KEGG   Canis lupus familiaris (dog): 485402
Entry
485402            CDS       T01007                                 
Symbol
ABCC8
Name
(RefSeq) ATP-binding cassette sub-family C member 8 isoform X1
  KO
K05032  ATP-binding cassette subfamily C (CFTR/MRP) member 8
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa02010  ABC transporters
cfa04911  Insulin secretion
cfa04930  Type II diabetes mellitus
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09130 Environmental Information Processing
  09131 Membrane transport
   02010 ABC transporters
    485402 (ABCC8)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    485402 (ABCC8)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    485402 (ABCC8)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:cfa02000]
    485402 (ABCC8)
Transporters [BR:cfa02000]
 ABC transporters, eukaryotic type
  ABCC (CFTR/MRP) subfamily
   ABCC8, 9 subgroups
    485402 (ABCC8)
SSDB
Motif
Pfam: ABC_membrane ABC_tran SMC_N ABC_ATPase AAA_29 ATPase AAA_25 nSTAND1 AAA_23 RsgA_GTPase Zeta_toxin TraD_N
Other DBs
NCBI-GeneID: 485402
NCBI-ProteinID: XP_038312322
Ensembl: ENSCAFG00000008779
VGNC: 37443
Position
21:complement(39461452..39537172)
AA seq 1587 aa
MPLAFCGSENRSAAYRVDQGVLNNGCFVDALNVVPHVFLLFITFPILFIGWGSQSSKVHI
HHSTWLHFPGHNLRWILTFMLLFVLVCEIAEGILSDGVTESRHLHLYMPAGMAFMAAVTS
VVYYHNIETSNFPKLLIALLVYWTLAFITKTIKFVKFYDHSISFSQLRFCLTGLLVILYG
MLLLVEVNVIMVRRYIFFKSPREVKPPEDLQDLGVRFLQPFVNLLSKGTYWWMNAFIKTA
HKKPIDLRAIGKLPIAMRALTNYQRLCEAFDTQAQKDSQSTQGARAIWQALCHAFGRRLV
LSSTFRILADLLGFAGPLCIFGIVDHLGKENRVFQPKTQFLGVYFVSSQEFLANAYVLAV
LLFLALLLQRTFLQASYYVAIETGINLRGAIQTKIYNKIMHLSTSNLSMGEMTAAQICNL
VAIDTNQLMWFFFLCPNLWAMPVQIIVGVILLYYILGVSALIGAAVIILLAPVQYFVATK
LSQAQRSTLEYSNERLKQTNEMLRGIKLLKLYAWENIFCTRVEMTRRKEMTSLRAFAVYT
SISIFMNTAIPIAAVLITFVGHVSFFKEADFSPSVAFASLSLFHILVTPLFLLSSVVRST
VKALVSVQKLSEFLSSAEIREEQCAPREPAPQGQASKYQAVPLKVVNRKHPAREDCRGFS
APLQRLAPSADGDADSCCVQIIGGFFTWTPDGIPTLSNITIRIPRGQLTMIVGQVGCGKS
SLLLATLGEMQKISGAVFWNSSLPEETGEDPRYSLGTGPERETVADSDVRKRGPVAYASQ
KPWLLNATVEENITFESPFNKQRYKMVIEACSLQPDIDILPHGDQTQIGERGINLSGGQR
QRISVARALYQHTNVVFLDDPFSALDVHLSDHLMQAGILELLQDDKRTVVLVTHKLQYLP
HADWIIAMKDGTIQREGTLKDFQRSECQLFEHWKTLMNRQDQELEKETVVERKATEPPQG
LPRAMSSRDGLLQDEEEEEEEAAESEEEDNLSSVLHQRAKIPWRACAKYLSSAGILLLSL
LVFSQLLKHMVLVAIDYWLAKWTDSALTLSPAARNCSLSQECSLDQTVYAMVFTVLCSLG
IVLCLVTSVTVEWTGLKVAKSLHRSLLNRIILAPMRFFETTPLGSILNRFSADCNTIDQH
IPSTLECLSRSTLLCVSALAVISYVTPVFLVALLPLAVVCYFIQKYFRVASRDLQQLDDT
TQLPLLSHFAETVEGLTTIRAFRYEARFQQKLLEYTDSNNIASLFLTAANRWLEVRMEYI
GACVVLIAAVTSISNSLHRELSAGLVGLGLTYALMVSNYLNWMVRNLADMEIQLGAVKRI
HGLLKTEAESYEGLLAPSLIPKNWPDQGKIQIQNLSVRYDSSLKPVLKHVNALISPGQKI
GICGRTGSGKSSFSLAFFRMVDTFEGRIIIDGIDIAKLPLHTLRSRLSIILQDPVLFSGT
