KEGG   Canis familiaris (dog): 483042Help
Entry
483042            CDS       T01007                                 

Gene name
SOS1
Definition
son of sevenless homolog 1 (Drosophila)
Orthology
K03099  
son of sevenless
Organism
cfa  Canis familiaris (dog)
Pathway
MAPK signaling pathway
ErbB signaling pathway
Ras signaling pathway
Chemokine signaling pathway
FoxO signaling pathway
PI3K-Akt signaling pathway
Dorso-ventral axis formation
Focal adhesion
Gap junction
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Neurotrophin signaling pathway
Regulation of actin cytoskeleton
Insulin signaling pathway
GnRH signaling pathway
Estrogen signaling pathway
Prolactin signaling pathway
Alcoholism
Hepatitis C
Pathways in cancer
Proteoglycans in cancer
MicroRNAs in cancer
Renal cell carcinoma
Endometrial cancer
Glioma
Prostate cancer
Chronic myeloid leukemia
Acute myeloid leukemia
Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:cfa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    483042 (SOS1)
   04010 MAPK signaling pathway
    483042 (SOS1)
   04012 ErbB signaling pathway
    483042 (SOS1)
   04630 Jak-STAT signaling pathway
    483042 (SOS1)
   04068 FoxO signaling pathway
    483042 (SOS1)
   04151 PI3K-Akt signaling pathway
    483042 (SOS1)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    483042 (SOS1)
  Cell communication
   04510 Focal adhesion
    483042 (SOS1)
   04540 Gap junction
    483042 (SOS1)
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    483042 (SOS1)
   04660 T cell receptor signaling pathway
    483042 (SOS1)
   04662 B cell receptor signaling pathway
    483042 (SOS1)
   04664 Fc epsilon RI signaling pathway
    483042 (SOS1)
   04062 Chemokine signaling pathway
    483042 (SOS1)
  Endocrine system
   04910 Insulin signaling pathway
    483042 (SOS1)
   04912 GnRH signaling pathway
    483042 (SOS1)
   04915 Estrogen signaling pathway
    483042 (SOS1)
   04917 Prolactin signaling pathway
    483042 (SOS1)
  Nervous system
   04722 Neurotrophin signaling pathway
    483042 (SOS1)
  Development
   04320 Dorso-ventral axis formation
    483042 (SOS1)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    483042 (SOS1)
   05206 MicroRNAs in cancer
    483042 (SOS1)
   05205 Proteoglycans in cancer
    483042 (SOS1)
   05214 Glioma
    483042 (SOS1)
   05221 Acute myeloid leukemia
    483042 (SOS1)
   05220 Chronic myeloid leukemia
    483042 (SOS1)
   05211 Renal cell carcinoma
    483042 (SOS1)
   05215 Prostate cancer
    483042 (SOS1)
   05213 Endometrial cancer
    483042 (SOS1)
   05223 Non-small cell lung cancer
    483042 (SOS1)
  Substance dependence
   05034 Alcoholism
    483042 (SOS1)
  Infectious diseases
   05160 Hepatitis C
    483042 (SOS1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
17
AA seq 1414 aa AA seqDB search
MGLKQPSRPHPTPAWKGALRWGTGRPGLSPCPLTWFIKREAPPHPHLSFSLLTSSPIISV
VRVGNIYRVLDGDLLSLLLYRLILKAQRPQAVRRGLCVGHRENLDVTWNEVQGQVHPTLE
SSDDALQYVEELILQLLNMLCQAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKR
RNPLSLPVEKIHPLLKEVLGYKIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITK
QDIKVAMCADKVLMDMFHQDVEDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIREL
NLIIKVFREPFVSNSKLFSANDVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLV
GSCFEDLAEELAFDPYESYARDILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVL
PRLLLAPVYHCLHYFELLKQLEEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRR
LSESACRFYSQQMKGKQLAIKKMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHER
HIFLFDGLMICCKSNHGQPRLPGASNAEYRLKEKFFMRKVQINDKDDTSEYKHAFEIILK
DENSVIFSAKSAEEKNNWMAALISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAE
PDSEENIIFEENMQPKAGIPIIKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQE
LLSLIIERFEIPEPEPTEADRIAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEH
HFYDFERDADLLQRMEEFIGTVRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPP
TVEWHISRPGHIETFDLLTLHPIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSP
NLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMN
SSPVYRLDHTFEQIPSRQKKILEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILK
TEEGNPEVLKRHGKELINFSKRRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGN
SMEKEFTDYLFNKSLEIEPRNPKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQE
PRKISYSRIPESETESTASAPNSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSSDT
VFIQVSLPHGPRSASVSSISLTKGTDEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSP
PAIPPRQPTSKAYSPRYSISDRTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLG
KKSDHGNAFFPNSPSPFTPPPPQTPSPHGTRRHLPSPPLTQEADLPSVTGPPVPPRQSTS
QHIPKLPPKTYKREHTHPSVHRDGPPLLENAHSS
NT seq 4245 nt NT seq  +upstreamnt  +downstreamnt
atgggcctgaaacagccaagccggcctcaccccacacctgcctggaagggggcgctgaga
tggggcaccgggcggcctggcctgtctccatgtcccctgacttggttcataaagcgggag
gcaccaccgcaccctcacctctccttctccctgctaacttccagccccataatctctgtc
gtcagggttggtaacatttacagggttctggacggagatttgctctccctgcttctctac
agactgattctaaaagctcaaagaccacaggcggtcaggagaggcctttgtgtgggccac
cgtgagaacttggatgtgacttggaacgaggtccagggacaagttcatccgactcttgag
tctagtgacgatgctcttcaatatgttgaagaattaattttgcagttattaaatatgcta
tgccaagctcagccccgaagtgcttcagatgtagaggaacgtgttcaaaaaagtttccct
catccaattgataagtgggcaatagctgatgcccaatcggctattgaaaagaggaagcga
agaaaccctttatctctcccagtagaaaaaattcatcctttattaaaggaggtcctaggt
tataaaattgaccaccaagtttctgtttacatagtagcagtattagaatacatttctgca
gacattttaaagctggtggggaattatgtacggaatatacggcattatgaaattacaaaa
caagatattaaagtggcaatgtgtgctgataaggtattaatggacatgtttcatcaagat
gtagaagatataaatatattatctttgactgatgaagagccttccacctcaggagagcaa
acttattatgatttggtaaaagcatttatggcagaaattcgacagtacataagggaacta
aatttaattataaaagtttttagagagccctttgtctccaattcaaaattgttttcagct
aatgatgtagaaaatatatttagtcgtatagtagatatacatgaacttagtgtaaagtta
ctgggccatatagaagatactgtggaaatgactgatgaagggagcccccatcccttagta
ggaagctgctttgaagacttagcagaggaactggcatttgatccatatgaatcatatgct
cgagatattttacggcctggttttcatgatcgtttccttagtcagttatcaaagcctgga
gcagcactctatttacagtcaataggcgaaggtttcaaagaagctgttcagtatgtttta
cccaggctacttctagcccctgtttaccactgtctacattactttgaacttttgaagcag
