KEGG   Canis lupus familiaris (dog): 478645
Entry
478645            CDS       T01007                                 
Symbol
MCCC1
Name
(RefSeq) methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial isoform X2
  KO
K01968  3-methylcrotonyl-CoA carboxylase alpha subunit [EC:6.4.1.4]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa00280  Valine, leucine and isoleucine degradation
cfa01100  Metabolic pathways
Module
cfa_M00036  Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    478645 (MCCC1)
Enzymes [BR:cfa01000]
 6. Ligases
  6.4  Forming carbon-carbon bonds
   6.4.1  Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
    6.4.1.4  methylcrotonoyl-CoA carboxylase
     478645 (MCCC1)
SSDB
Motif
Pfam: CPSase_L_D2 Biotin_carb_C Biotin_carb_N Biotin_lipoyl Dala_Dala_lig_C ATP-grasp Biotin_lipoyl_2 RimK ATP-grasp_3 ATPgrasp_ST PTS_EIIA_1 GARS_A ATP-grasp_4 RnfC_N HlyD_D23 NQRA ATPgrasp_Ter Orn_DAP_Arg_deC
Other DBs
NCBI-GeneID: 478645
NCBI-ProteinID: XP_038318687
Ensembl: ENSCAFG00000011749
VGNC: 43070
Position
34:complement(20111194..20173075)
AA seq 639 aa
MQQPQADEAYSIGPAPSQQSYLSMEKIIQVAKISAAQAIHPGYGFLSENMEFAELCKQEG
IIFVGPPSSAIKDMGIKSTSKSIMAAAGVPVVEGYHGEDQSDQCLREHAGKIGYPVMIKA
VRGGGGKGMRIVRSEEEFQEQLESARREAKKSFNDDAMLIEKFVDTPRHVEVQVFGDYHG
NAVYLFERDCSVQRRHQKIIEEAPGPGIKPDVRKKLGEAAVRAAKAVNYVGAGTVEFIMD
SKHNFYFMEMNTRLQVEHPVTEMITGTDLVEWQLRIAAGEKIPLSQEEITLQGHAFEARI
YAEDPANNFMPGAGPLVHLSTPQGDLCTRIETGVRQGDEVSVHYDPMIAKLVVWATDRQA
ALTKLRYSLRQYHIVGLHTNIDFLLSLSGHPEFEAGNVHTDFIAQHHKELFPSKKATAKE
FLCQAALGLIFKEKAVSDALKIQSQDQYSPFASSSGRRLNIFYTRNITLRDGKNNVAIAV
TYNHDGSYSMQIEDKTFQVLGDLCNEGDCTYLKCSVNGVASKTKLIILENTIYLFSMEGS
AQIDIPPPKYLSSMSSGGTQGGTIAPMTGTIEKVFVKVGDKVKAGDSLMVMIAMKMEHAI
KAPKDGTIKKVFYKEGSQANRHAPLIEFEEEESDKRKTE
NT seq 1920 nt   +upstreamnt  +downstreamnt
atgcaacaaccacaggcagatgaggcatattccattggcccagctccctcacagcagagc
tacctttcaatggagaaaatcattcaagtggccaagatctccgctgcccaggctatccat
ccaggatacggttttctttcagaaaacatggaatttgccgaactgtgtaaacaagaagga
attatttttgtaggtcctccttcatctgcaattaaagacatgggtataaagagcacatcc
aaatccattatggctgctgccggagtgcctgttgtggaaggttatcatggcgaggaccag
tcagatcagtgcctgagggagcacgcggggaaaatcggttatcctgtcatgattaaagcc
gtccgtggtggaggaggaaaagggatgaggatcgttagatctgaggaagaatttcaagag
cagttagaatcagcacggagagaagctaagaagtctttcaatgatgatgcgatgctgatt
gagaagtttgtggacacgccaaggcatgtagaagtccaggtgtttggtgactatcatggc
aacgctgtgtacttgtttgaaagagactgtagtgtacagaggagacatcagaagatcatt
gaggaagccccagggcctggcattaaacctgatgtaagaaagaagcttggagaagctgca
gtcagagctgctaaagctgtaaattatgttggagcaggaactgttgagtttattatggac
tcaaagcacaatttctacttcatggaaatgaatacaagactgcaagtggaacatcctgtt
actgagatgatcacaggaactgacttggtggagtggcagcttaggattgcagcaggagag
aagattcctttgagccaggaagaaataactctgcagggccatgcctttgaagctagaata
tatgcagaagatcctgccaataacttcatgccaggggctgggcccttggtgcatctctcc
acccctcagggagacctttgtactagaatcgaaactggagtgagacaaggagatgaagtt
tcagtgcattatgaccccatgattgcgaagctggttgtatgggctacagatcgccaggca
gccttgacgaaactgaggtacagccttcgtcagtaccatatcgtcggactgcacaccaat
attgacttcctcctcagcctgtctggccacccagagtttgaagcaggcaatgtgcacact
gatttcattgctcaacaccacaaagagctgtttcccagtaagaaggccacagccaaggag
tttttatgccaggcagctctgggtctcatcttcaaggagaaagctgtgtctgatgctctc
aaaattcagtcacaagatcagtactcaccttttgcatccagcagtggaagaagactgaat
atcttttacaccagaaacataaccctgagggatggtaaaaacaatgtagccatagctgta
acatataatcatgatgggtcatatagcatgcagattgaagacaaaactttccaagtcctt
ggtgatctttgtaatgagggagactgcacttacctgaaatgttctgttaatggagttgct
agtaaaactaagctaattatcctggaaaacactatttacctattttccatggaaggaagt
gctcagattgacattccaccccccaaatacttgtcttcgatgagctcaggtggaactcag
ggaggtaccatagctcctatgactggtaccattgaaaaggtatttgtgaaagttggagac
aaagtaaaagctggagattctctaatggttatgattgccatgaaaatggagcatgccata
aaggctccaaaggatggcacgatcaagaaagtgttctacaaagaaggttctcaggccaac
agacatgctcctttaatcgaatttgaggaagaggagtctgacaaaagaaaaacagaataa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (2)   
   KEGG MODULE (1)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   RefGene (11)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (16)   
   RefSeq(pep) (16)   
DNA sequence (16)   
   RefSeq(nuc) (16)   
Protein domain (18)   
   Pfam (18)   
All databases (81)   

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