KEGG   Canis familiaris (dog): 486808Help
Entry
486808            CDS       T01007                                 
Gene name
PLCE1
Definition
phospholipase C, epsilon 1 (EC:3.1.4.11)
Orthology
K05860  
phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
Organism
cfa  Canis familiaris (dog)
Pathway
Inositol phosphate metabolism
Metabolic pathways
Calcium signaling pathway
Phosphatidylinositol signaling system
Proteoglycans in cancer
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Class
Metabolism; Carbohydrate metabolism; Inositol phosphate metabolism [PATH:cfa00562]
Environmental Information Processing; Signal transduction; Calcium signaling pathway [PATH:cfa04020]
Environmental Information Processing; Signal transduction; Phosphatidylinositol signaling system [PATH:cfa04070]
Human Diseases; Cancers; Proteoglycans in cancer [PATH:cfa05205]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
28
AA seq 2309 aa AA seqDB search
MTSEGMAASVLTPVTQRKVTFAPSAVDESSEKVSDISVPKAHSVKQSEQTSTIPWMNKLK
EESSGSNLPKILSIAREKIASDENSNEECWTESTPVSVKNLNINHNNILTNRQCVLPQSQ
SYDTCNSVMEEDPCLETGISSSLERKVFPGIQLEVNRPPMDFRPPGLMDFSTLGSQSAIV
DTGQAHPDSNKAAFQIFNYKVDRRMSDTFCTLSGDLILDDCGNCVPLSSGFGGEQKKNYV
AYTCKLMELAENCDNENGQLQCDDYDALDDKYLCFEDSCQRDSVVCSSDSFRREDLTNSP
PAKTFLSHFEDFPDNGEDVEDFLKNKKERSTLLVRRFCKNDREVKKSVYTGTRAIMRTLP
SGHIGLEAYSYIDQKRSGPLLPRGRVLEQLPVVAIRQDGSQCLSEAQWYRIYNAVRREEE
IENTIGSLLHYFTKLPASKTAHERISVGPCLKQCVRDTICEYRATLQRTSISQYITGSLL
EATTSLGARSGLLSTFGGSTGRMMLKERQPGTSMANSSALPSSSAGISKELIDLQPLIQF
PEEVASILMEQEQNIYRRVLPVDYLYFLTRDLGTPECQTPLPCLKASISASILSSQNGEH
NALEDLVMRFNEVSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGL
RSRKVLKMWQFMDQSDLETMRSLKDAMAQHESSCEYRKVITRALHIPGCKVVPFCGVFLK
ELCEVLDGASGLMKLCPRYNSQEETLEFVADYSGQDNFLQRVGHNGLKNSEKESTVNSIF
QIIRSCSRSLEAEEEDSPSEGNSSRKNSLRDKARWQFIIGDLLDSENDIFEQSKEWDSPS
SEEPQKAFDHGTELIPWYVLSIRADVHQFLLQGATVLRYDQDTHLSARCFLQLQPDNSTL
TWIKPTAASPASARAKLGVLSNTSEPGKFPSPGSAGLSGLAEGVLDLFSAKAVYMGHPSI
DIHTVCVQNKLGSMFLSETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTRAVRK
MRKFPDQRQQWLRKQYVSLYQEDGRYEGPTLAHAVELFGGRRWSTRNPSPGTSAKSAEKP
SVQRNNTLGISTTKKKKKILIRGESGEAADDEMATRKAKMHRECRSRSGSDPQDMNEQEE
SEANAIMSPPNTLPSRRAHSLTTAGSPNLSAGTSSPIRPVSSPVLSSSNKSPSSAWSSSS
WHGRIKGGMKGFQSFMVSDSNMSFVEFVELFKSFSVRSRKDLKDLFDIYAVPCNRAGSES
APLYTNLTIDENTSDLQPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNG
TGIESTSLGIFGVGILQLNDFLVNCQGEHCTYDEILSIIQKFEPSISMCHQGLLSFEGFA
RFLMDKDNFASKNDESQENIKDLQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQ
GCRSVELDCWDGDDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSL
PQQRKMAEIFKTVFGEKLVAKFLFESDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDI
