KEGG   Canis familiaris (dog): 490682Help
Entry
490682            CDS       T01007                                 

Gene name
SOS2
Definition
son of sevenless homolog 2 (Drosophila)
Orthology
K03099  
son of sevenless
Organism
cfa  Canis familiaris (dog)
Pathway
MAPK signaling pathway
ErbB signaling pathway
Ras signaling pathway
Chemokine signaling pathway
FoxO signaling pathway
PI3K-Akt signaling pathway
Dorso-ventral axis formation
Focal adhesion
Gap junction
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Neurotrophin signaling pathway
Regulation of actin cytoskeleton
Insulin signaling pathway
GnRH signaling pathway
Estrogen signaling pathway
Prolactin signaling pathway
Alcoholism
Hepatitis C
Pathways in cancer
Proteoglycans in cancer
MicroRNAs in cancer
Renal cell carcinoma
Endometrial cancer
Glioma
Prostate cancer
Chronic myeloid leukemia
Acute myeloid leukemia
Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:cfa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    490682 (SOS2)
   04010 MAPK signaling pathway
    490682 (SOS2)
   04012 ErbB signaling pathway
    490682 (SOS2)
   04630 Jak-STAT signaling pathway
    490682 (SOS2)
   04068 FoxO signaling pathway
    490682 (SOS2)
   04151 PI3K-Akt signaling pathway
    490682 (SOS2)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    490682 (SOS2)
  Cellular commiunity
   04510 Focal adhesion
    490682 (SOS2)
   04540 Gap junction
    490682 (SOS2)
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    490682 (SOS2)
   04660 T cell receptor signaling pathway
    490682 (SOS2)
   04662 B cell receptor signaling pathway
    490682 (SOS2)
   04664 Fc epsilon RI signaling pathway
    490682 (SOS2)
   04062 Chemokine signaling pathway
    490682 (SOS2)
  Endocrine system
   04910 Insulin signaling pathway
    490682 (SOS2)
   04912 GnRH signaling pathway
    490682 (SOS2)
   04915 Estrogen signaling pathway
    490682 (SOS2)
   04917 Prolactin signaling pathway
    490682 (SOS2)
  Nervous system
   04722 Neurotrophin signaling pathway
    490682 (SOS2)
  Development
   04320 Dorso-ventral axis formation
    490682 (SOS2)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    490682 (SOS2)
   05206 MicroRNAs in cancer
    490682 (SOS2)
   05205 Proteoglycans in cancer
    490682 (SOS2)
   05214 Glioma
    490682 (SOS2)
   05221 Acute myeloid leukemia
    490682 (SOS2)
   05220 Chronic myeloid leukemia
    490682 (SOS2)
   05211 Renal cell carcinoma
    490682 (SOS2)
   05215 Prostate cancer
    490682 (SOS2)
   05213 Endometrial cancer
    490682 (SOS2)
   05223 Non-small cell lung cancer
    490682 (SOS2)
  Substance dependence
   05034 Alcoholism
    490682 (SOS2)
  Infectious diseases
   05160 Hepatitis C
    490682 (SOS2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
8
AA seq 1272 aa AA seqDB search
MAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY
KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD
IGLVCLCEDEPSSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDRNLFKPSDI
DRIFSNISDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDI
LSPKFNEHFSKLMARPAVALHFQSIADGFKEAVRYVLPRLMLVPVYHCWHYFELLKQLKA
CSEEQEDRECLNQAITALMNLQGSMDRIYKQYSPRRRPGDPVCPFYNRQLRSKHLAIKKM
NEIQKNIDGWEGKDIGQCCNEFIMEGPLTRIGAKHERHIFLFDGLMISCKPNHSQSRLPG
YSNAEYRLKEKFIMRKTQICDKEDTCECKHAFELISKDENSIIFAAKSAEEKNNWMAALI
SLHYRSTLDRMLDSVLLKEENEQPLRLPSPEVYRFVVKDSEENIVFEDNLQSRSGIPIIK
GGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADKLA
VEKGEQPISADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISSVR
GKAMKKWVESIAKIIKRKKQAQANGISHNITFESPPPPIEWHISRPGQFETFDLMTLHPI
EIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEA
ENFEERVAILSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRRILD
EAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKRR
KVAEITGEIQQYQNQPYCLRIEPEMRRFFENLNPMGNASEKEFTDYLFNKSLEIEPRNCK
QPPRFPRKSTFSLKSPGIRPNTGRHGSTSGTLRGHPMPLEREPYKISFSRIAETDLESTV
SAPTSPNTPSTPPVSASSDLSVFLDVDLNSSCGSNSIFAPVLLPHSKSFFSSCGSLHKLS
EEPLIPPPLPPRKKFDHDASNSKGNTKSDDDPPAIPPRQPPPPKVKPRVPAPTGAFDGPL
HSPPPPPPRDPLPDTPPPVPLRPPEHFINCPFNLQPPPLGHLHRDPDWFRDVSTCPNSPN
