KEGG   Canis familiaris (dog): 479351Help
Entry
479351            CDS       T01007                                 

Gene name
PRKAA1
Definition
protein kinase, AMP-activated, alpha 1 catalytic subunit
Orthology
K07198  
5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
Organism
cfa  Canis familiaris (dog)
Pathway
FoxO signaling pathway
Regulation of autophagy
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Circadian rhythm
Insulin signaling pathway
Adipocytokine signaling pathway
Oxytocin signaling pathway
Non-alcoholic fatty liver disease (NAFLD)
Hypertrophic cardiomyopathy (HCM)
Brite
KEGG Orthology (KO) [BR:cfa00001]
 Environmental Information Processing
  Signal transduction
   04068 FoxO signaling pathway
    479351 (PRKAA1)
   04151 PI3K-Akt signaling pathway
    479351 (PRKAA1)
   04152 AMPK signaling pathway
    479351 (PRKAA1)
   04150 mTOR signaling pathway
    479351 (PRKAA1)
 Cellular Processes
  Transport and catabolism
   04140 Regulation of autophagy
    479351 (PRKAA1)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    479351 (PRKAA1)
   04920 Adipocytokine signaling pathway
    479351 (PRKAA1)
   04921 Oxytocin signaling pathway
    479351 (PRKAA1)
  Environmental adaptation
   04710 Circadian rhythm
    479351 (PRKAA1)
 Human Diseases
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    479351 (PRKAA1)
  Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    479351 (PRKAA1)
Enzymes [BR:cfa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     479351 (PRKAA1)
Protein kinases [BR:cfa01001]
 Serine/threonine protein kinases: CAMK group
  CAMKL family
   479351 (PRKAA1)
Mitochondrial biogenesis [BR:cfa03029]
 Mitochondrial quality control factors
  Regulator of mitochondrial biogenesis
   Other regulator of mitochondrial biogenesis
    479351 (PRKAA1)
  Mitophagy factors
   Other mitophagy factors
    479351 (PRKAA1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
4
AA seq 587 aa AA seqDB search
MAPLAAPGVVRVSVPSRRFSPYLPGPILSVRWVPPPQPPPEMFLNYQFCRLCAKLVGKHE
LTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYV
SGGELFDYICKNGRKSDVPGVVRTGFMKELDEKESRRLFQQILSGVDYCHRHMVVHRDLK
PENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSG
VILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRATIKD
IREHEWFKQDLPKYLFPEDPSYSSTMIDDEALKEVCEKFECSEEEVLSCLYNRNHQDPLA
VAYHLIIDNRRIMNEAKDFYLATSPPDSFLDDHHLTRPHPERVPFLVAETPRARHTLDEL
NPQKSKHQGVRKAKWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVT
STYSKMSLQLYQVDSRTYLLDFRSIDDEITEAKSGTATPQRSGSVSNYRSCQRNDSDAEA
QGKSSEASLTSSVTSLDSSPVDLTPRPGSHTIEFFEMCANLIKILAQ
NT seq 1764 nt NT seq  +upstreamnt  +downstreamnt
atggcccccctggcggcgcccggggtcgtccgcgtttccgtcccctctaggaggttctcc
ccttacctgccggggccgattcttagtgtgcgatgggtgccccctcctcagcctccccca
gaaatgtttctgaattaccagttttgcagactctgtgccaaacttgttggcaaacatgaa
ttgactgggcataaagttgctgtgaagatactcaatcgacagaagattcgaagccttgat
gtggtaggaaaaatccgcagagaaattcagaacctcaagcttttcaggcatcctcatata
attaaactgtaccaggtcatcagtacaccatctgatattttcatggtgatggaatatgtc
tcaggaggagagctatttgattatatctgtaaaaatggaaggaaatctgatgtacctgga
gtagtaagaacaggcttcatgaaggagctggatgaaaaagaaagtcggcgtctgtttcaa
cagatcctttctggtgtggattactgtcacaggcatatggtggtccatagagatttgaaa
cctgaaaatgtcttgcttgatgcacacatgaatgcaaagatagctgattttggtctttca
aacatgatgtcagatggtgaatttttaagaacaagttgtggctcacccaactatgctgca
ccagaagtaatttcaggaagattgtatgcaggtccagaggtagatatatggagcagtggg
gttattctctatgctttattatgtggaacccttccatttgatgatgatcatgtgccaact
ctttttaagaagatatgtgatgggatcttttatacccctcagtatttaaatccatctgtg
attagccttttgaaacatatgctccaggtggatcccatgaagagggccacaatcaaagat
atcagggaacatgaatggtttaaacaagaccttccaaaatacctttttcccgaggatcca
tcgtatagttcaactatgattgatgatgaagccttaaaagaagtatgtgaaaaatttgag
tgctcagaagaggaagttctcagctgcctttataacagaaatcaccaggaccctttagca
gttgcctaccaccttataatagataacaggagaataatgaatgaggccaaagatttttac
ttggcaacaagcccacctgattcttttctcgatgatcaccatttgactcggccccatcct
gaaagagtaccattcttggttgctgaaacacctagggcacgccacactctcgatgaatta
aatccacagaaatctaagcaccaaggtgtaaggaaagcaaaatggcatttgggaattaga
agtcaaagtcgaccaaatgatatcatggcagaagtttgtagggcaattaaacaactggat
tatgaatggaaggttgtaaacccttattatttgcgtgttcgaaggaagaatcctgtgaca
agcacctactccaaaatgagtctacagttataccaagtggatagtagaacgtacttactg
gatttccgtagtatcgatgatgaaattactgaagccaaatcagggactgctactccacag
agatcgggatcagttagcaactatcgatcttgccaaaggaatgattcagatgctgaggct
caaggaaaatcctcagaagcttctcttacctcatctgtgacctcacttgactcttctcct
gttgatttaactccaagacctggaagtcacacaatagaattttttgagatgtgtgcaaat
ctaattaaaattcttgcacagtaa

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