEPSTMVYDACRIIRERIPEALAGPPSDFGLFLSDDDPKKGI
WLEAGKALDYYMLRNGDTMEYRKKQRPLKIRMLDGTVKTIMVDDSKTVTDMLMTICARIG
ITNHDEYSLVRELMEEKKEEVTGTLRKDKTLLRDEKKMEKLKQKLHTDDELNWLDHGRTL
REQGVEEHETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFAG
FQCQIQFGPHNEQKHKAGFLDLKDFLPKEYVKQKGERKIFQAHKNCGQMSEIEAKVRYVK
LARSLKTYGVSFFLVKEKMKGKNKLVPRLLGITKECVMRVDEKTKEVIQEWSLTNIKRWA
ASPKSFTLDFGDYQDGYYSVQTTEGEQIAQLIAGYIDIILKKKKSKDHFGLEGDEESTML
EDSVSPKKSTVLQQQYNRVGKVEHGSVALPAIMRSGASGPENFQMGSMPPAQQQITSGQM
HRGHMPPLTSAQQALTGTINSSMQAVQAAQATLDDFDTLPPLGQDAASKAWRKNKMDESK
HEIHSQVDAITAGTASVVNLTAGDPAETDYTAVGCAVTTISSNLTEMSRGVKLLAALLED
EGGSGRPLLQAAKGLAGAVSELLRSAQPASAEPRQNLLQAAGNVGQASGELLQQIGESDT
DPHFQDVLMQLAKAVASAAAALVLKAKSVAQRTEDSGLQSQVIAAATQCALSTSQLVACT
KVVAPTISSPVCQEQLVEAGRLVAKAVEGCVSASQAATEDGQLLRGVGAAATAVTQALNE
LLQHVKAHATGAGPAGRYDQATDTILTVTENIFSSMGDAGEMVRQARILAQATSDLVNAI
KADAEGESDLENSRKLLSAAKILADATAKMVEAAKGAAAHPDSEEQQQRLREAAEGLRMA
TNAAAQNAIKKKLVQRLEHAAKQAAASATQTIAAAQHAASTPKASAGPQPLLVQSCKAVA
EQIPLLVQGVRGSQAQPDSPSAQLALIAASQSFLQPGGKMVAAAKASVPTIQDQASAMQL
SQCAKNLGTALAELRTAAQKAQEACGPLEMDSALSVVQNLERDLQEVKAAARDGKLKPLP
GETMEKCAQDLGNSTKAVSSAIAQLLGEVAQGNENYAGIAARDVAGGLRSLAQAARGVAA
LTSDPAVQAIVLDTASDVLDKASSLIEEAKKAAGHPGDPESQQRLAQVAKAVTQALNRCV
SCLPGQRDVDNALRAVGDASKRLLSDSLPPSTGTFQEAQSRLNEAAAGLNQAATELVQAS
RGTPQDLARASGRFGQDFSTFLEAGVEMAGQAPSQEDRAQVVSNLKGISMSSSKLLLAAK
ALSTDPAAPNLKSQLAAAARAVTDSINQLITMCTQQAPGQKECDNALRELETVRELLENP
VQPINDMSYFGCLDSVMENSKVLGEAMTGISQNAKNGNLPEFGEAIATASKALCGFTEAA
AQAAYLVGVSDPNSQAGQQGLVEPTQFARANQAIQMACQSLGEPGCTQAQVLSAATIVAK
HTSALCNSCRLASARTANPTAKRQFVQSAKEVANSTANLVKTIKALDGAFTEENRAQCRA
ATAPLLEAVDNLSAFASNPEFSSIPAQISPEGRAAMEPIVISAKTMLESAGGLIQTARAL
AVNPRDPPRWSVLAGHSRTVSDSIKKLITSMRDKAPGQLECETAIAALNSCLRDLDQASL
AAVSQQLAPREGISQEALHTQMLTAVQEISHLIEPLASAARAEASQLGHKVSQMAQYFEP
LTLAAVGAASKTLSHPQQMALLDQTRTLAESALQLLYTAKEAGGNPKQAAHTQEALEEAV
QMMTEAVEDLTTTLNEAASAAGVVGGMVDSITQAINQLDEGPMGEPEGSFVDYQTTMVRT
AKAIAVTVQEMVTKSNTSPEELGPLANQLTSDYGRLASQAKPAAVAAENEEIGAHIKHRV
QELGHGCAALVTKAGALQCSPSDAYTKKELIECARRVSEKVSHVLAALQAGNRGTQACIT
AASAVSGIIADLDTTIMFATAGTLNREGAETFADHREGILKTAKVLVEDTKVLVQNAAGS
QEKLAQAAQSSVATITRLADVVKLGAASLGAEDPETQVVLINAVKDVAKALGDLISATKA
AAGKVGDDPAVWQLKNSAKVMVTNVTSLLKTVKAVEDEATKGTRALEATTEHIRQELAVF
CSPEPPAKTSTPEDFIRMTKGITMATAKAVAAGNSCRQEDVIATANLSRRAIADMLRACK
EAAYHPEVAPDVRLRALHYGRECANGYLELLDHVLLTLQKPSPELKQQLTGHSKRVAGSV
TELIQAAEAMKGTEWVDPEDPTVIAENELLGAAAAIEAAAKKLEQLKPRAKPKEADESLN
FEEQILEAAKSIAAATSALVKAASAAQRELVAQGKVGAIPANALDDGQWSQGLISAARMV
AAATNNLCEAANAAVQGHASQEKLISSAKQVAASTAQLLVACKVKADQDSEAMKRLQAAG
NAVKRASDNLVKAAQKAAAFEDQENETVVVKEKMVGGIAQIIAAQEEMLRKERELEEARK
KLAQIRQQQYKFLPSELRDEH
NT seq 7626 nt   +upstreamnt  +downstreamnt
atggttgcactttcgctgaagatcagcattgggaatgtggtgaagaccatgcagtttgag
