KEGG   Canis familiaris (dog): 442860Help
Entry
442860            CDS       T01007                                 

Gene name
PDGFRA
Definition
platelet-derived growth factor receptor, alpha polypeptide
Orthology
K04363  
platelet-derived growth factor receptor alpha [EC:2.7.10.1]
Organism
cfa  Canis familiaris (dog)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Calcium signaling pathway
Cytokine-cytokine receptor interaction
Endocytosis
PI3K-Akt signaling pathway
Focal adhesion
Gap junction
Regulation of actin cytoskeleton
HTLV-I infection
Pathways in cancer
MicroRNAs in cancer
Glioma
Prostate cancer
Melanoma
Brite
KEGG Orthology (KO) [BR:cfa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    442860 (PDGFRA)
   04015 Rap1 signaling pathway
    442860 (PDGFRA)
   04010 MAPK signaling pathway
    442860 (PDGFRA)
   04020 Calcium signaling pathway
    442860 (PDGFRA)
   04151 PI3K-Akt signaling pathway
    442860 (PDGFRA)
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    442860 (PDGFRA)
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    442860 (PDGFRA)
  Cell motility
   04810 Regulation of actin cytoskeleton
    442860 (PDGFRA)
  Cellular commiunity
   04510 Focal adhesion
    442860 (PDGFRA)
   04540 Gap junction
    442860 (PDGFRA)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    442860 (PDGFRA)
   05206 MicroRNAs in cancer
    442860 (PDGFRA)
   05214 Glioma
    442860 (PDGFRA)
   05218 Melanoma
    442860 (PDGFRA)
   05215 Prostate cancer
    442860 (PDGFRA)
  Infectious diseases
   05166 HTLV-I infection
    442860 (PDGFRA)
Enzymes [BR:cfa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     442860 (PDGFRA)
Protein kinases [BR:cfa01001]
 Tyrosine protein kinases
  PDGFR family [OT]
   442860 (PDGFRA)
Enzyme-linked receptors [BR:cfa01020]
 Receptor tyrosine kinases
  RTK class III (PDGF receptor family)
   442860 (PDGFRA)
Cytokine receptors [BR:cfa04050]
 Receptor tyrosine kinase
  RTK class III (PDGF receptor family)
   442860 (PDGFRA)
Cellular antigens [BR:cfa04090]
 Proteins
  442860 (PDGFRA)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
13
AA seq 1114 aa AA seqDB search
MLPMDERHFWGGSQSLLGDRKFSGTMGTSLLALLILGCLLAGPSLILCQLSLPSILPNEN
EKVVQLNSSFSLRCFGESEVSWHYPTSEEENPNVEIRNEENNSGLFVTVLEVVNASAAHT
GLYTCYYNHTQTDENEIEGRHIYIYVPDPDVAFVPLGMTDYLVIVEDDDSAIIPCRTTDP
ETPVTLLSNDGVVHASYDSRQGFNGTFSVGPYICEATVRGKKFQTIPFNVYALKATSELD
LEMEALKTVYKSGETIVVTCAVFNNEVVDLQWTYPGEVKGKGITMLEEIKVPSIKLVYTL
RVPEATVKDSGDYECAARQATKEVKEMKKVTISVHEKGFIEIKPNFSQLEAVDLHEVKHF
VVDVQAYPPPRISWLKDNLTLIENLTEITTDIERTQEIRYRSKLKLIRAKEEDSGHYTIV
VQNEDDVKSYTFELLTQVPSSILDLVDDHHGSTGGQTVRCIAEGTPLPDIEWMICKDIKK
CNNETSWAILANNISNIITEVHPRDRSTVEGRVTFTRVEETIAVRCLAKNLLGAESRELK
LVAPTLRSELTVAAAVLVLLVIVIISLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYV
DPMQLPYDSRWEFPRDGLVLGRILGSGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARS
SEKQALMSELKIMTHLGPHLNIVNLLGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFLS
RHPEKPKKELDIFGLNPADDSTRSYVILSFENNGDYMDMKQADTTQYVPMLERKEVSKYS
DIQRSLYDRPASYKKKSMLDSEVKNLLSDDNSEGLTLLDLLSFTYQVARGMEFLASKNCV
HRDLAARNVLLAQGKIVKICDFGLARDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTL
SDVWSYGILLWEIFSLGGTPYPGMMVDSTFYNKIKSGYRMAKPDHATSEVYEIMVKCWHS
EPEKRPSFYHLSEIVENLLPGQYKKSYEKIHLDFLKSDHPAVARMRVDSDNAYIGVTYKN
EEDKLKDWEGSLDEQRLSADSGYIIPLPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSS
SSTFIKREDETIEDIDMMDDIGIDSSDLVEDSFL
NT seq 3345 nt NT seq  +upstreamnt  +downstreamnt
