KEGG   Canis familiaris (dog): 483266Help
Entry
483266            CDS       T01007                                 

Gene name
PIK3CG
Definition
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
Orthology
K00922  
phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
Organism
cfa  Canis familiaris (dog)
Pathway
Inositol phosphate metabolism
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phosphatidylinositol signaling system
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Apoptosis
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Osteoclast differentiation
Focal adhesion
Signaling pathways regulating pluripotency of stem cells
Platelet activation
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Cholinergic synapse
Inflammatory mediator regulation of TRP channels
Regulation of actin cytoskeleton
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Prolactin signaling pathway
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Type II diabetes mellitus
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Carbohydrate digestion and absorption
Bacterial invasion of epithelial cells
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Amoebiasis
Hepatitis C
Hepatitis B
Measles
Influenza A
HTLV-I infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Colorectal cancer
Renal cell carcinoma
Pancreatic cancer
Endometrial cancer
Glioma
Prostate cancer
Melanoma
Chronic myeloid leukemia
Acute myeloid leukemia
Small cell lung cancer
Non-small cell lung cancer
Central carbon metabolism in cancer
Choline metabolism in cancer
Module
PI3K-Akt signaling
Brite
KEGG Orthology (KO) [BR:cfa00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    483266 (PIK3CG)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    483266 (PIK3CG)
   04015 Rap1 signaling pathway
    483266 (PIK3CG)
   04012 ErbB signaling pathway
    483266 (PIK3CG)
   04370 VEGF signaling pathway
    483266 (PIK3CG)
   04630 Jak-STAT signaling pathway
    483266 (PIK3CG)
   04668 TNF signaling pathway
    483266 (PIK3CG)
   04066 HIF-1 signaling pathway
    483266 (PIK3CG)
   04068 FoxO signaling pathway
    483266 (PIK3CG)
   04070 Phosphatidylinositol signaling system
    483266 (PIK3CG)
   04024 cAMP signaling pathway
    483266 (PIK3CG)
   04022 cGMP - PKG signaling pathway
    483266 (PIK3CG)
   04151 PI3K-Akt signaling pathway
    483266 (PIK3CG)
   04152 AMPK signaling pathway
    483266 (PIK3CG)
   04150 mTOR signaling pathway
    483266 (PIK3CG)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    483266 (PIK3CG)
  Cell growth and death
   04210 Apoptosis
    483266 (PIK3CG)
  Cellular commiunity
   04510 Focal adhesion
    483266 (PIK3CG)
   04550 Signaling pathways regulating pluripotency of stem cells
    483266 (PIK3CG)
 Organismal Systems
  Immune system
   04611 Platelet activation
    483266 (PIK3CG)
   04620 Toll-like receptor signaling pathway
    483266 (PIK3CG)
   04650 Natural killer cell mediated cytotoxicity
    483266 (PIK3CG)
   04660 T cell receptor signaling pathway
    483266 (PIK3CG)
   04662 B cell receptor signaling pathway
    483266 (PIK3CG)
   04664 Fc epsilon RI signaling pathway
    483266 (PIK3CG)
   04666 Fc gamma R-mediated phagocytosis
    483266 (PIK3CG)
   04670 Leukocyte transendothelial migration
    483266 (PIK3CG)
   04062 Chemokine signaling pathway
    483266 (PIK3CG)
  Endocrine system
   04910 Insulin signaling pathway
    483266 (PIK3CG)
   04915 Estrogen signaling pathway
    483266 (PIK3CG)
   04914 Progesterone-mediated oocyte maturation