ccatccaccatggtgtatgatgcctgtcgcatcattcgtgagcgcatcccagaggccctg
gctggccctcccagcgactttgggctattcctgtcagatgatgaccccaaaaaaggtata
tggctggaggccgggaaagctttggattactacatgctccgcaatggggacaccatggag
tacaggaagaaacagaggcccctgaaaatccgtatgctcgatggaactgtgaagactatc
atggtggatgactctaagactgtcaccgacatgctcatgaccatctgtgcccgcattggc
atcaccaaccatgatgaatattccctggttcgagagctgatggaagagaaaaaggaggag
gtaacaggaaccttacgaaaagataagacactgctgcgagatgaaaagaagatggagaaa
ctaaagcagaagttgcacacagatgatgagttgaactggctggaccatggccgcacgctg
agggaacagggggtggaggagcatgagacacttctgctgcggaggaagttcttctactca
gaccagaatgtggactcccgggaccctgtacagctgaacctcctttatgtgcaggcacga
gatgacatcctcaatggctcccaccctgtctccttcgacaaggcctgtgagtttgctggc
ttccaatgccagatccagtttgggccccacaatgagcagaagcacaaggctggcttcctt
gacctgaaggacttcctgcccaaggagtatgtgaagcagaagggagagcgtaagatcttc
caggcacacaagaactgtgggcagatgagtgagatcgaggccaaggttcgctacgtgaag
ctagcccgttccctcaagacctatggtgtctccttctttctggtgaaggaaaagatgaaa
ggaaagaacaagctggtgcctagacttctgggcatcactaaggagtgtgtgatgcgggtg
gacgagaagaccaaagaggtgatccaggaatggagcctcaccaacatcaaacgctgggct
gcctctcccaagagcttcaccctggacttcggggactaccaagatggctactactcagta
cagacgacagaaggggagcagatcgcacagctcatcgccggctacatcgatatcatcctt
aagaagaaaaaaagcaaggatcattttgggctggagggagacgaggagtctactatgctg
gaggactcagtttcccccaaaaagtcgacagtcctccagcagcagtataaccgggtgggg
aaggtggagcacggctctgtggccctgcctgctatcatgcgctctggagcctccggtcct
gaaaatttccagatgggcagcatgccaccagcccagcagcagattaccagtggccagatg
caccgaggacacatgccccctttgacgtcagcccagcaggcactcactgggaccattaac
tccagcatgcaggctgtgcaggctgcccaggccactctggatgactttgacactctgccc
cctctgggccaggatgctgcctctaaggcctggcgtaagaacaagatggatgaatcaaag
catgagatccactcccaggtagatgccatcacagccggtactgcctctgtggtgaacctg
acggcgggagaccctgcagagacagactatacagccgtgggctgtgcggtcactaccatc
tcctccaacctcacggagatgtcccgaggcgtgaagctgctggccgccctgctggaggac
gaagggggcagtggccggcccctgctacaggccgccaagggccttgccggggcggtgtca
gagctgctgcgcagcgcccagccagccagcgctgagccccgtcagaacctgctgcaagca
gctgggaacgtgggccaggccagtggggagttgttgcagcaaattggggaaagtgatact
gacccccacttccaggatgtactaatgcagctggctaaggctgtggcaagtgccgcagct
gccttggtcctcaaggccaagagcgtggcccagcggacagaggactcggggcttcagagc
caggtcattgctgcagcaacacagtgcgccttgtccacctcccagctggtggcctgcacc
aaggtggtagcacctacaatcagctcacctgtctgccaggagcagctggtggaggccgga
cgcctggtggccaaagccgtggaaggctgtgtatctgcctcccaggcagccacagaagat
gggcagctgctgcggggggtaggagcagcggccacagctgtcacccaggccctgaatgag
ctgctgcagcatgttaaggcccacgccacaggggccgggcctgctggccgttacgaccag
gccactgacaccatcctcacagtcaccgagaacatcttcagttctatgggcgatgctggt
gagatggtacgacaggcccgcatcttagcccaagccacatctgacctggtcaatgccatc
aaggctgatgccgagggggagagtgatctggagaattctcgcaagctattaagcgctgct
aagatcctggctgatgccacagccaagatggtggaggctgccaagggagcagctgcccac
cctgacagtgaagaacaacagcagcggctgcgggaggcagccgagggcctgcgcatggcg
