KEGG   Canis familiaris (dog): 487107Help
Entry
487107            CDS       T01007                                 

Gene name
GAD2, GAD65
Definition
glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) (EC:4.1.1.15)
Orthology
K01580  
glutamate decarboxylase [EC:4.1.1.15]
Organism
cfa  Canis familiaris (dog)
Pathway
Alanine, aspartate and glutamate metabolism
beta-Alanine metabolism
Taurine and hypotaurine metabolism
Butanoate metabolism
Metabolic pathways
GABAergic synapse
Type I diabetes mellitus
Module
GABA (gamma-Aminobutyrate) shunt
Brite
KEGG Orthology (KO) [BR:cfa00001]
 Metabolism
  Carbohydrate metabolism
   00650 Butanoate metabolism
    487107 (GAD2)
  Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    487107 (GAD2)
  Metabolism of other amino acids
   00410 beta-Alanine metabolism
    487107 (GAD2)
   00430 Taurine and hypotaurine metabolism
    487107 (GAD2)
 Organismal Systems
  Nervous system
   04727 GABAergic synapse
    487107 (GAD2)
 Human Diseases
  Endocrine and metabolic diseases
   04940 Type I diabetes mellitus
    487107 (GAD2)
Enzymes [BR:cfa01000]
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.15  glutamate decarboxylase
     487107 (GAD2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
2
AA seq 585 aa AA seqDB search
MASPGSGFWSFGSEDGSGDPENPSTARAWCQVAQKFTGGIGNKLCALLYGDAEKPAESGG
SEPPRATSRKAACACNQKPCSCPKAEVNYAFLHATDLLPACDGERPTLAFLQDVMDILLQ
YVVKSFDRSTKVIDFHYPNELLQEYNWELADQPQNLEEILMHCQTTLKYAIKTGHPRYFN
QLSTGLDMVGLAADWLTSTANTNMFTYEIAPVFVLLEYVTLKKMREIIGWPGGSGDGIFS
PGGAISNMYAMLIARFKMFPEVKEKGMAAVPRLIAFTSEHSHFSLKKGAAALGIGTDSVI
LIKCDERGKMVPSDLERRILEAKQKGFVPFLVSATAGTTVYGAFDPLLAVADICKKYKIW
MHVDAAWGGGLLMSRKHKWKLSGVERANSVTWNPHKMMGVPLQCSALLVREEGLMQSCNQ
MHASYLFQQDKHYDLSYDTGDKALQCGRHVDVFKLWLMWRAKGTTGFEAHIDKCLELAEY
LYSIIKNREGYEMVFDGKPQHTNVCFWYVPPSLRVLEDNEERMNRLSKVAPVIKARMMEY
GTTMVSYQPLGDKVNFFRMVISNPAATHQDIDFLIEEIERLGQDL
NT seq 1758 nt NT seq  +upstreamnt  +downstreamnt
atggcatctccaggctctggcttctggtccttcgggtctgaagatggctccggggatccc
gagaaccccagcacagcgagagcctggtgtcaggtggcccagaagttcacgggcggcatc
ggaaacaagctgtgcgccctgctctacggagatgccgagaagcccgcggagagtggcggg
agcgagcccccgcgcgccacctccaggaaggccgcctgcgcttgtaatcagaagccttgc
agctgccccaaagcggaggtcaactatgcgtttctacacgcaacagacctgctgccagcc
tgtgatggagaaaggcccacgttggcgtttctgcaagatgttatggacattttgcttcag
tatgttgtgaaaagtttcgatagatcaaccaaagtgattgatttccattaccctaatgag
ctccttcaagagtataactgggaattggcagaccaaccacaaaatttggaggaaattttg
atgcattgccaaacgactctaaaatatgcaattaaaacagggcatcccagatatttcaat
cagctttccactggactggatatggttggattagcagcagactggctgacatcaacagca
aacacaaacatgttcacctatgaaattgctccagtatttgtgctcttggaatatgtcaca
ctaaagaaaatgagagaaatcattggctggccgggaggctctggcgatgggatattttct
cctggtggcgctatttctaacatgtatgccatgctgatcgcacgctttaagatgttccca
gaagtcaaggagaaaggaatggctgcggttcccaggctcattgccttcacatctgagcat
agtcacttttctctcaagaagggagctgcagctttggggattggaacagacagcgtgatt
ctgattaaatgtgatgagagggggaaaatggtcccatctgatcttgaaagaaggatcctt
gaagccaaacaaaaaggatttgttcctttccttgtgagcgccacagctgggaccaccgtg
tatggagcattcgaccccctcttagcagttgctgacatttgtaaaaagtacaagatctgg
atgcatgtggatgctgcttggggtgggggattactgatgtcccggaagcacaaatggaag
ctgagcggcgtggagagggccaactctgtgacatggaacccacacaagatgatgggcgtc
cctttacagtgctccgctctcctggttagagaagagggattgatgcagagttgcaaccag
atgcatgcctcctacctcttccagcaagataaacactatgacctgtcctatgatactggg
gataaggccttacagtgtggacgccacgttgatgtttttaaattatggctaatgtggagg
gcaaagggcaccactgggtttgaagcacatattgataagtgcctggagctggctgagtat
ttatacagtatcataaaaaaccgagaaggatacgaaatggtgtttgatggaaagcctcag
cacacaaatgtctgcttctggtacgtgcctccaagtttgcgtgtcctggaagacaatgaa
gagagaatgaaccgcctctcaaaggtggccccagtgattaaagcccgaatgatggagtat
gggaccacaatggtcagctatcagcccttgggagacaaggtcaatttcttccgcatggtt
atctcaaatcccgcagcaactcaccaagacatcgacttcctgattgaagaaatagaacgc
cttggacaagatttataa

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