ttagaagaaaagagtgaagatcaagaggacaaggagtgtttgaaacaagcaataacagct
ttgcttaatgttcagagtggtatggaaaaaatatgttctaaaagtcttgcaaaacgaaga
ctgagtgaatctgcatgtcggttttatagtcagcaaatgaaggggaaacaactagcaatc
aagaaaatgaacgagattcaaaagaatattgatggttgggagggaaaagacattggacaa
tgttgcaatgaatttataatggaaggaactcttacacgtgtaggagccaaacatgagaga
cacatatttctctttgatggcttaatgatttgctgtaaatcaaatcatgggcagccaaga
cttcctggtgctagcaatgcagaatatcgtcttaaagaaaagtttttcatgagaaaggta
caaattaatgacaaagatgacaccagtgagtacaagcatgcttttgaaataattttaaaa
gatgaaaatagtgttatattttctgccaagtcagctgaagagaaaaacaattggatggca
gcattgatatctttacagtaccggagtacactggaaaggatgcttgatgtgacgatgcta
caggaagagaaggaggagcagatgaggctccctagtgccgatgtttatagatttgcagag
cctgactctgaagagaatataatatttgaagaaaacatgcagcccaaggctggaattcca
attatcaaagcaggaactgttattaaacttatagagaggctcacgtaccatatgtacgca
gatcccaattttgttcggacatttcttacaacatacagatccttttgtaaacctcaagaa
ctactgagtcttataatagaaaggtttgaaattccagagcctgagccaacagaagctgat
cgcatagctatagagaatggagatcagcccttgagtgcagaactaaaaaggtttagaaaa
gaatacatacagcctgtacaactgcgagtattaaatgtatgtcggcattgggtggagcac
cacttctatgattttgaaagagatgcagatcttttgcagcgaatggaagaatttattgga
acagtgagaggtaaagcaatgaaaaaatgggttgaatccatcactaaaataatccaaagg
aaaaaaattgcaagagacaatggaccaggtcataatattacatttcagagttcacctccc
acagtcgagtggcatataagcaggcctgggcacatagagacttttgacctgctcacctta
cacccaatagaaattgctcgacaactcactttacttgaatcagatctgtatcgagctgta
cagccatcagaattagttggaagtgtgtggacaaaagaagacaaagaaattaattctccc
aatcttctaaaaatgatccggcacaccactaatctcactctgtggtttgagaaatgtatt
gtagaaactgaaaacttagaagaaagagtagctgtggtgagtcgaataattgagattcta
caagtctttcaagagctgaacaacttcaatggtgttcttgaggttgtcagtgctatgaac
tcatcacctgtttacagactagaccacacatttgagcaaataccaagtcgccaaaagaaa
attttagaagaagctcatgaattaagtgaagatcactataagaaatatttggcaaaactc
aggtctattaatccaccatgtgtgcctttctttggaatttatctaactaatatcttgaaa
acagaagaaggcaaccctgaggtcctaaaaaggcatggaaaagagcttataaactttagc
aaaaggaggaaagtagcagaaataacaggagagatccagcagtaccaaaatcagccttat
tgtttacgagtagaatcagatatcaaaaggttttttgaaaatttgaatccaatgggaaat
agcatggaaaaagaatttacagattatcttttcaacaaatccctagagatagaaccacga
aaccctaagcctctgccaagatttccaaaaaaatatagctatcccctaaaatctcctggt
gttcgtccatcaaacccaagaccaggtaccatgagacatcctacacctctgcagcaggag
ccaaggaaaattagttatagtagaatccctgaaagtgaaacagaaagtacagcatctgca
ccaaattctccaagaacaccgttaacacctcctcctgcttctggtgcttctagtaccaca
gatgtttgcagcgtttttgattccgaccattcgagcccttttcactcaagcagcgatacc
gtctttatccaagtttcactgccccatggcccaagatctgcttcagtatcatctataagt
ttaaccaagggcactgatgaagtacctgtcccccctcctgttcctccacgaagaaggccg
gaatctgcccccgccgaatcttcaccgtctaagattatgtctaagcatttggacagcccc
ccagcaattcctcctaggcagcccacatcaaaagcctattcaccgcgatattcaatatca
gaccggacctctatatcagaccctcctgagagccctcccttattaccaccacgagaacct
gtgaggacacctgatgttttctccagctcaccactacatctccagcctccccctctgggc
aaaaaaagtgatcatggcaatgccttcttcccaaacagcccttccccttttacaccacct
cctcctcaaacaccttctccccatggcacgagaaggcatctgccatcaccaccattgaca
caagaagcggaccttccttcagtcactgggccgcctgttcctccacgacaaagcacttcc
caacatatccctaaactccctccgaaaacttataaaagggagcacacacacccatctgtg
cacagagatggaccacccctgttggagaatgcccattcttcctga

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