KEGG   Canis familiaris (dog): 487119Help
Entry
487119            CDS       T01007                                 

Gene name
ITGA8
Definition
integrin, alpha 8
Orthology
K06584  
integrin alpha 8
Organism
cfa  Canis familiaris (dog)
Pathway
PI3K-Akt signaling pathway
Focal adhesion
ECM-receptor interaction
Cell adhesion molecules (CAMs)
Regulation of actin cytoskeleton
Hypertrophic cardiomyopathy (HCM)
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:cfa00001]
 Environmental Information Processing
  Signal transduction
   04151 PI3K-Akt signaling pathway
    487119 (ITGA8)
  Signaling molecules and interaction
   04512 ECM-receptor interaction
    487119 (ITGA8)
   04514 Cell adhesion molecules (CAMs)
    487119 (ITGA8)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    487119 (ITGA8)
  Cell communication
   04510 Focal adhesion
    487119 (ITGA8)
 Human Diseases
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    487119 (ITGA8)
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    487119 (ITGA8)
   05414 Dilated cardiomyopathy (DCM)
    487119 (ITGA8)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
2
AA seq 1178 aa AA seqDB search
MKEIQTGNGERVNEANRRDGNDITSEGQVKSTLPIAQAKNHGAVVIPPLLKFMSKYCWLY
LQNTSGRAGDVPLAQATPVLGSPRDSSILRRGGWSRLQRRRSTAVRAQPAVTERRGAGAV
GPGQPALSFASPPSPFWPPASLSTPSPSLRPDPHPGPPPWSRGDGVARARLCGAQGVTFL
HALRRASVLVGAPKANTSQPDIVEGGAVYYCPWPAQGSARCKQIPFDNTNNRKIRVNGTK
EPIEFKSNQWFGATVKAHKGEVVACAPLYHWRTLKPTPEKDPVGTCYVAIQNFSAYAEYS
PCRNSNADPEGQGYCQAGFSLDFYKNGDLIVGGPGSFYWQGQVITASIADIIANYSFKDI
LRKLAREKQTDVAPASYDDSYLGYSVAAGEFTGDSEQELVAGVPRGAQNFGYVSIINSTD
MTFIQNFTGEQMASYFGYTVTVSDVNNDGMDDVLIGAPLFMEREFESSPREVGQVYLYLQ
ENALVFRDPQILAGTEVFGRFGSAVAHLGDLNQDGYNDIAIGAPFAGKDQRGQVLIYNGN
KDGLNRKPSQILQGMWASQTIPSGFGFTLRGDSDIDRNDYPDLIVGAFGTGKVAVYRARP
VVTVDAQLLLHPMIINLENKTCQIPESLSSVACFSLSVCASVTGQSISNTIGLTAEVHLD
SLKQKGAVKRTLFLDNHESHLIFPLTIKRQRSLQCQDFVVYLRDETEFRDKLSPINISLN
YSLDESTFKEGLEVKPILNYYRENTVTQQAHILVDCGEDNMCIPDLKLSARPDKHQVIIG
DENHLTLIINARNEGEGAYEAELFVMIPEEADYVGIERSNKGLRPLSCEYEMENITRMVV
CDLGNPMVAGTNYSLGLRFAVPRLEKTNMSINFDLQIRSSNKDNPDSNFVSLQINITAVA
QVEIRGVSHPPQIVLPIHNWEPEEEPRKEEGIGPLVEHIYELHNIGPSTISDTLLEVGWP
FSARDEFLLYIFHVQTLGPLRCQTNPDINPQDIKPATPPEDTPELSAFLRNSTIPHLVRR
RDVGVLEPHRQSPAKILNCTNIECLQISCAVGQLEGGESAVLKVRSRLWARTFLQRKNDP
YTLASLVSFKVKKMPYKDQPAKLPEGSIAIKTSVIWATPNVSFSIPLWVIILAILLGLLV
LAILTLALWKCGFFDRARPPQDDMNDREQLTDDKAAEA
NT seq 3537 nt NT seq  +upstreamnt  +downstreamnt
atgaaggaaatccaaacaggaaatggagagagagtgaatgaggctaataggagagatggc
aacgacatcacctcagaaggtcaggtaaaatccactcttcccattgctcaggccaaaaac
catggtgctgtcgtcattcctccccttctcaagttcatgagcaaatactgttggctgtac
cttcaaaatacatccggaagagccggagacgtgccgcttgcacaggcaacgccagtcctg
gggagcccccgggactcgagcatcctgcgaaggggcggctggagccggttacagcgacgc
cgcagcacggctgttcgcgcacagcctgcggtaaccgagcgtcggggcgcgggcgccgtg
ggccccgggcagccggctctgtccttcgcttccccgccaagccccttctggcctcccgct
tcgctctccaccccgagtccgtctctgcgccccgacccccaccccgggcccccaccctgg
tctcggggagacggcgtcgcgcgcgcacgcctgtgcggtgcccaaggagtgacttttctc
cacgcccttcgcagggccagcgtgttggtgggggcgcccaaagccaacaccagccagccc
