KEGG   Canis familiaris (dog): 489571Help
Entry
489571            CDS       T01007                                 

Gene name
PRKAA2
Definition
protein kinase, AMP-activated, alpha 2 catalytic subunit
Orthology
K07198  
5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
Organism
cfa  Canis familiaris (dog)
Pathway
FoxO signaling pathway
Regulation of autophagy
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Circadian rhythm
Insulin signaling pathway
Adipocytokine signaling pathway
Oxytocin signaling pathway
Non-alcoholic fatty liver disease (NAFLD)
Hypertrophic cardiomyopathy (HCM)
Brite
KEGG Orthology (KO) [BR:cfa00001]
 Environmental Information Processing
  Signal transduction
   04068 FoxO signaling pathway
    489571 (PRKAA2)
   04151 PI3K-Akt signaling pathway
    489571 (PRKAA2)
   04152 AMPK signaling pathway
    489571 (PRKAA2)
   04150 mTOR signaling pathway
    489571 (PRKAA2)
 Cellular Processes
  Transport and catabolism
   04140 Regulation of autophagy
    489571 (PRKAA2)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    489571 (PRKAA2)
   04920 Adipocytokine signaling pathway
    489571 (PRKAA2)
   04921 Oxytocin signaling pathway
    489571 (PRKAA2)
  Environmental adaptation
   04710 Circadian rhythm
    489571 (PRKAA2)
 Human Diseases
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    489571 (PRKAA2)
  Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    489571 (PRKAA2)
Enzymes [BR:cfa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     489571 (PRKAA2)
Protein kinases [BR:cfa01001]
 Serine/threonine protein kinases: CAMK group
  CAMKL family
   489571 (PRKAA2)
Mitochondrial biogenesis [BR:cfa03029]
 Mitochondrial quality control factors
  Regulator of mitochondrial biogenesis
   Other regulator of mitochondrial biogenesis
    489571 (PRKAA2)
  Mitophagy factors
   Other mitophagy factors
    489571 (PRKAA2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
5
AA seq 533 aa AA seqDB search
MDQSPRLRLPQKVGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKL
YQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEVEARRLFQQILSAVDYCHRHMVVHRD
LKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWS
CGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVDPLKRATI
KDIREHEWFKQDLPSYLFPEDPSYDANVIDDEAVKEVCEKFECTESEVMNSLYSGDPQDQ
LAVAYHLIIDNRRIMNQASEFYLASSPPTGSFMDDSTMHIPPGLKPHPERMPPLIADSPK
ARCPLDALNTTKPKSLAVKKAKWHLGIRSQSKPYDIMAEVYRAMKQLDFEWKVVNAYHLR
VRRKNPVTGNYVKMSLQLYLVDNRSYLLDFKSIDDEVVEQRSGSSTPQRSCSAAGLHRPR
SSFDSVTAEGHSLSGSLTGSLTGSTLSSVPPRLGSHTMDFFEMCASLITTLAR
NT seq 1602 nt NT seq  +upstreamnt  +downstreamnt
atggaccaaagccccagattaagattaccgcagaaagttggagaacatcaattgacaggc
cataaagtggcagttaaaatcttaaatagacagaagattcgcagtttagatgttgttgga
aaaataaaacgagaaattcaaaatctaaaactctttcgtcatcctcatattatcaaacta
taccaggtgatcagcactccaacagatttttttatggttatggaatatgtgtctggtggt
gaattatttgactacatctgtaaacatggacgggttgaagaggtggaagcaaggcgactc
tttcagcagattctgtcagctgtggattactgtcataggcatatggtggttcatcgagac
ctgaaaccagagaatgtgctgttggatgctcacatgaatgccaagatagctgattttggt
ttgtctaatatgatgtcagatggtgaatttctgagaactagttgtggatctccgaattat
gcagcacccgaagtcatctcgggcagattgtatgcaggtcctgaagttgatatctggagc
tgcggtgttattttgtatgcccttctttgtggcaccctcccatttgatgatgagcatgta
cctacgttatttaagaagatccgagggggtgttttttatatcccagaatatctcaatcgt
tctgttgccactctcttgatgcatatgctgcaagttgaccccctgaaacgagcaactatc
aaagatataagagagcatgaatggtttaaacaagatttgcccagttacttatttcctgaa
gacccctcctatgatgctaacgtcattgatgatgaggctgtgaaagaagtgtgtgaaaaa
tttgagtgtacagaatcagaagtaatgaacagtttatatagtggtgaccctcaagaccag
cttgcagtggcttatcatcttatcattgacaatcggagaataatgaaccaagccagtgag
ttctacctcgcctctagtcccccaactggttcttttatggatgatagtaccatgcatatt
cccccaggcctgaaacctcatccagaaaggatgccacctcttatagcagacagccctaaa
gcgagatgtccattggatgcactgaatacaactaagcccaaatctttagctgtgaaaaaa
gccaagtggcatcttggaatcagaagtcaaagcaaaccttatgacattatggctgaagtc
taccgagctatgaagcagctggattttgaatggaaggtagtgaatgcatatcatcttcgt
gtaagaagaaaaaatccagtgactggcaattatgtgaaaatgagtttacaactttacctg
gttgacaatagaagctatcttttggactttaaaagcattgatgatgaggtggtggagcag
aggtctggttcttcaacacctcagcgttcctgttctgctgctggcttacatagaccaagg
tcaagttttgactctgtgactgcggagggccattcactttctggctctcttaccggctct
ttgactggaagtacattgtcttctgttccaccccgcctaggcagtcacaccatggatttt
tttgaaatgtgtgccagtctgatcactactttagcccgttga

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