KEGG   Canis lupus familiaris (dog): 480369
Entry
480369            CDS       T01007                                 
Symbol
ACTN1
Name
(RefSeq) alpha-actinin-1 isoform X2
  KO
K05699  actinin alpha 1/4
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa04510  Focal adhesion
cfa04520  Adherens junction
cfa04530  Tight junction
cfa04670  Leukocyte transendothelial migration
cfa04810  Regulation of actin cytoskeleton
cfa05146  Amoebiasis
cfa05203  Viral carcinogenesis
cfa05322  Systemic lupus erythematosus
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    480369 (ACTN1)
   04520 Adherens junction
    480369 (ACTN1)
   04530 Tight junction
    480369 (ACTN1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    480369 (ACTN1)
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    480369 (ACTN1)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    480369 (ACTN1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    480369 (ACTN1)
  09163 Immune disease
   05322 Systemic lupus erythematosus
    480369 (ACTN1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:cfa04131]
    480369 (ACTN1)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:cfa04812]
    480369 (ACTN1)
   04147 Exosome [BR:cfa04147]
    480369 (ACTN1)
Membrane trafficking [BR:cfa04131]
 Exocytosis
  Small GTPases and associated proteins
   Rab associated proteins
    480369 (ACTN1)
Cytoskeleton proteins [BR:cfa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Cross-linking proteins
     480369 (ACTN1)
Exosome [BR:cfa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   480369 (ACTN1)
  Exosomal proteins of colorectal cancer cells
   480369 (ACTN1)
  Exosomal proteins of bladder cancer cells
   480369 (ACTN1)
SSDB
Motif
Pfam: Spectrin CH EFhand_Ca_insen EF-hand_8 EF-hand_1 EF-hand_6 EF-hand_7 EF-hand_5 XisI Uds1
Other DBs
NCBI-GeneID: 480369
NCBI-ProteinID: XP_005623626
Ensembl: ENSCAFG00000016534
VGNC: 37548
Position
8:complement(42404474..42497710)
AA seq 894 aa
MEKVGDGERWGDKKETFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLAKP
ERGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDIS
VEETSAKEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPELIDYGKLRKDD
PLTNLNTAFDVAEKYLDIPKMLDAEDIVGTARPDEKAIMTYVSSFYHAFSGAQKAETAAN
RICKVLAVNQENEQLMEDYEKLASDLLEWIRRTIPWLENRAPENTMHAMQQKLEDFRDYR
RLHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGRMVSDINNAWGCLEQAEKGYEE
WLLNEIRRLERLDHLAEKFRQKASIHEAWTDGKEAMLRQKDYETATLSEIKALLKKHEAF
ESDLAAHQDRVEQIAAIAQELNELDYYDSPSVNARCQKICDQWDNLGALTQKRREALERT
EKLLETIDQLYLEYAKRAAPFNNWMEGAMEDLQDTFIVHTIEEIQGLTTAHEQFKATLPD
ADKERLAILGIHNEVSKIVQTYHVNMAGTNPYTTITPQEINGKWDHVRQLVPRRDQALTE
EHARQQHNERLRKQFAAQANVIGPWIQTKMEEIGRISIEMHGTLEDQLSHLRQYEKSIVN
YKPKIDQLEGDHQLIQEALIFDNKHTNYTMEHIRVGWEQLLTTIARTINEVENQILTRDA
KGISQEQMNEFRASFNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQKKTGMMDTDDFRA
CLISMGYNMGEAEFARIMSIVDPNRLGVVTFQAFIDFMSRETADTDTADQVMASFKILAG
DKNYITVDELRRELPPDQAEYCIARMAPYSGPDAVPGALDYMSFSTALYGESDL
NT seq 2685 nt   +upstreamnt  +downstreamnt
atggaaaaggtgggggatggagagaggtggggtgacaagaaggagacgttcacggcatgg