TPPSTPSPRVPRRCYLLSSSHNNLAHPQAPPVPPRQNSSPHLPKLPPKTYKRELSHPPSY
RLPLLENAETPQ
NT seq 3819 nt NT seq  +upstreamnt  +downstreamnt
atggctcaaccaaggactgttcaagatgtggaggaacgtgttcaaaagacctttcctcat
ccaattgataaatgggctattgctgatgcacaatctgccatagaaaaacgaaaacgaaga
aatcctctcttactgcctgtggacaaaatccatccttcattgaaggaagttttagggtac
aaagtggactatcatgtatccctgtatattgtggctgtactagagtatatctcagctgat
attttgaagttggctggtaattatgtttttaatatccgacattatgaaatatctcagcag
gacattaaagtatcaatgtgtgcagataaggttttgatggacatgtttgatcaggatgac
ataggtttggtttgtctttgtgaagatgaacctagttcttcaggtgaattaaactactat
gaccttgtcagaactgaaattgcagaagaaaggcaatatctacgggaactaaatatgatc
ataaaagtgtttcgagaagcctttctttcggacagaaatctgtttaaaccttctgatatt
gacagaattttcagtaacatttcagatatacacgaattgactgtgaaacttctaggtttg
attgaagacacagtggaaatgactgatgaaagcagtcctcatcccttagctggcagctgt
tttgaagatttggcagaggagcaagcatttgatccttatgaaacattatcacaggacatt
ctttctccaaaatttaatgaacatttcagtaagctgatggccagacctgcagtggctcta
cactttcagtccattgctgatggttttaaagaggcagttcgttatgtccttccacgcctt
atgctagtgcctgtttatcattgttggcactattttgaattattaaagcaattgaaagca
tgtagtgaagagcaggaagacagagaatgtttgaaccaagctattacagctcttatgaat
ctccagggtagcatggaccgaatttataagcagtattcacctagacgccgacctggggat
cctgtttgccctttttataatcgtcaattaagaagcaagcatctagctattaaaaaaatg
aatgaaattcagaaaaacatagatgggtgggaaggcaaagatattggacagtgttgtaat
gaattcattatggaaggtccattgacacgaattggtgctaaacatgaacgacatattttt
ctctttgatggcttaatgattagctgtaagcccaatcatagccagtcacgccttccaggt
tacagtaatgcagaatacagattaaaagaaaaatttatcatgaggaagacacagatatgt
gataaagaagatacttgtgagtgcaaacacgcttttgagttgatatccaaggatgaaaac
agcataatatttgctgctaaatcggctgaagagaaaaataattggatggccgcacttatt
tctcttcactatcgtagtacactagatcgaatgctagattcagtgttattgaaagaagaa
aatgagcaaccattgagattaccaagtcctgaagtatatcgttttgtggtaaaagactct
gaggaaaacattgtttttgaagacaacttgcaaagtagaagtggaattcccattattaaa
ggaggaactgtggtgaaattaattgaaagattaacatatcatatgtatgcagatcccaat
tttgttcgtacttttcttactacataccgttcattttgtaaaccacaggaattgctaagc
ttactgattgaacgatttgaaatcccagagccggaacctactgaagcagataaattggct
gtagagaaaggcgaacagccaatcagtgcagaccttaaaaggtttcgcaaggaatatgtc
caaccagtacaacttaggatcttaaatgtatttcggcactgggttgaacaccacttttat
gactttgaaagggatttggagttgcttgaaagactagaatccttcatttcaagtgtaaga
ggaaaagctatgaagaaatgggtagagtcaattgctaagatcatcaagaggaagaaacaa
gctcaggcaaatggaataagccataatattacctttgaaagtccacctccaccaattgaa
tggcatatcagcagaccaggacagtttgaaacatttgatctcatgacactgcatccaata
gaaattgcacgtcagctgacacttttggaatctgatctctacaggaaagtccaaccttct
gaacttgtagggagtgtatggaccaaagaagataaagaaataaattctccaaatttatta
aaaatgattcgccataccacgaatctcaccctttggtttgaaaagtgcattgtggaagca
gaaaattttgaagaacgggtggcaatactaagcagaattatagaaattctgcaagttttt
caagatttgaataatttcaatggtgtattggagatagtcagtgcagtaaattcagtatca
gtgtacagactagaccatacttttgaggcattgcaggaaagaaaaaggagaattttggat
gaagctgtggaattaagtcaagatcactttaaaaaatacctagtaaaacttaagtcaatc
aatccaccttgtgtgcctttttttggaatatatttaacaaatattctgaaaactgaagaa
gggaataatgattttttaaaaaagaaagggaaagatttaatcaatttcagtaagaggagg
aaagtagctgaaattactggagaaattcagcagtatcagaatcaaccttactgtttacgg
atagaaccagaaatgaggagattctttgaaaaccttaaccccatgggaaatgcttctgaa
aaggagtttacagattatttgttcaacaagtcactagaaattgagccccgaaactgcaaa
cagccacctcgatttcctaggaaatcaactttctctttaaaatctcctggaatacggccg
aatacaggccgacatggctctacctcaggcactttacgaggtcatccaatgccgttagaa
agagaaccatataaaataagctttagtcggattgctgaaactgatcttgaatcaactgtg
tcagcaccaacctctccaaatacaccatctactccaccagtatctgcttcttcagacctt
agtgtgtttttagatgtggatctcaacagttcctgtggcagcaatagcatctttgctcca
gtcctcttgccgcattcaaagtctttcttcagttcatgtggtagtttacataaactaagt
gaagagccactgattcctcctcctcttcctcctcgaaaaaagtttgatcatgatgcttca
aattccaagggaaatacgaaatctgatgatgacccccctgctattccaccaagacaacct
cctcctccaaaggtaaaaccgagagttcctgctcctactggtgcatttgatgggcctctg
catagtccacctccaccgccaccaagagatcctcttcctgatacccctccgccagttccc
cttcgtcctccagaacactttataaactgtccatttaatcttcagccacctccactagga
catctgcacagagatccagactggttcagagacgttagtacctgcccaaattcgccaaat
actcctcccagcacgccctctccaagagtaccacgtcgatgctacctgctcagttctagt
cacaacaaccttgctcatcctcaagctccccctgtgccaccgaggcagaactcaagcccg
cacctaccaaaactgccaccaaagacttataaacgggagctttcacaccccccgtcatac
agactgcctttactagaaaatgcagaaactcctcaatga

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