KEGG   Camelus ferus (Wild Bactrian camel): 102504065
Entry
102504065         CDS       T02979                                 
Symbol
MTHFD1
Name
(RefSeq) C-1-tetrahydrofolate synthase, cytoplasmic isoform X1
  KO
K00288  methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]
Organism
cfr  Camelus ferus (Wild Bactrian camel)
Pathway
cfr00670  One carbon pool by folate
cfr01100  Metabolic pathways
cfr01240  Biosynthesis of cofactors
Module
cfr_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:cfr00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    102504065 (MTHFD1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:cfr04147]
    102504065 (MTHFD1)
Enzymes [BR:cfr01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     102504065 (MTHFD1)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     102504065 (MTHFD1)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.3  formate---tetrahydrofolate ligase
     102504065 (MTHFD1)
Exosome [BR:cfr04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   102504065 (MTHFD1)
SSDB
Motif
Pfam: FTHFS THF_DHG_CYH_C THF_DHG_CYH
Other DBs
NCBI-GeneID: 102504065
NCBI-ProteinID: XP_006177818
UniProt: A0A8B6Y9J8
Position
6:62324095..62375656
AA seq 935 aa
MAPAEILNGKVISAQIREKLKNQITQMKEQVPGFSPGLAILQVGNRDDSNLYISVKLKAA
EEVGIKVKHIKLPRTATESEVLKCITSLNEDLTVHGFIVQLPLDSENPINTEALVNAIAP
EKDVDGLSSINAGKLARGDLNDCFIPCTPKGCLELIKETGVKIAGRHAVVVGRSKIVGAP
MHDLLLWNHATVTTCHSRTANLNEEVNKGDILVVAVGQPEMVKGEWIKPGAIVIDCGINY
VPDNTKASGRRVVGDVSYNEAKERASFITPVPGGVGPMTVAMLMESTVESAKRFLEKCKP
GKWIIQYNKLNLKTPVPSDIDISRACKPKPIGNLAREIGLFSEEVELYGETKAKVLLSAL
ERLKHQPDGKYVVVTGITPTPLGEGKSTTTIGLVQAFGAHLHQNVFACVRQPSQGPTFGI
KGGAAGGGYSQVIPMEEFNLHLTGDIHAITAANNLVAAAIDARMFHEQTQTDKALFNRLV
PSVNGVRTFSDIQIRRLQRLGIEKTDPTTLTDEEINRFARLDIDPETITWQRVLDTNDRF
LRKITIGQAPTEKGHTRMTQFDISVASEIMAVLALTSSLEDMRERLSKMVVASSKKGEPI
STEDLGVSGALTVLMKDAIKPNLMQTLEGTPVFVHAGPFANIAHGNSSIIADQVALKLVG
PEGFVVTEAGFGADIGMEKFFNIKCRYSGLRPHVVVLVATVRALKMHGGGPTVTAGLPLP
KAYIEENLELVEKGFSNLRKQIENARMFGVPVVVAVNAFKTDTEAELDLVSQLAREHGAF
DAVKCTHWAEGGKGALALAQAVQRAAEAPSSFQLLYDLKLPVEDKIRIIAQKIYGADDIE
LLPEAQHKAEVYTKQGFGDLPICMAKTHLSLSHNPELKGMPTGFVLPIRDIRASVGAGFL
YPLVGTMSTMPGLPTRPCFYDIDLDPETEQVNGLF
NT seq 2808 nt   +upstreamnt  +downstreamnt
atggcgccggcggaaatcctgaacgggaaggtgatctcagcacaaataagggagaaactg
aagaaccaaatcactcagatgaaggagcaagtacctggtttctcaccaggtctggcaatt
ttacaggttggcaacagagatgattctaacctttatataagtgtgaagctgaaggctgct
gaagaggttgggatcaaagtcaagcacattaagttaccacgcacggccacagaatctgag
gtgttaaagtgcattacgtctttgaatgaagacctcactgtacatgggttcatagtgcag
ctacctttagattcagagaatcccattaacactgaagcactggtcaatgctattgcaccc
gaaaaggatgtggacggactgagtagcatcaatgctggaaaacttgctagaggtgacctc
aatgactgtttcatcccttgtacacccaaaggatgcttggaactcatcaaagagacaggg