tgcaactcccacctccgcaaggcgggcacgcagatcgagaacatcgaggaggacttccgg
gatggactgaagctcatgctgctgctggaggtcatctcaggggagcgcttggccaagccg
gagagaggcaaaatgagagtgcacaagatctccaacgtcaacaaggccctggatttcata
gccagcaagggtgtcaagcttgtgtccattggagctgaagaaatcgtggatgggaatgtg
aaaatgactctgggcatgatctggaccatcatcctccgctttgccatccaggacatctct
gtggaagagacttctgcgaaggaagggctgctcttgtggtgtcaaagaaagacagcccct
tacaaaaatgtcaacatccagaatttccacataagctggaaggacggcctcggtttctgc
gccttgatccatcgacaccggcctgagctgattgactacgggaagctgcggaaggacgac
ccactcacaaatctgaacacagcctttgatgtggcagagaagtacctggacatccccaag
atgttggatgctgaagatatcgtcggaaccgcccgaccggatgagaaagccatcatgact
tacgtgtccagcttctaccatgccttctctggagcccagaaggcggagacagcagccaat
cgcatctgcaaggtgctggccgtcaaccaggagaacgagcagctcatggaagactatgag
aagctggccagcgatctgttggagtggatccgccgcaccatcccgtggctggagaaccgg
gcgccagagaacaccatgcatgccatgcagcagaagctggaggacttccgggactaccgg
cgcctgcacaagccgcccaaggtgcaggagaagtgccagctggagatcaacttcaacacg
ctgcagaccaagctgcgcctcagcaacaggcccgccttcatgccctcagagggcaggatg
gtctcggacatcaacaatgcctggggctgtctagagcaggctgagaaaggctacgaggag
tggctgctgaatgaaatccggaggctggagcggctcgaccacctggcagagaagttccgg
cagaaggcttccatccacgaggcctggacggacggcaaagaggctatgctacggcagaag
gattatgagactgccactctctcggagatcaaggccctgctcaagaagcacgaggccttt
gagagtgacctggctgcccaccaggaccgtgtggagcagattgccgccatcgcacaggag
ctcaatgagctggactattacgactcacccagtgtcaatgcccggtgccaaaagatttgt
gaccagtgggacaatctgggagcgctaacccagaagcggagggaagctctggagcggaca
gagaaattgctggagaccattgaccagctgtacttggagtatgccaagcgggctgcacct
ttcaacaactggatggagggggccatggaagatctacaggacaccttcatcgtgcacacc
attgaggagatccagggactgaccacagcccatgagcagttcaaggccaccctccctgat
gccgacaaggagcgcctggccatcctaggtatccacaacgaggtgtccaagattgtccag
acctaccacgtcaacatggcaggcaccaacccctacacaaccatcactcctcaggagatc
aatggcaaatgggaccacgtgcggcagttggtgccacggagggaccaggccctgacggag
gagcacgctcgccaacagcacaatgagaggctacgtaagcagtttgcagcccaggccaat
gtcatcgggccctggattcagaccaagatggaggagatagggcggatctccattgagatg
cacgggacgctggaggaccagctcagccacctgcgacagtacgagaagagcatcgtcaac
tataagcccaagatcgaccagctcgagggtgaccaccagctcatccaggaggcactcatc
tttgacaacaagcacaccaactacaccatggagcacatccgtgtgggctgggagcagctc
ctcaccaccatcgccaggaccatcaacgaagtggagaatcagatcctgacccgagatgcc
aagggcatcagccaggagcaaatgaatgaatttcgggcctccttcaaccactttgaccgg
gatcactccggcacgctgggtcccgaggagttcaaagcctgcctcatcagcttgggttat
gatattggcaacgacccccagaagaagacaggcatgatggacacggatgatttccgcgcc
tgccttatctccatgggttacaacatgggagaggcagaatttgcccgcatcatgagcatc
gtggatcccaaccgcctgggggtagtgacgttccaggccttcatcgactttatgtctcgg
gagacagccgacacagacacagccgaccaagtcatggcctccttcaagatcctggctggg
gacaagaactacatcaccgtggacgagctgcgccgagagctgccccccgaccaggccgag
tactgcatcgcgcggatggccccctactcgggccccgacgccgtgccgggtgctctggac
tacatgtccttctccacggcgctgtacggcgagagcgacctctaa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (8)   
   KEGG PATHWAY (8)   
Genome (1)   
   KEGG GENOME (1)   
Gene (37)   
   KEGG ORTHOLOGY (1)   
   RefGene (31)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (24)   
   RefSeq(pep) (24)   
DNA sequence (24)   
   RefSeq(nuc) (24)   
Protein domain (10)   
   Pfam (10)   
All databases (108)   

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