KEGG   Canis familiaris (dog): 475253Help
Entry
475253            CDS       T01007                                 

Gene name
ITGB8
Definition
integrin, beta 8
Orthology
K06591  
integrin beta 8
Organism
cfa  Canis familiaris (dog)
Pathway
PI3K-Akt signaling pathway
Focal adhesion
ECM-receptor interaction
Cell adhesion molecules (CAMs)
Regulation of actin cytoskeleton
Hypertrophic cardiomyopathy (HCM)
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:cfa00001]
 Environmental Information Processing
  Signal transduction
   04151 PI3K-Akt signaling pathway
    475253 (ITGB8)
  Signaling molecules and interaction
   04512 ECM-receptor interaction
    475253 (ITGB8)
   04514 Cell adhesion molecules (CAMs)
    475253 (ITGB8)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    475253 (ITGB8)
  Cellular commiunity
   04510 Focal adhesion
    475253 (ITGB8)
 Human Diseases
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    475253 (ITGB8)
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    475253 (ITGB8)
   05414 Dilated cardiomyopathy (DCM)
    475253 (ITGB8)
Exosome [BR:cfa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   475253 (ITGB8)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
UniProt: 
Position
14
AA seq 779 aa AA seqDB search
MCRSALAFFAAAFVRLQNCRPGPAPFLRAAWVLLVVLGLGQSEDNRCTSSNAASCTKCLA
LGPECGWCAQEDFISGGLRSERCDIISNLISKGCSTDSIEYPSVHVIPSENEINTQVTPG
EVLIQLRPEAEANFMLKIHPLKKYPVDLYYLVDVSASMHNNIEKLNSVGNDLSRKMAYFS
RDFRLGFGSYVDKTVSPYISIHPERIHNQCSDYNLDCMPPHGYIHVLSLTENITEFEKAV
HRQKISGNIDTPEGGFDAMLQAAVCESHIGWRKEAKRLLLVMTDQTSHLALDSKLAGIVV
PNDGNCHLKNNIYVRSTSMEHPSLGQLSEKLIDNNINVIFAVQGKQFHWYKDLLPLLPGT
IAGEIESKAANLNNLVIDAYQKLISEVKVQVENQVKGVYFNITAICPDGTRKPGTDGCGN
VTSNDEVLFNVTVTMKKCDVTGGKSYAIIKPIGFNETTKIHIHRNCSCQCDDGRGSKRKC
VDEIFLDAKCFQCNENKCHFDEAQFPSETCKSHKDQPVCSGRGVCVCGKCLCHKVKFGKV
YGKYCEKDDFSCPYHHGNLCAGHGECEAGRCQCFSGWEGDRCQCPSASAQHCVNPKGQVC
SGRGTCVCGRCECTDPGSIGRFCEHCPTCHTACSENWNCVQCLRPHNLSQAILDRCKTSC
ALMEQHYMEQTSECFSSPSYLRIFFIIFIVTFLIGLLKVLIIRQVILQWNSNKIKSSADY
RVSASKKDKLILQSVCTRAVTYRREKPEEIKMDISKLNAHETFRRRQTVLDHAGCWLST
NT seq 2340 nt NT seq  +upstreamnt  +downstreamnt
atgtgccgctccgctctggctttttttgccgccgcatttgtccgcctgcaaaactgccgg
ccgggtccagccccgttccttcgggcggcctgggtgcttttagttgttcttggactgggc
caaagtgaagacaatagatgtacatcttcaaatgcagcatcctgcaccaaatgccttgcg
ctgggtccggaatgtggatggtgtgctcaagaggatttcatttcaggtggattaaggagt
gaacgttgtgatattatttccaacttaataagcaaaggctgttcgactgattcaatagaa
tacccatctgtacatgtaataccaagtgaaaatgaaattaatacccaggtgacaccagga
gaagtgttgatccagctgcgtccagaagctgaagctaattttatgctgaaaattcatcct
ctgaagaaatatcctgtggatctttattacctggttgatgtctcagcatcaatgcacaat
aatattgaaaaattaaattccgttggaaatgatttatctagaaaaatggcatatttttcc
cgtgacttccgtcttggatttggctcctatgttgataaaacagtttcaccatacattagc
atccacccagaaaggattcataatcaatgcagtgactacaatttagattgtatgcctcct
catggatacatccatgtgctatctttgacggagaacattactgagtttgaaaaagcagtt
cacagacaaaagatctctggaaacatagatacacctgaaggaggttttgatgccatgctt
caggcagctgtctgtgagagtcatattggatggcgaaaagaagctaaaagattgctgctg
gtgatgacagatcagacatctcatcttgctcttgatagcaaattggcaggaatagtggtg
ccaaatgatggaaactgccatctcaaaaacaacatctacgtcagatcaacaagcatggaa
catccctcactaggccaactttctgaaaagttaatagacaacaacattaatgtcatcttt
gcagttcaaggaaaacagtttcactggtataaggatcttctacccctcttgcctggcacc
atcgctggtgaaatagaatcaaaggctgcaaacttaaataatttggtaatagatgcctat
cagaaactcatttcagaagtgaaagttcaggtggaaaaccaggtaaaaggagtttatttt
aatattactgccatctgtccagatgggacccgaaaaccaggcacagacggatgtggaaat
gtgacaagcaatgacgaagttcttttcaatgtaacagttacaatgaaaaaatgtgatgtc
acaggaggaaagagctatgcaataatcaaacctattggtttcaatgaaaccactaaaatt
cacatacacagaaactgcagctgtcagtgtgatgatgggagaggatctaaacgaaagtgt
gtagatgaaatttttctagatgccaagtgtttccagtgtaatgagaataaatgtcatttt
gatgaggctcaatttccttctgagacttgcaaatcacacaaggatcaacctgtttgcagt
ggacgaggagtttgtgtttgtggaaaatgtttatgtcacaaagtaaagtttggaaaagtg
tatggaaaatactgtgagaaggatgatttctcttgtccatatcaccatggaaatctgtgt
gctgggcatggagagtgtgaagcgggcagatgccagtgcttcagtggctgggaaggggat
cggtgccagtgcccgtcagcatcagcccagcactgtgtcaatccaaagggccaagtgtgt
agtggaagaggtacatgtgtatgtggcaggtgtgagtgcaccgatcctgggagcattggc
cgcttctgtgaacactgccccacgtgtcacacagcctgcagtgaaaactggaattgtgtg
caatgccttcgccctcacaacctgtctcaagctatacttgatcgttgtaaaacctcatgt
gctcttatggaacagcattatatggagcaaacatcagaatgtttctctagcccaagctat
ttaagaatatttttcatcatcttcatagttacattcttgattgggttgcttaaagtcctt
atcattaggcaggtgatactacaatggaatagtaataaaattaagtcctcggcggattac
agggtgtcagcctcaaaaaaggacaagttgattctgcaaagcgtttgcacaagagcagta
acctaccgacgtgagaaacctgaagaaataaaaatggatatcagcaagttaaatgctcat
gaaactttcaggaggagacaaactgttctagatcatgctggttgctggttgtccacttga

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