gacatcgtggaagggggagccgtctactactgtccctggcccgcccaggggtctgcgcgg
tgcaagcagataccgtttgacaacaccaacaacagaaaaatcagagttaatggaaccaag
gaacctatagaatttaaatcaaatcagtggtttggagcaacagtgaaagctcacaaagga
gaagttgtggcctgtgctcctttatatcactggaggactcttaaaccaacaccagaaaag
gacccagttggcacctgctatgtagcgatccagaacttcagtgcatatgcagaatattct
ccttgtcggaacagtaatgctgatccagaaggccagggttactgccaagcgggatttagt
ctggatttttataagaatggagacctcatagtaggaggaccgggaagtttctattggcaa
ggtcaggtgatcactgccagtattgccgatatcattgcaaattactcattcaaggatatt
ctaaggaaattggctcgagaaaagcagacagacgtggctccagcttcctatgatgacagt
taccttggatattcagttgctgctggggaatttactggagactctgagcaagaactggtt
gctggcgttccaagaggagcacagaattttggatatgtttcaatcattaactctacagat
atgactttcattcagaatttcactggcgaacagatggcatcttattttggatatacggtc
acagtgtcagatgttaacaatgatggaatggatgacgtattgattggggcacctctcttt
atggaacgtgaatttgagagcagccctagggaagtagggcaagtttacctgtatttgcaa
gagaacgcacttgtcttcagggacccacaaatcctggccggcactgaggtcttcgggaga
ttcggtagtgccgtggctcacttaggagacctgaaccaagatggatacaatgacattgcc
atcggtgcacccttcgcaggcaaggatcaaagaggccaagtactcatttacaatgggaac
aaagatggcttaaacaggaagccttcccaaattctacagggaatgtgggcctctcagacc
attccttcgggcttcggttttaccctaagaggagactcagacatagacaggaatgattac
ccagatttaatcgtaggtgcattcgggacaggaaaagtagctgtttacagggcaaggcca
gttgtcactgtagacgcccagcttttgctgcacccaatgattatcaatctggaaaataaa
acatgccagattccagagtctttgtcatctgtggcctgcttctctttaagcgtatgtgca
tctgtaacaggccagagcatttcaaatacaataggcctgactgccgaggtgcacttggac
tccctgaaacaaaaaggagccgtgaaacgcacgctcttccttgacaaccatgagtcacat
ctcattttccccctcaccataaagcggcagagatccctccaatgccaggattttgtcgtt
taccttagagatgaaactgaattccgagataaattatctccaatcaacattagtttgaat
tacagtttggacgaatccacctttaaagaaggcctggaagtgaaaccaatattgaattac
tacagggaaaacactgttacccaacaggctcacatcctggtggactgtggagaagacaac
atgtgcattcctgacttgaagctctcagctagaccagataagcatcaggtcatcattgga
gatgaaaaccatcttacgctcataatcaatgcaagaaatgaaggagaaggtgcctacgaa
gctgaactctttgtgatgataccagaagaggcagattatgttgggattgaacgcagcaac
aaggggttgcgaccactgagttgtgagtacgagatggaaaatataaccaggatggtggtg
tgtgaccttgggaaccctatggtggctggaacaaattattctctgggcctccgatttgca
gttccacgtcttgagaaaacaaacatgagcattaacttcgatctccaaatcagaagttcc
aacaaggacaacccagacagcaattttgtgagcctgcaaatcaacatcactgctgtagct
caagtagaaataagaggagtatcccaccctccgcagattgttttgcccattcataactgg
gagccagaagaggagccccgcaaagaggaaggaattggtccactggtggaacatatttat
gagctgcacaatattggaccaagtaccatcagcgacacccttctggaagtgggctggcca
ttctctgcccgggacgaatttctcctctacatttttcatgtccaaactctgggacctcta
cggtgtcaaacaaatcctgatattaacccacaggatataaagcccgccacccccccagag
gacacccccgagctgagcgcctttttgcgaaactcgaccatccctcatcttgtccggagg
agagatgtgggggtgctggagccccacagacagagccccgcaaaaatcctgaattgtaca
aatatcgagtgcttacagatctcctgtgcagtggggcagctagaaggaggagaaagcgct
gtcctaaaagtcagatcacggttatgggccaggacctttctccagagaaaaaatgatccc
tatactcttgcatccctggtgtccttcaaagttaagaagatgccttataaagatcagcca
gcaaaactcccagagggaagcatagcaattaagacatcagttatttgggcaaccccaaat
gtttccttttcaatcccattatgggtaataatactagcaatacttcttggattattggtt
ctggccatcttaaccttagctttatggaagtgtggattctttgacagagcaagacccccc
caagatgatatgaatgacagggagcaactgacagatgacaaagccgctgaggcatga

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