accaatgcagctgcacagaatgccatcaagaagaagctggtgcagcgcctggagcatgca
gccaaacaggctgcggcctcagctacacagaccattgctgcagcccagcacgcagcctcc
acccccaaggcctctgccggcccccagcccctgctggtgcagagctgcaaggctgtggca
gaacagattccactgctggtgcagggcgtccgagggagccaggctcagcctgacagtccc
agtgctcagctggccctcattgctgcaagccagagctttctacagccaggtgggaagatg
gtggctgctgcaaaagcgtcagtgccaacaattcaggaccaggcttcggccatgcagctg
agtcagtgtgccaaaaaccttggtactgcattggctgaacttcgtactgctgcccagaag
gctcaggaagcgtgtgggcctttggaaatggattctgcactgagcgtggtacagaacctc
gagagagacctgcaggaagtgaaggcagcagctcgagatggcaagcttaagcccttacct
ggggagaccatggagaaatgtgcccaggacctgggtaacagcaccaaagcagtgagctct
gccattgcccagctgctgggggaggttgcccagggcaatgagaattacgcagggatcgcc
gctcgggatgtggcaggtgggctgcggtcactggcccaggctgctcggggtgtagctgcc
ctgacgtcagatcctgcagtgcaggccattgtgcttgacacagccagcgatgttctggac
aaggccagcagcctcatcgaggaagcaaaaaaggcagctggccatccaggggaccccgag
agccagcaacggcttgcccaggtggctaaagctgtgactcaggccctgaaccgctgtgtc
agctgccttcctggccagcgagatgtggacaatgccctgcgagcggtgggagatgccagc
aagcggctcctgagtgactcgcttccacccagcaccgggacatttcaagaagctcagagc
cggttgaatgaggctgccgctgggctgaaccaggcagccacagaactggtacaagcttct
cggggaacccctcaggacctggctcgagcctcaggtcgatttggacaggacttcagcacc
ttcctggaagctggtgtggagatggcaggacaggccccgagccaggaggaccgggcccaa
gtcgtgtccaacttgaagggcatctctatgtcttcgagcaaacttcttctggctgccaag
gccctgtccacagaccctgccgcccccaacctcaagagtcagctggctgcagctgcccgg
gcggtaactgacagcatcaaccagctcatcaccatgtgcacccagcaggcaccaggccag
aaggagtgtgacaatgccctgcgggaattggagacagtccgggaactcctagagaaccca
gttcagcccatcaatgatatgtcctactttggctgcctagacagtgtgatggagaactca
aaggtactaggtgaggccatgactggcatctcccagaatgccaagaacgggaacctgcca
gaatttggggaggccattgccacagcctccaaggccctctgtggcttcaccgaggcagct
gcacaggctgcatatctggtaggtgtctccgatcccaacagccaagctgggcaacaagga
ttggtagagcccacacagttcgcccgtgcaaaccaggcaatccagatggcctgtcagagt
ttgggggagcctggctgtacacaggcccaggtgctctctgcagccaccatcgtggccaag
cacacctctgcgctgtgtaacagctgccgtctagcttctgctcggactgccaaccctacc
gccaagcgccagtttgtacaatctgccaaggaggtggccaacagcacagccaatcttgtc
aagactatcaaggcacttgacggagctttcacagaagagaaccgtgctcagtgccgagca
gcaacagcccctctgctggaggctgtggacaatctgagtgcctttgcatccaaccctgag
ttctccagcattcctgcccagatcagccctgagggccgggctgccatggagcccattgtg
atctctgccaagacaatgttggagagtgccggaggactaatccagaccgctcgagcccta
gcagtcaatccccgggaccccccgcgctggtcagtgctggctggccactcccgtactgtc
tcggactccatcaagaagctcattacaagcatgagggacaaggctccagggcagctggag
tgcgagacagccattgcagctctaaacagctgtctacgggacctagaccaggcttccctt
gctgcagtcagccaacaacttgctccccgtgaaggcatctctcaagaggccttgcacact
cagatgctcactgcagtgcaggagatctcccaccttattgagccactggccagtgctgcg
cgggctgaagcctcccagctgggacacaaggtgtcccagatggcccaatactttgagcca
ctcacactggctgcagtgggtgctgcctccaagaccctgagccacccgcagcagatggca
ctcctggaccagactagaaccttggcagagtctgccttgcagttgctgtacacggccaag