IRFNLDPEKKCSDSTLWEALEIAQLKLVVKALPGGLDAIITEGGENFSQGQRQLFCLARA
FVRKTSIFIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVHTILSADLVIVLKRG
AILEFDKPEKLLSRKDSVFASFVRADK
NT seq 4764 nt   +upstreamnt  +downstreamnt
atgcccttggccttctgcggcagcgagaaccgctcggccgcctaccgggtggaccagggc
gtcctcaacaacggctgcttcgtggacgcgctcaacgtggtgccgcacgtcttcctgctc
ttcatcaccttccccatcctcttcatcggatggggcagtcaaagctccaaggtacacatc
caccatagcacatggctccacttccctgggcacaacctgcgctggatcctgaccttcatg
ctgctctttgtcctggtgtgtgaaatcgcggagggcatcctgtccgatggggtgactgaa
tcccgccatctccacctgtacatgccagccgggatggcgttcatggctgctgtcacctcc
gtggtctactatcacaacatcgagacctccaacttccccaagctgctgatagccctgcta
gtctactggaccctggctttcatcaccaagaccatcaagttcgtcaagttctatgaccac
tccatcagcttctcacagctgcgcttctgcctcacggggctgctggtgattctctacggg
atgctgctcctggtggaggtcaatgtcatcatggtgaggagatatatcttcttcaagtca
ccaagggaagtgaagccccctgaggacctacaggacttgggggtgcgcttcctgcagccc
tttgtgaacctgctgtcgaaaggcacctactggtggatgaatgctttcatcaagactgct
cacaagaagcccattgatctccgagccattggcaagctacccattgccatgagggctctc
accaactaccagcggctctgtgaggccttcgacacccaagcgcagaaggactcgcagagc
acacagggggcccgggccatctggcaggcactttgccatgccttcgggagacgcctggtc
ctcagcagcactttccgcatcttggccgacctgctgggcttcgctgggccactgtgcatc
ttcgggattgtggaccaccttgggaaggagaaccgcgtcttccagcccaagacgcagttt
ctcggggtttactttgtctcgtcccaagagttccttgctaatgcctacgtcctagctgtg
cttctcttccttgccctcctactacaaaggacgtttctgcaagcatcttactacgttgcc
attgaaactggaattaacttgagaggagcaatacagaccaagatttacaacaaaatcatg
cacctgtccacctccaatctgtccatgggggaaatgacagccgcgcagatctgcaacctg
gttgccattgacaccaaccagctcatgtggtttttcttcttgtgcccaaacctctgggct
atgccagtgcagatcatcgtgggtgtgattctcctctactacatcctcggagtcagtgcc
ttaattggggcagctgtcatcatcctactggcccctgtccagtactttgtggccaccaag
ctctcccaggcccagcggagcacactggagtactccaacgagaggctgaagcagaccaac
gagatgcttcgaggcatcaagctgctcaagctgtacgcctgggaaaacatcttttgcacg
cgcgtggagatgacccgcaggaaggagatgaccagcctcagagcctttgctgtgtacact
tccatttccattttcatgaacacggccatccccatcgcagcagtgctgatcaccttcgtg
ggccacgtcagcttcttcaaagaggccgacttctcaccctcggtggcctttgcctccctc
tcgctcttccacatcctggtcacaccactgttcctgctgtccagcgtggtccgatctaca
gtcaaagctctagtcagcgtgcagaagctgagcgagttcctgtccagtgcagagatccgt
gaggagcagtgtgcgccccgcgagcctgcgccgcagggccaagccagcaagtaccaggca
gtgccccttaaggtcgtgaaccgcaagcatccagcccgggaggactgtcggggcttctcg
gccccgctgcagaggctggcccccagtgcagatggggatgctgacagctgctgtgtccag
atcattggaggcttcttcacatggacccctgatggaattcccacactgtccaacatcacc
atccgcatcccccgaggccagctgaccatgatcgtggggcaggtgggctgcggcaagtcc
tcgctcctcctagccaccctaggggagatgcagaagatctcaggggccgtcttctggaac
agcagccttcctgaggagacgggagaggaccccaggtacagcctcggaactggcccagag
cgggagacagtggctgattcggacgtcaggaagagaggccccgtggcctatgcttctcag
aaaccatggctgctaaatgccactgtggaggagaatatcacctttgagagtcccttcaac
aaacaacggtacaaaatggtcatcgaggcctgctccctgcagccggacatcgacatccta
