KEGG   Canis familiaris (dog): 403556Help
Entry
403556            CDS       T01007                                 

Gene name
PRKACA
Definition
protein kinase, cAMP-dependent, catalytic, alpha (EC:2.7.11.11)
Orthology
K04345  
protein kinase A [EC:2.7.11.11]
Organism
cfa  Canis familiaris (dog)
Pathway
MAPK signaling pathway
Ras signaling pathway
Calcium signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
Oocyte meiosis
Apoptosis
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Wnt signaling pathway
Hedgehog signaling pathway
Gap junction
Platelet activation
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
GABAergic synapse
Dopaminergic synapse
Olfactory transduction
Taste transduction
Inflammatory mediator regulation of TRP channels
Insulin signaling pathway
Insulin secretion
GnRH signaling pathway
Ovarian steroidogenesis
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Endocrine and other factor-regulated calcium reabsorption
Vasopressin-regulated water reabsorption
Salivary secretion
Gastric acid secretion
Bile secretion
Parkinson's disease
Prion diseases
Cocaine addiction
Amphetamine addiction
Morphine addiction
Amoebiasis
HTLV-I infection
Epstein-Barr virus infection
Viral carcinogenesis
Proteoglycans in cancer
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:cfa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    403556 (PRKACA)
   04010 MAPK signaling pathway
    403556 (PRKACA)
   04310 Wnt signaling pathway
    403556 (PRKACA)
   04340 Hedgehog signaling pathway
    403556 (PRKACA)
   04020 Calcium signaling pathway
    403556 (PRKACA)
   04024 cAMP signaling pathway
    403556 (PRKACA)
 Cellular Processes
  Cell growth and death
   04114 Oocyte meiosis
    403556 (PRKACA)
   04210 Apoptosis
    403556 (PRKACA)
  Cellular commiunity
   04540 Gap junction
    403556 (PRKACA)
 Organismal Systems
  Immune system
   04611 Platelet activation
    403556 (PRKACA)
   04062 Chemokine signaling pathway
    403556 (PRKACA)
  Endocrine system
   04911 Insulin secretion
    403556 (PRKACA)
   04910 Insulin signaling pathway
    403556 (PRKACA)
   04912 GnRH signaling pathway
    403556 (PRKACA)
   04913 Ovarian Steroidogenesis
    403556 (PRKACA)
   04915 Estrogen signaling pathway
    403556 (PRKACA)
   04914 Progesterone-mediated oocyte maturation
    403556 (PRKACA)
   04921 Oxytocin signaling pathway
    403556 (PRKACA)
   04918 Thyroid hormone synthesis
    403556 (PRKACA)
   04919 Thyroid hormone signaling pathway
    403556 (PRKACA)
   04916 Melanogenesis
    403556 (PRKACA)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    403556 (PRKACA)
   04270 Vascular smooth muscle contraction
    403556 (PRKACA)
  Digestive system
   04970 Salivary secretion
    403556 (PRKACA)
   04971 Gastric acid secretion
    403556 (PRKACA)
   04976 Bile secretion
    403556 (PRKACA)
  Excretory system
   04962 Vasopressin-regulated water reabsorption
    403556 (PRKACA)
   04961 Endocrine and other factor-regulated calcium reabsorption
    403556 (PRKACA)
  Nervous system
   04724 Glutamatergic synapse
    403556 (PRKACA)
   04727 GABAergic synapse
    403556 (PRKACA)
   04725 Cholinergic synapse
    403556 (PRKACA)
   04728 Dopaminergic synapse
    403556 (PRKACA)
   04726 Serotonergic synapse
    403556 (PRKACA)
   04720 Long-term potentiation
    403556 (PRKACA)
   04723 Retrograde endocannabinoid signaling
    403556 (PRKACA)
  Sensory system
   04740 Olfactory transduction
    403556 (PRKACA)
   04742 Taste transduction
    403556 (PRKACA)
   04750 Inflammatory mediator regulation of TRP channels
    403556 (PRKACA)
  Environmental adaptation
   04713 Circadian entrainment
    403556 (PRKACA)
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    403556 (PRKACA)
   05203 Viral carcinogenesis
    403556 (PRKACA)
  Neurodegenerative diseases
   05012 Parkinson's disease
    403556 (PRKACA)
   05020 Prion diseases
    403556 (PRKACA)
  Substance dependence
   05030 Cocaine addiction
    403556 (PRKACA)
   05031 Amphetamine addiction
    403556 (PRKACA)
   05032 Morphine addiction
    403556 (PRKACA)
  Cardiovascular diseases
   05414 Dilated cardiomyopathy (DCM)
    403556 (PRKACA)
  Infectious diseases
   05166 HTLV-I infection
    403556 (PRKACA)
   05169 Epstein-Barr virus infection
    403556 (PRKACA)
   05146 Amoebiasis
    403556 (PRKACA)
Enzymes [BR:cfa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     403556 (PRKACA)
Protein kinases [BR:cfa01001]
 Serine/threonine protein kinases: AGC group
  PKA family
   403556 (PRKACA)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
20
AA seq 350 aa AA seqDB search
MGNAAAKKGSEQESVKEFLAKAKEDFLKKWENPAQNTAHLDQFERIKTLGTGSFGRVMLV
KHKETGNHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVM
EYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYI
QVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFA
DQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATT
DWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFCEF
NT seq 1053 nt NT seq  +upstreamnt  +downstreamnt
atgggcaacgccgccgccaagaagggcagcgagcaggagagcgtgaaagagttcttagcc
aaagccaaagaagactttcttaaaaaatgggaaaatcctgctcagaatacagcccatttg
gatcagtttgaacgaatcaagaccctcggcacgggctcctttgggcgggtgatgctggtg
aagcacaaggagaccgggaaccactttgccatgaagatcctcgacaaacagaaggtcgtg
aagctgaaacagattgagcataccctgaacgaaaagcgcatcctgcaagcggtcaacttc
ccgttcctcgtcaaactcgagttctccttcaaggacaactcgaatttatacatggtcatg
gagtatgtgcctggcggggagatgttctcgcacctgcggcggatcggaaggttcagtgaa
ccgcatgcccgcttctatgcggcccagatcgtcctgaccttcgagtacctgcactcactt
gacctcatctaccgggacctgaagccggagaacctcctcattgaccagcagggctacatt
caggtgacagacttcggttttgccaagcgtgtaaaaggccgcacctggaccttatgcggg
acccccgagtacctggccccggaaatcatcctgagcaaaggctacaacaaggctgtggac
tggtgggccctaggggttctcatctacgagatggccgctggctacccacccttctttgct
gaccagcccatccagatctatgagaagattgtctctgggaaggtgcggttcccgtcccac
ttcagctctgacctgaaggatctgctacggaacctgttgcaggtggacctcaccaaacgc
ttcgggaacctcaagaatggggtgaacgatatcaagaaccacaagtggtttgccacaact
gactggatcgccatctatcagaggaaggtggaagctcccttcataccaaagtttaaaggc
cctggggacacgagtaattttgacgactatgaggaggaagagatccgagtctccatcaat
gagaagtgtggcaaggagttttgtgagttctag

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