KEGG   Canis familiaris (dog): 100856745Help
Entry
100856745         CDS       T01007                                 

Gene name
HADHA
Definition
hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
Orthology
K07515  
enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.211]
Organism
cfa  Canis familiaris (dog)
Pathway
Fatty acid elongation
Fatty acid degradation
Valine, leucine and isoleucine degradation
Lysine degradation
Tryptophan metabolism
beta-Alanine metabolism
Propanoate metabolism
Butanoate metabolism
Biosynthesis of unsaturated fatty acids
Metabolic pathways
Carbon metabolism
Fatty acid metabolism
Module
Malonate semialdehyde pathway, propanoyl-CoA => Acetyl-CoA
Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
Fatty acid biosynthesis, elongation, mitochondria
beta-Oxidation
Brite
KEGG Orthology (KO) [BR:cfa00001]
 Metabolism
  Overview
   01200 Carbon metabolism
    100856745 (HADHA)
   01212 Fatty acid metabolism
    100856745 (HADHA)
  Carbohydrate metabolism
   00640 Propanoate metabolism
    100856745 (HADHA)
   00650 Butanoate metabolism
    100856745 (HADHA)
  Lipid metabolism
   00062 Fatty acid elongation
    100856745 (HADHA)
   00071 Fatty acid degradation
    100856745 (HADHA)
   01040 Biosynthesis of unsaturated fatty acids
    100856745 (HADHA)
  Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    100856745 (HADHA)
   00310 Lysine degradation
    100856745 (HADHA)
   00380 Tryptophan metabolism
    100856745 (HADHA)
  Metabolism of other amino acids
   00410 beta-Alanine metabolism
    100856745 (HADHA)
Enzymes [BR:cfa01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.211  long-chain-3-hydroxyacyl-CoA dehydrogenase
     100856745 (HADHA)
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.17  enoyl-CoA hydratase
     100856745 (HADHA)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
17
AA seq 762 aa AA seqDB search
MVASRAIGSLSRATASRMFRCPGYVCRNFTGSSALRSRTHINFGVKGDVAVVRLNSPNSK
VNTLNKELQSEFMEVMNEIWASDQIRSAVLISTKPGCFIAGADINMLASCKTHEEVTRIS
QEGQRMFEKLEKSTKPIVAAISGACLGGGLELAISCQYRIATKDRKTVLGAPEVLLGILP
GAGGTQRLPKMVGLPAAFDMMLTGRNIRADRAKRMGLVDQLVEPLGPGLKPPEERTIEYL
EEVAVNFAKGLSDKKISIKRDKGLVEKLTSYALSIPFVRQQVYKKVEEKVRKQTKGLYPA
PLKIIDVVKTGIEQGNDAGYLSESQKFGELAMTKESKALMGLYHGQVLCKKNKFGAPQKE
VKDLAILGAGLMGAGIAQVSVDKGLKTILKDATLTGLGRGQQQVFKGLNDKVKKKALTSF
ERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPGHCVFASNTSALP
INEIAAASKRPEKVIGMHYFSPVDKMQLLEIITTDKTSKDTTASAVAVGLKQGKVIIVVK
DGPGFYTTRCLAPMMSEVLRILQEGVEPKKLDSLTTSFGFPVGAATLVDEVGVDVAKHVS
EDLGKAFGERFEGGNIELLKEMVSRGFLGRKSGKGFYIYQEGVKTKNVNSDMDGILASLK
VPPKYGVSSDEDIQYRLVTRFVNEAVLCLQEGILATPTEGDIGAVFGLGFPPCLGGPFRF
VDLYGAQKIVDRLRKFEAAYGKQFTPCQLLIDHANSANKFYQ
NT seq 2289 nt NT seq  +upstreamnt  +downstreamnt
atggtggcctcccgagctataggcagcctcagccgcgccactgcctcccggatgttccgc
tgcccaggttatgtatgccgcaactttacagggtcctctgctctgagatctagaacccat
attaactttggagtcaaaggggatgtggctgttgttcgacttaactcgcccaattcaaag
gtaaatacactgaataaagaactacaatcagaattcatggaagtaatgaatgaaatctgg
gctagtgatcaaatcagaagtgctgtccttatctctacgaagccaggctgctttattgca
ggtgctgacatcaacatgttagcttcttgtaagacccatgaagaggtaacacgaatatca
caggaaggacagagaatgtttgagaaacttgagaagtccacaaagcctattgtggctgcc
atcagtggagcctgcttaggaggaggacttgagcttgccatttcctgccaatatagaata
gcaaccaaagatagaaaaacagtattaggtgcccctgaagtcttgctggggatcttacca
ggagcaggaggcacacaaaggctgcccaaaatggtgggtctgcctgctgcttttgacatg
atgttgactggtagaaacattcgtgcagacagagcaaagagaatgggactggttgaccaa
ttagtggaacccctgggaccaggattaaaacctccagaggaacggacaattgaatactta
gaagaagttgcagttaattttgccaaaggactatctgataagaaaatctccataaagaga
gacaagggattagtagaaaaattgacgtcatatgccctgagtattccttttgtcagacaa
caggtttacaaaaaggtggaagaaaaagtacgaaaacagaccaaaggcctttatcctgca
cctctgaaaataatcgatgtggtaaagactggaattgagcaagggaacgatgctggctat
ctctctgaatctcagaaatttggagagcttgcaatgaccaaagaatcaaaggcgttgatg
ggactttatcatggtcaggtcctgtgtaagaagaataaatttggagctccgcagaaagaa
gtaaaggacctagccattcttggtgcagggctgatgggagccggcattgcccaggtctct
gtggataagggcctgaagaccatacttaaagatgctacgctaaccgggctgggccgagga
cagcagcaggtgttcaaaggattgaatgataaagtgaagaagaaagctctaacatcattt
gaaagggactccatttttagcaacttgactgggcagctcgattaccaaggttttgaaaag
gctgacatggtgattgaagctgtttttgaggacctaagtcttaagcacagagtgctaaaa
gaagtggaagcggtgattccaggtcactgtgtctttgccagtaacacatctgctctccca
atcaatgaaattgctgctgccagcaaaagacctgagaaggtgattggcatgcactacttc
tctcctgtggacaagatgcagctactggagattattacaacagataaaacgtctaaggac
accactgcttcagcggtagctgtcgggctcaagcaggggaaggtcatcattgtggtgaaa
gatggacctggcttctacaccaccaggtgccttgcacccatgatgtctgaagtcctcaga
atcctccaggaaggagttgagcctaagaagctggattcccttaccacaagctttggcttt
cctgtgggtgctgccacactggtcgatgaagttggtgtggatgtagcaaaacatgtatca
gaagatctgggcaaagcctttggggaacggtttgaaggtggaaacatagaactgctgaag
gagatggtgtccaggggcttcctgggtcgcaagtctgggaaaggcttttacatctaccag
gagggtgtgaagactaagaatgtgaattctgacatggatggtattttggcaagtctgaag
gtgccccctaagtatggcgtctcctcggatgaagacatccagtaccgcctggtgacaaga
tttgtgaatgaggccgtcctgtgcctgcaggaagggatcttggccacacccacagaggga
gacatcggagcggtgtttgggcttggctttcccccatgtcttggagggcccttccgcttt
gtggatctgtatggtgctcagaagatagtggaccggctcaggaagtttgaggctgcctat
ggaaaacagttcaccccatgtcagctgctcattgaccacgcgaacagtgctaacaagttc
taccagtga

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