KEGG   Canis familiaris (dog): 489571Help
Entry
489571            CDS       T01007                                 

Gene name
PRKAA2
Definition
(RefSeq) protein kinase, AMP-activated, alpha 2 catalytic subunit
  KO
K07198  
5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
Organism
cfa  Canis familiaris (dog)
Pathway
FoxO signaling pathway
Regulation of autophagy
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Longevity regulating pathway
Longevity regulating pathway - multiple species
Circadian rhythm
Insulin signaling pathway
Adipocytokine signaling pathway
Oxytocin signaling pathway
Glucagon signaling pathway
Insulin resistance
Non-alcoholic fatty liver disease (NAFLD)
Hypertrophic cardiomyopathy (HCM)
Brite
KEGG Orthology (KO) [BR:cfa00001]
 Environmental Information Processing
  Signal transduction
   04068 FoxO signaling pathway
    489571 (PRKAA2)
   04151 PI3K-Akt signaling pathway
    489571 (PRKAA2)
   04152 AMPK signaling pathway
    489571 (PRKAA2)
   04150 mTOR signaling pathway
    489571 (PRKAA2)
 Cellular Processes
  Transport and catabolism
   04140 Regulation of autophagy
    489571 (PRKAA2)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    489571 (PRKAA2)
   04922 Glucagon signaling pathway
    489571 (PRKAA2)
   04920 Adipocytokine signaling pathway
    489571 (PRKAA2)
   04921 Oxytocin signaling pathway
    489571 (PRKAA2)
  Aging
   04211 Longevity regulating pathway - mammal
    489571 (PRKAA2)
   04213 Longevity regulating pathway - multiple species
    489571 (PRKAA2)
  Environmental adaptation
   04710 Circadian rhythm
    489571 (PRKAA2)
 Human Diseases
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    489571 (PRKAA2)
  Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    489571 (PRKAA2)
   04931 Insulin resistance
    489571 (PRKAA2)
Enzymes [BR:cfa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     489571 (PRKAA2)
Protein kinases [BR:cfa01001]
 Serine/threonine protein kinases: CAMK group
  CAMKL family
   489571 (PRKAA2)
Mitochondrial biogenesis [BR:cfa03029]
 Mitochondrial quality control factors
  Regulator of mitochondrial biogenesis
   Other regulator of mitochondrial biogenesis
    489571 (PRKAA2)
  Mitophagy factors
   Other mitophagy factors
    489571 (PRKAA2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
5
AA seq 462 aa AA seqDB search
MVMEYVSGGELFDYICKHGRVEEVEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAH
MNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCG
TLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVDPLKRATIKDIREHEWFKQ
DLPSYLFPEDPSYDANVIDDEAVKEVCEKFECTESEVMNSLYSGDPQDQLAVAYHLIIDN
RRIMNQASEFYLASSPPTGSFMDDSTMHIPPGLKPHPERMPPLIADSPKARCPLDALNTT
KPKSLAVKKAKWHLGIRSQSKPYDIMAEVYRAMKQLDFEWKVVNAYHLRVRRKNPVTGNY
VKMSLQLYLVDNRSYLLDFKSIDDEVVEQRSGSSTPQRSCSAAGLHRPRSSFDSVTAEGH
SLSGSLTGSLTGSTLSSVPPRLGSHTMDFFEMCASLITTLAR
NT seq 1389 nt NT seq  +upstreamnt  +downstreamnt
atggttatggaatatgtgtctggtggtgaattatttgactacatctgtaaacatggacgg
gttgaagaggtggaagcaaggcgactctttcagcagattctgtcagctgtggattactgt
cataggcatatggtggttcatcgagacctgaaaccagagaatgtgctgttggatgctcac
atgaatgccaagatagctgattttggtttgtctaatatgatgtcagatggtgaatttctg
agaactagttgtggatctccgaattatgcagcacccgaagtcatctcgggcagattgtat
gcaggtcctgaagttgatatctggagctgcggtgttattttgtatgcccttctttgtggc
accctcccatttgatgatgagcatgtacctacgttatttaagaagatccgagggggtgtt
ttttatatcccagaatatctcaatcgttctgttgccactctcttgatgcatatgctgcaa
gttgaccccctgaaacgagcaactatcaaagatataagagagcatgaatggtttaaacaa
gatttgcccagttacttatttcctgaagacccctcctatgatgctaacgtcattgatgat
gaggctgtgaaagaagtgtgtgaaaaatttgagtgtacagaatcagaagtaatgaacagt
ttatatagtggtgaccctcaagaccagcttgcagtggcttatcatcttatcattgacaat
cggagaataatgaaccaagccagtgagttctacctcgcctctagtcccccaactggttct
tttatggatgatagtaccatgcatattcccccaggcctgaaacctcatccagaaaggatg
ccacctcttatagcagacagccctaaagcgagatgtccattggatgcactgaatacaact
aagcccaaatctttagctgtgaaaaaagccaagtggcatcttggaatcagaagtcaaagc
aaaccttatgacattatggctgaagtctaccgagctatgaagcagctggattttgaatgg
aaggtagtgaatgcatatcatcttcgtgtaagaagaaaaaatccagtgactggcaattat
gtgaaaatgagtttacaactttacctggttgacaatagaagctatcttttggactttaaa
agcattgatgatgaggtggtggagcagaggtctggttcttcaacacctcagcgttcctgt
tctgctgctggcttacatagaccaaggtcaagttttgactctgtgactgcggagggccat
tcactttctggctctcttaccggctctttgactggaagtacattgtcttctgttccaccc
cgcctaggcagtcacaccatggatttttttgaaatgtgtgccagtctgatcactacttta
gcccgttga

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