KEGG   Canis familiaris (dog): 484196Help
Entry
484196            CDS       T01007                                 

Gene name
SYK
Definition
spleen tyrosine kinase
Orthology
K05855  
spleen tyrosine kinase [EC:2.7.10.2]
Organism
cfa  Canis familiaris (dog)
Pathway
NF-kappa B signaling pathway
PI3K-Akt signaling pathway
Osteoclast differentiation
Platelet activation
Natural killer cell mediated cytotoxicity
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
Tuberculosis
Epstein-Barr virus infection
Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:cfa00001]
 Environmental Information Processing
  Signal transduction
   04064 NF-kappa B signaling pathway
    484196 (SYK)
   04151 PI3K-Akt signaling pathway
    484196 (SYK)
 Organismal Systems
  Immune system
   04611 Platelet activation
    484196 (SYK)
   04650 Natural killer cell mediated cytotoxicity
    484196 (SYK)
   04662 B cell receptor signaling pathway
    484196 (SYK)
   04664 Fc epsilon RI signaling pathway
    484196 (SYK)
   04666 Fc gamma R-mediated phagocytosis
    484196 (SYK)
  Development
   04380 Osteoclast differentiation
    484196 (SYK)
 Human Diseases
  Cancers
   05203 Viral carcinogenesis
    484196 (SYK)
  Infectious diseases
   05152 Tuberculosis
    484196 (SYK)
   05169 Epstein-Barr virus infection
    484196 (SYK)
Enzymes [BR:cfa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     484196 (SYK)
Protein kinases [BR:cfa01001]
 Tyrosine protein kinases
  Syk family
   484196 (SYK)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
1
AA seq 633 aa AA seqDB search
MAGSTADSANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKA
HHYTIEREMNGTYAIAGGRTHGSPAELCHYHSQESDGLVCLLKQPFHRPPGVQPKTGPFE
DLKESLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISRVESEQI
VMIGSKTNGKFLIRDRNDNGSYALCLLHEGKVLHYRIDKDKTGKLSIPDGKKFDTLWQLV
EHYSYKPDGLLRVLTVPCQKIGGQPGNINFGARAPLPGAHPATWSAGGIISRIKSYTFPK
PGHRKAASSTGSRPESSFNPYEPDRGPWATDRDAQREALPMDTEVYESPYADPEEIRPKE
VYLDRKLLTLEDNELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEAN
VMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGM
KYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPE
CINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVSAMLEKGERMGCPAGCPREMY
ELMKLCWTYEVDRRPGFEAVELRLRNYYYDVVN
NT seq 1902 nt NT seq  +upstreamnt  +downstreamnt
atggcgggaagcacggccgacagcgccaaccacctgccgttcttcttcggcaacatcacc
cgggaggaagcggaggactacctggtccagggcggcatgagcgatgggctgtacctgctg
cgccagagccgcaactacctgggcggcttcgcgctgtcggtggcgcacgggaggaaggcg
caccactacaccatcgagcgcgagatgaacggcacctacgccatcgcgggcggcaggacg
cacggcagcccggccgagctgtgccactaccactcccaggagtccgacggcctcgtctgc
ctcctcaagcagcccttccaccggccgcccggggtgcagcccaagaccggcccgttcgag
gatctgaaggagagcctcatcagggagtacgtgaagcagacctggaacctgcagggtcag
gctctggagcaggccattatcagccagaaacctcagctggagaagctgatcgccaccacg
gcccacgaaaaaatgccctggttccacgggaagatctcacgagttgaatctgagcaaatt
gtcatgataggctccaagacaaatggaaaatttttgatcagggacagaaatgacaatggg
tcttatgccctgtgcctgctgcacgagggaaaggtgttgcactaccgcatcgataaggac
aaaacggggaagctgtccatccctgatgggaagaagttcgacacactctggcagctagtg
gagcattactcttataaaccagatgggcttctaagagttctcacagttccatgccagaaa
attggcgggcagccaggaaacatcaacttcggagcccgtgcgcccctccctggtgcccat
cctgcgacatggtcggcgggtggaataatctcaaggatcaaatcctacaccttcccaaag
cctggccacagaaaggctgcctcgtctacagggagccggccagaaagctccttcaatcct
tacgagccggaccgggggccctgggccacggacagagacgcccagagagaggccttgccc
atggacacagaagtgtatgaaagcccgtatgccgaccctgaggagatcaggcccaaggag
gtctacctggaccgcaaactgctgaccctggaggacaacgaactgggctctgggaacttc
gggactgtgaagaagggctattaccagatgaaaaaagtcgtgaaaacagtggctgtgaag
attctgaagaatgaggctaatgaccctgctcttaaagatgagttgttagcagaagcgaac
gtcatgcagcagcttgacaacccttacatcgtgcgcatgattgggatctgtgaagccgag
tcctggatgctggtcatggaaatggcagaactgggtccactcaataaatatttacagcag
aacaggcacgtcaaggataagaacattatagagctggttcatcaggtttctatgggaatg
aaatatctggaggagagcaattttgtgcacagagatctggctgcaagaaatgtattgctg
gttactcaacattatgccaagattagtgatttcggactttccaaagcactccgtgctgat
gaaaactactacaaggcccagacccacgggaagtggcccgtgaagtggtacgccccggag
tgcatcaactactacaagttctccagcaagagtgacgtctggagcttcggcgtgttgatg
tgggaggcgttctcctatgggcagaagccctatcggggcatgaaaggaagtgaagtttca
gctatgctggagaaaggagagaggatggggtgccccgcggggtgtccaagggagatgtac
gagctgatgaagctgtgctggacatatgaggtggatcgcaggccggggttcgaagccgtg
gagctgcggctgcgcaattattactacgacgtggtgaactaa

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