KEGG   Canis familiaris (dog): 606490Help
Entry
606490            CDS       T01007                                 

Gene name
GCK
Definition
glucokinase (hexokinase 4)
Orthology
K12407  
glucokinase [EC:2.7.1.2]
Organism
cfa  Canis familiaris (dog)
Pathway
Glycolysis / Gluconeogenesis
Galactose metabolism
Starch and sucrose metabolism
Amino sugar and nucleotide sugar metabolism
Butirosin and neomycin biosynthesis
Metabolic pathways
Carbon metabolism
Insulin signaling pathway
Insulin secretion
Prolactin signaling pathway
Type II diabetes mellitus
Maturity onset diabetes of the young
Module
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
Nucleotide sugar biosynthesis, glucose => UDP-glucose
Class
Metabolism; Overview; Carbon metabolism [PATH:cfa01200]
Metabolism; Carbohydrate metabolism; Glycolysis / Gluconeogenesis [PATH:cfa00010]
Metabolism; Carbohydrate metabolism; Galactose metabolism [PATH:cfa00052]
Metabolism; Carbohydrate metabolism; Starch and sucrose metabolism [PATH:cfa00500]
Metabolism; Carbohydrate metabolism; Amino sugar and nucleotide sugar metabolism [PATH:cfa00520]
Metabolism; Biosynthesis of other secondary metabolites; Butirosin and neomycin biosynthesis [PATH:cfa00524]
Organismal Systems; Endocrine system; Insulin secretion [PATH:cfa04911]
Organismal Systems; Endocrine system; Insulin signaling pathway [PATH:cfa04910]
Organismal Systems; Endocrine system; Prolactin signaling pathway [PATH:cfa04917]
Human Diseases; Endocrine and metabolic diseases; Type II diabetes mellitus [PATH:cfa04930]
Human Diseases; Endocrine and metabolic diseases; Maturity onset diabetes of the young [PATH:cfa04950]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
Un
AA seq 303 aa AA seqDB search
MLDDRARMDVTKKEKAEQILADFQMQEADLKKVMRRMQREMARGLRLETHEEASVKMLPT
YVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHEMYSIPEDAMTGTAE
MLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNN
IVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDRRCEVGMIVGTGCNACYXEEMQN
VELVEGTRPGRQREAGQPVAHHVYSPRPPALLCSTEQRVVHWTPEAAPKGTVVATASAHG
SGV
NT seq 912 nt NT seq  +upstreamnt  +downstreamnt
atgctggatgacagagccaggatggacgtcaccaagaaggaaaaggcagagcagatcctg
gcggacttccagatgcaggaggcggacttgaagaaggtgatgcggcggatgcagagggag
atggcgcggggcctgcggctggagacccacgaggaggccagcgtgaagatgctgcccacc
tacgtgcgctccaccccagaaggctcagaagtcggggacttcctctccctggacctgggc
ggcaccaacttcagggtgatgctggtcaaggtgggggagggcgaggaggggcagtggagt
gtgaaaaccaagcacgagatgtattccatccctgaagatgccatgactggtactgctgag
atgctctttgactacatctccgagtgcatctccgatttcctggacaagcatcagatgaag
cacaagaagctgcccttgggcttcaccttctcctttcctgtgaggcatgaagacatcgac
aagggcatcctcctcaattggaccaagggcttcaaagcatcaggagcagaggggaacaac
atcgtggggctcctccgtgacgccatcaaacgcagaggggactttgaaatggacgtggta
gcaatggtgaacgacacggtggccacgatgatctcttgctactatgaagaccgccggtgt
gaggttggcatgattgtgggcacaggctgtaacgcctgctacnatgaggagatgcagaac
gtggagctggtggaagggacgaggccgggccggcagagggaggctgggcagccagtggcc
catcacgtttattctccaaggcccccagcccttctctgctccacagagcagagggtagtg
cactggactccagaagcagcacccaaaggtactgttgtggccacggccagtgcccatggg
tctggggtgtag

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