gtaaagattgccgggaggcatgctgttgtggtcgggcgcagcaagatagttggtgccccg
atgcatgacttgcttctgtggaaccatgccacagtgaccacctgccactccaggactgcc
aatctaaatgaggaggtaaataaaggtgacatcctggtagttgcagtgggtcagcctgaa
atggtgaaaggggagtggatcaaacctggggcgatagtcatcgactgtggaatcaattat
gtcccagacaatacaaaagcaagtgggaggagagttgtgggtgacgtgtcatacaacgag
gccaaggagagggcgagcttcatcacccccgttcctggaggcgttgggcccatgacagtg
gcgatgctaatggagagcacggtagagagtgcaaagcgtttcctggagaaatgtaagccg
ggaaagtggatcattcagtataacaaacttaacctcaagacacccgtgccaagtgacatc
gatatatcacgggcttgcaagccaaagcccattggtaacctggctcgagaaattggtctg
ttctctgaagaggtagaattgtatggtgaaaccaaggccaaagtcctgctgtcagcgctg
gaacgcctgaaacaccagcctgacgggaaatacgtggtggtgaccggaataactccaaca
cccttgggcgaggggaaaagcacaaccacgattgggctggtgcaggccttcggtgcccat
ctccatcagaacgtcttcgcatgcgtgagacagccttcacagggccccaccttcggaata
aaaggtggcgctgcaggcggtggctactcacaggtcattccaatggaagagtttaatctc
cacctcactggtgacatccacgccatcactgcagcgaataacctcgttgctgcagccatc
gacgcccggatgttccacgaacagacccagacagacaaggctctctttaatcgtttggta
ccatcagtaaatggagtgagaacgttctctgatatccaaatccgaaggttacagagacta
ggcatcgaaaagaccgaccctaccacactgacagatgaagagataaacagatttgcaaga
ctggacattgatccggaaactataacttggcaaagagtgttggataccaacgatagattc
ctgaggaagatcacaattggacaggctccgacggagaaggggcacacacggatgacccag
tttgatatctctgtggccagtgaaatcatggctgtcctggctctcaccagttctctagaa
gacatgagagagagactgagcaaaatggtggtggcatccagcaagaaaggggagcccatc
agcactgaagacctgggagtgagtggggcattgacggtgcttatgaaggacgccatcaag
cccaatctcatgcagacacttgagggcactccagtgtttgttcacgcggggccgttcgcc
aacatcgcgcacgggaattcttccatcatcgcagaccaggtcgcactcaagcttgttggt
cctgaagggtttgtagtgaccgaagcaggatttggagcagacattggaatggaaaagttc
tttaacatcaagtgccggtattcgggcctccgccctcacgtggtggtgcttgttgccact
gtcagggctctgaagatgcacggaggcggccccacggtgactgctggacttcctcttccc
aaggcttacatagaggagaacctggagctggttgaaaaaggcttcagtaacttgaggaaa
caaattgaaaatgccagaatgtttggagttccagtagtagtggctgtgaatgccttcaag
acagatacggaggccgagctggatctcgtcagccaacttgccagagagcatggggccttt
gatgcagtgaagtgcactcactgggcagaagggggcaagggcgccctggcgctggctcag
gccgtccagagagcagctgaggcgcccagcagcttccagctcctctatgacctcaagctc
cctgttgaggataaaatcaggatcattgcacagaagatctatggggcagatgacattgaa
ttgctccctgaagcacagcacaaagctgaagtctacacaaagcagggctttggggacctg
cccatctgcatggccaagacacacctgtccttgtctcacaacccagagctcaaaggcatg
cccacaggcttcgtcctgcccattagagacatccgtgccagtgtcggggctggttttctg
taccctctggtgggaacgatgagcaccatgcctggactccctacccggccctgtttctat
gatattgatttggaccctgaaactgagcaggtgaatgggctgttctaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Chemical substance (12)   
   KEGG COMPOUND (12)   
Chemical reaction (6)   
   KEGG ENZYME (3)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (3)   
   Pfam (3)   
All databases (46)   

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