KEGG   Canis lupus familiaris (dog): 477064
Entry
477064            CDS       T01007                                 
Symbol
PIK3R4
Name
(RefSeq) phosphoinositide 3-kinase regulatory subunit 4
  KO
K08333  phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa04136  Autophagy - other
cfa04140  Autophagy - animal
cfa04371  Apelin signaling pathway
cfa05010  Alzheimer disease
cfa05014  Amyotrophic lateral sclerosis
cfa05016  Huntington disease
cfa05017  Spinocerebellar ataxia
cfa05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    477064 (PIK3R4)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    477064 (PIK3R4)
   04136 Autophagy - other
    477064 (PIK3R4)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    477064 (PIK3R4)
   05014 Amyotrophic lateral sclerosis
    477064 (PIK3R4)
   05016 Huntington disease
    477064 (PIK3R4)
   05017 Spinocerebellar ataxia
    477064 (PIK3R4)
   05022 Pathways of neurodegeneration - multiple diseases
    477064 (PIK3R4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cfa01001]
    477064 (PIK3R4)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:cfa04131]
    477064 (PIK3R4)
Enzymes [BR:cfa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     477064 (PIK3R4)
Protein kinases [BR:cfa01001]
 Serine/threonine kinases: Other
  VPS15 family
   477064 (PIK3R4)
Membrane trafficking [BR:cfa04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    477064 (PIK3R4)
 Autophagy
  Autophagosome formation proteins
   PI3K complex
    477064 (PIK3R4)
SSDB
Motif
Pfam: Pkinase WD40 HEAT PK_Tyr_Ser-Thr NBCH_WD40 TCAD9 APH
Other DBs
NCBI-GeneID: 477064
NCBI-ProteinID: XP_005634468
Ensembl: ENSCAFG00000006049
VGNC: 44561
UniProt: A0A8C0T4J1
Position
23:complement(27876020..27947053)
AA seq 1358 aa
MGNQLAGIAPSQILSVESYFSDIHDFEYDKSLGSTRFFKVARAKHREGLVVVKVFAIQDP
TLPLTSYKQELEELKIRLHSAQNCLPFQKAVEKASEKAAMLFRQYVRDNLYDRISTRPFL
NNIEKRWIAFQILTAVDQAHKSGVRHGDIKTENVMVTSWNWVLLTDFASFKPTYLPEDNP
ADFNYFFDTSRRRTCYIAPERFVDGGLFATELEYMRDPSTPLVDLNSNQRTRGELKRAMD
IFSAGCVIAELFTEGVPLFDLSQLLAYRNGQFFPEQVLNKIEDRSIRELVTQMIHREPDK
RLGAEDYLKQQRGNAFPEIFYTFLQPYMAQFAKETFLSADERILVIRKDLGNIIHNLCGH
DLPEKAEGEPKENGLVILVSVITSCLQTLKYCDSKLAALELILHLAPRLSVEILLDRITP
YLLHFSNDSVPRVRAEALRTLTKVLALVKEVPRNDVNIYPEYILPGIAHLAQDDATIVRL
AYAENIALLAETALRFLELVQLKNLNMENDPNSEEIGEVTHPNGNYDTELQALHEMVQQK
VVTLLSDPENIVKQTLMENGITRLCVFFGRQKANDVLLSHMITFLNDKNDWHLRGAFFDS
IVGVAAYVGWQSSSILKPLLQQGLSDAEEFVIVKALNALTCMCQLGLLQKPHVYEFASDI
APFLCHPNLWIRYGAVGFITVVAHQISTADVYCKLMPYLEPYITQPIIQIERKLVLLSVL
KEPVSRSIFDYALRSKDITSLFRHLHMRQKKRNGSLPDCPPPEDPAIAQLLKKLLSQGMT
