KEGG   Canis familiaris (dog): 485773Help
Entry
485773            CDS       T01007                                 

Gene name
PLCB1
Definition
phospholipase C, beta 1 (phosphoinositide-specific)
Orthology
K05858  
phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
cfa  Canis familiaris (dog)
Pathway
Inositol phosphate metabolism
Metabolic pathways
Rap1 signaling pathway
Calcium signaling pathway
Chemokine signaling pathway
Phosphatidylinositol signaling system
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Wnt signaling pathway
Gap junction
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
Dopaminergic synapse
Long-term depression
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Endocrine and other factor-regulated calcium reabsorption
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Alzheimer's disease
Huntington's disease
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Amoebiasis
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Class
Metabolism; Carbohydrate metabolism; Inositol phosphate metabolism [PATH:cfa00562]
Environmental Information Processing; Signal transduction; Rap1 signaling pathway [PATH:cfa04015]
Environmental Information Processing; Signal transduction; Wnt signaling pathway [PATH:cfa04310]
Environmental Information Processing; Signal transduction; Calcium signaling pathway [PATH:cfa04020]
Environmental Information Processing; Signal transduction; Phosphatidylinositol signaling system [PATH:cfa04070]
Cellular Processes; Cell communication; Gap junction [PATH:cfa04540]
Organismal Systems; Immune system; Chemokine signaling pathway [PATH:cfa04062]
Organismal Systems; Endocrine system; Insulin secretion [PATH:cfa04911]
Organismal Systems; Endocrine system; GnRH signaling pathway [PATH:cfa04912]
Organismal Systems; Endocrine system; Estrogen signaling pathway [PATH:cfa04915]
Organismal Systems; Endocrine system; Oxytocin signaling pathway [PATH:cfa04921]
Organismal Systems; Endocrine system; Thyroid hormone synthesis [PATH:cfa04918]
Organismal Systems; Endocrine system; Thyroid hormone signaling pathway [PATH:cfa04919]
Organismal Systems; Endocrine system; Melanogenesis [PATH:cfa04916]
Organismal Systems; Circulatory system; Adrenergic signaling in cardiomyocytes [PATH:cfa04261]
Organismal Systems; Circulatory system; Vascular smooth muscle contraction [PATH:cfa04270]
Organismal Systems; Digestive system; Salivary secretion [PATH:cfa04970]
Organismal Systems; Digestive system; Gastric acid secretion [PATH:cfa04971]
Organismal Systems; Digestive system; Pancreatic secretion [PATH:cfa04972]
Organismal Systems; Excretory system; Endocrine and other factor-regulated calcium reabsorption [PATH:cfa04961]
Organismal Systems; Nervous system; Glutamatergic synapse [PATH:cfa04724]
Organismal Systems; Nervous system; Cholinergic synapse [PATH:cfa04725]
Organismal Systems; Nervous system; Dopaminergic synapse [PATH:cfa04728]
Organismal Systems; Nervous system; Serotonergic synapse [PATH:cfa04726]
Organismal Systems; Nervous system; Long-term potentiation [PATH:cfa04720]
Organismal Systems; Nervous system; Long-term depression [PATH:cfa04730]
Organismal Systems; Nervous system; Retrograde endocannabinoid signaling [PATH:cfa04723]
Organismal Systems; Sensory system; Inflammatory mediator regulation of TRP channels [PATH:cfa04750]
Organismal Systems; Environmental adaptation; Circadian entrainment [PATH:cfa04713]
Human Diseases; Neurodegenerative diseases; Alzheimer's disease [PATH:cfa05010]
Human Diseases; Neurodegenerative diseases; Huntington's disease [PATH:cfa05016]
Human Diseases; Infectious diseases; Amoebiasis [PATH:cfa05146]
Human Diseases; Infectious diseases; Chagas disease (American trypanosomiasis) [PATH:cfa05142]
Human Diseases; Infectious diseases; African trypanosomiasis [PATH:cfa05143]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
24
AA seq 1115 aa AA seqDB search
MITVVYGPDLVNISHLNLVAFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKL
QVTPEGRIPLKNIYRLFSADRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCP
RPEIDNIFSEFGAKSKPYLTVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPN
NSLAKKGQISVDGFMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLA
GNSSVEMYRQVLLSGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFK
TSPFPILLSFENHVDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYK
ILVKNKKKSHKSSEGSGKKKLSEQVSNTYSDSSSMFEPSSPGAGEADTESDDDDDDDDCK
KSSMDEGTAGSEAMATEEMSNLVNYIQPVKFESFEISKSKNRSFEMSSFVETKGLEQLTK
SPVEFVEYNKMQLSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTVDLAMQINMGMYE
YNGKSGYRLKPEFMRRPDKHFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDM
FGLPVDTRRKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPSLACLRIAVYEEGGKFIGHRI
LPVQAIRPGYHYICLRNERNQPLMLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLME
QRAKQLAALTLEDEEEVKKEADPGETPSEAPSEAGTNPAENGVNHTTSLAPKPPSQALHS
QPAPGSVKAPAKTEDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKT
TDLIKEHTTKYNEIQNDYLRRRAALEKTAKKDSKKKSDPSSPDHGSSTIEQDLAALDAEM
TQKLIDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEIC
EKEKKELKKKMDKKRQEKITEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQ
EKLVEKHKEIRQQILDEKPKLQMDLEQEYQDKFKRLPLEILEFVQEAMKGKISEESNHSS
APPSLASDPGKLNHKPPSSEELEGDNPGKEFDTPL
NT seq 3348 nt NT seq  +upstreamnt  +downstreamnt
atgataacggtggtgtatgggcctgacttagttaacatctcccatttgaatctcgtggct
ttccaagaagaagtggccaaggaatggacaaatgaggttttcagtttggcaacaaacctg
ctggcccaaaacatgtcaagagatgcatttctggaaaaagcctatactaagcttaagctg
caagtcactccagaagggcgcattcctctcaaaaacatataccgcttgttctcagcagac
cggaagcgagttgaaactgctttagaggcttgtagtcttccatcttcaaggaacgattca
atacctcaagaagatttcactccagaagtgtacagagttttcctgaacaacctttgtcct
cgacctgaaattgataatatcttttccgaatttggtgccaaaagcaaaccataccttacc
gttgatcagatgatggattttatcaaccttaagcagcgagatccccggctaaatgaaata
ctttacccacctttaaagcaagaacaagtccaagtattgattgagaagtatgaacccaac
aatagcctcgccaaaaaaggacagatttcagtggatggctttatgcgctatctgagtgga
gaagaaaatggagtcgtttcacctgagaaactggatttgaatgaagatatgtctcagccc
ctttctcactatttcatcaattcctcacacaacacctacctcacagctggccagttggct
ggaaactcctctgttgagatgtatcgccaagtgctcctgtctggttgtcgctgtgtagag
ttggactgctggaagggtcgaactgctgaagaggaaccagtcatcacccatgggttcacc
atgacaaccgaaatatccttcaaggaagtgatagaagcaattgctgagtgtgcatttaag
acgtcaccttttccaattctgctttcatttgagaaccacgtagattccccaaagcagcaa
gccaagatggcggagtattgccgactgatctttggagatgctcttctcatggaaccactg
gaaaaatacccactggaatctggagttcctcttccaagccctatggatttaatgtacaaa
attttggtgaaaaataagaagaaatcccacaagtcgtcagaaggaagtggcaaaaagaag
ctctcagaacaagtctccaacacgtacagtgactcctccagcatgtttgagccctcatct
ccaggagccggggaagctgataccgagagtgatgatgatgatgatgatgatgactgtaaa
aaatcttctatggatgaggggactgccgggagtgaggccatggccacagaagagatgtct
aacctggtgaactatattcaaccagtcaagtttgagtcatttgaaatttcaaaaagtaaa
aatagaagttttgaaatgtcttctttcgtggaaaccaaaggactagagcaactgacaaag
tctccagtggaatttgtagaatataacaaaatgcagcttagcaggatatatccaaaagga
acccgtgtggattcatctaactacatgcctcagctcttctggaatgcaggttgtcaaatg
gttgcacttaattttcaaactgtggacctggctatgcaaataaatatggggatgtatgaa
tacaatgggaaaagtggctacagattaaagccagagttcatgaggagacctgacaagcat
tttgatccattcaccgaaggcatcgtggatgggatagtggccaatactttatctgtcaag
attatttcaggtcagtttctctctgataagaaagttgggacttacgtggaagtggatatg
tttggtttgcctgtggacacaaggaggaaggcatttaagaccaaaacatcacaaggaaat
gctgtaaatcctgtctgggaagaagagcccattgtgttcaaaaaggtggttcttccttct
ctggcctgtttgaggatagcagtttatgaagaaggaggtaaatttatcggtcaccggatc
ttgccagtacaggcaattcggccaggctatcactacatctgtctgaggaatgagaggaac
cagcctctgatgcttccagctgtgtttgtctacatagaggtgaaagactatgtcccagat
acctatgcagatgtgattgaagctttgtcaaatccaatacgatatgtgaatctgatggaa
cagagagctaaacaactggctgctttgacactggaagatgaagaagaagtaaagaaagag
gctgatcctggggaaacaccgtcagaagctccaagtgaagctgggacaaatccagcagaa
aacggagtgaatcacactacatctctggcacccaaaccaccctcccaggccctccacagc
caaccagctccaggctctgtaaaggcacctgccaaaacagaagatcttattcagagtgtt
ttaacagaagtggaagcacagaccattgaagagctaaagcaacagaaatcgtttgtgaaa
cttcaaaagaaacactacaaagaaatgaaagacctggttaaaagacaccacaagaaaacc
acagaccttatcaaagaacacactacaaaatataatgaaattcagaatgactacttgaga
aggagggcagctttggaaaagacagccaaaaaggacagtaagaaaaaatcagatcccagc
agtcctgaccatggttcatcaacaattgagcaagatcttgctgcccttgatgccgaaatg
acccaaaagttaatagacttgaaggacaaacaacagcagcagctgcttaatcttcgacaa
gagcagtattatagtgaaaaataccagaagcgagaacatattaaactgcttattcaaaaa
ttgacggatgttgctgaagaatgtcagaacaatcagttgaagaagctcaaagaaatctgt
gagaaagagaagaaggaattaaagaagaaaatggataaaaaaaggcaggagaagataaca
gaagctaaatccaaagacaaaagtcaaatggaagaggaaaagacagagatgatccggtca
tatatccaggaggtggtgcagtacatcaagaggttagaagaggcacaaagtaaacggcaa
gaaaaacttgtagagaaacacaaggagatacgtcagcagatcctggatgaaaagcccaag
ctgcagatggacttggagcaagagtaccaagacaagttcaaaagactgcccctggagatc
ttggagtttgtgcaggaagccatgaaagggaagatcagtgaagagagcaatcacagttct
gcccctccatccctggcctcagaccctggaaaactgaaccacaagcctccctccagtgag
gagctagagggagacaacccaggaaaagagtttgatactcctctgtga

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