KEGG   Canis familiaris (dog): 487633Help
Entry
487633            CDS       T01007                                 

Gene name
HEXA
Definition
hexosaminidase A (alpha polypeptide)
Orthology
K12373  
hexosaminidase [EC:3.2.1.52]
Organism
cfa  Canis familiaris (dog)
Pathway
Other glycan degradation
Amino sugar and nucleotide sugar metabolism
Glycosaminoglycan degradation
Glycosphingolipid biosynthesis - globo series
Glycosphingolipid biosynthesis - ganglio series
Metabolic pathways
Lysosome
Module
Keratan sulfate degradation
Brite
KEGG Orthology (KO) [BR:cfa00001]
 Metabolism
  Carbohydrate metabolism
   00520 Amino sugar and nucleotide sugar metabolism
    487633 (HEXA)
  Glycan biosynthesis and metabolism
   00531 Glycosaminoglycan degradation
    487633 (HEXA)
   00603 Glycosphingolipid biosynthesis - globo series
    487633 (HEXA)
   00604 Glycosphingolipid biosynthesis - ganglio series
    487633 (HEXA)
   00511 Other glycan degradation
    487633 (HEXA)
 Cellular Processes
  Transport and catabolism
   04142 Lysosome
    487633 (HEXA)
Enzymes [BR:cfa01000]
 3. Hydrolases
  3.2  Glycosylases
   3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
    3.2.1.52  beta-N-acetylhexosaminidase
     487633 (HEXA)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
30
AA seq 529 aa AA seqDB search
MAASGLWLPLLLAAALAGRAAALWPWPQYIQTSEAHYAIFPHDFQFRYHSSSAAQPGCSV
LDEAFQRYRDLLFSSRAWYPPEPTRKLHALEKNSLVVLVVTPGCNQLPSLESLENYTLTI
NDDHCFLLSETVWGALRGLETFSQLVWRSPEGMFLINKTEIEDFPRFSHRGLLLDTSRHY
LPLTTIMDTLDAMAYNKFNVFHWHLVDDSSFPYDSYTFPELTRKGSYNPATHIYTAQDVK
MVIEYARLRGIRVLAEFDTPGHTLSWGPGVPGLLTPCYSGSHPSGTFGPVNPILNSTYEF
MSSFFLEVSSVFPDFYLHLGGDEVDFTCWKSNPDIQNFMKEKGFGSDFKQLESYYIQTLL
NIVSAYDKGYVVWQEVFDNKVKVRPDTIIQVWREEMPVHYVKEMELITKAGFRALLSAPW
YLNHITYGPDWSEIYMVEPLEFKGSPQQKALVIGGEACMWGEYVDSTNLAPRLWPRAGAV
AERLWSNKLVTNLDSAFKRLTQFRCELLRRGVQAQPLNVGYCEQEFEQT
NT seq 1590 nt NT seq  +upstreamnt  +downstreamnt
atggcggcctcggggctctggcttccgctgctgctggcggcagcgctcgccggccgggcg
gcggccctgtggccctggccgcagtacatccagacctccgaggcgcactacgccatcttc
ccgcacgacttccagttccggtaccacagcagttcggccgcgcagccgggctgctccgtc
ctggacgaggctttccagcgctaccgcgacctgctcttcagctcccgcgcttggtaccct
cctgagcccacaagaaaactgcatgcactggaaaagaattcattggttgtccttgtggtc
actccaggatgtaaccagcttccttctttggagtcactggaaaattacactctgaccata
aatgatgatcattgtttcctcctgtctgagactgtctggggagctctccgaggtctggag
acttttagccaacttgtttggagatctccggagggcatgttccttatcaacaagaccgag
attgaagatttcccccgcttctcccaccgggggttgttgttggatacgtctcgccattac
ctgccactgactaccatcatggacactctggacgccatggcatacaataaattcaatgtg
ttccactggcatctggttgatgactcttccttcccatatgacagctacacttttccagag
ctcaccagaaagggatcctacaatcctgccacccatatctacacagcacaggatgtaaag
atggtgattgaatatgcacggcttcggggtatccgtgtgttggcagagtttgacactcct
ggccacactctgtcctggggaccaggtgtccctggattattgactccttgctactctggg
tctcatccttctggcacctttggaccagtgaatcccattctcaacagtacctatgaattc
atgagctcgtttttcttggaggtcagctctgtctttccagatttttatcttcaccttgga
ggagatgaggttgatttcacctgctggaagtccaacccagatatccagaactttatgaag
gaaaaaggctttggcagtgactttaagcagctggagtcctactacatccagacgctgctg
aacatcgtctctgcctatgacaagggctatgtggtgtggcaggaagtgtttgataataaa
gtaaaggttcggccggatacaatcattcaggtatggcgagaagagatgccagtacactat
gtgaaggagatggagctgatcaccaaagctggcttccgtgccctgctctctgccccctgg
tacctgaatcacataacttatggccctgactggagtgaaatctacatggtggagcccctg
gaatttaaaggaagtcctcagcagaaggctctagtgattggtggagaggcctgtatgtgg
ggagagtatgtggacagcacaaatctggcccccagactctggcccagagcaggggctgtg
gctgagaggctgtggagcaacaagttggtgactaacctggactctgcctttaaacgtttg
acacaattccgctgtgagctactaaggcgaggtgtccaggcccagcccctcaatgtaggc
tactgtgaacaggagtttgaacaaacctga

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