KEGG   Canis familiaris (dog): 489508Help
Entry
489508            CDS       T01007                                 

Gene name
MAP2K4
Definition
(RefSeq) mitogen-activated protein kinase kinase 4
  KO
K04430  
mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
Organism
cfa  Canis familiaris (dog)
Pathway
MAPK signaling pathway
ErbB signaling pathway
Toll-like receptor signaling pathway
Fc epsilon RI signaling pathway
TNF signaling pathway
GnRH signaling pathway
Relaxin signaling pathway
Chagas disease (American trypanosomiasis)
Hepatitis B
Influenza A
HTLV-I infection
Kaposi's sarcoma-associated herpesvirus infection
Epstein-Barr virus infection
Fluid shear stress and atherosclerosis
Module
MAPK (JNK) signaling
Brite
KEGG Orthology (KO) [BR:cfa00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    489508 (MAP2K4)
   04012 ErbB signaling pathway
    489508 (MAP2K4)
   04668 TNF signaling pathway
    489508 (MAP2K4)
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    489508 (MAP2K4)
   04664 Fc epsilon RI signaling pathway
    489508 (MAP2K4)
  Endocrine system
   04912 GnRH signaling pathway
    489508 (MAP2K4)
   04926 Relaxin signaling pathway
    489508 (MAP2K4)
 Human Diseases
  Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    489508 (MAP2K4)
  Infectious diseases
   05166 HTLV-I infection
    489508 (MAP2K4)
   05164 Influenza A
    489508 (MAP2K4)
   05161 Hepatitis B
    489508 (MAP2K4)
   05167 Kaposi's sarcoma-associated herpesvirus infection
    489508 (MAP2K4)
   05169 Epstein-Barr virus infection
    489508 (MAP2K4)
   05142 Chagas disease (American trypanosomiasis)
    489508 (MAP2K4)
Enzymes [BR:cfa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     489508 (MAP2K4)
Protein kinases [BR:cfa01001]
 Serine/threonine protein kinases: STE group
  STE7 family
   489508 (MAP2K4)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
Ensembl: 
Position
5
AA seq 438 aa AA seqDB search
MGTAANGPQYTVTTVWSHPSAKKIRAALLVNELELISFTLGFQINFCEKAQNRPIPESRS
GSHSQELSALILQSCPTGKRKALKLNFANPPFKSTARFTLNPNPTGVQNPHIERLRTHSI
ESSGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKE
QKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMELMSTSFDKFYKYVYSVLDDVIP
EEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKT
RDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVV
KGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRPKYKELLKHPFILMYEERTVEVACYV
CKILDQMPATPSSPMYVD
NT seq 1317 nt NT seq  +upstreamnt  +downstreamnt
atgggtactgctgccaatggaccacagtacacagtaactacagtatggagccaccctagt
gcaaagaaaatcagagccgccttactggtcaatgaactggaacttatctcttttacttta
ggctttcagataaacttctgtgaaaaggcacaaaacaggcccatccctgagagccgatcc
gggagtcacagccaggagctttctgctcttatcctacagtcctgtccaactggtaaacgc
aaagcactgaagttgaattttgcaaatccacctttcaaatctacagcaaggtttactctg
aatcccaaccctacaggagttcaaaacccacacatagagagactgagaacacacagcatt
gaatcatcaggaaagctgaagatctcccctgagcagcactgggatttcactgcggaggac
ttgaaagaccttggagaaattggacgaggagcttatggttctgtcaacaaaatggtccac
aaaccaagtgggcaaataatggcggtgaaaagaattcggtcaacagtggatgaaaaagaa
caaaaacagcttcttatggatttggatgtagtaatgcggagtagtgattgcccgtacatt
gttcagttttatggtgcactcttcagagagggtgactgttggatctgtatggaactcatg
tctacctcgtttgataagttttacaaatatgtatatagtgtattagatgatgttattcca
gaagaaattttaggcaaaatcactttagcaactgtgaaagcactaaaccacttaaaagaa
aacttgaaaatcattcacagagatatcaaaccttccaatattcttctggacaggagtggg
aatattaagctctgtgactttggcatcagtggacagctggtggactccattgccaagaca
agagatgccgggtgtaggccatatatggcacctgaaagaatagacccgagtgcatcacga
caaggatatgacgtccgctctgatgtctggagtttggggatcacattgtatgagttagcc
acaggccggtttccttatccaaagtggaatagtgtattcgatcaactcacacaagtcgtg
aaaggggaccctccacagctgagtaactctgaggaaagggaattctccccaagcttcatc
aactttgtcaacttgtgccttacgaaggatgaatccaaaaggccaaagtataaagaactt
ctgaaacatccctttattttgatgtatgaagaacgtaccgtagaggttgcctgctatgtt
tgtaaaatcctggatcaaatgccagctactcccagctctcccatgtacgttgattga

DBGET integrated database retrieval system