LKQKAHQLASMQAQAYNGGNVNPPPANNEEEEDEEDEYDYDYESLSDDNILEDRPENKSC
NDKLQFEYNEEIPKRIKKADNSAFNKGKVYDMELGEEFYLPQNKKESRQIAPELSDLVIY
CQAVKFPGLSTLNASGSNRGKERKSRKSIFGNNPGRMSPGETASFNKASGKSSCEGMRQA
WEESSSPLNPTTSLSAIIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTACQLLRTYPAA
TRIDSSNPNPLLFWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCP
MYQKFSPLERDLDNMEPAVYSLTIVSGQNVCPSSSTGSPCIEVDVLGMPLDSCHFRTKPI
HRNTLNPMWNEQFLFRVHFEDLIFLRFAVVENNSSAITAQRIIPLKALKRGYRHLQLRNL
HNEVLEISSLFINSRRMEENSSSSATPASLMFNTEERKCLQTHRVTVHGVPGPEPFTVFS
ISGGTKAKQLLQQILTTEQDTKPIVTDYFLMEEKYFISKEKNECRKQPFQRVIGPEEEIM
QILSSWFPEEGYVGRIVLKTQQENLEERSIVQDEKEVILSSEEESFFVQVHDVSPEQPRT
VIKAPRVSTAQDVIQQTLCKAKYSYSILSNPNPSDYVLLEEVVKDATKKSSTPKSSQRVL
LDQECVFQAQSKWKGAGKFILRLKEQVQASREDKRKGISFASEFKKFTKSTKQPRGLTSS
QVLASESVQNKEEKPTGSLSSSDTTDSRQ
NT seq 6930 nt NT seq  +upstreamnt  +downstreamnt
atgacttctgaaggaatggcagcttctgttctcacacctgtgactcaaagaaaagtgaca
tttgctccatcggctgtagatgaaagtagtgaaaaggtctcagacatcagtgttccaaag
gcacatagtgtcaagcagagtgagcagacttctaccatcccgtggatgaacaagcttaaa
gaagaatcttctggaagcaacttgcccaaaattctctccatagcaagggagaaaatagca
agtgatgagaacagcaatgaagagtgctggacggaaagcacaccagtttctgtgaaaaac
cttaacattaaccataacaacatcctgacaaaccgccagtgcgtccttcctcagagccag
tcttatgacacgtgcaattctgtcatggaggaagacccatgtttagaaactggaatctca
tcctcactggaaagaaaggtattccctggaattcaactggaagtcaacagacctcccatg
gactttaggcctccaggcctaatggactttagtaccttaggaagtcagtcagccattgta
gatactggccaggcgcaccctgacagcaacaaagcagcatttcaaatctttaattataaa
gttgacagaaggatgtctgacactttctgtaccctgtcaggtgacttgatattggatgac
tgtggaaactgtgtgccactgtcatctggttttggcggggagcaaaagaaaaattacgtg
gcatatacctgtaaactcatggaattggctgaaaactgtgataatgagaatggacagctg
cagtgtgatgattatgatgccttggatgacaaatacttgtgctttgaagattcttgccaa
agggacagtgtggtatgttcaagtgacagctttcgcagggaggacctaactaacagtcca
cctgccaagacctttctgagccattttgaagacttccctgataatggtgaagatgtagaa
gattttttaaaaaacaaaaaggagagatccactttgttagtgaggagattttgtaaaaat
gacagagaagtaaagaaatctgtgtatactgggacaagggcaatcatgagaactctgcct
tctggtcacattgggctggaagcttacagttacatcgatcagaagagaagtggtccctta
ttaccccgtgggagagttctggaacagctgccagtggtggcaattaggcaagatgggagc
cagtgcctgtcagaagcccagtggtatcggatctacaatgcagtgagaagggaagaagaa
atagaaaataccattggatctcttctccattactttaccaagctcccagcctccaagaca
gcccatgaaaggattagtgttggtccatgcctaaagcagtgtgtccgagacaccatatgt
gagtatcgtgccaccctccagaggacgtccatatctcagtacatcacgggttcgctccta
gaagcaaccacatctttaggagcgagaagtggcctactcagtacttttggaggatccact
ggacgaatgatgctaaaagaacgccagccaggcacctccatggccaattccagtgccctc
ccttcaagttccgctggaatcagcaaggagctgattgacctgcagcctctcattcagttc
ccagaggaagtcgccagcatcctgatggagcaggaacagaacatttaccgaagggtctta
ccagttgactatctttacttcttgacccgggacttgggcactccagaatgccagacaccc
ctgccctgcctcaaagcatccatctcagcttcaattcttagctcccagaacggagagcac