gaggctggcgggaaccccaagcaagcagctcacacccaggaagccctggaggaggctgta
cagatgatgacagaggccgtagaggacctaacaacaaccctcaatgaagcagccagtgct
gctggggttgttggcggcatggtggactccatcacccaggccatcaaccagctagatgaa
ggaccaatgggtgaaccagaaggttcctttgtggattaccaaacaactatggtgcggaca
gccaaggccattgctgtcactgttcaagagatggtaaccaagtcaaacaccagccctgag
gagctaggccctcttgctaatcagctgaccagtgactatggccgcctggcctcacaggcc
aagcctgcagctgtggctgctgagaacgaagagataggtgcccacatcaagcaccgggtg
caagagctggggcatggctgtgctgctctggtcaccaaggcaggcgccctgcagtgcagc
cccagcgacgcctataccaagaaggagctcatagagtgtgcccggagagtctctgagaag
gtctcccacgtgctggctgcgctccaggctgggaaccgtggcacgcaggcctgcatcact
gcagccagcgccgtatctggcatcattgccgaccttgacaccaccatcatgttcgctaca
gctggtaccctcaatcgcgagggtgctgaaactttcgccgaccaccgggagggcatcctg
aagaccgcaaaggtgctggtggaagacaccaaggtcctggtgcagaacgcagccgggagc
caggagaagttagcacaggctgcccagtcctccgtggccaccatcacacggcttgctgat
gtggtcaagctgggtgcagccagcctgggagccgaggaccccgagacacaggtagtgctg
atcaatgcagtgaaagatgtggccaaagccctgggagacctcatcagcgccacaaaggct
gcagctggcaaagttggggacgaccctgctgtgtggcagctcaagaactctgccaaggtg
atggtgaccaatgtgacatcactgcttaagactgtgaaagccgtggaagatgaggctacc
aaaggcacacgggccctggaggcaaccacagaacacatacggcaggagctggcggtcttc
tgttccccagagccacctgctaagacctctaccccagaagattttattcgcatgaccaag
ggtatcaccatggcaacagccaaggctgttgctgctggcaactcctgtcgccaagaggac
gtcatcgccacagccaatctcagtcgtcgtgctatcgcagatatgcttcgcgcttgcaag
gaagcagcttaccacccagaagtggcccctgatgtgcggcttcgagccttgcactatggc
cgggagtgtgccaatggctacctggagctgctggaccatgtgctgctgaccctgcagaag
ccaagcccagagctgaagcagcaattgacaggacactccaagcgtgtggctggttcggtc
actgagctcatccaggctgctgaggccatgaagggaacagaatgggtggacccagaggac
cccacggtcatcgctgagaatgaactcctgggagctgcagccgccatagaggccgcagcc
aaaaagctagagcagctgaagcctcgggccaaacccaaggaggcagatgagtccttaaac
tttgaggagcagatactggaggctgccaagtccatcgcggcagccaccagcgccctggta
aaggcagcatccgctgcccagagggaactagtggcccaagggaaggtgggtgccattcca
gccaatgcactggatgatgggcagtggtcccaaggcctcatttctgctgcccggatggtg
gctgcagccaccaacaatttgtgtgaagccgccaatgcagctgtacaaggccatgccagc
caggagaagcttatctcatcagccaagcaggtggctgcctccacagcccagctccttgtc
gcctgcaaggtcaaggctgaccaggactctgaggcaatgaaacgacttcaggctgctggc
aatgcagtgaagcgagcctcggataacctggtgaaggcagcacagaaggctgcagccttt
gaagaccaagagaacgagacagtggtagtgaaggagaaaatggttgggggcattgcccag
atcattgctgcacaggaagagatgcttcggaaggaacgagagctggaagaggcgcggaag
aagctggcacagattcggcaacagcagtacaagttcctgccttcagagcttcgggatgag
cactag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (5)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   RefGene (12)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (25)   
   RefSeq(pep) (25)   
DNA sequence (25)   
   RefSeq(nuc) (25)   
Protein domain (13)   
   Pfam (13)   
All databases (89)   

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