ccccacggagaccagactcagatcggggaacggggcatcaacctatctggtggccaacgc
cagcgaatcagtgtggcccgagccctgtaccagcacaccaatgttgtcttcttggatgac
cccttctcagctctggatgtccatctgagtgaccacctgatgcaggctgggatccttgag
ctgctccaggacgacaaaaggacagtggtcctcgtgacccacaagctccagtacctgcca
catgcagactggatcatcgcgatgaaggatggcaccatccagagggagggcacgctcaag
gacttccagaggtctgagtgccagctctttgagcactggaagaccctcatgaatcggcag
gaccaagagctggagaaggagactgttgtggagagaaaagccacagagccacctcagggc
ctgccccgggccatgtcctcaagagacggcctcctgcaggatgaggaagaggaggaagag
gaggccgctgagagcgaggaggaggacaacctgtcctcggtgctgcaccagcgagccaag
atcccgtggcgagcctgtgccaagtatttgtcgtccgccggcatcctgctcctgtcgctg
ctcgtcttctcccagctgctcaagcacatggtcctggtggccattgactactggctggcc
aagtggaccgacagcgccctgaccctgagccccgcggccaggaactgctccctcagccag
gagtgctccctcgaccagactgtctacgccatggtgttcacggtgctgtgcagcctgggc
attgtgttgtgccttgtcacgtcggtcaccgtggagtggacagggctaaaggtggccaaa
agcttgcaccgcagcctgctgaaccggatcatcctggctcccatgaggttttttgagacc
acgccccttggaagcatcctgaatagattttcagctgactgtaacaccatcgaccagcac
atcccatccacgctggaatgcctgagccgctccaccctgctctgtgtctcagccctggct
gtcatctcctatgtcacgcctgtgttcctcgtggccctcttgcccctggccgtggtgtgc
tacttcatccagaagtatttccgggtggcatccagggacctgcagcagctggatgatacc
acccagctccctctgctctcccattttgctgaaactgtagaaggtctcaccaccatccgg
gccttcaggtatgaggctaggttccagcagaagctcctcgaatacacggactccaacaac
atcgcctccctgttcctcacggctgccaacagatggctagaagtccgcatggagtacatc
ggtgcctgcgtggtcctcatcgccgccgtgacctccatctccaactccctgcacagggag
ctctctgctggcctggtgggcctgggccttacctatgccctaatggtctccaactacctc
aactggatggtgaggaacctggcagacatggagatccagctgggggccgtgaagcgcatc
catgggctcctcaaaaccgaggcggagagttacgaggggctgctggcaccctcactcatc
ccgaagaactggccagaccaagggaagatccagatccagaacctcagtgtgcgctatgac
agctccctgaagccagtgctgaagcatgtcaacgccctcatctccccaggacagaagatt
gggatctgcggccgcacaggcagtgggaagtcttccttctctctcgccttcttccgcatg
gtggacacgtttgaggggcgcatcatcattgacggcatcgacatcgccaaactgccactg
cataccctgcgctcccgcctctctatcatcctgcaggaccccgtcctcttcagcggcacc
atccggtttaacctggacccggagaagaagtgctcggacagcacgctgtgggaggccctg
gagatcgcccagctgaagctggtggtgaaggcgctgcctggaggcctggatgccatcatc
acggaaggtggggagaatttcagccaaggccagaggcaactgttctgcctggctcgggcc
ttcgtgaggaagaccagcatcttcatcatggatgaagccacggcctccatcgacatggcc
acggaaaacatcctccagaaggtggtaatgacggccttcgcagaccgcactgtggtcacc
atcgcgcaccgtgtgcacaccatcctgagtgcggacctggtgattgtcctgaagcgcggc
gccatccttgagttcgacaagccagagaagctgctcagccggaaggacagcgtcttcgcc
tccttcgtgcgtgcagacaagtga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (20)   
   KEGG ORTHOLOGY (1)   
   RefGene (14)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (35)   
   RefSeq(pep) (35)   
DNA sequence (37)   
   RefSeq(nuc) (35)   
   GenBank (1)   
   EMBL (1)   
Protein domain (12)   
   Pfam (12)   
All databases (110)   

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