aatgccctggaagatcttgtgatgagatttaatgaggtgagctcctgggtgacatggctg
atcctcacggcgggctccatggaggagaagcgagaagtcttctcctatttggtgcatgtg
gccaaatgctgctggaacatgggcaactacaatgctgtcatggagttcttggctggtctc
aggtcaagaaaagttttaaaaatgtggcagtttatggaccaatctgacctcgagaccatg
aggagcctgaaggacgccatggctcagcatgaatcttcctgcgaatatcggaaggtgata
acgagggctctgcacatacctggctgtaaagtggttccattctgtggagtgtttctgaag
gagctctgtgaagtactggacggagcctctggcctcatgaagctttgcccgaggtacaat
tcccaagaagaaactctagagtttgtagcagattacagtggacaagataatttcttacaa
cgagtggggcataatggcttaaagaattcagagaaggagtccactgtcaacagcatcttt
caaatcattaggagctgcagccgaagtctggaggctgaggaagaggacagccccagtgaa
gggaacagctctaggaaaaattctttaagggacaaagcccgatggcaatttataatcgga
gatttgttggattccgaaaatgacatctttgagcaatccaaagaatgggactctcccagc
tcagaagagcctcagaaagcctttgaccatgggacagagctgatcccttggtacgtgctg
tccatccgagcagatgtgcaccagttcctgctacagggcgccaccgtcctccgctacgac
caggacacgcacctctctgcccgctgcttcctccagcttcagcctgacaatagcaccttg
acatggataaagcccacagctgcctccccggccagtgctagagcaaaactcggtgtgctg
agcaacacgtctgagcctggcaagttcccgtcaccaggcagtgccggactaagcggcctg
gccgagggggtcctggatctgttttcagcaaaggctgtgtacatgggacaccctagcatt
gatatccacactgtgtgtgtccagaacaaactcggtagcatgtttctctcagagactggc
gtgaccctgctctacgggctccagaccacagacaatagattattgcactttgtggcaccc
aaacacactgctaagatgctcttcagtggattgctagaactcacgagggccgtgaggaag
atgagaaagttccctgaccagaggcagcagtggctgcggaaacagtatgttagcctctat
caggaggacggacggtatgagggcccaactttggctcatgctgtggagttgtttggtggc
cggcgatggagtacacgcaatcccagccctgggacatctgcaaagagtgctgagaagccc
agtgtgcagagaaacaacaccttgggcataagcaccaccaagaaaaagaagaaaatcctt
ataaggggtgagagtggagaggcagccgacgatgagatggccacccggaaggccaaaatg
cacagggagtgtcgcagccggagtggttctgacccacaagacatgaatgagcaagaagaa
tctgaggcaaatgccatcatgagccctcctaacactctgccttccagaagagcccactct
ttgactacagctgggtcccctaatttgtctgccgggacatcatctcccatcaggccagtg
tcctcccctgtgctgtcttcttcaaacaagagcccgtccagtgcttggagcagcagcagc
tggcatggaaggatcaaaggaggaatgaagggttttcagagcttcatggtttcagacagt
aacatgagttttgttgaatttgttgagctgttcaaatcattcagtgtgaggagccgcaag
gacctgaaggatctctttgacatctacgctgtgccctgcaatcgggccggctctgagtcg
gccccgctctacaccaacctaacaatagacgaaaacaccagcgatcttcagcctgaccta
gatttattgaccagaaacgtctcggatttggggttgttcattaagagtaaacagcagctg
tcagacaaccagaggcagatttctgatgccattgctgctgcaagtatcgtgacgaatggc
actgggatcgagagcacatctttgggcatctttggggttggcatactccagctcaatgac
ttcctagtcaactgccagggagaacactgcacttacgatgaaatcctcagcatcatccag
aagttcgagcctagcattagtatgtgtcatcagggcctactgtcctttgaaggatttgca
aggtttctgatggataaagataattttgcctccaaaaatgatgagtcacaggagaacatt
aaagatttgcagctgcctctctcctactattacattgagtcttcacacaatacctacctc
acaggccaccagctcaaaggagagtcatcggtagaactctatagccaggtcctcctgcaa
ggctgtagaagtgtagagttggactgctgggatggagatgacgggatgcccatcatctat
