KEGG   Canis familiaris (dog): 483266Help
Entry
483266            CDS       T01007                                 

Gene name
PIK3CG
Definition
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
Orthology
K00922  
phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
Organism
cfa  Canis familiaris (dog)
Pathway
Inositol phosphate metabolism
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Chemokine signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phosphatidylinositol signaling system
mTOR signaling pathway
PI3K-Akt signaling pathway
Apoptosis
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Osteoclast differentiation
Focal adhesion
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Cholinergic synapse
Inflammatory mediator regulation of TRP channels
Regulation of actin cytoskeleton
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Prolactin signaling pathway
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Type II diabetes mellitus
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Carbohydrate digestion and absorption
Bacterial invasion of epithelial cells
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Amoebiasis
Hepatitis C
Hepatitis B
Measles
Influenza A
HTLV-I infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Colorectal cancer
Renal cell carcinoma
Pancreatic cancer
Endometrial cancer
Glioma
Prostate cancer
Melanoma
Chronic myeloid leukemia
Acute myeloid leukemia
Small cell lung cancer
Non-small cell lung cancer
Class
Metabolism; Carbohydrate metabolism; Inositol phosphate metabolism [PATH:cfa00562]
Environmental Information Processing; Signal transduction; Ras signaling pathway [PATH:cfa04014]
Environmental Information Processing; Signal transduction; Rap1 signaling pathway [PATH:cfa04015]
Environmental Information Processing; Signal transduction; ErbB signaling pathway [PATH:cfa04012]
Environmental Information Processing; Signal transduction; VEGF signaling pathway [PATH:cfa04370]
Environmental Information Processing; Signal transduction; Jak-STAT signaling pathway [PATH:cfa04630]
Environmental Information Processing; Signal transduction; TNF signaling pathway [PATH:cfa04668]
Environmental Information Processing; Signal transduction; HIF-1 signaling pathway [PATH:cfa04066]
Environmental Information Processing; Signal transduction; FoxO signaling pathway [PATH:cfa04068]
Environmental Information Processing; Signal transduction; Phosphatidylinositol signaling system [PATH:cfa04070]
Environmental Information Processing; Signal transduction; PI3K-Akt signaling pathway [PATH:cfa04151]
Environmental Information Processing; Signal transduction; mTOR signaling pathway [PATH:cfa04150]
Cellular Processes; Cell motility; Regulation of actin cytoskeleton [PATH:cfa04810]
Cellular Processes; Cell growth and death; Apoptosis [PATH:cfa04210]
Cellular Processes; Cell communication; Focal adhesion [PATH:cfa04510]
Organismal Systems; Immune system; Toll-like receptor signaling pathway [PATH:cfa04620]
Organismal Systems; Immune system; Natural killer cell mediated cytotoxicity [PATH:cfa04650]
Organismal Systems; Immune system; T cell receptor signaling pathway [PATH:cfa04660]
Organismal Systems; Immune system; B cell receptor signaling pathway [PATH:cfa04662]
Organismal Systems; Immune system; Fc epsilon RI signaling pathway [PATH:cfa04664]
Organismal Systems; Immune system; Fc gamma R-mediated phagocytosis [PATH:cfa04666]
Organismal Systems; Immune system; Leukocyte transendothelial migration [PATH:cfa04670]
Organismal Systems; Immune system; Chemokine signaling pathway [PATH:cfa04062]
Organismal Systems; Endocrine system; Insulin signaling pathway [PATH:cfa04910]
Organismal Systems; Endocrine system; Estrogen signaling pathway [PATH:cfa04915]