EEEEDKLLALKDFMMKSNKAKANIVDQSHLHDSSQKGVIDLAALGITGRQVDLVKTKQEP
DDKRARKHVKQDSNVNEEWKSMFGSLEPPNIPQALPKGSEQEVIQTGKPPRSESSAGICV
PLSTSPQLPEVTNVQNRKPAIQVLSSAILPSTYQIRITTCKTELQQLIQQKREQCNAERI
AKQMMENAEWESKPPPPGWRPKGLLVAHLHEHKSAVNRIRVSDEHSLFATCSNDGTVKIW
NSQKMEGKTTTTRSTLTYSRIGGRVKTLTFCQGSHYLAIASDNGAVQLLAIEASKLPKSP
KIQPLQSRILDQKDDGCVVDMHHFNSGAQSVLAYATVNGSLVGWDLRSSSNAWTLKHDLK
SGLITSFAVDIHQCWLCIGTSSGTMACWDMRFQLPISSHCHPSRARIRRLSMHPHYQSWV
IAAVQGNNEVSMWDMETGDRRFTLWASSAPPLSELQPSPHSVHGIYCSPADGNPILLTAG
SDMKIRFWDLAYPERSYIVAGSTSSSSVSYYRKIIEGTEVVQEIQNKQKVGPSDDTPRKG
PESLPVGHHDIITDVATFQTTQGFIVTASRDGIVKVWK
NT seq 4077 nt   +upstreamnt  +downstreamnt
atgggaaatcagcttgctggcattgctccttcccagatcctttctgtggagagttatttc
tcagacatccatgactttgaatatgataagagcctgggaagcactcggttttttaaagtt
gctcgagcgaagcaccgagaaggcctggtggttgtgaaggtctttgcaattcaggatccc
acattgcctttaaccagctataaacaagagctggaggaactgaaaatcaggcttcattct
gcacagaactgtctgccttttcagaaagcagtggaaaaagcatctgagaaagcagccatg
ctctttaggcagtatgtgcgagacaacctctatgatcgcatcagtacccgtcccttctta
aataacattgagaagcgttggattgctttccagatcctgacagctgtggaccaagcacac
aaatctggagtccgtcatggggacatcaagactgagaacgttatggtcaccagttggaat
tgggtcctcctaactgattttgcaagttttaagcccacttaccttccggaggacaaccca
gcagatttcaactatttctttgacacttcacgtaggagaacttgctatattgctcctgaa
cgttttgttgatggtggattgtttgctactgagttagaatatatgagggatccttcaact
ccacttgtagacttaaatagtaatcagagaacaagaggagagttgaagcgcgcaatggat
atcttttcagcaggttgtgttatagctgaactttttacagaaggtgtaccactgtttgat
ctctctcaacttctcgcttatagaaatggacagtttttcccggaacaagtgctaaataaa
attgaagatcgcagtatcagagaattggtaactcagatgattcaccgtgagccagataaa
cgtttaggggcagaagattacctaaagcagcagcgtggcaatgcctttcctgaaatattt
tacacattccttcagccctacatggcccagtttgccaaggaaacctttctttctgcagat
gagcgcattctggttatacggaaggatttgggcaacattattcacaatctctgtggacat
gatctgccagaaaaagcagaaggagagcctaaggaaaatgggctggttatcttggtgtct
gttataacgtcctgtctgcagacccttaaatactgtgattccaaacttgctgctttggaa
cttattctccatttggccccaagattaagtgtagaaattcttttggatcgtattactcca
tatcttttgcatttcagcaatgactctgttcctagagtgagggctgaagccttgaggacg
ttgaccaaagttcttgctcttgtcaaagaggttcctcgcaatgatgtcaatatatacccg
gaatatattcttccaggcatagcccacttagcccaagatgatgctactattgttagacta
gcctatgctgaaaacatagctctgctggcagaaacagctttgagattcctggaattagta
cagttaaaaaatctcaatatggaaaatgacccaaatagtgaagaaatcggtgaagttacg
catcccaatggaaattatgacacagagttgcaagccttacatgaaatggtccagcagaaa
gttgtcactttgctaagtgaccctgaaaatattgtgaaacaaaccttaatggaaaatgga
ataacacggttgtgtgtattctttggacgtcagaaagccaatgatgttttattgtcccac
atgatcactttcctaaatgataagaatgattggcatctgcgtggagctttttttgatagt
atagttggtgttgctgcctatgttggttggcaaagctcctcaattctcaaacccctgctg
caacaaggtcttagtgatgctgaggaatttgttattgttaaagctcttaatgcccttacc
tgtatgtgccagttagggctgctacaaaaaccccatgtctatgaatttgccagtgatatt