    483266 (PIK3CG)
   04917 Prolactin signaling pathway
    483266 (PIK3CG)
   04921 Oxytocin signaling pathway
    483266 (PIK3CG)
   04919 Thyroid hormone signaling pathway
    483266 (PIK3CG)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    483266 (PIK3CG)
  Digestive system
   04973 Carbohydrate digestion and absorption
    483266 (PIK3CG)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    483266 (PIK3CG)
  Nervous system
   04725 Cholinergic synapse
    483266 (PIK3CG)
   04722 Neurotrophin signaling pathway
    483266 (PIK3CG)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    483266 (PIK3CG)
  Development
   04380 Osteoclast differentiation
    483266 (PIK3CG)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    483266 (PIK3CG)
   05230 Central carbon metabolism in cancer
    483266 (PIK3CG)
   05231 Choline metabolism in cancer
    483266 (PIK3CG)
   05205 Proteoglycans in cancer
    483266 (PIK3CG)
   05203 Viral carcinogenesis
    483266 (PIK3CG)
   05210 Colorectal cancer
    483266 (PIK3CG)
   05212 Pancreatic cancer
    483266 (PIK3CG)
   05214 Glioma
    483266 (PIK3CG)
   05221 Acute myeloid leukemia
    483266 (PIK3CG)
   05220 Chronic myeloid leukemia
    483266 (PIK3CG)
   05218 Melanoma
    483266 (PIK3CG)
   05211 Renal cell carcinoma
    483266 (PIK3CG)
   05215 Prostate cancer
    483266 (PIK3CG)
   05213 Endometrial cancer
    483266 (PIK3CG)
   05222 Small cell lung cancer
    483266 (PIK3CG)
   05223 Non-small cell lung cancer
    483266 (PIK3CG)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    483266 (PIK3CG)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    483266 (PIK3CG)
  Infectious diseases
   05100 Bacterial invasion of epithelial cells
    483266 (PIK3CG)
   05166 HTLV-I infection
    483266 (PIK3CG)
   05162 Measles
    483266 (PIK3CG)
   05164 Influenza A
    483266 (PIK3CG)
   05161 Hepatitis B
    483266 (PIK3CG)
   05160 Hepatitis C
    483266 (PIK3CG)
   05169 Epstein-Barr virus infection
    483266 (PIK3CG)
   05146 Amoebiasis
    483266 (PIK3CG)
   05145 Toxoplasmosis
    483266 (PIK3CG)
   05142 Chagas disease (American trypanosomiasis)
    483266 (PIK3CG)
Enzymes [BR:cfa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     483266 (PIK3CG)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
18
AA seq 1104 aa AA seqDB search
MEPQGREPRVVLREDHRRRRRRMKARGPAAGLPSMELIPIEFVLPTSQRSSKAPETALLH
VAGHGNVEQMKAQVWLRALETSAAADFYQRLGPDHFVLLYQKKGQWYEIYDRYQVVQTLD
CLRYWQLLHRSPGQIHVVQRRAPSAATLAFQRQLTALIGYDVTDLSNVHDNELEFTRRRL
VTPRMLEVAGRDPELYAMHPWVTSKPLPDYLRKRIPNNCVFIVIHRGTTSQTVKVSADDT
PGAILRSFFAKMAKKKALMGIPEGQSERDFVLRVCGRDEYLVGDTPLQNFQWVRQCLKNG
EEIHLVLDAPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRR
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKLFTEEVLWNVWLEFSIKI
KDLPRGALLNLQVYCSKAPTLSAKASADAPGAGSEARGKAQLLYYVNLLLIDHRFLLRRG
EYVLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDP
EGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKW
GQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLH
YLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVLLE
AYLRGCGTAMLHDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNLN
LPESFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDL
RQDMLILQILRIMESIWETESLDLYLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGN
TGAFKDEVLNHWLKEKCAIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETG
NLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYL
ALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEEAKKYFLDQIEVCRDK
GWTVQFNWFLHLVLGIKQGEKHSA
NT seq 3315 nt NT seq  +upstreamnt  +downstreamnt
atggagccgcagggccgtgagccgcgggtggtgctgagggaggaccaccgccgccggcgc
cggaggatgaaggcgcgcggcccggcggccggcctgccgtccatggagctcatccccatc
gagttcgtgctgcccaccagccagcgcagcagcaaggcccccgagacggcgctgctgcac
gtggcgggccacggcaacgtggagcagatgaaggcgcaggtgtggctgcgcgcgctggag
acgagcgcggcggccgacttctaccagcgcctcgggcccgaccacttcgtgctgctctac
cagaagaagggccagtggtacgagatctacgaccggtaccaggtggtgcagacgctcgac
tgcctgcgctactggcagctgctgcaccggagccccggccagatccacgtggtgcagcgg
cgcgcgccctcggccgccacgctcgccttccagcggcagctcacggcgctcatcggctac
gacgtcaccgacctcagcaacgtgcacgacaacgagctcgagttcacgcgccgccgcctg
gtcacgccgcgcatgctggaggtggccggccgcgaccccgagctctacgccatgcacccg
tgggtgacgtccaagcccctgcccgactacctgcggaagaggatccccaacaactgcgtc
ttcatcgtcatccaccgcggcaccaccagccagacggtcaaggtgtcggccgacgacacc
ccgggcgccatcctccggagcttcttcgccaagatggccaagaagaaggccctgatgggc
atccccgagggccagagcgagcgggacttcgtgctgcgcgtgtgcggccgcgacgagtac
ctggtgggggacacgcccctccagaacttccagtgggtgaggcagtgcctcaagaacgga
gaggagatccacctggtgctcgacgcgcctccggacccggccctggacgaggtgaggaag
gaggagtggccgctcgtggatgactgcacgggggtcaccggctaccacgagcagctcacc
atccacggcaaggaccacgagagcgtgttcaccgtgtccctgtgggactgcgaccgcagg
ttcagggtcaaaatccgaggcatcgacatccccgtgctgccccgcaacgccgacctcacc
gtcttcgtggaggccaacatccagcacgggcagcaggtcctctgccagaggagaaccagc
cccaagctcttcacggaggaggtgctctggaacgtgtggctggagttcagcatcaagatc
aaggacctgccgcgaggggccctcctgaacctgcaggtctactgcagcaaggcccccacg
ctgtccgccaaggcctcggccgacgcgcccggcgccgggtccgaggccaggggcaaagcc
cagctcctctactacgtgaacctgctgctgatagaccaccgcttcctgctgcgccgcggg
gagtacgtgctccacatgtggcagatctccggaaagggcgaggaccagggcagcttcaac
gccgacaagctcacgtcggccaccaaccccgacaaggagaactccatgtccatctccatt
cttctggacaattactgtcaccccatagccttgcccaagcatcggcccacccctgacccc
gaaggggaccgggttcgagcagaaatgcccaaccagcttcgcaagcagctggaggcgatc
atagccacggatccccttaaccctctcacggccgaggacaaggaattgctctggcatttt
cgatacgaaagtctcaagcatccaaaggcctatcctaagctgtttagctccgtaaaatgg
ggacagcaagagatcgtggccaaaacataccagctgttggccagacgggaggtctgggac
caaagcgctttggacgtgggcttaaccatgcaactcctggactgcaacttttcggatgag
aacgtcagagccatcgcagttcagaaactggagagcttggaggacgatgatgtcctgcat
tacctgctgcagctggtccaggctgtgaaatttgaaccataccatgacagcgccctcgcc
agatttctgctgaagcgtggcttaagaaacaaaagaattggtcatttcttgttttggttc
ttgagaagcgagatagcccagtccaggcactatcagcagaggtttgccgtgcttctggaa
gcctatctaaggggctgcggcactgccatgctgcacgacttcactcaacaagttcaagtg
attgagatgctacagaaggtcaccattgatatcaaatcgctctctgctgaaaaatacgat
gtcagttcccaagttatttcacaacttaagcaaaagcttgagaacctgcagaatttgaat
ctcccagaaagctttcgagtgccgtatgatcctggactgaaggcaggagcactagtgatt
gaaaaatgtaaagtgatggcctccaagaaaaagcccctatggcttgagtttaaatgtgct
gaccctacagccctatcgaatgaaacgattgggatcatctttaaacacggggatgatctg
cgccaagacatgctgattttacagattctacgaatcatggaatccatttgggagacagaa
tctttggatctgtacctcctgccatatggttgcatttcaactggagacaaaatagggatg
attgagatcgtgaaagatgccacaacaattgccaaaattcagcaaagcacagtgggcaac
acaggtgcattcaaagatgaagtcctgaatcactggctcaaagaaaaatgtgctattgaa
gaaaagtttcaggcagctgtggagagatttgtttattcctgtgctggctactgtgtggct
accttcgtcctgggaataggtgacaggcacaatgacaatattatgatcacagagacagga
aatctatttcatattgactttggacacattcttgggaattacaaaagtttcctgggcatt
aataaagagagagtgccatttgtgctaaccccagacttcctgtttgtgatgggaacttca
ggaaagaagacaagcctacacttccagaaatttcaggacgtctgcgttaaggcttacctc
gcccttcgccaccacacaaacctactgatcatcctgttctccatgatgctgatgacggga
atgccccagttaacaagcaaagaagatatcgaatatattcgggatgctctaacagtgggg
aagaacgaagaggaagctaagaagtattttcttgatcagatcgaggtttgcagggacaaa
ggatggactgtgcagtttaactggttcctgcatctcgtcctgggcatcaaacaaggagag
aaacattctgcctag

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