Organismal Systems; Endocrine system; Progesterone-mediated oocyte maturation [PATH:cfa04914]
Organismal Systems; Endocrine system; Prolactin signaling pathway [PATH:cfa04917]
Organismal Systems; Endocrine system; Oxytocin signaling pathway [PATH:cfa04921]
Organismal Systems; Endocrine system; Thyroid hormone signaling pathway [PATH:cfa04919]
Organismal Systems; Circulatory system; Adrenergic signaling in cardiomyocytes [PATH:cfa04261]
Organismal Systems; Digestive system; Carbohydrate digestion and absorption [PATH:cfa04973]
Organismal Systems; Excretory system; Aldosterone-regulated sodium reabsorption [PATH:cfa04960]
Organismal Systems; Nervous system; Cholinergic synapse [PATH:cfa04725]
Organismal Systems; Nervous system; Neurotrophin signaling pathway [PATH:cfa04722]
Organismal Systems; Sensory system; Inflammatory mediator regulation of TRP channels [PATH:cfa04750]
Organismal Systems; Development; Osteoclast differentiation [PATH:cfa04380]
Human Diseases; Cancers; Pathways in cancer [PATH:cfa05200]
Human Diseases; Cancers; Proteoglycans in cancer [PATH:cfa05205]
Human Diseases; Cancers; Viral carcinogenesis [PATH:cfa05203]
Human Diseases; Cancers; Colorectal cancer [PATH:cfa05210]
Human Diseases; Cancers; Pancreatic cancer [PATH:cfa05212]
Human Diseases; Cancers; Glioma [PATH:cfa05214]
Human Diseases; Cancers; Acute myeloid leukemia [PATH:cfa05221]
Human Diseases; Cancers; Chronic myeloid leukemia [PATH:cfa05220]
Human Diseases; Cancers; Melanoma [PATH:cfa05218]
Human Diseases; Cancers; Renal cell carcinoma [PATH:cfa05211]
Human Diseases; Cancers; Prostate cancer [PATH:cfa05215]
Human Diseases; Cancers; Endometrial cancer [PATH:cfa05213]
Human Diseases; Cancers; Small cell lung cancer [PATH:cfa05222]
Human Diseases; Cancers; Non-small cell lung cancer [PATH:cfa05223]
Human Diseases; Endocrine and metabolic diseases; Type II diabetes mellitus [PATH:cfa04930]
Human Diseases; Endocrine and metabolic diseases; Non-alcoholic fatty liver disease (NAFLD) [PATH:cfa04932]
Human Diseases; Infectious diseases; Bacterial invasion of epithelial cells [PATH:cfa05100]
Human Diseases; Infectious diseases; HTLV-I infection [PATH:cfa05166]
Human Diseases; Infectious diseases; Measles [PATH:cfa05162]
Human Diseases; Infectious diseases; Influenza A [PATH:cfa05164]
Human Diseases; Infectious diseases; Hepatitis B [PATH:cfa05161]
Human Diseases; Infectious diseases; Hepatitis C [PATH:cfa05160]
Human Diseases; Infectious diseases; Epstein-Barr virus infection [PATH:cfa05169]
Human Diseases; Infectious diseases; Amoebiasis [PATH:cfa05146]
Human Diseases; Infectious diseases; Toxoplasmosis [PATH:cfa05145]
Human Diseases; Infectious diseases; Chagas disease (American trypanosomiasis) [PATH:cfa05142]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
UniProt: 
Position
18
AA seq 1104 aa AA seqDB search
MEPQGREPRVVLREDHRRRRRRMKARGPAAGLPSMELIPIEFVLPTSQRSSKAPETALLH
VAGHGNVEQMKAQVWLRALETSAAADFYQRLGPDHFVLLYQKKGQWYEIYDRYQVVQTLD
CLRYWQLLHRSPGQIHVVQRRAPSAATLAFQRQLTALIGYDVTDLSNVHDNELEFTRRRL
VTPRMLEVAGRDPELYAMHPWVTSKPLPDYLRKRIPNNCVFIVIHRGTTSQTVKVSADDT
PGAILRSFFAKMAKKKALMGIPEGQSERDFVLRVCGRDEYLVGDTPLQNFQWVRQCLKNG
EEIHLVLDAPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRR
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKLFTEEVLWNVWLEFSIKI
KDLPRGALLNLQVYCSKAPTLSAKASADAPGAGSEARGKAQLLYYVNLLLIDHRFLLRRG
EYVLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDP
EGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKW
GQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLH
YLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVLLE
AYLRGCGTAMLHDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNLN
LPESFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDL
RQDMLILQILRIMESIWETESLDLYLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGN
TGAFKDEVLNHWLKEKCAIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETG
NLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYL
ALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEEAKKYFLDQIEVCRDK
GWTVQFNWFLHLVLGIKQGEKHSA
NT seq 3315 nt NT seq  +upstreamnt  +downstreamnt
atggagccgcagggccgtgagccgcgggtggtgctgagggaggaccaccgccgccggcgc
cggaggatgaaggcgcgcggcccggcggccggcctgccgtccatggagctcatccccatc
gagttcgtgctgcccaccagccagcgcagcagcaaggcccccgagacggcgctgctgcac
gtggcgggccacggcaacgtggagcagatgaaggcgcaggtgtggctgcgcgcgctggag
acgagcgcggcggccgacttctaccagcgcctcgggcccgaccacttcgtgctgctctac
cagaagaagggccagtggtacgagatctacgaccggtaccaggtggtgcagacgctcgac
tgcctgcgctactggcagctgctgcaccggagccccggccagatccacgtggtgcagcgg
cgcgcgccctcggccgccacgctcgccttccagcggcagctcacggcgctcatcggctac
gacgtcaccgacctcagcaacgtgcacgacaacgagctcgagttcacgcgccgccgcctg
gtcacgccgcgcatgctggaggtggccggccgcgaccccgagctctacgccatgcacccg
tgggtgacgtccaagcccctgcccgactacctgcggaagaggatccccaacaactgcgtc
ttcatcgtcatccaccgcggcaccaccagccagacggtcaaggtgtcggccgacgacacc
ccgggcgccatcctccggagcttcttcgccaagatggccaagaagaaggccctgatgggc
atccccgagggccagagcgagcgggacttcgtgctgcgcgtgtgcggccgcgacgagtac
ctggtgggggacacgcccctccagaacttccagtgggtgaggcagtgcctcaagaacgga
gaggagatccacctggtgctcgacgcgcctccggacccggccctggacgaggtgaggaag
gaggagtggccgctcgtggatgactgcacgggggtcaccggctaccacgagcagctcacc
atccacggcaaggaccacgagagcgtgttcaccgtgtccctgtgggactgcgaccgcagg
ttcagggtcaaaatccgaggcatcgacatccccgtgctgccccgcaacgccgacctcacc
gtcttcgtggaggccaacatccagcacgggcagcaggtcctctgccagaggagaaccagc
cccaagctcttcacggaggaggtgctctggaacgtgtggctggagttcagcatcaagatc
aaggacctgccgcgaggggccctcctgaacctgcaggtctactgcagcaaggcccccacg
ctgtccgccaaggcctcggccgacgcgcccggcgccgggtccgaggccaggggcaaagcc
cagctcctctactacgtgaacctgctgctgatagaccaccgcttcctgctgcgccgcggg
gagtacgtgctccacatgtggcagatctccggaaagggcgaggaccagggcagcttcaac
gccgacaagctcacgtcggccaccaaccccgacaaggagaactccatgtccatctccatt
cttctggacaattactgtcaccccatagccttgcccaagcatcggcccacccctgacccc
gaaggggaccgggttcgagcagaaatgcccaaccagcttcgcaagcagctggaggcgatc
atagccacggatccccttaaccctctcacggccgaggacaaggaattgctctggcatttt
cgatacgaaagtctcaagcatccaaaggcctatcctaagctgtttagctccgtaaaatgg
ggacagcaagagatcgtggccaaaacataccagctgttggccagacgggaggtctgggac
caaagcgctttggacgtgggcttaaccatgcaactcctggactgcaacttttcggatgag
aacgtcagagccatcgcagttcagaaactggagagcttggaggacgatgatgtcctgcat
tacctgctgcagctggtccaggctgtgaaatttgaaccataccatgacagcgccctcgcc
agatttctgctgaagcgtggcttaagaaacaaaagaattggtcatttcttgttttggttc
ttgagaagcgagatagcccagtccaggcactatcagcagaggtttgccgtgcttctggaa
gcctatctaaggggctgcggcactgccatgctgcacgacttcactcaacaagttcaagtg
attgagatgctacagaaggtcaccattgatatcaaatcgctctctgctgaaaaatacgat
gtcagttcccaagttatttcacaacttaagcaaaagcttgagaacctgcagaatttgaat
ctcccagaaagctttcgagtgccgtatgatcctggactgaaggcaggagcactagtgatt
gaaaaatgtaaagtgatggcctccaagaaaaagcccctatggcttgagtttaaatgtgct
gaccctacagccctatcgaatgaaacgattgggatcatctttaaacacggggatgatctg
cgccaagacatgctgattttacagattctacgaatcatggaatccatttgggagacagaa
tctttggatctgtacctcctgccatatggttgcatttcaactggagacaaaatagggatg
attgagatcgtgaaagatgccacaacaattgccaaaattcagcaaagcacagtgggcaac
acaggtgcattcaaagatgaagtcctgaatcactggctcaaagaaaaatgtgctattgaa
gaaaagtttcaggcagctgtggagagatttgtttattcctgtgctggctactgtgtggct
accttcgtcctgggaataggtgacaggcacaatgacaatattatgatcacagagacagga
aatctatttcatattgactttggacacattcttgggaattacaaaagtttcctgggcatt
aataaagagagagtgccatttgtgctaaccccagacttcctgtttgtgatgggaacttca
ggaaagaagacaagcctacacttccagaaatttcaggacgtctgcgttaaggcttacctc
gcccttcgccaccacacaaacctactgatcatcctgttctccatgatgctgatgacggga
atgccccagttaacaagcaaagaagatatcgaatatattcgggatgctctaacagtgggg
aagaacgaagaggaagctaagaagtattttcttgatcagatcgaggtttgcagggacaaa
ggatggactgtgcagtttaactggttcctgcatctcgtcctgggcatcaaacaaggagag
aaacattctgcctag

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