gccccatttctgtgtcatcccaatctatggatacgctatggtgccgtaggatttatcaca
gtggtagctcatcaaataagtacagctgatgtatattgcaaactgatgccttaccttgag
ccatatattactcaaccaataatacagattgaaaggaaacttgttctactcagtgtttta
aaagagccagtaagtcggtctatatttgattatgctttgaggtctaaagatattactagt
ttgttcagacatcttcacatgcgccagaagaaacgaaatggatctcttcctgactgccct
ccaccagaggatcctgccatagcacagcttctgaagaaattactctcacagggaatgaca
gaagaagaagaagataaacttttggcactgaaagacttcatgatgaaatctaacaaagca
aaggccaatatagttgaccagagccatcttcatgatagtagtcagaaaggtgtaattgac
ttagcagcattaggtataactgggagacaagttgatctcgttaaaaccaaacaggaacct
gatgacaaacgagctagaaaacatgtaaaacaagactcaaatgtaaatgaagaatggaaa
agcatgtttggatcactggaaccaccgaacatcccacaggctctacctaaagggagtgaa
caggaggtgattcagactgggaaaccacctcgttctgagtcctctgctgggatttgtgtc
cctctgtcaacttctccacagcttccagaagtgacaaatgtccaaaatagaaaaccagca
atacaagttttaagtagtgcgattttaccatctacctaccagattcggatcacaacttgt
aaaacagaacttcagcagctcatacagcaaaagcgggagcagtgtaacgctgagaggata
gctaaacaaatgatggaaaatgctgaatgggagagtaaaccaccaccacctgggtggcgt
cctaaagggctactagttgcacatctccatgaacacaaatctgctgtaaatcgaattaga
gtctctgatgaacattcactttttgcaacatgttcaaacgatggcacggtgaaaatctgg
aatagtcaaaagatggaggggaagaccaccactaccagatctactcttacatatagccga
attggaggacgtgtcaagacacttacattctgccaggggtcccactacttagccattgca
tccgacaatggtgccgttcagcttcttgcaattgaagcttctaagcttcccaagtctcct
aagattcagcctctgcaaagcagaattctagatcagaaggatgatggctgtgttgtggat
atgcatcacttcaactccggggcacagtctgttctggcctatgccactgtgaatggctct
ctagttggttgggacctcaggtcttcaagcaatgcatggacactaaagcacgatctgaag
tcaggcctcatcacttcttttgctgtggacatccatcagtgctggctctgcattggtaca
agcagcggtactatggcttgttgggacatgaggttccagttgccaatttccagtcactgt
catccttccagggctcgaatcagacgcctctcaatgcaccctcattatcagtcctgggtg
attgcagctgtgcagggcaacaatgaagtatccatgtgggacatggagactggcgacaga
agattcactctctgggctagcagtgcaccaccactctctgagttacagccttctcctcac
agtgtccatggtatctactgtagtcctgcagatggaaatcccatccttctaacagctggc
tcagacatgaaaataaggttttgggacttggcttaccccgagaggtcctatattgttgca
ggaagtactagttcttcatctgtatcgtactataggaaaataattgaaggcactgaagtt
gtccaggagatccagaataagcagaaagtaggaccgagtgatgacaccccacggaagggc
ccagaatctctgcctgtgggacaccatgatatcatcacagatgtggccacgttccagaca
acacagggcttcattgtaactgcatctagagatggaattgttaaggtgtggaaatga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (8)   
   KEGG PATHWAY (8)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (22)   
   KEGG ORTHOLOGY (1)   
   RefGene (16)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (11)   
   UniProt (1)   
   RefSeq(pep) (10)   
DNA sequence (10)   
   RefSeq(nuc) (10)   
Protein domain (7)   
   Pfam (7)   
All databases (64)   

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