KEGG   Canis familiaris (dog): 485874Help
Entry
485874            CDS       T01007                                 

Gene name
PLCG1
Definition
phospholipase C, gamma 1
Orthology
K01116  
phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
Organism
cfa  Canis familiaris (dog)
Pathway
Inositol phosphate metabolism
Metabolic pathways
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Calcium signaling pathway
NF-kappa B signaling pathway
HIF-1 signaling pathway
Phosphatidylinositol signaling system
VEGF signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Inflammatory mediator regulation of TRP channels
Thyroid hormone signaling pathway
Epstein-Barr virus infection
Pathways in cancer
Proteoglycans in cancer
MicroRNAs in cancer
Glioma
Non-small cell lung cancer
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Class
Metabolism; Carbohydrate metabolism; Inositol phosphate metabolism [PATH:cfa00562]
Environmental Information Processing; Signal transduction; Ras signaling pathway [PATH:cfa04014]
Environmental Information Processing; Signal transduction; Rap1 signaling pathway [PATH:cfa04015]
Environmental Information Processing; Signal transduction; ErbB signaling pathway [PATH:cfa04012]
Environmental Information Processing; Signal transduction; VEGF signaling pathway [PATH:cfa04370]
Environmental Information Processing; Signal transduction; NF-kappa B signaling pathway [PATH:cfa04064]
Environmental Information Processing; Signal transduction; HIF-1 signaling pathway [PATH:cfa04066]
Environmental Information Processing; Signal transduction; Calcium signaling pathway [PATH:cfa04020]
Environmental Information Processing; Signal transduction; Phosphatidylinositol signaling system [PATH:cfa04070]
Organismal Systems; Immune system; Natural killer cell mediated cytotoxicity [PATH:cfa04650]
Organismal Systems; Immune system; T cell receptor signaling pathway [PATH:cfa04660]
Organismal Systems; Immune system; Fc epsilon RI signaling pathway [PATH:cfa04664]
Organismal Systems; Immune system; Fc gamma R-mediated phagocytosis [PATH:cfa04666]
Organismal Systems; Immune system; Leukocyte transendothelial migration [PATH:cfa04670]
Organismal Systems; Endocrine system; Thyroid hormone signaling pathway [PATH:cfa04919]
Organismal Systems; Nervous system; Neurotrophin signaling pathway [PATH:cfa04722]
Organismal Systems; Sensory system; Inflammatory mediator regulation of TRP channels [PATH:cfa04750]
Human Diseases; Cancers; Pathways in cancer [PATH:cfa05200]
Human Diseases; Cancers; MicroRNAs in cancer [PATH:cfa05206]
Human Diseases; Cancers; Proteoglycans in cancer [PATH:cfa05205]
Human Diseases; Cancers; Glioma [PATH:cfa05214]
Human Diseases; Cancers; Non-small cell lung cancer [PATH:cfa05223]
Human Diseases; Infectious diseases; Epstein-Barr virus infection [PATH:cfa05169]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
24
AA seq 1177 aa AA seqDB search
MEFRLKTLSLQATSEDEVNMWIKGLTWLMEDTLQAATPLQIERWLRKQFYSVDRNREDRI
SAKDLKNMLSQVNYRVPNMRFLRERLTDLEQRSSDITYGQFAQLYRSLMYSAQKTMDLPF
LEASALRAGERPELCRVSLPEFQQFLLEYQGELWAVDRLQVQEFMLSFLRDPLREIEEPY
FFLDEFVTFLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEA
YARCLRMGCRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILS
IEDHCSIAQQRNMAQYFKKVLGDTLLTKPVDIAADGLPSPNQLKRKILIKHKKLAEGSAY
EEVPTSVMYSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDE
EEPKEASGSTELHSSEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFV
GDYTLSFWRNGKVQHCRIHSRQDAGAPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMR
LSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKI
KHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYG
ALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQRDDELTFTKSAIIQNVEKQEGGWWRGD
YGGKKQLWFPSNYVEEMVSPAALEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKNN
RLFVFSISMASVAHWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKMMERRKKIALE
LSELVVYCRPVPFDEDKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIY
PKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMAGGHCGYVLQPSTMRDE
AFDPFDKSSLRGLEPYAICIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSIKQKTEFVV
DNGLNPVWPAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPL
KNNYSEDLELASLLVKIDVFPAKENGDLSPFGMSLRERGSDASGQLFHGRAREGSFEARY
QQPFEDFRISQEHLADHFDSRERRAPRRTRVNGDNRL
NT seq 3534 nt NT seq  +upstreamnt  +downstreamnt
atggaattccgcctgaagactctgagcctgcaagctacatctgaggatgaagtgaacatg
tggatcaagggtttaacttggctgatggaggatacattgcaggcagccacacctctgcag
attgagaggtggctgcggaagcagttctactcagtggatcggaatcgtgaggatcgtata
tcagccaaggacttgaagaacatgctgtcccaggtcaactaccgggttcccaacatgcgc
ttcctccgagagcgtctgacggacctggagcagcgcagcagtgacatcacctacgggcag
tttgctcagctgtaccgcagcctcatgtacagcgcccagaagacgatggacctccccttc
ttggaagccagtgccctgagggcaggggagcgcccggagctctgtcgtgtgtcccttcct
gagtttcagcagttcctcctcgagtaccagggggagctgtgggctgttgatcggcttcag
gtgcaggagttcatgctcagcttccttcgagatcctttacgagaaattgaagagccttac
ttcttcctggacgagtttgtcaccttcttgttctccaaagagaacagcgtgtggaattca
cagctggatgcagtgtgcccggacaccatgaacaaccctctgtcccactactggatctcc
tcctcccacaacacgtacctgactggggaccagttctccagcgagtcctctctggaagcc
tatgctcgctgcctgcggatgggctgtcgctgcattgagttggactgctgggatggccca
gatgggatgccagtcatttaccatgggcacacccttaccaccaagatcaagttctcagat
gttctacataccatcaaggagcatgccttcgtggcttcagagtatccggtcatcctgtcc
atcgaggaccactgcagcatcgcccagcagagaaacatggcgcagtacttcaagaaggtg
cttggggacacactcctcaccaagcctgtggacatcgccgctgacgggctcccctcaccc
aaccagctcaagaggaagatcctcatcaagcacaagaagctggcagagggcagtgcctac
gaagaggtgcctacgtcagtgatgtactccgagaacgatatcagcaactccatcaagaat
ggcatcctctacctggaggacccggtgaaccatgagtggtacccccactacttcgttctg
accagcagcaagatctactactctgaggagaccagcagtgaccagggcaatgaggatgag
gaggaacccaaggaggccagtggcagcacagagctgcactccagtgagaagtggttccac
gggaagcttggagcaggacgggatggacggcacattgccgagcgcctgctcaccgagtat
tgcattgagaccggggcccctgatggctccttcctcgtgcgggagagcgagaccttcgtg
ggcgactataccctctctttctggaggaacgggaaagtccagcactgtcggatccattcc
cggcaggatgctggggcccccaagttcttcttgacagacaacctggtctttgattcgctc
tatgacctcatcacgcactaccagcaagtgcccctgcgctgcaacgaatttgagatgcgc
ctttcagagccggtcccacagaccaatgcccacgagagcaaagagtggtaccacgccagc
ctgaccagagctcaggccgagcacatgctgatgcgtgttccccgggatggggccttcctg
gtgaggaaacggaatgagcccaactcctatgccatctctttccgggccgagggcaagatc
aaacattgccgcgtccagcaggagggccagactgtgatgctgggcaactctgagtttgac
agcctcgtggacctcatcagctactatgagaagcacccgctataccgcaaaatgaagctg
cgctatcccatcaatgaggaagcgctggagaagataggcacagctgagcctgactatgga
gccctgtatgagggacgcaaccctggcttctatgtggaggcaaatcctatgccgactttt
aagtgtgccgtcaaagccctctttgactacaaggctcagagggatgacgagctgacattc
acgaagagcgccatcatccagaatgtggagaagcaagaaggtggctggtggcggggggac
tacggggggaaaaagcagctctggttcccgtcaaactacgtagaagagatggtcagccct
gcagccctggagcctgagagggagcacttggatgagaacagccccctgggggatttgctc
cgtggggtcttggatgtgccagcctgtcagattgctatccgtcctgagggcaagaacaac
cggctcttcgtcttctccatcagcatggcttcagtggcacactggtccttggatgtcgct
gctgattcacaggaagagctgcaggactgggtgaagaagatccgagaagtggcccagacg
gcagacgccaggctcacggaggggaagatgatggagcgcaggaagaagatcgccctggag
ctctccgagctggttgtctactgcaggccggttcccttcgatgaagacaagattggcaca
gaacgtgcctgctaccgggacatgtcatcctttccggaaaccaaggctgagaaatatgtg
aacaaggccaaaggcaagaagttcctccagtacaaccggctgcagctctcacgcatctac
cccaagggccagcggctagactcctccaattatgaccccctgcccatgtggatctgtggc
agtcagctcgtagccctcaacttccagaccccagacaagcccatgcagatgaaccaggcc
ctcttcatggccggcggccactgcggctacgtgctgcagccgagcaccatgcgggacgag
gcctttgatccctttgacaagagcagcctccgaggcctggaaccatatgccatctgcatt
gaggtgctgggggctcggcacctgccaaagaatggccgaggcatcgtgtgtcctttcgtg
gagattgaagtggccggagcagagtacgacagcatcaagcagaagacagagttcgtggtg
gacaatggactgaaccctgtgtggcctgctaagcccttccacttccagatcagtaaccca
gaattcgcctttttgcgctttgtggtgtatgaggaagacatgtttagtgaccagaacttc
ctggctcaggctacattcccggtgaaaggcctgaagacaggatacagagctgtgcctttg
aagaacaactacagtgaggacctagagctggcctccctgctcgtcaagatcgacgtgttc
cctgccaaggagaatggggacctcagtcccttcgggatgtctcttcgggagcgaggctct
gatgcctcaggccagctgttccatggccgggcccgtgaaggttcctttgaggcccgctac
cagcagccatttgaggactttcgtatctcccaggagcacctggcagaccattttgacagt
cgggaacggagggccccacggaggacacgggtcaacggagacaaccgcctctag

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