cacggacacacactaacaaccaagatccccttcaaggaggtggttgaagccatcgaccgc
agtgccttcatcaactctgacctgcccatcatcatatcgattgagaaccactgctcgttg
cctcagcaacgaaaaatggcagaaattttcaagactgtgtttggagaaaaactggtggct
aaattcctgtttgagagcgatttctcagatgatccaatgcttccctcacctgaccaactt
aggaggaaagtgcttcttaaaaataagaagctaaaagcccaccagacaccagtggatatc
ttaaagcaaaaggctcatcagttagcatccatgcaagctcaggcttataatgggggaaat
gtcaaccctccacctgctaataacgaggaagaggaagatgaagaggacgaatatgattat
gactatgaatccctgtctgatgacaacattctagaagacagacctgaaaataaatcatgt
aatgacaagcttcagtttgagtataacgaagaaatccccaagaggataaagaaagcagat
aattctgctttcaacaaaggaaaggtttatgacatggaactgggagaagaattttatctt
cctcagaataaaaaggaaagcagacagattgcaccagagctttctgaccttgtcatctac
tgccaagcggtaaagtttccggggctgtcaactctaaatgcatctggctctaacagagga
aaagagaggaaaagcaggaagtccatttttggcaacaatccgggcagaatgagccctggg
gagacagcatcgtttaacaaagcatctggaaaaagttcctgtgaaggaatgcgacaggcg
tgggaggaatcttcttcccccctcaacccaaccacatccctcagcgctatcattagaact
cccaaatgttaccatatctcatcgctgaatgaaaatgccgccaaacgtctgtgtcgcagg
tattctcagaaactgatccagcacactgcctgtcagctgctgaggacttacccggctgcc
acacgcatcgactcctccaaccccaatcctctcttgttctggctccatgggatacagctc
gtggcactcaactaccagacagatgatctccctttacatttaaatgctgccatgtttgag
gccaacggtggctgtggttatgttttgaaaccccccgttctgtgggacaagaactgtccc
atgtaccagaagttttcacccttggaaagagacctggacaacatggagcctgccgtctat
tccttaactattgtctctggtcaaaacgtgtgcccaagtagcagcacgggaagcccatgt
atcgaagtggacgtgctgggcatgcccctggacagttgccacttccgcacaaaacccatc
caccggaacactttgaaccccatgtggaatgaacagtttctcttccgggttcactttgaa
gatctcatattcctgcgttttgcagttgtggaaaacaatagctcagccataaccgctcag
agaatcatccccctcaaggctttaaaacgaggatatcgacatcttcagctgcgaaacctc
cacaatgaagtcttggaaatctctagtttattcataaacagcagaaggatggaagaaaat
tcctccagcagtgccacgccagcctctttgatgtttaatacagaagaaagaaaatgtttg
cagactcacagagtcacagtgcatggggtcccaggtccagagccctttactgttttctcc
ataagtggaggcacgaaggcaaagcagcttctccaacagattctaactactgaacaagac
accaaacctattgtcacagactattttttgatggaagaaaaatattttatatctaaagaa
aagaatgaatgcaggaaacaaccatttcagagagtcatcggtccagaagaagagatcatg
cagattttaagcagctggtttccagaggaaggatatgttggcaggattgtcttaaaaacc
cagcaggaaaacctagaagagagaagcattgttcaagatgagaaagaggtgatcttgagc
tcggaggaggagagcttctttgtccaagtgcatgacgtttctccagagcaacctcggacg
gtcatcaaagcgccccgtgtcagcaccgctcaggatgtcattcaacagaccttatgcaaa
gccaaatattcctatagcatcctgagtaaccccaacccgagtgactatgtgcttctggaa
gaggtggtgaaagatgctaccaagaagtcctccaccccaaagtcctcccagcgggtcctt
ttggaccaagagtgtgtgtttcaagcccagagcaagtggaaaggtgctggaaaattcatc
ctcaggctaaaggagcaggtgcaggcatcccgagaagataaaagaaaaggcatttctttc
gcaagtgaattcaagaagttcaccaaatcaactaaacagccccgaggactcacatcttct
caggtcttggcctcagaaagtgtccaaaacaaggaggagaagcccacgggcagcttgtcc
tccagtgacaccacagactcccgacaataa
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