atgttgccgatggacgagcggcacttctggggggggagccaaagcctgctcggggaccga
aagttttccggaactatggggacttcccttctggcactcctgatcttaggctgtctcctc
gcagggcccagcctaatcctctgccagctttcattaccctcgatccttccaaatgaaaat
gaaaaggtcgtgcagctgaattcatccttttctctgagatgctttggggagagtgaagtg
agttggcattaccccacgtctgaagaagagaaccccaatgtggagatcagaaatgaggag
aacaacagtggcctttttgtgaccgtgttggaagtggtcaacgcgtcggcggcgcacacg
gggctgtacacttgctattacaaccacactcagacagacgaaaacgagatcgaaggcagg
cacatctacatctatgtgccagacccggatgtcgccttcgtacctctaggaatgacagat
tatttagtcatcgtggaggatgatgactctgccatcataccttgtcgtacaactgatcct
gagactccggtcaccttactcagcaatgatggggtggtacatgcgtcctatgacagcaga
cagggctttaatgggaccttcagcgttgggccgtatatctgcgaagccactgtcaggggc
aagaagttccagaccatcccatttaatgtttatgctttaaaagcaacgtcagaacttgat
ctagaaatggaagctcttaaaactgtgtataagtcaggggagacgattgtggtcacctgc
gccgtctttaacaacgaggtggtggaccttcaatggacctaccctggagaggtgaaaggc
aaaggcatcaccatgttggaggaaataaaggtcccgtccatcaaattggtgtacactctg
agggtccccgaggccacggtgaaagatagtggagattatgaatgtgctgcccgccaggcc
accaaggaagtcaaagagatgaagaaagtcaccatttctgtccatgagaaagggttcatt
gaaatcaaacccaacttcagccagttggaagctgttgacctacacgaagtcaagcatttc
gtggtggacgtgcaggcctacccacctcccaggatatcctggctgaaggacaacctgact
ctgattgaaaatctcacagagatcaccactgacatagaaaggactcaggaaataaggtat
cgaagcaaattaaagctgatccgtgctaaggaggaggacagtggccattacactatcgtc
gttcaaaatgaggatgacgtcaagagctatactttcgaactcttaactcaagttccctcg
tctattctggacttggtcgatgaccaccacggctctactgggggacagaccgtgagatgc
atcgctgaagggacacctcttcctgatattgaatggatgatttgcaaggatattaagaaa
tgtaataatgaaacctcctgggcgattttggccaacaatatctcaaacattatcacggag
gtccacccccgagacaggagtactgtggagggccgggtgaccttcaccagagtggaggag
accatcgccgttcgatgtctggccaagaatctccttggggccgagagccgagagctgaag
ctggtggctcccacgctgcgttctgagctcacggtggcagctgcagtcctggtgctattg
gtgattgtgatcatctcacttatcgtcctggttgtcatttggaaacagaaaccgaggtat
gaaattcgttggagggtcattgaatccatcagccctgatggacatgaatatatttacgtg
gacccgatgcagctgccttatgactcaagatgggagtttccaagagatggacttgtgctt
ggtcggatcctgggatctggtgcgtttgggaaagtggttgaaggaactgcctatggatta
agccgctcccagccggtcatgaaagtcgcagtgaagatgctgaaacccacagccagatcc
agtgaaaaacaagctctcatgtcggaactgaagataatgactcacctggggccgcattta
aacattgtgaacttgctgggagcctgtaccaagtcaggccccatttacatcatcaccgag
tactgcttctatggggatttggtcaactatttgcataagaatagagatagcttcctgagc
cgccacccggagaagccaaagaaagagttggacatttttggattgaaccctgctgatgac
agcacacggagttacgttattttgtcttttgaaaacaacggtgactacatggacatgaag
caagctgacaccacacagtatgtccccatgctggaaaggaaagaggtttctaagtactcg
gacatccagagatcgctgtatgatcgtccagcctcgtacaagaagaaatctatgttagac
tccgaagtcaaaaacctcctttcggatgataactcagaaggccttactttgttggatttg
ttgagcttcacctatcaagttgcgcgaggaatggagtttttggcttcgaaaaattgtgtc
caccgggacctggctgctcgaaacgtcctcctggcacaagggaaaatcgtgaagatctgc
gacttcggcctggccagagacatcatgcacgattcaaactatgtgtctaaaggcagtacc
tttctccccgtgaagtggatggctcccgagagcatcttcgacaacctctacaccacgctg
agtgacgtctggtcctacggcatcctgctctgggagatcttttcccttggcggcacaccc
taccctggcatgatggtggattctactttctacaataagatcaagagtggataccggatg
gccaagcctgaccacgccaccagtgaagtctatgagatcatggtgaagtgctggcacagt
gaaccggagaagagaccctccttttaccacctgagcgagatcgtggagaatctgctgcct
ggacaatataagaagagttacgagaagattcacctggacttcctgaagagcgaccacccc
gccgtggcgcgtatgcgcgtggactcagacaacgcctacatcggcgtcacctacaaaaac
gaggaggacaagctgaaggactgggagggcagcctggacgagcagaggctgagcgccgac
agcggctacatcatccccctgcccgacatcgacccggtgcccgaggaggaagacctgggc
aagaggaacagacacagctcgcagacctcagaagaaagcgctatcgagacaggttccagc
agctctaccttcatcaagagagaggacgaaaccatcgaggacatcgacatgatggacgac
attggaatagactcctcagacctggtagaggacagcttcctgtga

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