| Entry |
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| Definition |
(RefSeq) steroid 21-hydroxylase
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| KO |
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| Organism |
cfr Camelus ferus (Wild Bactrian camel)
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| Pathway |
| Steroid hormone biosynthesis | | Metabolic pathways | | Aldosterone synthesis and secretion | | Cortisol synthesis and secretion | | Cushing's syndrome |
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| Module |
| C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone |
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| Brite |
KEGG Orthology (KO) [BR:cfr00001]
Metabolism
Lipid metabolism
00140 Steroid hormone biosynthesis
102506530
Organismal Systems
Endocrine system
04925 Aldosterone synthesis and secretion
102506530
04927 Cortisol synthesis and secretion
102506530
Human Diseases
Endocrine and metabolic diseases
04934 Cushing's syndrome
102506530
Enzymes [BR:cfr01000]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
1.14.14.16 steroid 21-monooxygenase
102506530
Cytochrome P450 [BR:cfr00199]
Cytochrome P450, animal type
CYP21 family
102506530
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| SSDB |
   |
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| Motif |
 |
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| Other DBs |
NCBI-GeneID: NCBI-ProteinID: |
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| Position |
Un
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| AA seq |
318 aa  
MVPVGLLLLPLLLALLAGARLLWGQWKLRSLHLPPLVPGFLHLLQPNLPIYLLGLTQKLG
PIYRVRLGLQDVVVLNSKRTIEEAMVRKWVDFAGRPQIPSYKLVSQHCEDISLGDYSLLW
KAHKKLTRSALLLGIRNSMEPWVEQLTQEFCERMRAQAGAPVTIQKEFSFLTCSIICYLT
FGDKEETLVHAIHDCVQDLMKTWDHWSLQMLDMVPFLRFFPNPSLWRLKQALENRDHIVE
KQLRRHKESMVAGQWRDMVDYMLQGVGRPREGEGPGQLLEGHVHMSVVDLFIGGTETTAI
TLSWAVAFLLHHPELAPP |
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| NT seq |
957 nt  +upstreamnt +downstreamnt
atggtccccgtggggctgctgctgctgccgctgctgctggccctgctagccggggctcgc
ctgctgtggggccagtggaagctcaggagcctccacctcccccctcttgttcctggcttc
ttgcacctgctgcagcccaacctccccatctatctacttggcctgactcagaaactcggg
cctatctacagggtccgccttgggctgcaagatgtggtggtgctgaactccaagaggacc
attgaggaggccatggtcaggaagtgggtggacttcgctggcagaccccagataccatcc
tacaagctggtgtctcagcactgtgaggacatctccctgggggactactccctgctctgg
aaggcccacaagaagctcacccgctctgccctgctgctgggcatccgcaactccatggag
ccctgggtggagcagctgacccaggagttctgtgagcgcatgagagcccaggccggtgcc
cctgtgactatccagaaggaattctctttcctcacctgcagcatcatctgttaccttacc
tttggagacaaggaggagaccttagtacatgccattcatgactgtgtccaagacttgatg
aaaacctgggaccactggtccctccaaatgttggacatggttccctttctcaggttcttc
cccaaccccagcctctggaggctgaagcaggccttggagaacagggaccacattgtagag
aagcagctgaggcggcacaaggagagcatggtggccggccagtggagggacatggtggac
tacatgctccaaggggtggggaggccaagagagggagagggccctggacagctcctcgaa
gggcacgtgcatatgtctgtggtggaccttttcatcggtggcactgagaccacggcgata
accctttcctgggctgtggccttcctgcttcaccaccctgagctggctccaccctga |
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